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The map label for this gene is macB [H]

Identifier: 34499851

GI number: 34499851

Start: 4739695

End: 4740918

Strand: Reverse

Name: macB [H]

Synonym: CV_4396

Alternate gene names: 34499851

Gene position: 4740918-4739695 (Counterclockwise)

Preceding gene: 34499852

Following gene: 34499840

Centisome position: 99.79

GC content: 70.59

Gene sequence:

>1224_bases
ATGCTGCTCGAATGCTGGCGCAACGGCTGGCGCAGCCTGCGCGGCCATCCGATGCGCAGCCTGCTCAGCGCGCTGGGCAT
CGTCATCGGCGTCGCCGCGGTGATCGCCGTGATCGCGATCGTGCAGGGGCTGTCGCGCTCGGTCAGCGAGAATTTCGACC
GCCTGGGCGCCAACAGCCTGAGCGTGGAGGCCAAGACCGAGCTGGAGGAGGCGCTGCAGGGGCGGCGCAATCGCCTGGGC
TGGGCCGATTACCGGCAGATCTTGCGGCAGGAGGGCGGCACGGCGGCGCTGGCGGCGTCGTTCGCGCCGTTCGGCGACTA
CGGCGCGACTGTCCGCTACGGCCGCCGCACCGCCTTCGCGGCGGTCAACGCGGTCACCGCTTCCTACCAGACGGTGCAGC
AGGCCTTCGTGCGGGAGGGGCGCTTCATCCGCAACAGTGACGACCGCTCCCGGCGCAAGGTGTGCGTGATAGGCAGCGAT
CTGGCGGCCAAGCTCAAGCTGCCGGAGAGGCCGGAGGGCGAGTTCGTCGAGGTGTCGGGCGAGTGGTACAAGATCATAGG
CGTGATGGAGTCGCGCGGCGCGGTCTTCGGCGTCAGCAGCGACAACTATCTGCTGATACCGTTTTCCGCCGGCCAGGCCG
CGCTGGCCGCCGGCAACCCGCCCGATTTGTCGATCGCGCTGAACGTCGCCGATCCGGCGGCGCTGGAGCCGGTGCGGCAA
CGCCTGCGCGCGCTGCTGCGCCGGCTGCACCGGCTGGGGCCGGGCCAGGCCGACGACTTTCGCATTCAGAGCGCCCGCCA
ACTGAGCGAGGCCTTCCACGCCATCGTCGACGGCATGAGCCTGGGCCTGGCCGGCATCGTCGGCATCTCGCTGCTGGTGG
GCGGGATAGGCATCATGAACGTCATGCTGGTGTCGGTGACCGAGCGGACGCGCGAGATCGGCCTGCTGAAGGCGCTGGGC
GCCCGGCGCGCGCACATTCTGCTGCAATTCCTGTCCGAGTCGGTCTGCCTGTCGCTGGCCGGCGGGGCGGCCGGCGTGTT
GGGCGGCTATCTGCTGGCCGGCGCGTTCTCGCTGCTGGTGCCGGCACTGCCGGCGCCGGCGGTGCCGTGGTGGGCGGTCG
CGCTGGCACTGGGCTTCACCGTCACCGTCGGCTTGGTGTTCGGCCTGGCACCGGCGGTCAAGGCGGCCAATCTGGAGCCG
GTGGAGGCGCTGCGCTATGAATAG

Upstream 100 bases:

>100_bases
TCCTGGTGACGCATTCGGACGAGATCGCCGCCCGCTGCCGGCGGCGGATACGGATGGCCGACGGCCGTCTGGTCGCGGAC
AGCGGGGAGGCGGCATGACG

Downstream 100 bases:

>100_bases
CGCGGCGGCGCACTTGTCCACAGCGCGTCCCGCCGGCGATTTTTATCCACAGGCCGCTCAGCCGCGCTGCGACGGACTCA
GCCAGTCTCCGAGCCATTGA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLLECWRNGWRSLRGHPMRSLLSALGIVIGVAAVIAVIAIVQGLSRSVSENFDRLGANSLSVEAKTELEEALQGRRNRLG
WADYRQILRQEGGTAALAASFAPFGDYGATVRYGRRTAFAAVNAVTASYQTVQQAFVREGRFIRNSDDRSRRKVCVIGSD
LAAKLKLPERPEGEFVEVSGEWYKIIGVMESRGAVFGVSSDNYLLIPFSAGQAALAAGNPPDLSIALNVADPAALEPVRQ
RLRALLRRLHRLGPGQADDFRIQSARQLSEAFHAIVDGMSLGLAGIVGISLLVGGIGIMNVMLVSVTERTREIGLLKALG
ARRAHILLQFLSESVCLSLAGGAAGVLGGYLLAGAFSLLVPALPAPAVPWWAVALALGFTVTVGLVFGLAPAVKAANLEP
VEALRYE

