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The map label for this gene is erg3 [H]

Identifier: 34499827

GI number: 34499827

Start: 4715406

End: 4716290

Strand: Reverse

Name: erg3 [H]

Synonym: CV_4372

Alternate gene names: 34499827

Gene position: 4716290-4715406 (Counterclockwise)

Preceding gene: 34499828

Following gene: 34499825

Centisome position: 99.27

GC content: 66.21

Gene sequence:

>885_bases
ATGAAATTTCCGGTTGAACTGATTCTGCTGGCGCTGGCGCCGGTGTTCCTGCTGTTTGTCGCCTGGGAGCTGTGGCTGTT
CCGGCGCCAGGGCCGGCTCGGCCTGTACCACTGGCGCGATTCGCTGTGCAGCGCGGCCTTGGGCCTGCTGCACCAGGGCG
CGGACAAGCTGGCCTGGGTGCTGGTGCTGCCGCTGTACGGCTGGATCTACCAGCACCACCGCCTGTTCGATTTTTCCGCT
GGCTGGCTGAGCTTCTTCCTGCTGTTCCTCGGCCAGGATTTCCTTTATTACTGGTTCCACCGCGTCAGTCACCGCGTGCG
CTGGCTGTGGGCGGCGCACAGCGTCCACCATAGCTCGACGCGGATGAATTTCACCACCGCCTTCCGCCAGAGCCTGATGT
ATCCGCTGGCCGGCATGTGGGCGTTCTGGCTGCCGCTGGCCTGGCTGGGGTTTCCGCCCGAGCAGGTGGTGGCGGTGGTG
CTGCTCAACCTGGCCTTCCAGTTCTTTGTCCATACCCAGGCCGCGCCCAAGCTGGGCTGGCTGGAATACGTGTTCAACAC
CCCGTCCATACACCGCGGCCACCACGCCAAGAACCCGCGCTACATCGACCACAACTACGCCGGCGTGCTGGTGGTCTGGG
ACCGGCTGTTCGGCACCTATGCCGAGGAGCTGGACAGCGATCCGTGCGACTACGGCACGGTGAAGCCGGTCAACAGCTTC
AACCCGCTGTGGGTCAGCCTGGTGGAGTGGCGCGACATGCTGGCGGAAGCCTGGCATGCCCGGAACTGGCGCGATCGGCT
GGTGCTGCTGTTCGGACCGCCGGAGGCGGCGGAGAAAGTGGCCGAGCGGCAGCGCGCCGGCGAGGCGAGGCGGGCGGCGG
CCTGA

Upstream 100 bases:

>100_bases
AGCGGCGCGGGAATGCGCGCGCGCGGCCTTCCGCCAGTTGACAGCATCGCCGGGATAGAGCTTAAACTCCAATCAAGTGT
TTGCTCTATGGTGGGCCGCA

Downstream 100 bases:

>100_bases
GGCGCGCAAGCAAGAAGGCCCGGCGATGCCGGGCCTGGTCTTGGCGGATGAGCCGGAATCAGATCAGCAGCTTGCCGTCC
TTGGCCGGCAGCGTCTTGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKFPVELILLALAPVFLLFVAWELWLFRRQGRLGLYHWRDSLCSAALGLLHQGADKLAWVLVLPLYGWIYQHHRLFDFSA
GWLSFFLLFLGQDFLYYWFHRVSHRVRWLWAAHSVHHSSTRMNFTTAFRQSLMYPLAGMWAFWLPLAWLGFPPEQVVAVV
LLNLAFQFFVHTQAAPKLGWLEYVFNTPSIHRGHHAKNPRYIDHNYAGVLVVWDRLFGTYAEELDSDPCDYGTVKPVNSF
NPLWVSLVEWRDMLAEAWHARNWRDRLVLLFGPPEAAEKVAERQRAGEARRAAA

Sequences:

>Translated_294_residues
MKFPVELILLALAPVFLLFVAWELWLFRRQGRLGLYHWRDSLCSAALGLLHQGADKLAWVLVLPLYGWIYQHHRLFDFSA
GWLSFFLLFLGQDFLYYWFHRVSHRVRWLWAAHSVHHSSTRMNFTTAFRQSLMYPLAGMWAFWLPLAWLGFPPEQVVAVV
LLNLAFQFFVHTQAAPKLGWLEYVFNTPSIHRGHHAKNPRYIDHNYAGVLVVWDRLFGTYAEELDSDPCDYGTVKPVNSF
NPLWVSLVEWRDMLAEAWHARNWRDRLVLLFGPPEAAEKVAERQRAGEARRAAA
>Mature_294_residues
MKFPVELILLALAPVFLLFVAWELWLFRRQGRLGLYHWRDSLCSAALGLLHQGADKLAWVLVLPLYGWIYQHHRLFDFSA
GWLSFFLLFLGQDFLYYWFHRVSHRVRWLWAAHSVHHSSTRMNFTTAFRQSLMYPLAGMWAFWLPLAWLGFPPEQVVAVV
LLNLAFQFFVHTQAAPKLGWLEYVFNTPSIHRGHHAKNPRYIDHNYAGVLVVWDRLFGTYAEELDSDPCDYGTVKPVNSF
NPLWVSLVEWRDMLAEAWHARNWRDRLVLLFGPPEAAEKVAERQRAGEARRAAA

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=269, Percent_Identity=36.0594795539033, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI25144659, Length=240, Percent_Identity=34.1666666666667, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 34448; Mature: 34448

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]