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The map label for this gene is fabZ [H]

Identifier: 34499405

GI number: 34499405

Start: 4271449

End: 4271892

Strand: Reverse

Name: fabZ [H]

Synonym: CV_3950

Alternate gene names: 34499405

Gene position: 4271892-4271449 (Counterclockwise)

Preceding gene: 34499406

Following gene: 34499404

Centisome position: 89.91

GC content: 70.5

Gene sequence:

>444_bases
ATGGCGGCGCGGCGCTTCACCGGCGACGAGTTGGCGGCGCTGCTGCCGCACGCCGGCGACGCCTTTTTCCTCAGGGATGC
CGAGGTAGACGGCTGGCGCGCCAGCGGCGGCGCCAGCTGGCGGTCCGACCATCCCCACCTGCGCGGGCACTTTCCGGGCG
AGCCCATCGTGCCCGGGGTCTATTTGCTGGAGGCGGCGGCGCAATTGGCGGGCGTGGCGATACGTTGCGGCGCGGAGGAC
TGGACGCCGGAAACGCTGGGCGTGTTGGCTGGGGTGCGCAAATCCTACTTCCACCGCTTCGTCCGGCCGGGCGAGCGGGT
GGATTATGCGCTGGACGTGAAGCCTGCGCCTGGCAGCGCGATGTACGCGGTCAGCGGGCTGGGCAAGGTGGACGGGGACA
AGGTGCTGACCGTGGAATTGACGATAGCCGGCGTGCGGCGCTAG

Upstream 100 bases:

>100_bases
GCTATGTGCTGGACACCTTCGGCGACGGCGCGGCCCGCCGTTTCATCGAGCTGGACCTGGAAGCGGTGACGGCTTTTGAC
GCCGAGGAGGATCTGTAGCC

Downstream 100 bases:

>100_bases
CGCGGCGGCGGGAGGGGGCATGGACAAGCGAAGAGTGGTGATCACCGGCATCGGCGTGGTGTCGCCTTACGGCGCCGGCC
TGCAGCGTTTCTGGCAGGCG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: 2-hexadecenoyl-[acyl-carrier protein]; H2O

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MAARRFTGDELAALLPHAGDAFFLRDAEVDGWRASGGASWRSDHPHLRGHFPGEPIVPGVYLLEAAAQLAGVAIRCGAED
WTPETLGVLAGVRKSYFHRFVRPGERVDYALDVKPAPGSAMYAVSGLGKVDGDKVLTVELTIAGVRR

Sequences:

>Translated_147_residues
MAARRFTGDELAALLPHAGDAFFLRDAEVDGWRASGGASWRSDHPHLRGHFPGEPIVPGVYLLEAAAQLAGVAIRCGAED
WTPETLGVLAGVRKSYFHRFVRPGERVDYALDVKPAPGSAMYAVSGLGKVDGDKVLTVELTIAGVRR
>Mature_146_residues
AARRFTGDELAALLPHAGDAFFLRDAEVDGWRASGGASWRSDHPHLRGHFPGEPIVPGVYLLEAAAQLAGVAIRCGAEDW
TPETLGVLAGVRKSYFHRFVRPGERVDYALDVKPAPGSAMYAVSGLGKVDGDKVLTVELTIAGVRR

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.61

Molecular weight: Translated: 15752; Mature: 15621

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARRFTGDELAALLPHAGDAFFLRDAEVDGWRASGGASWRSDHPHLRGHFPGEPIVPGV
CCCCCCCCHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHH
YLLEAAAQLAGVAIRCGAEDWTPETLGVLAGVRKSYFHRFVRPGERVDYALDVKPAPGSA
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCE
MYAVSGLGKVDGDKVLTVELTIAGVRR
EEEECCCCCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure 
AARRFTGDELAALLPHAGDAFFLRDAEVDGWRASGGASWRSDHPHLRGHFPGEPIVPGV
CCCCCCCHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCHH
YLLEAAAQLAGVAIRCGAEDWTPETLGVLAGVRKSYFHRFVRPGERVDYALDVKPAPGSA
HHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCE
MYAVSGLGKVDGDKVLTVELTIAGVRR
EEEECCCCCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein]

Specific reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA