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The map label for this gene is map [C]

Identifier: 37519981

GI number: 37519981

Start: 431172

End: 431939

Strand: Direct

Name: map [C]

Synonym: glr0412

Alternate gene names: 37519981

Gene position: 431172-431939 (Clockwise)

Preceding gene: 37519980

Following gene: 37519982

Centisome position: 9.25

GC content: 63.67

Gene sequence:

>768_bases
ATGGCCCTGCTTGAGATCAAGTCCACCCGCGAGATCGCCAAGATGCGCGAAGCTGGCCGGATTGTGGCAACGGTTCTCAA
AGAAATCATGGCCCTAGCCGAACCGGGCCTGACCACCGGCGATCTCGACGCCCACGCCGAGCGCCGCTGCGCCGATTTTG
GCGTCATCCCCGCCTTCAAGGGTTATCACGGTTTTCCCGCCTGCATCTGCACGTCGATCAACCACGAGGTCGTCCACGGC
ATTCCGAGCGCCAAGCGTCGGCTCAAACCCGGCGATGTCCTCAAAGTCGACTTTGGGGCCATCTACGACGGCTGGCACGG
CGATTCGTGCGTGACCATCGGTCTTGAGCCGCTTGCCGAGGAGGCCCGCACACTGATCCGGGTGGCCGAGGAGGCCCTGC
TCAAGGGCATCCGCGAGGTGCGCCAGGGCGTGCATCTGCAGCAAGTCTCCGGGGCCATCCAGGACTACGTCGAAGGCTAC
GGCTTCTCGGTGGTACGCCAGTACGTCGGCCACGGCGTCGGGCGCAACCTGCACGAGGAGCCCCAGGTGCCCAACTTTCG
CACCCGGGAGATTCCCGATCCCAAGCTCAAGTCGGGTATGACCCTGGCCATCGAACCGATGGTCAACCTCGGCCACCACG
CCACCCGCACGCTGGCCGATCGCTGGACGGTGGTCACCCTCGACAATTCGCTCTCAGCCCAGTTCGAACACACAGTTCTG
GTCACCCGAGACGGCTACGAGATTCTTACCGACCGTTCGAAGGTCTGA

Upstream 100 bases:

>100_bases
CCAGCGGAGCGGGCGGGTGCGGGCGGCGGCGGCTAGGTACGAAGTTCTGCAATAATATTAATGATAGCGATGCTGTGTTT
ACAGTCGATGAAGGAAAGCC

Downstream 100 bases:

>100_bases
CCTTTATTCAGGAGTTGTCCTTGGCAAAGCAAGACGTCATTGAGATGGAAGGAACCGTTGTCGAGTCGCTCCCCAACGCC
ATGTTTCGGGTCGAACTCGA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MALLEIKSTREIAKMREAGRIVATVLKEIMALAEPGLTTGDLDAHAERRCADFGVIPAFKGYHGFPACICTSINHEVVHG
IPSAKRRLKPGDVLKVDFGAIYDGWHGDSCVTIGLEPLAEEARTLIRVAEEALLKGIREVRQGVHLQQVSGAIQDYVEGY
GFSVVRQYVGHGVGRNLHEEPQVPNFRTREIPDPKLKSGMTLAIEPMVNLGHHATRTLADRWTVVTLDNSLSAQFEHTVL
VTRDGYEILTDRSKV

Sequences:

>Translated_255_residues
MALLEIKSTREIAKMREAGRIVATVLKEIMALAEPGLTTGDLDAHAERRCADFGVIPAFKGYHGFPACICTSINHEVVHG
IPSAKRRLKPGDVLKVDFGAIYDGWHGDSCVTIGLEPLAEEARTLIRVAEEALLKGIREVRQGVHLQQVSGAIQDYVEGY
GFSVVRQYVGHGVGRNLHEEPQVPNFRTREIPDPKLKSGMTLAIEPMVNLGHHATRTLADRWTVVTLDNSLSAQFEHTVL
VTRDGYEILTDRSKV
>Mature_254_residues
ALLEIKSTREIAKMREAGRIVATVLKEIMALAEPGLTTGDLDAHAERRCADFGVIPAFKGYHGFPACICTSINHEVVHGI
PSAKRRLKPGDVLKVDFGAIYDGWHGDSCVTIGLEPLAEEARTLIRVAEEALLKGIREVRQGVHLQQVSGAIQDYVEGYG
FSVVRQYVGHGVGRNLHEEPQVPNFRTREIPDPKLKSGMTLAIEPMVNLGHHATRTLADRWTVVTLDNSLSAQFEHTVLV
TRDGYEILTDRSKV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=36.9477911646586, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=34.0080971659919, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=46.4566929133858, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1788728, Length=255, Percent_Identity=27.4509803921569, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71996291, Length=256, Percent_Identity=36.328125, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6323273, Length=252, Percent_Identity=36.9047619047619, Blast_Score=162, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=37.3983739837398, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21355531, Length=254, Percent_Identity=38.5826771653543, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28126; Mature: 27994

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLEIKSTREIAKMREAGRIVATVLKEIMALAEPGLTTGDLDAHAERRCADFGVIPAFK
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
GYHGFPACICTSINHEVVHGIPSAKRRLKPGDVLKVDFGAIYDGWHGDSCVTIGLEPLAE
CCCCCHHHHHHCCCHHHHHCCCHHHHCCCCCCEEEEECCCEECCCCCCCEEEECCHHHHH
EARTLIRVAEEALLKGIREVRQGVHLQQVSGAIQDYVEGYGFSVVRQYVGHGVGRNLHEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
PQVPNFRTREIPDPKLKSGMTLAIEPMVNLGHHATRTLADRWTVVTLDNSLSAQFEHTVL
CCCCCCCCCCCCCHHHHCCCEEEEEHHHHCCHHHHHHHHHCEEEEEECCCCCCCEEEEEE
VTRDGYEILTDRSKV
EEECCHHHHCCCCCC
>Mature Secondary Structure 
ALLEIKSTREIAKMREAGRIVATVLKEIMALAEPGLTTGDLDAHAERRCADFGVIPAFK
CEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCC
GYHGFPACICTSINHEVVHGIPSAKRRLKPGDVLKVDFGAIYDGWHGDSCVTIGLEPLAE
CCCCCHHHHHHCCCHHHHHCCCHHHHCCCCCCEEEEECCCEECCCCCCCEEEECCHHHHH
EARTLIRVAEEALLKGIREVRQGVHLQQVSGAIQDYVEGYGFSVVRQYVGHGVGRNLHEE
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCC
PQVPNFRTREIPDPKLKSGMTLAIEPMVNLGHHATRTLADRWTVVTLDNSLSAQFEHTVL
CCCCCCCCCCCCCHHHHCCCEEEEEHHHHCCHHHHHHHHHCEEEEEECCCCCCCEEEEEE
VTRDGYEILTDRSKV
EEECCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]