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The map label for this gene is hmuS [H]

Identifier: 34499352

GI number: 34499352

Start: 4206571

End: 4207605

Strand: Direct

Name: hmuS [H]

Synonym: CV_3897

Alternate gene names: 34499352

Gene position: 4206571-4207605 (Clockwise)

Preceding gene: 34499351

Following gene: 34499353

Centisome position: 88.54

GC content: 70.34

Gene sequence:

>1035_bases
ATGAGCCAGCTATGGGACCGCTACCAGGCGCTCAAAGCCAGCCAGCCCAAGCTGCGCGTCCGCGACGCCGCGATGGCGCT
GGGCGTCAGCGAATGCGAGCTGGTGGCCGCCGACCCGGCCGCCACCCCGCTGCAGCCGGAATGGCCGGCCATCCTCGCCG
CCTTGGCCCCGCTGGGCCGGGTGATGGCGTTGACGCGCAACCATGCCTGCGTCCATGAAACCAAGGGCGACTACGCCAAT
GTCGAAATCGACGGCAGGGTCGGCCTCGCCATCAACCCGGTGATAGACCTGCGCATCTTCCTGTTCCACTGGCGGCACGG
TTTCGCCGTGCGCGGCGAGACGCCGCGCGGCGTCCAGCGCAGCCTGCAGTTCTTCGACCGCCACGGAGAAGCCGTGCACA
AGGTCTATCTGACCGCCGACAGCGACGTCGCCGCCTTCGACGCGCTGGCCGCGCGTTTCGCCTCGACCCCGGCGGCGCTG
GAGCTGGAGCCGGTCGCCGCGGCCGCCGCCGAGCAACCCGACGACGCCATAGACCGCGCCGCGTTCCAGGCCGAGTGGCG
CAGCCTGAACGACGTGCACGCCTTCCACCCCTTCCTGCGCCGCTGGCAGGTATCGCGCCGCCAGGGCTTCCGGCTGGCGC
CGGCAGGCCAGGCCTGGCGCGTGCGCGAAGACGCGGTCGAGCAGTTGCTGCGCCGCGCCGCCGCCACCGAAACGCCGATC
ATGGTGTTCGCCGGCAACCGCGGCATGATCCAGATCCACACCGGCCCGGTGCGCAACATCCAGGTGGTCGGCGACTGGCT
GAACGTGCTGGACCCGGACTTCAACCTGCACCTGCGCACCGACCTGATCGCAGAAGCCTGGGTCACCCGCAAGCCCGGCG
ACAACGGCGTGGTCACCTCGCTGGAGTTGTTCGACGAGCAGGGCGAATCGCTGGCCACCTTCTTCGGCGAGCGCAAGCCG
GGCCGCCCGGAGCGGGCGGAATGGGTGAAGCTGCTGGGCGAGCTGCCGCTGCTGGAGAAAGCCGATGTCGCGTAA

Upstream 100 bases:

>100_bases
TACACCCAGCCCGGCCGCAACGTCAGCGCCAGCGTCGAATACCAATTCTGATCCACCCGGCGGGCGGCCTCCCGCCCGCC
GCCAACCACAGGAGAACACC

Downstream 100 bases:

>100_bases
AACCCTGCTGGCCGGCCTGCTGCTGGCCGCCCTGCCGCCGGCCGGCCTCGCCGCCGAGCGGCTGGTGGTGGTGACGCCCG
ACATCGCCGAGATCGTAGTC

Product: hemin degrading factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSQLWDRYQALKASQPKLRVRDAAMALGVSECELVAADPAATPLQPEWPAILAALAPLGRVMALTRNHACVHETKGDYAN
VEIDGRVGLAINPVIDLRIFLFHWRHGFAVRGETPRGVQRSLQFFDRHGEAVHKVYLTADSDVAAFDALAARFASTPAAL
ELEPVAAAAAEQPDDAIDRAAFQAEWRSLNDVHAFHPFLRRWQVSRRQGFRLAPAGQAWRVREDAVEQLLRRAAATETPI
MVFAGNRGMIQIHTGPVRNIQVVGDWLNVLDPDFNLHLRTDLIAEAWVTRKPGDNGVVTSLELFDEQGESLATFFGERKP
GRPERAEWVKLLGELPLLEKADVA

