Click here to switch to the map view.

The map label for this gene is idsA [H]

Identifier: 34499409

GI number: 34499409

Start: 4274545

End: 4275561

Strand: Reverse

Name: idsA [H]

Synonym: CV_3954

Alternate gene names: 34499409

Gene position: 4275561-4274545 (Counterclockwise)

Preceding gene: 34499410

Following gene: 34499408

Centisome position: 89.99

GC content: 68.83

Gene sequence:

>1017_bases
GTGCTGGCGACGATAGACCGGTTGGCGAGCCGCCCGTATCTGGAAACCGCGCTGGGCGCGCGGCTGTCCGAGGCCATGCT
GCAGGCGGTGAAGGATGCCTGGCTCGATCCCTACCGTTCCTACCACAACCGGATGGGCAAGATGCTGCGCCCCTTCCTGG
TATGCAGCGTGATGCAGGCCTTCGAGCGCGATCCGCGACGGACGCCGGTCGTGGTGGCGATCGCCGAGATCATCCACGCC
GCCTCGCTGGTGCTGGACGATGTCGCAGACGACTCGCCGCTGCGCCGCGGCGGGCCGACCGCGCATCGCCAAGTCGGCGT
CCGCGTCGCCGGTGCCGCAGGCTCCGCCTGGCTGAACGCCTGCTTCCAGCTGCTGGCCGCCGACGATTCCGGCCTGGAGC
CGGAACAGGCGCAGCGCCTGGCCGACGAGATCGCCTGGGAGCACTGGGTGACCGGCGTCGGCACCACGATAGACACCACC
TGGCCGTGGATGGGGCGGCTGGACGGCACGCCGGCGCAGTATCTGCAGTCGGTGGTGCACCGTTCCACTTCCTATACCTA
CCGCTTGCCGCTGAAGCTGGGCGCGATCGCGGCCGGCGCGTCGCCGCAGCAAACCGCGCAATTCGCCGCGCTGGGCGAGG
AGCTGGGCATCGCCTTCCAGATCATCGACGACATCCTCAATGTGCAGCCGGGTGACGACAAGTGGGGCAAGGCGCTGGCC
GAGGACATCACCCAGGGCAAGATCAATCTGCAGGTGCTGCTGGCGCTGGAGCGGCTGGGATCTGCCGAGCGGGCCAGGCT
GGTGGAGATCCTGCAGAGCCGCACCGCCGACCCCCAGACGCTGGCCGAGGCGGTGGCGCTGATGGCCGGCAGCGGCGCTT
TCGACGCCGCGCGCGACATCGCCCAAGGGTATATCGACAGCACCCAGGCCATCGTCGCCGGAATGGACTTCCTCAACCCG
GTCGACCGCGAACGCTTCTCCGCCTTCGTCGACTACGTGATCCACCGCAATCGCTGA

Upstream 100 bases:

>100_bases
GATGAACGGCAACGCGCAGTATAGCGACGATTTCCTGGCCGACATGGCGCCCGCGCTGGCGCAGCAGTACCGCCGCTGGT
ACCCGTGGTGCCGCGAGACG

Downstream 100 bases:

>100_bases
ATGGAACCGCCCGCCAAAGGCGGGCATCGGCTTCGGCTGCGCAAAGGTGATGGCAAATGAGTTTTGTCGCTCAGGAAATG
CAGGGAACGGTATTGCTGAC

Product: bifunctional short chain isoprenyl diphosphate

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLATIDRLASRPYLETALGARLSEAMLQAVKDAWLDPYRSYHNRMGKMLRPFLVCSVMQAFERDPRRTPVVVAIAEIIHA
ASLVLDDVADDSPLRRGGPTAHRQVGVRVAGAAGSAWLNACFQLLAADDSGLEPEQAQRLADEIAWEHWVTGVGTTIDTT
WPWMGRLDGTPAQYLQSVVHRSTSYTYRLPLKLGAIAAGASPQQTAQFAALGEELGIAFQIIDDILNVQPGDDKWGKALA
EDITQGKINLQVLLALERLGSAERARLVEILQSRTADPQTLAEAVALMAGSGAFDAARDIAQGYIDSTQAIVAGMDFLNP
VDRERFSAFVDYVIHRNR

