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The map label for this gene is prpC [H]

Identifier: 34499303

GI number: 34499303

Start: 4152829

End: 4153707

Strand: Reverse

Name: prpC [H]

Synonym: CV_3848

Alternate gene names: 34499303

Gene position: 4153707-4152829 (Counterclockwise)

Preceding gene: 34499304

Following gene: 34499302

Centisome position: 87.43

GC content: 65.64

Gene sequence:

>879_bases
ATGAAACTGTCCATCTTTCAGGAAAGCCGGATCGGCGGGCGCAGCTATAACCAGGACCGGCTGGCCATCGCCCATTCGCG
CGAGGCGGTGATGCTGGTGATGGCCGACGGCATGGGCGGGCACATGCGCGGCGAGGTGGCCGCCCAGATCACGGTGGACC
TGCTCAGCGAACTGTTCTACCAGCAGGCGACGCCTACGATCAGCCACCCCAACCGTTTCCTGGTGAACGCCATCAGTTCG
GTGCACCAAGTGATCCTGGAGTATGCGGCCGACCACCGGCTGCCCGATGTGCCGAGCACCACGGTGGTGGTGGCCATCCT
GCAGCACGGCCAGCTGTATTGGTGCCATGTCGGGGATTCGCGGCTGTACCTGCTCGACGGCGGCGGGCTGAGGCTTCGCT
CGCGCGACCATTCCCAGGTGCAGCGGCTGATAGACCAGGGCCTGCTGACCGAGGAGGGCGCCAAGACCCATCCCGAACGC
AACAAGATCTACAACTGCCTGGGCGCCGCGGGCGAGCCCGACATCGACATCGGCGAGCGGCAGGTAATCGGCCCGGGGTG
TTCCATTCTGTTGTGCACCGACGGCTTGTGGTCGCAAGTGCAGGACGCCGAGCTGGAAAAGGTGTTCGCCGGGCGCAGCG
TCAACCAGGTGATGCCGGCGCTGATCAATGTGGCGGAGCGGCGCGCCGGCAACGGCGGCGACAATCTGTCGGCGGTGGCG
GTGACGCTGCTGGAGGATAGCCTGGAGCTGGGCGAGCGCGACGACGTGCTGGATACCGAAAAGACGCCGCCGCAAAAGGC
CGGCCGGCTGATCCTGGAGTCCAACCTGGCGACCATGCACCAGGAAATCCTGGCCAGCCAGGTGGACAAGGACAGCTGA

Upstream 100 bases:

>100_bases
CGGAATACAGCCAGCCGGAACGCCCGCCTGCGGGAGAGGGCAGCCGCCTGGTCGGCTGGATCAAGGGGCTGGCCGGTGGC
CGGCATCGAGAGGGGTCGGA

Downstream 100 bases:

>100_bases
GCGCGGGCGGCTGTTATAATCGCCGTCGATCTTCTTTATCCCCAGGGCCATCATGCGACCTTCCCAACGTAGTGCCGACG
CGATGCGCGTCGTGCGTCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKLSIFQESRIGGRSYNQDRLAIAHSREAVMLVMADGMGGHMRGEVAAQITVDLLSELFYQQATPTISHPNRFLVNAISS
VHQVILEYAADHRLPDVPSTTVVVAILQHGQLYWCHVGDSRLYLLDGGGLRLRSRDHSQVQRLIDQGLLTEEGAKTHPER
NKIYNCLGAAGEPDIDIGERQVIGPGCSILLCTDGLWSQVQDAELEKVFAGRSVNQVMPALINVAERRAGNGGDNLSAVA
VTLLEDSLELGERDDVLDTEKTPPQKAGRLILESNLATMHQEILASQVDKDS

Sequences:

>Translated_292_residues
MKLSIFQESRIGGRSYNQDRLAIAHSREAVMLVMADGMGGHMRGEVAAQITVDLLSELFYQQATPTISHPNRFLVNAISS
VHQVILEYAADHRLPDVPSTTVVVAILQHGQLYWCHVGDSRLYLLDGGGLRLRSRDHSQVQRLIDQGLLTEEGAKTHPER
NKIYNCLGAAGEPDIDIGERQVIGPGCSILLCTDGLWSQVQDAELEKVFAGRSVNQVMPALINVAERRAGNGGDNLSAVA
VTLLEDSLELGERDDVLDTEKTPPQKAGRLILESNLATMHQEILASQVDKDS
>Mature_292_residues
MKLSIFQESRIGGRSYNQDRLAIAHSREAVMLVMADGMGGHMRGEVAAQITVDLLSELFYQQATPTISHPNRFLVNAISS
VHQVILEYAADHRLPDVPSTTVVVAILQHGQLYWCHVGDSRLYLLDGGGLRLRSRDHSQVQRLIDQGLLTEEGAKTHPER
NKIYNCLGAAGEPDIDIGERQVIGPGCSILLCTDGLWSQVQDAELEKVFAGRSVNQVMPALINVAERRAGNGGDNLSAVA
VTLLEDSLELGERDDVLDTEKTPPQKAGRLILESNLATMHQEILASQVDKDS

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 31951; Mature: 31951

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSIFQESRIGGRSYNQDRLAIAHSREAVMLVMADGMGGHMRGEVAAQITVDLLSELFY
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
QQATPTISHPNRFLVNAISSVHQVILEYAADHRLPDVPSTTVVVAILQHGQLYWCHVGDS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCC
RLYLLDGGGLRLRSRDHSQVQRLIDQGLLTEEGAKTHPERNKIYNCLGAAGEPDIDIGER
EEEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCE
QVIGPGCSILLCTDGLWSQVQDAELEKVFAGRSVNQVMPALINVAERRAGNGGDNLSAVA
EEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTLLEDSLELGERDDVLDTEKTPPQKAGRLILESNLATMHQEILASQVDKDS
HHHHHHHHHCCCCCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLSIFQESRIGGRSYNQDRLAIAHSREAVMLVMADGMGGHMRGEVAAQITVDLLSELFY
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
QQATPTISHPNRFLVNAISSVHQVILEYAADHRLPDVPSTTVVVAILQHGQLYWCHVGDS
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCC
RLYLLDGGGLRLRSRDHSQVQRLIDQGLLTEEGAKTHPERNKIYNCLGAAGEPDIDIGER
EEEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCE
QVIGPGCSILLCTDGLWSQVQDAELEKVFAGRSVNQVMPALINVAERRAGNGGDNLSAVA
EEECCCCEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
VTLLEDSLELGERDDVLDTEKTPPQKAGRLILESNLATMHQEILASQVDKDS
HHHHHHHHHCCCCCCCCCCCCCCHHHHCCEEEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]