Sequences:

>Translated_407_residues
MLLECWRNGWRSLRGHPMRSLLSALGIVIGVAAVIAVIAIVQGLSRSVSENFDRLGANSLSVEAKTELEEALQGRRNRLG
WADYRQILRQEGGTAALAASFAPFGDYGATVRYGRRTAFAAVNAVTASYQTVQQAFVREGRFIRNSDDRSRRKVCVIGSD
LAAKLKLPERPEGEFVEVSGEWYKIIGVMESRGAVFGVSSDNYLLIPFSAGQAALAAGNPPDLSIALNVADPAALEPVRQ
RLRALLRRLHRLGPGQADDFRIQSARQLSEAFHAIVDGMSLGLAGIVGISLLVGGIGIMNVMLVSVTERTREIGLLKALG
ARRAHILLQFLSESVCLSLAGGAAGVLGGYLLAGAFSLLVPALPAPAVPWWAVALALGFTVTVGLVFGLAPAVKAANLEP
VEALRYE
>Mature_407_residues
MLLECWRNGWRSLRGHPMRSLLSALGIVIGVAAVIAVIAIVQGLSRSVSENFDRLGANSLSVEAKTELEEALQGRRNRLG
WADYRQILRQEGGTAALAASFAPFGDYGATVRYGRRTAFAAVNAVTASYQTVQQAFVREGRFIRNSDDRSRRKVCVIGSD
LAAKLKLPERPEGEFVEVSGEWYKIIGVMESRGAVFGVSSDNYLLIPFSAGQAALAAGNPPDLSIALNVADPAALEPVRQ
RLRALLRRLHRLGPGQADDFRIQSARQLSEAFHAIVDGMSLGLAGIVGISLLVGGIGIMNVMLVSVTERTREIGLLKALG
ARRAHILLQFLSESVCLSLAGGAAGVLGGYLLAGAFSLLVPALPAPAVPWWAVALALGFTVTVGLVFGLAPAVKAANLEP
VEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=406, Percent_Identity=30.7881773399015, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43364; Mature: 43364

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00213 LIPOCALIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLECWRNGWRSLRGHPMRSLLSALGIVIGVAAVIAVIAIVQGLSRSVSENFDRLGANSL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVEAKTELEEALQGRRNRLGWADYRQILRQEGGTAALAASFAPFGDYGATVRYGRRTAFA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCHHHHCCHHHHH
AVNAVTASYQTVQQAFVREGRFIRNSDDRSRRKVCVIGSDLAAKLKLPERPEGEFVEVSG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCEEEECC
EWYKIIGVMESRGAVFGVSSDNYLLIPFSAGQAALAAGNPPDLSIALNVADPAALEPVRQ
CEEEEEEEECCCCCEEEECCCCEEEEEECCCCEEECCCCCCCEEEEEECCCCHHHHHHHH
RLRALLRRLHRLGPGQADDFRIQSARQLSEAFHAIVDGMSLGLAGIVGISLLVGGIGIMN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMLVSVTERTREIGLLKALGARRAHILLQFLSESVCLSLAGGAAGVLGGYLLAGAFSLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
PALPAPAVPWWAVALALGFTVTVGLVFGLAPAVKAANLEPVEALRYE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MLLECWRNGWRSLRGHPMRSLLSALGIVIGVAAVIAVIAIVQGLSRSVSENFDRLGANSL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SVEAKTELEEALQGRRNRLGWADYRQILRQEGGTAALAASFAPFGDYGATVRYGRRTAFA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEHHHCCCCCCCCCHHHHCCHHHHH
AVNAVTASYQTVQQAFVREGRFIRNSDDRSRRKVCVIGSDLAAKLKLPERPEGEFVEVSG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHCCCCCCCCCCCEEEECC
EWYKIIGVMESRGAVFGVSSDNYLLIPFSAGQAALAAGNPPDLSIALNVADPAALEPVRQ
CEEEEEEEECCCCCEEEECCCCEEEEEECCCCEEECCCCCCCEEEEEECCCCHHHHHHHH
RLRALLRRLHRLGPGQADDFRIQSARQLSEAFHAIVDGMSLGLAGIVGISLLVGGIGIMN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMLVSVTERTREIGLLKALGARRAHILLQFLSESVCLSLAGGAAGVLGGYLLAGAFSLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
PALPAPAVPWWAVALALGFTVTVGLVFGLAPAVKAANLEPVEALRYE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA