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The map label for this gene is prpC [H]

Identifier: 37519727

GI number: 37519727

Start: 150634

End: 152166

Strand: Reverse

Name: prpC [H]

Synonym: gll0158

Alternate gene names: 37519727

Gene position: 152166-150634 (Counterclockwise)

Preceding gene: 37519728

Following gene: 37519726

Centisome position: 3.27

GC content: 64.25

Gene sequence:

>1533_bases
GTGAGCCTTTCGAGCCCAAAATCTCGCTTATTAAATAGACCCTCGAACTGCCTGCCGTCTGGAGAGCCTGCGGCGGGTTG
CGCCGTGGAGTCGGGTTGCCGGACACGGACGAAGCCGCCCTATCCCACCCATCAGCACAAGATGTATTACCTTGCCACCG
AAGAGTACCAACGCCTGCCTTCCCCGCTGGCTGACCGCTACACCGTTGTCAATCGCTCTCCGCTGGTGGTGCGCGACCTT
TACCCGGAGCGCGAAAGTACACCCCCCGATGTCACGCTGGACACGGCTCAGCCTTACCAGCGCCTCAACCCATGGCGCTG
GGCGATCCCGGAGGTGCATGCCCAGTTCACCCCCGGCCGGTGCCTGTTGCTCGAAAACGCGCCGCTGGAGGAAGACGGCG
CTCCCTGGCCCACCTTGGGGCAGTCCTGGCCCATGGCGGAGCCGCTGCGGCAGTTGGGCTGGTTGTTGCAACTGGCGAAA
CTTTGGGAGCCGTGTTGTCGGCAGAAGGTCGTATCTTCGCTGCTCGCGTCGGCCAATATCGGAGTGCAGGGCTGGCAGGT
GCGCCTGTTTTATCTCACTCAAGACCGGGTGCCGGTATCTTTGCAGGCCTTGGCGGCAAGCTGGCTCTCGCTCACACCGA
TGGTGGGCGAGCTGCGCGCCGTGGTCCAAGCACTTGCAGCCGGAAAATTCGCTCGGATAGAGGTGCTGGTGGCGGCGCTG
GAAGCTCTGGCGGTACAGACGAACACCGGTTGTCGGGTGCAGGCGGTAACCAGCGCCACCCACCCGGGGCGCCGGGAGCT
GAATGAAGATTGTCTGGTCTATGATCCCCAGGGCCGCTTCGCCGTAGTCTGCGACGGCATGGGCGGACACGAAGGGGGCA
AACTGGCCAGTTTTCTGGCCATCTCTTCGCTTCAGCAGGACTTTGCCTGCTTGAGCTATCAGGATTCCCCCCCCTCCGAG
CTGCGCGCTCAACTGGCGGGTGCGGCGCAGCGGGCCCACCAGCGGCTGTGGCGGCTCAACCAGCGGCAGGGGCGCAGCGG
GCGGCGGCAGATGGGTACGACCGTGGCAGCCTGCTTTTTGAGGGGACCGTTGCTGCACACGGTGCATGTGGGCGACAGTC
GCGTCTATCTTATCGACCGGCGGCACTGCCAGCAGTTGAGCGTCGATGACGATGTGCTCAATCTGGAGGTGAGTCTGGCG
CGCACCACCCGCCGGGCGCTGCACCGGCAGTCCGGCAGCGGCAGGCTGACCCAGGCGCTTGGGGTGATTCCTCCGAACGA
CCTCAAGCCCACCACCCGGAGCTTTTTGCTTCCGGAAGATTGTCTGGTGCTGCTGTGCAGCGACGGACTCTCGGACGGCG
ACTTTGTGGAACGCCACTGGCGCGAGGCGTTTTTGCCATTGCTCGATAGGGGCAATCTCGAAGCTGCGGGCGCTGCGCTC
GTTGAAATGGCCCTTTTGGAGCTGGGGCACGACAACATCTCGTTCGTGCTGCTCAAGTACGCCGCTGCTGCGCCCCGCAC
CGATGCCGGCTGA

