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The map label for this gene is dppA [H]

Identifier: 34499391

GI number: 34499391

Start: 4255548

End: 4257212

Strand: Direct

Name: dppA [H]

Synonym: CV_3936

Alternate gene names: 34499391

Gene position: 4255548-4257212 (Clockwise)

Preceding gene: 34499386

Following gene: 34499392

Centisome position: 89.57

GC content: 63.36

Gene sequence:

>1665_bases
GTGTGCGATACTCTGCAGGCATATCGATACCGACGCGCGGCCGATCGCCGCCGCGCGCGAACCATCAGGAAAACGGACAT
GATCCTCTCCCGTTCCCTTCGCGCCCTGTCGCTGTCCCTGGCGCTGGCCACGGCCTTGCCCGCCCTCGCCGCCAAACCAC
TGGTCTTTTGCGCGGAAGCCTCGCCGGAAGGCTTCGATCCGGCGATGTGGGACAGCGCCACCACCTACAACATCACCAAG
CCGGTGTTCCAAGGCCTGGTCGAGTTCAAGCGCGGCGGCGTCGCGCTGCGGCCCGGCCTGGCCGAAAGCTGGTCGGTGTC
GCCCGATGGACTGGTATATACATTCAGACTCCGTCGCAACGTCAAGTTCCATCAGACCGCCTATTTCACCCCCAGCCGCG
ACTTCTCCGCCGACGACGCCGTCTTCACCGTCAACCGCTGGATACGCCCCGAGCTGCCGTTCAACCAGGCGCTCAGAACA
CCGTTGACCGGACCGGACGGCTACGGCCTCGCCAAGCTGATCGACTCGGTGCAGAAGGTGGACGACCATACCGTCAGGAT
AAGGCTGAAAGAACGCAACGCCACCTTCCTCACTTTCTTCGCGATGGGCTTCGCCGGCATGCAGTCGGCCGAATACGCCG
ACCAACTGCTGAAAGCCGGCAAGCCGCAACAGCTCAATCTGCTGCCGATCGGCACCGGTCCCTATCGCTTCAAGAGCTAC
GCCAAGGATGCCATCATCCGCTACGAGGCCCATCCGCAGTACTGGGGCAAACCGCAGAAAACCCGCGACCTGGTGTTCGC
CATCGTCGCCGACCCGCAGGTGCGCATCCAGAAACTAAAGGCCGGCGAATGCCAGGTCGCCGCGGCGGTGCGCGAGTCCG
ACCTCGACTCGCTAAGCGGAGATAAAAACATCAAGATCGCCTCCACCGGCGCCAGCAACATCTCCTACCTCGCCTACAAT
CTGAAACGGCCGCAGTTCGCCAAGCGCGAGGTGCGGGTGGCGCTGGACATCGCGATCAACCGCGACGCGCTGTTCAAGGC
GCTGTTCCCCAAGGGCGGCGCGACGCAGGCGGTGAACCCGTTTCCGCCGTCCACCTGGAGCTGGAACCCGCGCACCCGCA
ACGAATACGATCCGGCCAAGGCCAAGGCGCTGCTGGCCAAGGCCGGCTATCCCGATGGCTTCACCGTCAACCTGTGGGCT
TTGCCGGTGCAGCGCCCGACCAATCCCAACGGCAAGCTGATGGCGCAGATGATCCAGCAGGACTGGGCCCGGATAGGGGT
CAAGGCCAATATCCAGTCCTATGAATGGGGCGAGTACCTGAAGCGGGCCGGCGCCGGCGAGCACGATGTCTACATGTCCG
GCCTGACCAGCAACTCCGGCGACCCGGACGACTTCCTCTGGAACAGTCTGTCCTGCAGCGTCAGCAAGGGCGGCCAGCGC
TTCTGCAACGCCGAGTTCGAACGGCTGCTGCAACTGGGCCGCCAAACCACCGACCAGAAGCAGCGGACGCAGTACTACCT
GAAGGCTCAGGAAATCTTCAAGCGCGAGCGCCCGTGGATCACCATCGCCCATTCGCGCATCTACATCCCGTTGCGCGCCA
ATGTGCAGGGCTTCATCATGAACCCCAACGGCTCTTTCGATTTCGAGGACGTATGGCTCAAGTGA