Sequences:

>Translated_338_residues
MLATIDRLASRPYLETALGARLSEAMLQAVKDAWLDPYRSYHNRMGKMLRPFLVCSVMQAFERDPRRTPVVVAIAEIIHA
ASLVLDDVADDSPLRRGGPTAHRQVGVRVAGAAGSAWLNACFQLLAADDSGLEPEQAQRLADEIAWEHWVTGVGTTIDTT
WPWMGRLDGTPAQYLQSVVHRSTSYTYRLPLKLGAIAAGASPQQTAQFAALGEELGIAFQIIDDILNVQPGDDKWGKALA
EDITQGKINLQVLLALERLGSAERARLVEILQSRTADPQTLAEAVALMAGSGAFDAARDIAQGYIDSTQAIVAGMDFLNP
VDRERFSAFVDYVIHRNR
>Mature_338_residues
MLATIDRLASRPYLETALGARLSEAMLQAVKDAWLDPYRSYHNRMGKMLRPFLVCSVMQAFERDPRRTPVVVAIAEIIHA
ASLVLDDVADDSPLRRGGPTAHRQVGVRVAGAAGSAWLNACFQLLAADDSGLEPEQAQRLADEIAWEHWVTGVGTTIDTT
WPWMGRLDGTPAQYLQSVVHRSTSYTYRLPLKLGAIAAGASPQQTAQFAALGEELGIAFQIIDDILNVQPGDDKWGKALA
EDITQGKINLQVLLALERLGSAERARLVEILQSRTADPQTLAEAVALMAGSGAFDAARDIAQGYIDSTQAIVAGMDFLNP
VDRERFSAFVDYVIHRNR

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI4758430, Length=277, Percent_Identity=22.7436823104693, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI83700220, Length=277, Percent_Identity=22.7436823104693, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1789578, Length=257, Percent_Identity=25.6809338521401, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786623, Length=222, Percent_Identity=31.0810810810811, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17505681, Length=211, Percent_Identity=30.3317535545024, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24651612, Length=309, Percent_Identity=24.2718446601942, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36892; Mature: 36892

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLATIDRLASRPYLETALGARLSEAMLQAVKDAWLDPYRSYHNRMGKMLRPFLVCSVMQA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FERDPRRTPVVVAIAEIIHAASLVLDDVADDSPLRRGGPTAHRQVGVRVAGAAGSAWLNA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHH
CFQLLAADDSGLEPEQAQRLADEIAWEHWVTGVGTTIDTTWPWMGRLDGTPAQYLQSVVH
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RSTSYTYRLPLKLGAIAAGASPQQTAQFAALGEELGIAFQIIDDILNVQPGDDKWGKALA
CCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EDITQGKINLQVLLALERLGSAERARLVEILQSRTADPQTLAEAVALMAGSGAFDAARDI
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHH
AQGYIDSTQAIVAGMDFLNPVDRERFSAFVDYVIHRNR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLATIDRLASRPYLETALGARLSEAMLQAVKDAWLDPYRSYHNRMGKMLRPFLVCSVMQA
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
FERDPRRTPVVVAIAEIIHAASLVLDDVADDSPLRRGGPTAHRQVGVRVAGAAGSAWLNA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHH
CFQLLAADDSGLEPEQAQRLADEIAWEHWVTGVGTTIDTTWPWMGRLDGTPAQYLQSVVH
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RSTSYTYRLPLKLGAIAAGASPQQTAQFAALGEELGIAFQIIDDILNVQPGDDKWGKALA
CCCCCEEEECHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
EDITQGKINLQVLLALERLGSAERARLVEILQSRTADPQTLAEAVALMAGSGAFDAARDI
HHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHH
AQGYIDSTQAIVAGMDFLNPVDRERFSAFVDYVIHRNR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]