Upstream 100 bases:

>100_bases
ACCCTCGAAGATCGCTCGGTGCTCGAGAAGCTGCGCGAGGGCTAAAATCTGCGCGGTTGTATGAGTTATAGCGGTGGCCC
GGTGAAAAATTAACCGCATA

Downstream 100 bases:

>100_bases
CCCGCACGCTGCCGTGAAGCGCCTGTAGCTGGGGCCTTGCTGGAATAATTTCGTCCTGCAGATTCGGTGAGCTTGCCCGG
CTGCTGGTGCACTACCGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MSLSSPKSRLLNRPSNCLPSGEPAAGCAVESGCRTRTKPPYPTHQHKMYYLATEEYQRLPSPLADRYTVVNRSPLVVRDL
YPERESTPPDVTLDTAQPYQRLNPWRWAIPEVHAQFTPGRCLLLENAPLEEDGAPWPTLGQSWPMAEPLRQLGWLLQLAK
LWEPCCRQKVVSSLLASANIGVQGWQVRLFYLTQDRVPVSLQALAASWLSLTPMVGELRAVVQALAAGKFARIEVLVAAL
EALAVQTNTGCRVQAVTSATHPGRRELNEDCLVYDPQGRFAVVCDGMGGHEGGKLASFLAISSLQQDFACLSYQDSPPSE
LRAQLAGAAQRAHQRLWRLNQRQGRSGRRQMGTTVAACFLRGPLLHTVHVGDSRVYLIDRRHCQQLSVDDDVLNLEVSLA
RTTRRALHRQSGSGRLTQALGVIPPNDLKPTTRSFLLPEDCLVLLCSDGLSDGDFVERHWREAFLPLLDRGNLEAAGAAL
VEMALLELGHDNISFVLLKYAAAAPRTDAG

Sequences:

>Translated_510_residues
MSLSSPKSRLLNRPSNCLPSGEPAAGCAVESGCRTRTKPPYPTHQHKMYYLATEEYQRLPSPLADRYTVVNRSPLVVRDL
YPERESTPPDVTLDTAQPYQRLNPWRWAIPEVHAQFTPGRCLLLENAPLEEDGAPWPTLGQSWPMAEPLRQLGWLLQLAK
LWEPCCRQKVVSSLLASANIGVQGWQVRLFYLTQDRVPVSLQALAASWLSLTPMVGELRAVVQALAAGKFARIEVLVAAL
EALAVQTNTGCRVQAVTSATHPGRRELNEDCLVYDPQGRFAVVCDGMGGHEGGKLASFLAISSLQQDFACLSYQDSPPSE
LRAQLAGAAQRAHQRLWRLNQRQGRSGRRQMGTTVAACFLRGPLLHTVHVGDSRVYLIDRRHCQQLSVDDDVLNLEVSLA
RTTRRALHRQSGSGRLTQALGVIPPNDLKPTTRSFLLPEDCLVLLCSDGLSDGDFVERHWREAFLPLLDRGNLEAAGAAL
VEMALLELGHDNISFVLLKYAAAAPRTDAG
>Mature_509_residues
SLSSPKSRLLNRPSNCLPSGEPAAGCAVESGCRTRTKPPYPTHQHKMYYLATEEYQRLPSPLADRYTVVNRSPLVVRDLY
PERESTPPDVTLDTAQPYQRLNPWRWAIPEVHAQFTPGRCLLLENAPLEEDGAPWPTLGQSWPMAEPLRQLGWLLQLAKL
WEPCCRQKVVSSLLASANIGVQGWQVRLFYLTQDRVPVSLQALAASWLSLTPMVGELRAVVQALAAGKFARIEVLVAALE
ALAVQTNTGCRVQAVTSATHPGRRELNEDCLVYDPQGRFAVVCDGMGGHEGGKLASFLAISSLQQDFACLSYQDSPPSEL
RAQLAGAAQRAHQRLWRLNQRQGRSGRRQMGTTVAACFLRGPLLHTVHVGDSRVYLIDRRHCQQLSVDDDVLNLEVSLAR
TTRRALHRQSGSGRLTQALGVIPPNDLKPTTRSFLLPEDCLVLLCSDGLSDGDFVERHWREAFLPLLDRGNLEAAGAALV
EMALLELGHDNISFVLLKYAAAAPRTDAG

