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The map label for this gene is trxB [H]

Identifier: 37520288

GI number: 37520288

Start: 763395

End: 764348

Strand: Direct

Name: trxB [H]

Synonym: glr0719

Alternate gene names: 37520288

Gene position: 763395-764348 (Clockwise)

Preceding gene: 37520287

Following gene: 37520292

Centisome position: 16.39

GC content: 64.05

Gene sequence:

>954_bases
ATGGAACAGTTCGATTTTGACGTGGTAATCGTAGGCGGTGGTCCGGCCGGTTGTACGTGTGCGCTGTACACTGCCCGCTC
CGAACTCAAGACGGTCATTCTGGACAAGAACCCGGCGGCCGGCGCCCTTGCCATCACCCACAAGATTGCCAATTACCCCG
GGGTGCCCGGGGAGATGAGCGGCGATCACCTGCTTGAAGTGATGCGCGATCAGGCCGTCGAATTCGGAACTGTTTACCGG
CGCGCCCAGGTCTACGGCCTCGACCTCAGCGAACCGGTCAAAAAAGTCTATACCCCAGAAGGGATCTTCACCGGTCGTGC
CCTGGTGCTCGCCACCGGGGCGATGGGCCGCATCGCGTCGATTCCCGGCGAGGCGGAGTACCTGGGGCGGGGGGTGAGCT
ACTGCGCCACCTGCGACGGGGCCTTTTACCGCAACCGCGAGGTGGTGGTGGTCGGCCTCAACCCCGAGGCCGTCGAAGAG
GCCCAGGTGCTCACCAAATTTGCTTCGACGGTGCACTGGATCACCCCCAAAGACCCCCACACTCTGGACGGCCACGCCGA
CGAGCTGCTGGCCCACCCGTCGGTCAAGCTCTGGGAGAAGACGCGCCTGATTCGCATCAAGGGCGAGGAGGCGGGGGTGA
CCGCCGTCGAGGTGCGCCATCCGGGCGAATCCGATAGCCAGGAGTTGCTGGCGGAAGGGGTGTTTGTCTACCTGCAAGGC
TCGAAGCCGATCACCGACTTCGTGGCGGGCCAGGTCGAAATGAAACCCGACGGCGGCGTCTGGGTAGATGAAATGATGCA
GACTTCGGTACCCGGCGTCTGGGGCATCGGCGACATTCGCAACACGCCCTTTAAGCAGGCGGTGGTGGCGGCGGGGGACG
GCTGCATCGCGGCGATGGCCATCGACCGCTTCCTCAATAGCCGCAAGGCGATCAAGCCCGACTGGGCGCACTAA

Upstream 100 bases:

>100_bases
CCTGTGGCTTCTCGGCACAGGCAAGTACGCATTTTGACTGCGATCCATTTGAGAACTAACCTGAGGGGTAGGCCAACAGG
CCAGTCGGGAGGGAGCGGCG

Downstream 100 bases:

>100_bases
CCAGCTCAGGCAAAGCGCACCCCGGCGGCTTCGACGACGGCACCTATACGCAATACCTGTTCGCCCTGCTTGGCCAGATA
GGCTTGAAGCGCATCCGCCT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MEQFDFDVVIVGGGPAGCTCALYTARSELKTVILDKNPAAGALAITHKIANYPGVPGEMSGDHLLEVMRDQAVEFGTVYR
RAQVYGLDLSEPVKKVYTPEGIFTGRALVLATGAMGRIASIPGEAEYLGRGVSYCATCDGAFYRNREVVVVGLNPEAVEE
AQVLTKFASTVHWITPKDPHTLDGHADELLAHPSVKLWEKTRLIRIKGEEAGVTAVEVRHPGESDSQELLAEGVFVYLQG
SKPITDFVAGQVEMKPDGGVWVDEMMQTSVPGVWGIGDIRNTPFKQAVVAAGDGCIAAMAIDRFLNSRKAIKPDWAH

Sequences:

>Translated_317_residues
MEQFDFDVVIVGGGPAGCTCALYTARSELKTVILDKNPAAGALAITHKIANYPGVPGEMSGDHLLEVMRDQAVEFGTVYR
RAQVYGLDLSEPVKKVYTPEGIFTGRALVLATGAMGRIASIPGEAEYLGRGVSYCATCDGAFYRNREVVVVGLNPEAVEE
AQVLTKFASTVHWITPKDPHTLDGHADELLAHPSVKLWEKTRLIRIKGEEAGVTAVEVRHPGESDSQELLAEGVFVYLQG
SKPITDFVAGQVEMKPDGGVWVDEMMQTSVPGVWGIGDIRNTPFKQAVVAAGDGCIAAMAIDRFLNSRKAIKPDWAH
>Mature_317_residues
MEQFDFDVVIVGGGPAGCTCALYTARSELKTVILDKNPAAGALAITHKIANYPGVPGEMSGDHLLEVMRDQAVEFGTVYR
RAQVYGLDLSEPVKKVYTPEGIFTGRALVLATGAMGRIASIPGEAEYLGRGVSYCATCDGAFYRNREVVVVGLNPEAVEE
AQVLTKFASTVHWITPKDPHTLDGHADELLAHPSVKLWEKTRLIRIKGEEAGVTAVEVRHPGESDSQELLAEGVFVYLQG
SKPITDFVAGQVEMKPDGGVWVDEMMQTSVPGVWGIGDIRNTPFKQAVVAAGDGCIAAMAIDRFLNSRKAIKPDWAH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=36.2459546925566, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=28.8461538461538, Blast_Score=108, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=34.6031746031746, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=33.8607594936709, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34182; Mature: 34182

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQFDFDVVIVGGGPAGCTCALYTARSELKTVILDKNPAAGALAITHKIANYPGVPGEMS
CCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHCCCCCCCCCC
GDHLLEVMRDQAVEFGTVYRRAQVYGLDLSEPVKKVYTPEGIFTGRALVLATGAMGRIAS
HHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHC
IPGEAEYLGRGVSYCATCDGAFYRNREVVVVGLNPEAVEEAQVLTKFASTVHWITPKDPH
CCCCHHHHHCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEECCCCCC
TLDGHADELLAHPSVKLWEKTRLIRIKGEEAGVTAVEVRHPGESDSQELLAEGVFVYLQG
CCCCCHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHCCEEEEEEC
SKPITDFVAGQVEMKPDGGVWVDEMMQTSVPGVWGIGDIRNTPFKQAVVAAGDGCIAAMA
CCCHHHHHCCEEEECCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHEECCCCHHHHHH
IDRFLNSRKAIKPDWAH
HHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEQFDFDVVIVGGGPAGCTCALYTARSELKTVILDKNPAAGALAITHKIANYPGVPGEMS
CCCCCEEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHCCCCCCCCCC
GDHLLEVMRDQAVEFGTVYRRAQVYGLDLSEPVKKVYTPEGIFTGRALVLATGAMGRIAS
HHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHC
IPGEAEYLGRGVSYCATCDGAFYRNREVVVVGLNPEAVEEAQVLTKFASTVHWITPKDPH
CCCCHHHHHCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEECCCCCC
TLDGHADELLAHPSVKLWEKTRLIRIKGEEAGVTAVEVRHPGESDSQELLAEGVFVYLQG
CCCCCHHHHHCCCCCEEECCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHCCEEEEEEC
SKPITDFVAGQVEMKPDGGVWVDEMMQTSVPGVWGIGDIRNTPFKQAVVAAGDGCIAAMA
CCCHHHHHCCEEEECCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHEECCCCHHHHHH
IDRFLNSRKAIKPDWAH
HHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]