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The map label for this gene is mreB [H]

Identifier: 34499812

GI number: 34499812

Start: 4697801

End: 4698844

Strand: Direct

Name: mreB [H]

Synonym: CV_4357

Alternate gene names: 34499812

Gene position: 4697801-4698844 (Clockwise)

Preceding gene: 34499808

Following gene: 34499813

Centisome position: 98.88

GC content: 65.52

Gene sequence:

>1044_bases
ATGTTTCGTTCGCTGACCGGATACTTCTCCAACGACCTCGCCATCGACCTCGGCACCGCCAACACCCTGATCTACATGCG
CAGCAAGGGCATCGTCCTCGACGAGCCTTCGGTCGTCGCCATCCACAACGACGCGCCGACCAACAAAAAGTCCATCCTGG
CCGTCGGCCTGGAAGCCAAGCGCATGCTGGGCCGCACCCCGGGCAGCATCCAGGCCATCCGCCCGATGAAGGACGGCGTG
ATCGCCGACTTCACCGTCACCGAACAGATGCTGAAGCAGTTCATCAAGAAGGTGAACCCGAACCGCTTCTTCGCCGCCAG
CCCGCGCATCGTGATCTGCGTGCCCTGCGGCTCCACCCAGGTGGAGCGCAAGGCGATCCGCGACTCCGCGCTGGCCGCCG
GCGCGCGCCGCGTCGAGCTGATCGAGGAGCCGATGGCCGCCGCGATCGGCGCCGGCCTGCCGGTGGAGGAGCCGACCGGC
TCCATGGTGGTGGACATCGGCGGCGGCACCACCGAAGTGGGCGTGATCTCGCTGGGCGGCGTGGTCTACTCCAACTCGGT
GCGCGTCGGCGGCGACAAGTTCGACGAAGCCATCATCAACTACATCCGCCGCAACTACGGCATGCTGATCGGCGAAACCA
CCGCCGAGGAAATCAAGAAAACCATCGGCTCCGCCTTCCCGGGCGCCGAGGTGCGCGAAATGGAAGTCAAGGGCCGCAAC
CTGGCCGAAGGCATTCCGCGCGCGTTCACCGTGTCTTCCAACGAAATCCTGGAAGCGCTGACCGAGCCCTTGAACCAGAT
CGTCTCCGCGGTGAAGATCGCGCTGGAGCAGACCCCGCCGGAACTGGGCGCCGACATCGCCGAGAAGGGCATGGTGCTGA
CCGGCGGCGGCGCGCTGCTGAAGGACATCGACCGCCTGCTGGCGGAAGAGACCGGCCTGCCGGTGTTCGTGGCCGAGGAA
CCGCTGACCTGCGTGGTGCGCGGCTCCGGCAAGGCGCTGGAAAAAATGGACAAGATCGGCACCATTTTCACCAACGTGCC
TTAA

Upstream 100 bases:

>100_bases
CTGATAAAAAGGCGGGGAAACGGGCCTGCCACAGATTAAACTGGATTTTTACGGACGCCGCCGGCGTCCGCCACTGACGA
AAACTGACCAGGACCGCCCA

Downstream 100 bases:

>100_bases
ACTTCCAGCAACGAACTAAACCGAGCGAACGCCGCGCCGTCAAGGCGCGGTGGCTGTGGCCATGGATTTCGCCAACACCC
CTAGCTTCTTCCGCTCCGGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFRSLTGYFSNDLAIDLGTANTLIYMRSKGIVLDEPSVVAIHNDAPTNKKSILAVGLEAKRMLGRTPGSIQAIRPMKDGV
IADFTVTEQMLKQFIKKVNPNRFFAASPRIVICVPCGSTQVERKAIRDSALAAGARRVELIEEPMAAAIGAGLPVEEPTG
SMVVDIGGGTTEVGVISLGGVVYSNSVRVGGDKFDEAIINYIRRNYGMLIGETTAEEIKKTIGSAFPGAEVREMEVKGRN
LAEGIPRAFTVSSNEILEALTEPLNQIVSAVKIALEQTPPELGADIAEKGMVLTGGGALLKDIDRLLAEETGLPVFVAEE
PLTCVVRGSGKALEKMDKIGTIFTNVP

