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The map label for this gene is ftsW [H]

Identifier: 34499799

GI number: 34499799

Start: 4683755

End: 4684912

Strand: Reverse

Name: ftsW [H]

Synonym: CV_4344

Alternate gene names: 34499799

Gene position: 4684912-4683755 (Counterclockwise)

Preceding gene: 34499800

Following gene: 34499798

Centisome position: 98.61

GC content: 62.95

Gene sequence:

>1158_bases
ATGAACCACAATCCGGCGCGCCGCTACACGGCGATCACCGCTCTGGACGAGGCGCTGGCCTGGGCGCTGGCGCTGCTGCT
GTCGATCAGCCTGGTGATGGTGTATTCGGCGTCCATCGCCTACGCGGAAGCCGACGCGGCGACGCAGAACCGCTACTTCT
ACCTGATCCGCCACATCGTGTTCATGGTGATCGGGCTGTCGGCGGCGTTCGCGGCGTTCCAGATACCGACGGCGTTCTGG
CAGAAGTATTCGGGGAAGATTTTCCTGATCGGCTTGGTGATGCTGGTGCTGGTGCTGATTCCCGGCATCGGCAAGGTGGT
CAACGGCTCGCGGCGCTGGATCAACCTGTTCGTGCTGAATTTGCAGCCGTCGGAGGTGATGAAGTTCGCCACCGTGCTGT
ACGCGGCCGATTACACGGTGCGCAAGAGCCACCTGCTGCACAGCATCAAGGAAGGCTTCGCGCCGATGTTCGCGGCGATG
GTGGTGGTGGCTTTCCTGCTGCTGCGCGAGCCGGACTTCGGCGCGCTGATGGTGGTGATGAGCATCGCGATGGGCCTGCT
GTTCCTGGGCGGCATCAATATGCGCATCTTTTCGGGGCTGGCGGCGATGGCGGTGGTGGCCATCGTGCTGCTGATCGTGT
CGTCGCCGTACCGGCTGAAGCGGGTGCTGGGCTTCATGGACCCGTGGGACGACCCGTACGGCAAGGGCTACCAGCTGAGC
CATTCGCTGATCGCCATCGGCCGCGGCGAATGGTTCGGCGTCGGCCTGGGCGGCAGCATCGAGAAGCTGTTCTACCTGCC
GGAGGCGCACACCGACTTCATCATGGCGGTGATCGCCGAGGAGTTCGGCTTCGCCGGCATCTGCGTGGTGATCGGCCTCT
ATGCTTGGATCGTGCGCCGCGCCTTCCACATCGGGGTGGAGTCGAAAAAGCTGGAGCGCTACTACCAGGCGCTGGTGGCG
CAGGGCATCGGCATTTGGCTGGGCATCCAGGTGTTTTTCAACATTGGCGTGAACATGGGCCTGTTGCCGACCAAGGGTCT
GACGCTGCCGCTGATGTCCTTCGGCGGTTCGGCGATGCTGATGAATTTGATCGCGGTGGCGGTGCTGCTGCGGGTTGATT
ATGAGAACCGGCGCATCATGCGCGGGTACAAGGTTTGA

Upstream 100 bases:

>100_bases
TGCTGTCGCCGGCCTGCGCCAGCCTGGACATGTTCAAGAATTACGCGCACCGGGCGCAGGTGTTCATCGACACCGTGGCG
GCGGTGAAGGCGGCGCGGGC

Downstream 100 bases:

>100_bases
GAGAAATGGCGAATCGCACGGTCATGGTGATGGCGGCTGGCACGGGCGGACACATCGTCCCCGGCCTCGCCGTGGCCAAG
GAATTGCAAAGCCGCGGCTG

Product: cell division protein ftsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MNHNPARRYTAITALDEALAWALALLLSISLVMVYSASIAYAEADAATQNRYFYLIRHIVFMVIGLSAAFAAFQIPTAFW
QKYSGKIFLIGLVMLVLVLIPGIGKVVNGSRRWINLFVLNLQPSEVMKFATVLYAADYTVRKSHLLHSIKEGFAPMFAAM
VVVAFLLLREPDFGALMVVMSIAMGLLFLGGINMRIFSGLAAMAVVAIVLLIVSSPYRLKRVLGFMDPWDDPYGKGYQLS
HSLIAIGRGEWFGVGLGGSIEKLFYLPEAHTDFIMAVIAEEFGFAGICVVIGLYAWIVRRAFHIGVESKKLERYYQALVA
QGIGIWLGIQVFFNIGVNMGLLPTKGLTLPLMSFGGSAMLMNLIAVAVLLRVDYENRRIMRGYKV