Upstream 100 bases:

>100_bases
GGTTTTCCAGCTCCTCGAGCCTGATCGTCCCCGTCATCGCCCCGCCTCCCGCTGATCTGAAACAAACCTGCCGCTCCCCC
CACTCGGTCGCGGACCCGGA

Downstream 100 bases:

>100_bases
ATCCGGCCTGGCCGCAGGCCTTCGCCTGCCACCGCTACCAGGCGCTGGCGAACGGTCCGGCGCTGATCGTCACCGGCGCG
GTGCATGGCAATGAAGTCTG

Product: binding protein component of ABC dipeptide transporter

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MCDTLQAYRYRRAADRRRARTIRKTDMILSRSLRALSLSLALATALPALAAKPLVFCAEASPEGFDPAMWDSATTYNITK
PVFQGLVEFKRGGVALRPGLAESWSVSPDGLVYTFRLRRNVKFHQTAYFTPSRDFSADDAVFTVNRWIRPELPFNQALRT
PLTGPDGYGLAKLIDSVQKVDDHTVRIRLKERNATFLTFFAMGFAGMQSAEYADQLLKAGKPQQLNLLPIGTGPYRFKSY
AKDAIIRYEAHPQYWGKPQKTRDLVFAIVADPQVRIQKLKAGECQVAAAVRESDLDSLSGDKNIKIASTGASNISYLAYN
LKRPQFAKREVRVALDIAINRDALFKALFPKGGATQAVNPFPPSTWSWNPRTRNEYDPAKAKALLAKAGYPDGFTVNLWA
LPVQRPTNPNGKLMAQMIQQDWARIGVKANIQSYEWGEYLKRAGAGEHDVYMSGLTSNSGDPDDFLWNSLSCSVSKGGQR
FCNAEFERLLQLGRQTTDQKQRTQYYLKAQEIFKRERPWITIAHSRIYIPLRANVQGFIMNPNGSFDFEDVWLK

Sequences:

>Translated_554_residues
MCDTLQAYRYRRAADRRRARTIRKTDMILSRSLRALSLSLALATALPALAAKPLVFCAEASPEGFDPAMWDSATTYNITK
PVFQGLVEFKRGGVALRPGLAESWSVSPDGLVYTFRLRRNVKFHQTAYFTPSRDFSADDAVFTVNRWIRPELPFNQALRT
PLTGPDGYGLAKLIDSVQKVDDHTVRIRLKERNATFLTFFAMGFAGMQSAEYADQLLKAGKPQQLNLLPIGTGPYRFKSY
AKDAIIRYEAHPQYWGKPQKTRDLVFAIVADPQVRIQKLKAGECQVAAAVRESDLDSLSGDKNIKIASTGASNISYLAYN
LKRPQFAKREVRVALDIAINRDALFKALFPKGGATQAVNPFPPSTWSWNPRTRNEYDPAKAKALLAKAGYPDGFTVNLWA
LPVQRPTNPNGKLMAQMIQQDWARIGVKANIQSYEWGEYLKRAGAGEHDVYMSGLTSNSGDPDDFLWNSLSCSVSKGGQR
FCNAEFERLLQLGRQTTDQKQRTQYYLKAQEIFKRERPWITIAHSRIYIPLRANVQGFIMNPNGSFDFEDVWLK
>Mature_554_residues
MCDTLQAYRYRRAADRRRARTIRKTDMILSRSLRALSLSLALATALPALAAKPLVFCAEASPEGFDPAMWDSATTYNITK
PVFQGLVEFKRGGVALRPGLAESWSVSPDGLVYTFRLRRNVKFHQTAYFTPSRDFSADDAVFTVNRWIRPELPFNQALRT
PLTGPDGYGLAKLIDSVQKVDDHTVRIRLKERNATFLTFFAMGFAGMQSAEYADQLLKAGKPQQLNLLPIGTGPYRFKSY
AKDAIIRYEAHPQYWGKPQKTRDLVFAIVADPQVRIQKLKAGECQVAAAVRESDLDSLSGDKNIKIASTGASNISYLAYN
LKRPQFAKREVRVALDIAINRDALFKALFPKGGATQAVNPFPPSTWSWNPRTRNEYDPAKAKALLAKAGYPDGFTVNLWA
LPVQRPTNPNGKLMAQMIQQDWARIGVKANIQSYEWGEYLKRAGAGEHDVYMSGLTSNSGDPDDFLWNSLSCSVSKGGQR
FCNAEFERLLQLGRQTTDQKQRTQYYLKAQEIFKRERPWITIAHSRIYIPLRANVQGFIMNPNGSFDFEDVWLK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=539, Percent_Identity=42.8571428571429, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1787551, Length=505, Percent_Identity=31.4851485148515, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1787052, Length=538, Percent_Identity=28.8104089219331, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI1787762, Length=533, Percent_Identity=25.328330206379, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1787495, Length=521, Percent_Identity=24.9520153550864, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081878, Length=515, Percent_Identity=24.8543689320388, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789397, Length=558, Percent_Identity=23.4767025089606, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789887, Length=415, Percent_Identity=26.0240963855422, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62437; Mature: 62437

