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The map label for this gene is ribB

Identifier: 34499671

GI number: 34499671

Start: 4551282

End: 4551914

Strand: Direct

Name: ribB

Synonym: CV_4216

Alternate gene names: 34499671

Gene position: 4551282-4551914 (Clockwise)

Preceding gene: 34499668

Following gene: 34499672

Centisome position: 95.79

GC content: 72.51

Gene sequence:

>633_bases
ATGAACGCCAACACCGACATCCTATCCCTGCGCGTCCACGCCGCGCTGGACGCCTTGCGCCGCGGCCTGCCGGTCATCGT
CGCCGACGACGCCGACCGCGAGAACGAGGCCGACCTGATCCTGGCCGCCGACACGCTCACCGTGCCCGAAATGGCGCGGA
TGATCCGCGACGGCAGCGGCATCGTCTGCCTGTGCCTCACGCCGGAGCGCGCCGAACGGCTGCAGTTGCCGCCGATGGCC
GCCGAGAACGGCAGCCGCTACGGCACCGCCTTCACCGTCGCCATCGAGGCAGCCCAAGGCGTCACCACCGGCGTGTCCGC
AGCCGACCGCACCACCACCATCCGCGCCGCCATCCATCCCGACGCCAAGCCCGGCGACCTGGTGCGGCCCGGCCACGTCT
ATCCCATCGTCGCCCGCGCCGGCGGCGTGCGCGAGCGCCGCGGCCACACCGAGGCCTCGGTGGAGCTGGCGCGGCTGGCC
GGCTTCAGCCCGGCCGGCGTGCTGTGCGAGCTGATGAACCCGGACGGCACGATGATGCGCGGCCAGCAAGTGCAGGATTA
CGCCGAGCGCCACGATCTGCCGCAGCTGTCGGTCGCCGAGCTGGCCGAATGGCTGCAGCGCGAACCGGCTTGA

Upstream 100 bases:

>100_bases
CGTGTCGTATCCGCGCGGTTTCCCGCGCCGGATGGCTTTGCGCTATCCGCTTCAAGCCCGAGGGACGTGTTTCTCAATCT
TGTTTTTGAGGACCGTTTCC

Downstream 100 bases:

>100_bases
GGAGGCGCGACATGTTCACCGGCATCACCCAGGCCGTCGGCCGCATCGCCGCCATCTCCGAAGGCGAAGCCAGCCGCCGC
GTCGCCATCGACTTCCCGGA

Product: 3,4-dihydroxy-2-butanone 4-phosphatesynthase protein

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSGIVCLCLTPERAERLQLPPMA
AENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHPDAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLA
GFSPAGVLCELMNPDGTMMRGQQVQDYAERHDLPQLSVAELAEWLQREPA

Sequences:

>Translated_210_residues
MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSGIVCLCLTPERAERLQLPPMA
AENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHPDAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLA
GFSPAGVLCELMNPDGTMMRGQQVQDYAERHDLPQLSVAELAEWLQREPA
>Mature_210_residues
MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSGIVCLCLTPERAERLQLPPMA
AENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHPDAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLA
GFSPAGVLCELMNPDGTMMRGQQVQDYAERHDLPQLSVAELAEWLQREPA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=58.6734693877551, Blast_Score=231, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=42.156862745098, Blast_Score=175, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_CHRVO (Q7NQC4)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903886.1
- ProteinModelPortal:   Q7NQC4
- SMR:   Q7NQC4
- GeneID:   2549626
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_4216
- NMPDR:   fig|243365.1.peg.4216
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- PhylomeDB:   Q7NQC4
- BioCyc:   CVIO243365:CV_4216-MONOMER
- BRENDA:   4.1.99.12
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 22524; Mature: 22524

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: BINDING 38-38 BINDING 170-170

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSG
CCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
IVCLCLTPERAERLQLPPMAAENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHP
EEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECC
DAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLAGFSPAGVLCELMNPDGTMMR
CCCCCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHCCCCCHHHEEEEECCCCCEEC
GQQVQDYAERHDLPQLSVAELAEWLQREPA
CHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSG
CCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
IVCLCLTPERAERLQLPPMAAENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHP
EEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEECC
DAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLAGFSPAGVLCELMNPDGTMMR
CCCCCCCCCCCCEEEEEECCCCCHHHCCCCHHHHHHHHHCCCCCHHHEEEEECCCCCEEC
GQQVQDYAERHDLPQLSVAELAEWLQREPA
CHHHHHHHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782