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 56251; Mature: 56120

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSPKSRLLNRPSNCLPSGEPAAGCAVESGCRTRTKPPYPTHQHKMYYLATEEYQRLP
CCCCCCHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHCC
SPLADRYTVVNRSPLVVRDLYPERESTPPDVTLDTAQPYQRLNPWRWAIPEVHAQFTPGR
CCHHHCEEEECCCCEEEEECCCCCCCCCCCEEECCCCHHHHCCCCEECCCHHHCCCCCCE
CLLLENAPLEEDGAPWPTLGQSWPMAEPLRQLGWLLQLAKLWEPCCRQKVVSSLLASANI
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVQGWQVRLFYLTQDRVPVSLQALAASWLSLTPMVGELRAVVQALAAGKFARIEVLVAAL
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EALAVQTNTGCRVQAVTSATHPGRRELNEDCLVYDPQGRFAVVCDGMGGHEGGKLASFLA
HHHHEECCCCCEEEEECCCCCCCHHHCCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHH
ISSLQQDFACLSYQDSPPSELRAQLAGAAQRAHQRLWRLNQRQGRSGRRQMGTTVAACFL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGPLLHTVHVGDSRVYLIDRRHCQQLSVDDDVLNLEVSLARTTRRALHRQSGSGRLTQAL
CCCCEEEEEECCCEEEEEECHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHH
GVIPPNDLKPTTRSFLLPEDCLVLLCSDGLSDGDFVERHWREAFLPLLDRGNLEAAGAAL
CCCCCCCCCCCHHHHCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
VEMALLELGHDNISFVLLKYAAAAPRTDAG
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLSSPKSRLLNRPSNCLPSGEPAAGCAVESGCRTRTKPPYPTHQHKMYYLATEEYQRLP
CCCCCHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHCC
SPLADRYTVVNRSPLVVRDLYPERESTPPDVTLDTAQPYQRLNPWRWAIPEVHAQFTPGR
CCHHHCEEEECCCCEEEEECCCCCCCCCCCEEECCCCHHHHCCCCEECCCHHHCCCCCCE
CLLLENAPLEEDGAPWPTLGQSWPMAEPLRQLGWLLQLAKLWEPCCRQKVVSSLLASANI
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVQGWQVRLFYLTQDRVPVSLQALAASWLSLTPMVGELRAVVQALAAGKFARIEVLVAAL
CCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EALAVQTNTGCRVQAVTSATHPGRRELNEDCLVYDPQGRFAVVCDGMGGHEGGKLASFLA
HHHHEECCCCCEEEEECCCCCCCHHHCCCCCEEECCCCCEEEEECCCCCCCCCHHHHHHH
ISSLQQDFACLSYQDSPPSELRAQLAGAAQRAHQRLWRLNQRQGRSGRRQMGTTVAACFL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RGPLLHTVHVGDSRVYLIDRRHCQQLSVDDDVLNLEVSLARTTRRALHRQSGSGRLTQAL
CCCCEEEEEECCCEEEEEECHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCHHHHH
GVIPPNDLKPTTRSFLLPEDCLVLLCSDGLSDGDFVERHWREAFLPLLDRGNLEAAGAAL
CCCCCCCCCCCHHHHCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
VEMALLELGHDNISFVLLKYAAAAPRTDAG
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]