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The map label for this gene is rnpA

Identifier: 34499861

GI number: 34499861

Start: 4750490

End: 4750855

Strand: Reverse

Name: rnpA

Synonym: CV_4406

Alternate gene names: 34499861

Gene position: 4750855-4750490 (Counterclockwise)

Preceding gene: 34499862

Following gene: 34499860

Centisome position: 100.0

GC content: 62.02

Gene sequence:

>366_bases
TTGTCGGCTTACCGCTTTCGCCGTGCGCACCGGCTGTTAAAAACGGATGAGTTCTCATCCGTTTTTAGTTTGCGGCAGCA
GCGCAGCAATGCGTTCTTCCAGGTGTTCGCCCGTCCCAACGGCCTGGACCACGCCCGCGTGGGCTTGGTGGTCGGCAAGA
AGGTCGCCAAGCGGGCGGTACGCCGCAATTACATCAAGCGCTGCGTGCGCGAGTGGTTCCGCCTGAACCAGCAAGGCCTG
GACGGCGTGGACTACGTGGTGCGCGCCAAGACGGCGTTTACCCGCGAGCAGCGCGCCGAAGCTGTAACGGCGTTGCAGGC
GTTGTTTGCTAAACTGGCACGATGTCGCGCATCCTCATCCTCCTGA

Upstream 100 bases:

>100_bases
CGCACTCACGGCTTTCTGGTCCGCATGAAGACCCGCGGCGGCCGCGCCGTCATCGCCGCTCGCCGCGCCAAGGGCCGCAA
GCGTCTGGCCGTCTAAGCCC

Downstream 100 bases:

>100_bases
TCCGTTTCTACCAGCTGGCTATCAGCCCGTGGTTGGCGCCGCGTTGCCGCTTCCAGCCCACCTGTTCCGGCTACGCGATC
GAGGCGGTGAGTAAACACGG

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSAYRFRRAHRLLKTDEFSSVFSLRQQRSNAFFQVFARPNGLDHARVGLVVGKKVAKRAVRRNYIKRCVREWFRLNQQGL
DGVDYVVRAKTAFTREQRAEAVTALQALFAKLARCRASSSS

Sequences:

>Translated_121_residues
MSAYRFRRAHRLLKTDEFSSVFSLRQQRSNAFFQVFARPNGLDHARVGLVVGKKVAKRAVRRNYIKRCVREWFRLNQQGL
DGVDYVVRAKTAFTREQRAEAVTALQALFAKLARCRASSSS
>Mature_120_residues
SAYRFRRAHRLLKTDEFSSVFSLRQQRSNAFFQVFARPNGLDHARVGLVVGKKVAKRAVRRNYIKRCVREWFRLNQQGLD
GVDYVVRAKTAFTREQRAEAVTALQALFAKLARCRASSSS

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=121, Percent_Identity=37.1900826446281, Blast_Score=69, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_CHRVO (Q7NPT6)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_904076.1
- ProteinModelPortal:   Q7NPT6
- SMR:   Q7NPT6
- GeneID:   2549648
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_4406
- NMPDR:   fig|243365.1.peg.4406
- HOGENOM:   HBG728160
- OMA:   NPATGCR
- PhylomeDB:   Q7NPT6
- ProtClustDB:   PRK04390
- BioCyc:   CVIO243365:CV_4406-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13967; Mature: 13836

Theoretical pI: Translated: 12.09; Mature: 12.09

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAYRFRRAHRLLKTDEFSSVFSLRQQRSNAFFQVFARPNGLDHARVGLVVGKKVAKRAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RRNYIKRCVREWFRLNQQGLDGVDYVVRAKTAFTREQRAEAVTALQALFAKLARCRASSS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
S
C
>Mature Secondary Structure 
SAYRFRRAHRLLKTDEFSSVFSLRQQRSNAFFQVFARPNGLDHARVGLVVGKKVAKRAV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
RRNYIKRCVREWFRLNQQGLDGVDYVVRAKTAFTREQRAEAVTALQALFAKLARCRASSS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782