Sequences:

>Translated_385_residues
MNHNPARRYTAITALDEALAWALALLLSISLVMVYSASIAYAEADAATQNRYFYLIRHIVFMVIGLSAAFAAFQIPTAFW
QKYSGKIFLIGLVMLVLVLIPGIGKVVNGSRRWINLFVLNLQPSEVMKFATVLYAADYTVRKSHLLHSIKEGFAPMFAAM
VVVAFLLLREPDFGALMVVMSIAMGLLFLGGINMRIFSGLAAMAVVAIVLLIVSSPYRLKRVLGFMDPWDDPYGKGYQLS
HSLIAIGRGEWFGVGLGGSIEKLFYLPEAHTDFIMAVIAEEFGFAGICVVIGLYAWIVRRAFHIGVESKKLERYYQALVA
QGIGIWLGIQVFFNIGVNMGLLPTKGLTLPLMSFGGSAMLMNLIAVAVLLRVDYENRRIMRGYKV
>Mature_385_residues
MNHNPARRYTAITALDEALAWALALLLSISLVMVYSASIAYAEADAATQNRYFYLIRHIVFMVIGLSAAFAAFQIPTAFW
QKYSGKIFLIGLVMLVLVLIPGIGKVVNGSRRWINLFVLNLQPSEVMKFATVLYAADYTVRKSHLLHSIKEGFAPMFAAM
VVVAFLLLREPDFGALMVVMSIAMGLLFLGGINMRIFSGLAAMAVVAIVLLIVSSPYRLKRVLGFMDPWDDPYGKGYQLS
HSLIAIGRGEWFGVGLGGSIEKLFYLPEAHTDFIMAVIAEEFGFAGICVVIGLYAWIVRRAFHIGVESKKLERYYQALVA
QGIGIWLGIQVFFNIGVNMGLLPTKGLTLPLMSFGGSAMLMNLIAVAVLLRVDYENRRIMRGYKV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=40.3314917127072, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1786853, Length=351, Percent_Identity=30.7692307692308, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42587; Mature: 42587

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHNPARRYTAITALDEALAWALALLLSISLVMVYSASIAYAEADAATQNRYFYLIRHIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
FMVIGLSAAFAAFQIPTAFWQKYSGKIFLIGLVMLVLVLIPGIGKVVNGSRRWINLFVLN
HHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEEEE
LQPSEVMKFATVLYAADYTVRKSHLLHSIKEGFAPMFAAMVVVAFLLLREPDFGALMVVM
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIAMGLLFLGGINMRIFSGLAAMAVVAIVLLIVSSPYRLKRVLGFMDPWDDPYGKGYQLS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEC
HSLIAIGRGEWFGVGLGGSIEKLFYLPEAHTDFIMAVIAEEFGFAGICVVIGLYAWIVRR
CCEEEEECCCEEEECCCCCHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AFHIGVESKKLERYYQALVAQGIGIWLGIQVFFNIGVNMGLLPTKGLTLPLMSFGGSAML
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHH
MNLIAVAVLLRVDYENRRIMRGYKV
HHHHHHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure
MNHNPARRYTAITALDEALAWALALLLSISLVMVYSASIAYAEADAATQNRYFYLIRHIV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
FMVIGLSAAFAAFQIPTAFWQKYSGKIFLIGLVMLVLVLIPGIGKVVNGSRRWINLFVLN
HHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEEEE
LQPSEVMKFATVLYAADYTVRKSHLLHSIKEGFAPMFAAMVVVAFLLLREPDFGALMVVM
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIAMGLLFLGGINMRIFSGLAAMAVVAIVLLIVSSPYRLKRVLGFMDPWDDPYGKGYQLS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEC
HSLIAIGRGEWFGVGLGGSIEKLFYLPEAHTDFIMAVIAEEFGFAGICVVIGLYAWIVRR
CCEEEEECCCEEEECCCCCHHHHEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AFHIGVESKKLERYYQALVAQGIGIWLGIQVFFNIGVNMGLLPTKGLTLPLMSFGGSAML
HHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCHHHH
MNLIAVAVLLRVDYENRRIMRGYKV
HHHHHHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]