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDTLQAYRYRRAADRRRARTIRKTDMILSRSLRALSLSLALATALPALAAKPLVFCAEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SPEGFDPAMWDSATTYNITKPVFQGLVEFKRGGVALRPGLAESWSVSPDGLVYTFRLRRN
CCCCCCCHHCCCCCEECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEEEECC
VKFHQTAYFTPSRDFSADDAVFTVNRWIRPELPFNQALRTPLTGPDGYGLAKLIDSVQKV
CEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHC
DDHTVRIRLKERNATFLTFFAMGFAGMQSAEYADQLLKAGKPQQLNLLPIGTGPYRFKSY
CCCEEEEEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
AKDAIIRYEAHPQYWGKPQKTRDLVFAIVADPQVRIQKLKAGECQVAAAVRESDLDSLSG
HCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHCHHHCCC
DKNIKIASTGASNISYLAYNLKRPQFAKREVRVALDIAINRDALFKALFPKGGATQAVNP
CCCEEEEECCCCCEEEEEEECCCCCHHHHHEEEEEEEEECHHHHHHHHCCCCCCCCCCCC
FPPSTWSWNPRTRNEYDPAKAKALLAKAGYPDGFTVNLWALPVQRPTNPNGKLMAQMIQQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
DWARIGVKANIQSYEWGEYLKRAGAGEHDVYMSGLTSNSGDPDDFLWNSLSCSVSKGGQR
HHHHCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCEEECCCCCHH
FCNAEFERLLQLGRQTTDQKQRTQYYLKAQEIFKRERPWITIAHSRIYIPLRANVQGFIM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCEEEEE
NPNGSFDFEDVWLK
CCCCCCCHHCCCCC
>Mature Secondary Structure
MCDTLQAYRYRRAADRRRARTIRKTDMILSRSLRALSLSLALATALPALAAKPLVFCAEA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
SPEGFDPAMWDSATTYNITKPVFQGLVEFKRGGVALRPGLAESWSVSPDGLVYTFRLRRN
CCCCCCCHHCCCCCEECCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEEEECC
VKFHQTAYFTPSRDFSADDAVFTVNRWIRPELPFNQALRTPLTGPDGYGLAKLIDSVQKV
CEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHC
DDHTVRIRLKERNATFLTFFAMGFAGMQSAEYADQLLKAGKPQQLNLLPIGTGPYRFKSY
CCCEEEEEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHH
AKDAIIRYEAHPQYWGKPQKTRDLVFAIVADPQVRIQKLKAGECQVAAAVRESDLDSLSG
HCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHCHHHCCC
DKNIKIASTGASNISYLAYNLKRPQFAKREVRVALDIAINRDALFKALFPKGGATQAVNP
CCCEEEEECCCCCEEEEEEECCCCCHHHHHEEEEEEEEECHHHHHHHHCCCCCCCCCCCC
FPPSTWSWNPRTRNEYDPAKAKALLAKAGYPDGFTVNLWALPVQRPTNPNGKLMAQMIQQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHH
DWARIGVKANIQSYEWGEYLKRAGAGEHDVYMSGLTSNSGDPDDFLWNSLSCSVSKGGQR
HHHHCCEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCEEECCCCCHH
FCNAEFERLLQLGRQTTDQKQRTQYYLKAQEIFKRERPWITIAHSRIYIPLRANVQGFIM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCEEEEE
NPNGSFDFEDVWLK
CCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]