Sequences:

>Translated_344_residues
MSQLWDRYQALKASQPKLRVRDAAMALGVSECELVAADPAATPLQPEWPAILAALAPLGRVMALTRNHACVHETKGDYAN
VEIDGRVGLAINPVIDLRIFLFHWRHGFAVRGETPRGVQRSLQFFDRHGEAVHKVYLTADSDVAAFDALAARFASTPAAL
ELEPVAAAAAEQPDDAIDRAAFQAEWRSLNDVHAFHPFLRRWQVSRRQGFRLAPAGQAWRVREDAVEQLLRRAAATETPI
MVFAGNRGMIQIHTGPVRNIQVVGDWLNVLDPDFNLHLRTDLIAEAWVTRKPGDNGVVTSLELFDEQGESLATFFGERKP
GRPERAEWVKLLGELPLLEKADVA
>Mature_343_residues
SQLWDRYQALKASQPKLRVRDAAMALGVSECELVAADPAATPLQPEWPAILAALAPLGRVMALTRNHACVHETKGDYANV
EIDGRVGLAINPVIDLRIFLFHWRHGFAVRGETPRGVQRSLQFFDRHGEAVHKVYLTADSDVAAFDALAARFASTPAALE
LEPVAAAAAEQPDDAIDRAAFQAEWRSLNDVHAFHPFLRRWQVSRRQGFRLAPAGQAWRVREDAVEQLLRRAAATETPIM
VFAGNRGMIQIHTGPVRNIQVVGDWLNVLDPDFNLHLRTDLIAEAWVTRKPGDNGVVTSLELFDEQGESLATFFGERKPG
RPERAEWVKLLGELPLLEKADVA

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007845 [H]

Pfam domain/function: PF05171 HemS [H]

EC number: NA

Molecular weight: Translated: 38206; Mature: 38075

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLWDRYQALKASQPKLRVRDAAMALGVSECELVAADPAATPLQPEWPAILAALAPLGR
CCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
VMALTRNHACVHETKGDYANVEIDGRVGLAINPVIDLRIFLFHWRHGFAVRGETPRGVQR
HHHHHCCCCEEECCCCCEEEEEECCEECEEECCHHHHHHEEEECCCCEEEECCCCHHHHH
SLQFFDRHGEAVHKVYLTADSDVAAFDALAARFASTPAALELEPVAAAAAEQPDDAIDRA
HHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECHHHHHHCCCCHHHHHHH
AFQAEWRSLNDVHAFHPFLRRWQVSRRQGFRLAPAGQAWRVREDAVEQLLRRAAATETPI
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCE
MVFAGNRGMIQIHTGPVRNIQVVGDWLNVLDPDFNLHLRTDLIAEAWVTRKPGDNGVVTS
EEEECCCCEEEEECCCCCEEEEEEHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEE
LELFDEQGESLATFFGERKPGRPERAEWVKLLGELPLLEKADVA
HHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SQLWDRYQALKASQPKLRVRDAAMALGVSECELVAADPAATPLQPEWPAILAALAPLGR
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
VMALTRNHACVHETKGDYANVEIDGRVGLAINPVIDLRIFLFHWRHGFAVRGETPRGVQR
HHHHHCCCCEEECCCCCEEEEEECCEECEEECCHHHHHHEEEECCCCEEEECCCCHHHHH
SLQFFDRHGEAVHKVYLTADSDVAAFDALAARFASTPAALELEPVAAAAAEQPDDAIDRA
HHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEECHHHHHHCCCCHHHHHHH
AFQAEWRSLNDVHAFHPFLRRWQVSRRQGFRLAPAGQAWRVREDAVEQLLRRAAATETPI
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCE
MVFAGNRGMIQIHTGPVRNIQVVGDWLNVLDPDFNLHLRTDLIAEAWVTRKPGDNGVVTS
EEEECCCCEEEEECCCCCEEEEEEHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEE
LELFDEQGESLATFFGERKPGRPERAEWVKLLGELPLLEKADVA
HHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]