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The map label for this gene is modB [H]

Identifier: 34499182

GI number: 34499182

Start: 4024767

End: 4025441

Strand: Direct

Name: modB [H]

Synonym: CV_3727

Alternate gene names: 34499182

Gene position: 4024767-4025441 (Clockwise)

Preceding gene: 34499181

Following gene: 34499183

Centisome position: 84.71

GC content: 67.11

Gene sequence:

>675_bases
GTGAGCCCGCAGGACTGGAGCGCGATCGCGCTGACCCTGCGCCTGGCCGGCATCAGCACGCTGCTGCTGCTGGCCCTGTG
CATTCCCTGCGCCTGGTGGCTGGCGCACAGCCGCTCCCGGCTGCGCCCCATCATGGAAGCCGGCGCCATGCTGCCGCTGG
TGCTGCCGCCGACGGTGCTGGGCTTCTATCTGCTGCTGGCCTTCGGACCGCACGGGCCGGTCGGCAAACTGACATCCTCG
CTGGGTTTGCCGGGCCTCGCCTTCACCTTCCCCGGCGTGGTGCTCGCCTCCATCCTGTACTCGCTTCCCTTCGTGTTGCA
GCCTTTGCTGGCCAGCTTCCGCGCGGTGCGGCAGGAAGAGCTGGAAAGCGCGCGGCTGCTGGGCGCCGGACGCTGGCAGC
GGATGCGCCACGTGATCCTGCCTTCCTGCCGCAGCGGCCTGCTCAGCGCGGCCTGCCTGGGCTTCGCCCATACGGTAGGC
GAGTTCGGCGTGGTGCTGATGATAGGCGGCAATATCGACGGCGAAACGCGCGTGATATCGATCGCGCTGTACAATCAGGT
GGAGCAGGCCAACTACGGCGCCGCCCACCAGCTGGCGCTGATGTTGCTGCTGTTTTCACTGGCGGCGTTGAGCGCCGTTT
ATTGGCTGAACGCCCGACAGAAACAATCCGAATGA

Upstream 100 bases:

>100_bases
TGCTGATCAAGCCGACGCCGGCCGCGGCCGCGCTGATGGCCTACCTCAAGGGCGAGCAGGCGCGCGCGCTGATGGCCCAG
GCAGGCTACCGCTTCAAGCC

Downstream 100 bases:

>100_bases
CATCCGCCCGCGCCGCGGGCGCCACACTGGAGACATCCACCATGCGCAAATCCGTGCTGCTCGCCGTACTCGCCCTGTTC
AGCGCCAACCTGGCGCTGGC

Product: molybdate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSPQDWSAIALTLRLAGISTLLLLALCIPCAWWLAHSRSRLRPIMEAGAMLPLVLPPTVLGFYLLLAFGPHGPVGKLTSS
LGLPGLAFTFPGVVLASILYSLPFVLQPLLASFRAVRQEELESARLLGAGRWQRMRHVILPSCRSGLLSAACLGFAHTVG
EFGVVLMIGGNIDGETRVISIALYNQVEQANYGAAHQLALMLLLFSLAALSAVYWLNARQKQSE

Sequences:

>Translated_224_residues
MSPQDWSAIALTLRLAGISTLLLLALCIPCAWWLAHSRSRLRPIMEAGAMLPLVLPPTVLGFYLLLAFGPHGPVGKLTSS
LGLPGLAFTFPGVVLASILYSLPFVLQPLLASFRAVRQEELESARLLGAGRWQRMRHVILPSCRSGLLSAACLGFAHTVG
EFGVVLMIGGNIDGETRVISIALYNQVEQANYGAAHQLALMLLLFSLAALSAVYWLNARQKQSE
>Mature_223_residues
SPQDWSAIALTLRLAGISTLLLLALCIPCAWWLAHSRSRLRPIMEAGAMLPLVLPPTVLGFYLLLAFGPHGPVGKLTSSL
GLPGLAFTFPGVVLASILYSLPFVLQPLLASFRAVRQEELESARLLGAGRWQRMRHVILPSCRSGLLSAACLGFAHTVGE
FGVVLMIGGNIDGETRVISIALYNQVEQANYGAAHQLALMLLLFSLAALSAVYWLNARQKQSE

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=230, Percent_Identity=32.1739130434783, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788764, Length=198, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786980, Length=224, Percent_Identity=29.9107142857143, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1787369, Length=231, Percent_Identity=25.5411255411255, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24174; Mature: 24043

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPQDWSAIALTLRLAGISTLLLLALCIPCAWWLAHSRSRLRPIMEAGAMLPLVLPPTVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHH
GFYLLLAFGPHGPVGKLTSSLGLPGLAFTFPGVVLASILYSLPFVLQPLLASFRAVRQEE
HHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESARLLGAGRWQRMRHVILPSCRSGLLSAACLGFAHTVGEFGVVLMIGGNIDGETRVIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEE
IALYNQVEQANYGAAHQLALMLLLFSLAALSAVYWLNARQKQSE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SPQDWSAIALTLRLAGISTLLLLALCIPCAWWLAHSRSRLRPIMEAGAMLPLVLPPTVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHH
GFYLLLAFGPHGPVGKLTSSLGLPGLAFTFPGVVLASILYSLPFVLQPLLASFRAVRQEE
HHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LESARLLGAGRWQRMRHVILPSCRSGLLSAACLGFAHTVGEFGVVLMIGGNIDGETRVIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEE
IALYNQVEQANYGAAHQLALMLLLFSLAALSAVYWLNARQKQSE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8384683; 7665518 [H]