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The map label for this gene is xer [C]

Identifier: 37520018

GI number: 37520018

Start: 477154

End: 478002

Strand: Reverse

Name: xer [C]

Synonym: gvip047

Alternate gene names: 37520018

Gene position: 478002-477154 (Counterclockwise)

Preceding gene: 37520019

Following gene: 37520013

Centisome position: 10.26

GC content: 66.55

Gene sequence:

>849_bases
GTGAGTTGCCTCGACGACTTTTGGGATTATCTGGAGCGCGAGCGTCGGCTGCAGCCTGCCACCTGCCGGGCCTACCGCTG
CGATCTCAAGCAATGGTTCGGCTATCTCCAAACGGCCAATCCCCTCGCAGCGCGGCCGGAGCAGTTGCGAAGCTATCTTG
TCCAGCTTGGCGAGCGGGGGATCGGCCACGGCACGTTGCGTCGCAAGCGCAGCAGCCTGCGGGTGTTCTATGGGTATTTG
CACCGGCAGGGCGTCATCGCTGCCGATCCGGCGGCGGCTTTGCCCACAGAGACCTCGCGTGTGCCCGGGCCGCCGCCGTT
GCGCCCGCAGCAATTGGAAGCCCTGCTGGGTGCGGTGGGCGATGACGCCTGCGGTGTATGCCATCGGGCCTTGATCCTGG
CCCTGTATGCGGGTGGATTGCGTTCGGCGGAGGTGAGTGCAGCCAACCTGGAGAACCTGGACTGGGAGCGCGGGCTGTGG
CGGCTGCCGCAGCGCGACGTCCTGCTGGATCCGCGCTTGTATGCCGCCCTCCTCGACTACCTTCGGTGTGGCAGGCCAGG
TTTGGCGGCCGGCATTGCCGAGCGGGCTTTGTTTGTCTCTCGGCGCGGCCATCGGTTGAGCGTGCGTGCCCTGCAGGCAT
ACCTGTCCCGCTACGGAGTCACTGCACAGCAGCTGCGCAACAGCTACGCCGCCCACCTGCTGGAGGGGGGAACCGATCCG
GTAGACGTGCAGGCGCTGCTAGGCCTGCGCTCGACTCAGGCCGCTGCAGGCCGACAACCCACCGTCGCCCAAGGCCTTCG
GCGCGTCTACGATCTGGCCCATCCGCGCAGCGGTCTGCACAAAAAATAA

Upstream 100 bases:

>100_bases
TCGCCGCATTCTGGGAGGAGAAAGGCTGATCAGCGACAGCGACAACGTCAAGCAGCACAGCCACACCCACAAAACGCTGG
TTTGAGCAGATGGGGCGGGC

Downstream 100 bases:

>100_bases
CCGACTCAGAGGCCCGTTCTTGAAAACAAAAACGGGCCTCGGCCATAGATTGTGAACTCTAGGCGGTGTGAATCAACCGA
AGCGGCCGGAAATGTAATCT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MSCLDDFWDYLERERRLQPATCRAYRCDLKQWFGYLQTANPLAARPEQLRSYLVQLGERGIGHGTLRRKRSSLRVFYGYL
HRQGVIAADPAAALPTETSRVPGPPPLRPQQLEALLGAVGDDACGVCHRALILALYAGGLRSAEVSAANLENLDWERGLW
RLPQRDVLLDPRLYAALLDYLRCGRPGLAAGIAERALFVSRRGHRLSVRALQAYLSRYGVTAQQLRNSYAAHLLEGGTDP
VDVQALLGLRSTQAAAGRQPTVAQGLRRVYDLAHPRSGLHKK

Sequences:

>Translated_282_residues
MSCLDDFWDYLERERRLQPATCRAYRCDLKQWFGYLQTANPLAARPEQLRSYLVQLGERGIGHGTLRRKRSSLRVFYGYL
HRQGVIAADPAAALPTETSRVPGPPPLRPQQLEALLGAVGDDACGVCHRALILALYAGGLRSAEVSAANLENLDWERGLW
RLPQRDVLLDPRLYAALLDYLRCGRPGLAAGIAERALFVSRRGHRLSVRALQAYLSRYGVTAQQLRNSYAAHLLEGGTDP
VDVQALLGLRSTQAAAGRQPTVAQGLRRVYDLAHPRSGLHKK
>Mature_281_residues
SCLDDFWDYLERERRLQPATCRAYRCDLKQWFGYLQTANPLAARPEQLRSYLVQLGERGIGHGTLRRKRSSLRVFYGYLH
RQGVIAADPAAALPTETSRVPGPPPLRPQQLEALLGAVGDDACGVCHRALILALYAGGLRSAEVSAANLENLDWERGLWR
LPQRDVLLDPRLYAALLDYLRCGRPGLAAGIAERALFVSRRGHRLSVRALQAYLSRYGVTAQQLRNSYAAHLLEGGTDPV
DVQALLGLRSTQAAAGRQPTVAQGLRRVYDLAHPRSGLHKK

Specific function: Potential site-specific tyrosine recombinase, which may act by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregatio

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=27.8350515463918, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=27.5510204081633, Blast_Score=89, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 31313; Mature: 31182

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCLDDFWDYLERERRLQPATCRAYRCDLKQWFGYLQTANPLAARPEQLRSYLVQLGERG
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
IGHGTLRRKRSSLRVFYGYLHRQGVIAADPAAALPTETSRVPGPPPLRPQQLEALLGAVG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
DDACGVCHRALILALYAGGLRSAEVSAANLENLDWERGLWRLPQRDVLLDPRLYAALLDY
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEECHHHHHHHHHH
LRCGRPGLAAGIAERALFVSRRGHRLSVRALQAYLSRYGVTAQQLRNSYAAHLLEGGTDP
HHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
VDVQALLGLRSTQAAAGRQPTVAQGLRRVYDLAHPRSGLHKK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SCLDDFWDYLERERRLQPATCRAYRCDLKQWFGYLQTANPLAARPEQLRSYLVQLGERG
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
IGHGTLRRKRSSLRVFYGYLHRQGVIAADPAAALPTETSRVPGPPPLRPQQLEALLGAVG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCC
DDACGVCHRALILALYAGGLRSAEVSAANLENLDWERGLWRLPQRDVLLDPRLYAALLDY
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCEECHHHHHHHHHH
LRCGRPGLAAGIAERALFVSRRGHRLSVRALQAYLSRYGVTAQQLRNSYAAHLLEGGTDP
HHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
VDVQALLGLRSTQAAAGRQPTVAQGLRRVYDLAHPRSGLHKK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]