Click here to switch to the map view.

The map label for this gene is cobO [H]

Identifier: 37519954

GI number: 37519954

Start: 406192

End: 406854

Strand: Direct

Name: cobO [H]

Synonym: gvip031

Alternate gene names: 37519954

Gene position: 406192-406854 (Clockwise)

Preceding gene: 37519951

Following gene: 37519955

Centisome position: 8.72

GC content: 62.44

Gene sequence:

>663_bases
ATGATCCCACGACCGCCCGATTGGTGGCACGATGGCCTGGTAGCGCGAGGCCCGACCATGACCGATGCCGACACCGCCCA
CAAACTCAAAATGGAGCGCCGCAAGCAGGTGCAGGAGCAGCGCCTGGCCGAGCGCGACCGCAAAAAGGGACTGCTCATCG
TCTACACCGGTGACGGCAAGGGCAAAAGTTCGGCGGCCTTCGGCATGATCTTCCGTTCACTGGGCCACGGCCTGCCGGTG
GCGGTGATCCAGTTCATCAAGGGTGCCTGGGAACCGGGAGAAGCCAAACTGCTCGGCCGCTTCCCGGAGCTGGTAGTCTT
TCGGGCGATGGGCGAAGGGTTTACCTGGGAGACCCAGGATCGCGGGCGCGATATCGCCAAAGCGGGTGAAGCCTGGGAGG
CGGGACTGGAACTTATCCTGGCGGGCCGACACCACATCGTGCTGCTCGATGAAATCAACGTGGCGATGAAACTGGGATAT
CTCGATCCCAATCAAGTCCTGGCGGGCCTGGCGCGCAAGCCCGAGATGGTCCATGTCGTGCTCACCGGCCGCGGCGCCCC
GGAGAGCATCATCGAAGCCGCCGATTTGGTGACGGAGATGAAACTGGTCAAACACCCCTTCCGCAGCCAGGGGATCAAAG
CGCAGCTGGGAATAGAGTATTGA

Upstream 100 bases:

>100_bases
ACGATCTGATATTCGGCGGGTGGGAAGGCGTGCTCGCCGATTTCAGCATCGATGATGGCGAAACTTTCGGCGGTGATTGG
GTGAAGGTCCATGCCTTCTA

Downstream 100 bases:

>100_bases
GCCAGTACACGACCTTGCGATGGTCAGACCCGCCGTGCCTGTCAGTGTCATCTCCAAAAACGGTGTCCCTATTCGGCTGA
CGGAGGAGCGATGGGAGCAT

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MIPRPPDWWHDGLVARGPTMTDADTAHKLKMERRKQVQEQRLAERDRKKGLLIVYTGDGKGKSSAAFGMIFRSLGHGLPV
AVIQFIKGAWEPGEAKLLGRFPELVVFRAMGEGFTWETQDRGRDIAKAGEAWEAGLELILAGRHHIVLLDEINVAMKLGY
LDPNQVLAGLARKPEMVHVVLTGRGAPESIIEAADLVTEMKLVKHPFRSQGIKAQLGIEY

Sequences:

>Translated_220_residues
MIPRPPDWWHDGLVARGPTMTDADTAHKLKMERRKQVQEQRLAERDRKKGLLIVYTGDGKGKSSAAFGMIFRSLGHGLPV
AVIQFIKGAWEPGEAKLLGRFPELVVFRAMGEGFTWETQDRGRDIAKAGEAWEAGLELILAGRHHIVLLDEINVAMKLGY
LDPNQVLAGLARKPEMVHVVLTGRGAPESIIEAADLVTEMKLVKHPFRSQGIKAQLGIEY
>Mature_220_residues
MIPRPPDWWHDGLVARGPTMTDADTAHKLKMERRKQVQEQRLAERDRKKGLLIVYTGDGKGKSSAAFGMIFRSLGHGLPV
AVIQFIKGAWEPGEAKLLGRFPELVVFRAMGEGFTWETQDRGRDIAKAGEAWEAGLELILAGRHHIVLLDEINVAMKLGY
LDPNQVLAGLARKPEMVHVVLTGRGAPESIIEAADLVTEMKLVKHPFRSQGIKAQLGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=198, Percent_Identity=40.9090909090909, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 24421; Mature: 24421

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPRPPDWWHDGLVARGPTMTDADTAHKLKMERRKQVQEQRLAERDRKKGLLIVYTGDGK
CCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GKSSAAFGMIFRSLGHGLPVAVIQFIKGAWEPGEAKLLGRFPELVVFRAMGEGFTWETQD
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCHH
RGRDIAKAGEAWEAGLELILAGRHHIVLLDEINVAMKLGYLDPNQVLAGLARKPEMVHVV
HCCHHHHHCHHHHHHHHEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEE
LTGRGAPESIIEAADLVTEMKLVKHPFRSQGIKAQLGIEY
EECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCC
>Mature Secondary Structure
MIPRPPDWWHDGLVARGPTMTDADTAHKLKMERRKQVQEQRLAERDRKKGLLIVYTGDGK
CCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
GKSSAAFGMIFRSLGHGLPVAVIQFIKGAWEPGEAKLLGRFPELVVFRAMGEGFTWETQD
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCCCCCCCHH
RGRDIAKAGEAWEAGLELILAGRHHIVLLDEINVAMKLGYLDPNQVLAGLARKPEMVHVV
HCCHHHHHCHHHHHHHHEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEE
LTGRGAPESIIEAADLVTEMKLVKHPFRSQGIKAQLGIEY
EECCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]