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The map label for this gene is yhdH [H]

Identifier: 34499824

GI number: 34499824

Start: 4711385

End: 4712698

Strand: Reverse

Name: yhdH [H]

Synonym: CV_4369

Alternate gene names: 34499824

Gene position: 4712698-4711385 (Counterclockwise)

Preceding gene: 34499825

Following gene: 34499819

Centisome position: 99.19

GC content: 69.94

Gene sequence:

>1314_bases
ATGCCACGCACGCAATGGGGTTCCCGCCTCGGTTTCATTCTGGCTTCGGCCGGCGCCACGGTGGGCCTCGGTTCCATCTG
GAAATTCCCCTATGTCACCGCCATGAATGGCGGCGGCGCCTTCCTGCTGGTCTATCTGGCCTTCACCTTCACCCTGGGGC
TGGCCTTGCTGCAGGCCGAGCTGGCGCTGGGCCGCGCGGCCGGCTGCGGCGCGGTCGGCGCGTTCTCCCGGCTGGGCTCG
CCGCGCTGGAAGCTGCTGGGCTACGGCGGCGTGCTGTGCTGCTTCCTGATATTTTCCTTTTACAGCGTGGTCGGCGGCTG
GACGCTGGGCTATCTGCTGCGCGCGCTGGACGGCCGGGTGATGAGCGATGACGCGGGCGCGCTGGCCGCGCTGTTCGGCC
AGTACGTCGGCGATCCTGCCGAGGCGCTGCTGACCCACGCGCTGTTCGCCGGCCTGACGCTGCTGGTGGTGGCGGGCGGC
ATCCAGAAGGGCATAGAGCGCGCCGGCAAGCTGCTGATGCCGCTGCTGTTCCTGCTGATGCTGGCGCTGATCGTCCGCGC
CGTGACGCTGCCCGGCGCGATGGCCGGGGTGGCGGCGCTGTTCCGCCCCGATTTTAGCCGGCTGACGCCGGGCATGCTGG
TGGAGGCGCTGGGCCTGGCCTGCTTCTCGTTGTCGGTGGGCGCCGGCTGCATGTTGGCTTACGGCTCCTACCTGGGGCCG
GGCACCCGGCTCGGCAATTCGGCGCTGTGGGTGACCGGGCTGACCGCGCTGACCTCGGTGCTGGCCGGCTTGATGATCTT
TCCCGCCATCTACGCCTTCGGCCTGAATCCGCAGGCCGGCCCGGGCCTGACTTATATGGTGATGCCGGTGGTGTTCAACC
ATCTGCCCTACGGCCAGCTGTTCGCGACGGCCTTCTTCGCGCTGCTGCTGATGGCGGCGCTGACCTCGGCGGTGTCGCTG
CTGGAGGTGGTGGCCATCCTGCCGATAGACGAATTCGGCGTCGGCCGGCGCCAGGCCACGCTGGCGGTGACCGCGCTGGC
CTTCCTGGCCGGCGTGCCGGCGGCGCTGTCCTTCGGTCCGCTGGCCGATTGCAAGCTGTTCGGCCGCACCGCGTTCGAGC
TGATGGACTACGCCGCGTCCAATGTGCTGCTGCCTTTGGGCTGCATTGGCACCGCGCTGTTCGCCGGACGGGTGGCGTGG
CCGGCGGTGCGCGACGAGCTGCGGCTGTCCGCGCCGGCGGCGACGCTGATGCGCGGCGCCTGCCGCTGGCTGGCGCCGCT
GCTGATAGGCCTGGTGCTGGCCTACAACCTATAG

Upstream 100 bases:

>100_bases
GTGTTCACATCCGCTTTCCGGGCCGCCGTCATGGGCGGCCTTGTTGTATCCAGCTTTTTATCCCCATGCGGCGGCAAACT
GTTCCAACTCAGGAGTTGTC

Downstream 100 bases:

>100_bases
CAGCCAGCGCAGCGCGCCGTAGACGGCGAAGCTGACCACGATGGCCAGCAGCGTCTTGCCGTTTTTCCAGGCGACGGCGA
TGGCGACGATGGTGCCGACA

Product: sodium/chloride ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPRTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAELALGRAAGCGAVGAFSRLGS
PRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYLLRALDGRVMSDDAGALAALFGQYVGDPAEALLTHALFAGLTLLVVAGG
IQKGIERAGKLLMPLLFLLMLALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLVEALGLACFSLSVGAGCMLAYGSYLGP
GTRLGNSALWVTGLTALTSVLAGLMIFPAIYAFGLNPQAGPGLTYMVMPVVFNHLPYGQLFATAFFALLLMAALTSAVSL
LEVVAILPIDEFGVGRRQATLAVTALAFLAGVPAALSFGPLADCKLFGRTAFELMDYAASNVLLPLGCIGTALFAGRVAW
PAVRDELRLSAPAATLMRGACRWLAPLLIGLVLAYNL

Sequences:

>Translated_437_residues
MPRTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAELALGRAAGCGAVGAFSRLGS
PRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYLLRALDGRVMSDDAGALAALFGQYVGDPAEALLTHALFAGLTLLVVAGG
IQKGIERAGKLLMPLLFLLMLALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLVEALGLACFSLSVGAGCMLAYGSYLGP
GTRLGNSALWVTGLTALTSVLAGLMIFPAIYAFGLNPQAGPGLTYMVMPVVFNHLPYGQLFATAFFALLLMAALTSAVSL
LEVVAILPIDEFGVGRRQATLAVTALAFLAGVPAALSFGPLADCKLFGRTAFELMDYAASNVLLPLGCIGTALFAGRVAW
PAVRDELRLSAPAATLMRGACRWLAPLLIGLVLAYNL
>Mature_436_residues
PRTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAELALGRAAGCGAVGAFSRLGSP
RWKLLGYGGVLCCFLIFSFYSVVGGWTLGYLLRALDGRVMSDDAGALAALFGQYVGDPAEALLTHALFAGLTLLVVAGGI
QKGIERAGKLLMPLLFLLMLALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLVEALGLACFSLSVGAGCMLAYGSYLGPG
TRLGNSALWVTGLTALTSVLAGLMIFPAIYAFGLNPQAGPGLTYMVMPVVFNHLPYGQLFATAFFALLLMAALTSAVSLL
EVVAILPIDEFGVGRRQATLAVTALAFLAGVPAALSFGPLADCKLFGRTAFELMDYAASNVLLPLGCIGTALFAGRVAWP
AVRDELRLSAPAATLMRGACRWLAPLLIGLVLAYNL

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507041, Length=394, Percent_Identity=29.9492385786802, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI21361581, Length=434, Percent_Identity=26.9585253456221, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4507043, Length=408, Percent_Identity=28.4313725490196, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI289191377, Length=400, Percent_Identity=25.75, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI289191351, Length=400, Percent_Identity=25.75, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI4557046, Length=400, Percent_Identity=25.75, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI171184408, Length=433, Percent_Identity=26.3279445727483, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI171184406, Length=433, Percent_Identity=26.3279445727483, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI171184404, Length=433, Percent_Identity=26.3279445727483, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI188528618, Length=444, Percent_Identity=24.5495495495495, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7657587, Length=437, Percent_Identity=25.858123569794, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI33354281, Length=307, Percent_Identity=28.0130293159609, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI134304856, Length=383, Percent_Identity=30.5483028720627, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI58219014, Length=305, Percent_Identity=28.8524590163934, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI92859670, Length=464, Percent_Identity=27.3706896551724, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI11181770, Length=298, Percent_Identity=29.1946308724832, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI194018524, Length=294, Percent_Identity=28.2312925170068, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI197276623, Length=433, Percent_Identity=25.635103926097, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI54607094, Length=433, Percent_Identity=25.635103926097, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI67782317, Length=509, Percent_Identity=25.3438113948919, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI67782313, Length=509, Percent_Identity=25.3438113948919, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI67782315, Length=509, Percent_Identity=25.3438113948919, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI51468073, Length=296, Percent_Identity=25.3378378378378, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI12408638, Length=275, Percent_Identity=27.6363636363636, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI5032097, Length=441, Percent_Identity=24.7165532879819, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI218563756, Length=441, Percent_Identity=25.1700680272109, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21361693, Length=114, Percent_Identity=36.8421052631579, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI197276625, Length=118, Percent_Identity=33.8983050847458, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI300360519, Length=240, Percent_Identity=28.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI289191353, Length=209, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555248, Length=409, Percent_Identity=27.8728606356968, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI133952791, Length=422, Percent_Identity=26.303317535545, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25146584, Length=409, Percent_Identity=24.9388753056235, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71995588, Length=413, Percent_Identity=24.2130750605327, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554804, Length=433, Percent_Identity=26.0969976905312, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17569475, Length=403, Percent_Identity=23.5732009925558, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115534083, Length=431, Percent_Identity=21.5777262180974, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136952, Length=436, Percent_Identity=27.2935779816514, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281364394, Length=436, Percent_Identity=27.2935779816514, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574704, Length=436, Percent_Identity=27.2935779816514, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17136950, Length=436, Percent_Identity=27.2935779816514, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574702, Length=436, Percent_Identity=27.2935779816514, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI45551183, Length=446, Percent_Identity=27.5784753363229, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24762620, Length=399, Percent_Identity=29.0726817042606, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI45550877, Length=422, Percent_Identity=28.436018957346, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24661428, Length=404, Percent_Identity=28.960396039604, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI19921936, Length=387, Percent_Identity=28.4237726098191, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45551088, Length=380, Percent_Identity=27.6315789473684, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24652942, Length=380, Percent_Identity=27.6315789473684, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI281363702, Length=377, Percent_Identity=28.1167108753316, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281365034, Length=410, Percent_Identity=25.3658536585366, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19921352, Length=419, Percent_Identity=24.582338902148, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24584353, Length=419, Percent_Identity=24.582338902148, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639853, Length=424, Percent_Identity=27.8301886792453, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281364136, Length=417, Percent_Identity=27.5779376498801, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24639514, Length=447, Percent_Identity=25.503355704698, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221329674, Length=447, Percent_Identity=25.503355704698, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363700, Length=298, Percent_Identity=29.1946308724832, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24654186, Length=526, Percent_Identity=25.0950570342205, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639516, Length=295, Percent_Identity=28.135593220339, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655079, Length=293, Percent_Identity=25.5972696245734, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24582567, Length=443, Percent_Identity=23.2505643340858, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 45481; Mature: 45350

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00610 NA_NEUROTRAN_SYMP_1 ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAE
CCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LALGRAAGCGAVGAFSRLGSPRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYLLRALDGRV
HHHHCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
MSDDAGALAALFGQYVGDPAEALLTHALFAGLTLLVVAGGIQKGIERAGKLLMPLLFLLM
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLVEALGLACFSLSVGAGCMLAYGSYLGP
HHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
GTRLGNSALWVTGLTALTSVLAGLMIFPAIYAFGLNPQAGPGLTYMVMPVVFNHLPYGQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHH
FATAFFALLLMAALTSAVSLLEVVAILPIDEFGVGRRQATLAVTALAFLAGVPAALSFGP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
LADCKLFGRTAFELMDYAASNVLLPLGCIGTALFAGRVAWPAVRDELRLSAPAATLMRGA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CRWLAPLLIGLVLAYNL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRTQWGSRLGFILASAGATVGLGSIWKFPYVTAMNGGGAFLLVYLAFTFTLGLALLQAE
CCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LALGRAAGCGAVGAFSRLGSPRWKLLGYGGVLCCFLIFSFYSVVGGWTLGYLLRALDGRV
HHHHCCCCCCHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
MSDDAGALAALFGQYVGDPAEALLTHALFAGLTLLVVAGGIQKGIERAGKLLMPLLFLLM
ECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALIVRAVTLPGAMAGVAALFRPDFSRLTPGMLVEALGLACFSLSVGAGCMLAYGSYLGP
HHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
GTRLGNSALWVTGLTALTSVLAGLMIFPAIYAFGLNPQAGPGLTYMVMPVVFNHLPYGQL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHH
FATAFFALLLMAALTSAVSLLEVVAILPIDEFGVGRRQATLAVTALAFLAGVPAALSFGP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
LADCKLFGRTAFELMDYAASNVLLPLGCIGTALFAGRVAWPAVRDELRLSAPAATLMRGA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
CRWLAPLLIGLVLAYNL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]