Sequences:

>Translated_347_residues
MFRSLTGYFSNDLAIDLGTANTLIYMRSKGIVLDEPSVVAIHNDAPTNKKSILAVGLEAKRMLGRTPGSIQAIRPMKDGV
IADFTVTEQMLKQFIKKVNPNRFFAASPRIVICVPCGSTQVERKAIRDSALAAGARRVELIEEPMAAAIGAGLPVEEPTG
SMVVDIGGGTTEVGVISLGGVVYSNSVRVGGDKFDEAIINYIRRNYGMLIGETTAEEIKKTIGSAFPGAEVREMEVKGRN
LAEGIPRAFTVSSNEILEALTEPLNQIVSAVKIALEQTPPELGADIAEKGMVLTGGGALLKDIDRLLAEETGLPVFVAEE
PLTCVVRGSGKALEKMDKIGTIFTNVP
>Mature_347_residues
MFRSLTGYFSNDLAIDLGTANTLIYMRSKGIVLDEPSVVAIHNDAPTNKKSILAVGLEAKRMLGRTPGSIQAIRPMKDGV
IADFTVTEQMLKQFIKKVNPNRFFAASPRIVICVPCGSTQVERKAIRDSALAAGARRVELIEEPMAAAIGAGLPVEEPTG
SMVVDIGGGTTEVGVISLGGVVYSNSVRVGGDKFDEAIINYIRRNYGMLIGETTAEEIKKTIGSAFPGAEVREMEVKGRN
LAEGIPRAFTVSSNEILEALTEPLNQIVSAVKIALEQTPPELGADIAEKGMVLTGGGALLKDIDRLLAEETGLPVFVAEE
PLTCVVRGSGKALEKMDKIGTIFTNVP

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=340, Percent_Identity=72.9411764705882, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1788875, Length=235, Percent_Identity=28.5106382978723, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319972, Length=366, Percent_Identity=24.0437158469945, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324120, Length=366, Percent_Identity=24.0437158469945, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6323401, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320950, Length=232, Percent_Identity=25, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36943; Mature: 36943

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSLTGYFSNDLAIDLGTANTLIYMRSKGIVLDEPSVVAIHNDAPTNKKSILAVGLEAK
CCCCCCCCCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCEEEEECCHHH
RMLGRTPGSIQAIRPMKDGVIADFTVTEQMLKQFIKKVNPNRFFAASPRIVICVPCGSTQ
HHHCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCH
VERKAIRDSALAAGARRVELIEEPMAAAIGAGLPVEEPTGSMVVDIGGGTTEVGVISLGG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECC
VVYSNSVRVGGDKFDEAIINYIRRNYGMLIGETTAEEIKKTIGSAFPGAEVREMEVKGRN
EEEECCEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCC
LAEGIPRAFTVSSNEILEALTEPLNQIVSAVKIALEQTPPELGADIAEKGMVLTGGGALL
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCEEEECCCHHH
KDIDRLLAEETGLPVFVAEEPLTCVVRGSGKALEKMDKIGTIFTNVP
HHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFRSLTGYFSNDLAIDLGTANTLIYMRSKGIVLDEPSVVAIHNDAPTNKKSILAVGLEAK
CCCCCCCCCCCCEEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCCCEEEEECCHHH
RMLGRTPGSIQAIRPMKDGVIADFTVTEQMLKQFIKKVNPNRFFAASPRIVICVPCGSTQ
HHHCCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCH
VERKAIRDSALAAGARRVELIEEPMAAAIGAGLPVEEPTGSMVVDIGGGTTEVGVISLGG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECC
VVYSNSVRVGGDKFDEAIINYIRRNYGMLIGETTAEEIKKTIGSAFPGAEVREMEVKGRN
EEEECCEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHHCCCCCCCCEEEEECCCCC
LAEGIPRAFTVSSNEILEALTEPLNQIVSAVKIALEQTPPELGADIAEKGMVLTGGGALL
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCEEEECCCHHH
KDIDRLLAEETGLPVFVAEEPLTCVVRGSGKALEKMDKIGTIFTNVP
HHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]