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The map label for this gene is pyrR [H]

Identifier: 37520396

GI number: 37520396

Start: 885829

End: 886359

Strand: Direct

Name: pyrR [H]

Synonym: glr0827

Alternate gene names: 37520396

Gene position: 885829-886359 (Clockwise)

Preceding gene: 37520392

Following gene: 37520397

Centisome position: 19.01

GC content: 66.29

Gene sequence:

>531_bases
ATGAGTCGCGAGCCTGTCGAGATCCTCTCCGCCGCCGAGTTGCGACGCACGCTCCAGCGGCTTGCCACCCAAATTATCGA
GAACAACCGCGGTGTAGAAGATCTGGTGCTGTTGGGCATCTACACGCGGGGGGTACCCCTGGCCGAACGGCTCGGTCGGC
TCATCGACGGCCTGGAGAACACCAGCGTGCCGGTGGGTGCCCTCGATATCACCCTCTACCGCGACGATCTGCGCGACATC
GGTGTCAGGCCCCTCAGCCGCAGCGAAATCCCCTGCGACGTCACCGAGCGCAACGTCTATCTTGTCGACGATGTCATCTA
CCGGGGACGCACCGTGCGCGCCGCCCTCGACGCGCTCACCGACTACGGCCGTCCCGCCGCCATTCGCCTCGCGGTCCTCG
TCGATCGCGGCTGGCGGGATCTGCCCATCCACCCGGATCTGGTGGGCCGCCAATTGCCCACCGCCCGCCACGAACAGGTC
AAGGTGCTGCTCGAAGAGATCGACGGCCGCGACGGCGTGCTGCTGTACTGA

Upstream 100 bases:

>100_bases
ACCGGCCCAGTGCATCGTGTCTGAGGCAAAACCGGCCATGCTCAATGCCTCCTTGTTGTGACGAACGCCAGAAGGTCTGT
CCCCAAGATAGTATGTCCCA

Downstream 100 bases:

>100_bases
ACTTGCCGCCGATGATTTGTGGTGATAGGCTGGGACACTGTTGAGCATTCGCAAAAACCAATCATGAACGCCCAGGAGAT
CATCCGCTCGATCGAAGCGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSREPVEILSAAELRRTLQRLATQIIENNRGVEDLVLLGIYTRGVPLAERLGRLIDGLENTSVPVGALDITLYRDDLRDI
GVRPLSRSEIPCDVTERNVYLVDDVIYRGRTVRAALDALTDYGRPAAIRLAVLVDRGWRDLPIHPDLVGRQLPTARHEQV
KVLLEEIDGRDGVLLY

Sequences:

>Translated_176_residues
MSREPVEILSAAELRRTLQRLATQIIENNRGVEDLVLLGIYTRGVPLAERLGRLIDGLENTSVPVGALDITLYRDDLRDI
GVRPLSRSEIPCDVTERNVYLVDDVIYRGRTVRAALDALTDYGRPAAIRLAVLVDRGWRDLPIHPDLVGRQLPTARHEQV
KVLLEEIDGRDGVLLY
>Mature_175_residues
SREPVEILSAAELRRTLQRLATQIIENNRGVEDLVLLGIYTRGVPLAERLGRLIDGLENTSVPVGALDITLYRDDLRDIG
VRPLSRSEIPCDVTERNVYLVDDVIYRGRTVRAALDALTDYGRPAAIRLAVLVDRGWRDLPIHPDLVGRQLPTARHEQVK
VLLEEIDGRDGVLLY

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19784; Mature: 19653

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREPVEILSAAELRRTLQRLATQIIENNRGVEDLVLLGIYTRGVPLAERLGRLIDGLEN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
TSVPVGALDITLYRDDLRDIGVRPLSRSEIPCDVTERNVYLVDDVIYRGRTVRAALDALT
CCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHHHHHH
DYGRPAAIRLAVLVDRGWRDLPIHPDLVGRQLPTARHEQVKVLLEEIDGRDGVLLY
HCCCCHHEEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure 
SREPVEILSAAELRRTLQRLATQIIENNRGVEDLVLLGIYTRGVPLAERLGRLIDGLEN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
TSVPVGALDITLYRDDLRDIGVRPLSRSEIPCDVTERNVYLVDDVIYRGRTVRAALDALT
CCCCCCEEEEEEEHHHHHHCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHHHHHH
DYGRPAAIRLAVLVDRGWRDLPIHPDLVGRQLPTARHEQVKVLLEEIDGRDGVLLY
HCCCCHHEEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA