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The map label for this gene is trpS2 [H]

Identifier: 34499170

GI number: 34499170

Start: 4016162

End: 4017184

Strand: Direct

Name: trpS2 [H]

Synonym: CV_3715

Alternate gene names: 34499170

Gene position: 4016162-4017184 (Clockwise)

Preceding gene: 34499169

Following gene: 34499171

Centisome position: 84.53

GC content: 65.4

Gene sequence:

>1023_bases
ATGAATCTGGACACGATCAGCTCGCAAGACATCATCCTCACCGGCGACCGCACCACCGGCCAGCTGCACCTCGGCCATTA
CGTCGGCTCGCTGCGCAACCGCGTGATCCTGCAGGAGCGCTGCGCGCAATTCCTGCTGCTAGCCGACGCCCAGGCGCTGA
CCGACAATATGGGCAACTACCTGAAGGTGCGCGACAACGTGCTGCAGGTGGCGCTGGACTACCTGGCCGTCGGCATCGAC
CCGGCCAAGAGCACCATCTTCATCCAGAGCCTGGTGCCGGAGCTGACCGAGCTGGCCTCCTACTATCTCAACCTGGTGAC
GGTGGCCCGGCTGGAGCGCAATCCGACCATCAAGGACGAGATCAAGCAGCGCGGCTACGAGCGCGACATCCCGGCCGGCT
TCCTCACCTACCCGGCCGCCCAGGCGGCGGACATCACCGCGTTCAAGGCCACCATCGTGCCGGTAGGCGACGACCAGATC
CCGATGATCGAGCAGACCAACGAGATCGTGCGCCGCTTCAACGCCAGCGTAGACCAGCCGGTGCTGGTGGAAACCAGGGC
GGTGGTGCCGGAAGTGGGCTCCCGCCTGCCCGGCATTGACGGCAAGGCCAAGATGTCCAAATCGCTGGGCAATACCATCA
CGCTGTCGGCGTCCCCCGACGACATCCGCCAGGCGGTGAAGATGATGTACACCGATCCCACCCATCTGCGCGTGGCCGAT
CCCGGCCAGGTGGAGGGCAATGTGGTGTTCACCTACCTAGACGCCTTCCACCCCGACCGCGAGCTGGTGCAAGGCCTGAA
GGACCACTACCGCCGCGGCGGCCTGGGCGACACCGTGATCAAGAAGCATCTGGAAGACTGCCTGCAGGAGATGCTGGCGC
CGATACGCGCGCGCCGCGAGCACTACGCCCAGGATCCGTCGGCGGTATTGGAGATGCTGAAAACCGGCACCCGCCGCGCC
CGCGACGTCGCCGCCCGCACGCTGTCCGAAGTGAAGGCGGCGATGGGCCTGAACTATTACTGA

Upstream 100 bases:

>100_bases
GAACCCGGAGGCTGCCGACAAGGCGCACCGGGTTTTGTTTTTGGCGGTTCCTCCCAGTCCACCTTGCCGGCCTCCTCTCC
AACCCGATGGAGATATCGAC

Downstream 100 bases:

>100_bases
GCGGGAGCCCGGCATGGAACACGTCTACCCATGCCAAAACCTCGCAGAAACGCGCGCGCAGACGACCGCATCGACCGCGC
GCTGGTGGCGCTGATCGCCG

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MNLDTISSQDIILTGDRTTGQLHLGHYVGSLRNRVILQERCAQFLLLADAQALTDNMGNYLKVRDNVLQVALDYLAVGID
PAKSTIFIQSLVPELTELASYYLNLVTVARLERNPTIKDEIKQRGYERDIPAGFLTYPAAQAADITAFKATIVPVGDDQI
PMIEQTNEIVRRFNASVDQPVLVETRAVVPEVGSRLPGIDGKAKMSKSLGNTITLSASPDDIRQAVKMMYTDPTHLRVAD
PGQVEGNVVFTYLDAFHPDRELVQGLKDHYRRGGLGDTVIKKHLEDCLQEMLAPIRARREHYAQDPSAVLEMLKTGTRRA
RDVAARTLSEVKAAMGLNYY

Sequences:

>Translated_340_residues
MNLDTISSQDIILTGDRTTGQLHLGHYVGSLRNRVILQERCAQFLLLADAQALTDNMGNYLKVRDNVLQVALDYLAVGID
PAKSTIFIQSLVPELTELASYYLNLVTVARLERNPTIKDEIKQRGYERDIPAGFLTYPAAQAADITAFKATIVPVGDDQI
PMIEQTNEIVRRFNASVDQPVLVETRAVVPEVGSRLPGIDGKAKMSKSLGNTITLSASPDDIRQAVKMMYTDPTHLRVAD
PGQVEGNVVFTYLDAFHPDRELVQGLKDHYRRGGLGDTVIKKHLEDCLQEMLAPIRARREHYAQDPSAVLEMLKTGTRRA
RDVAARTLSEVKAAMGLNYY
>Mature_340_residues
MNLDTISSQDIILTGDRTTGQLHLGHYVGSLRNRVILQERCAQFLLLADAQALTDNMGNYLKVRDNVLQVALDYLAVGID
PAKSTIFIQSLVPELTELASYYLNLVTVARLERNPTIKDEIKQRGYERDIPAGFLTYPAAQAADITAFKATIVPVGDDQI
PMIEQTNEIVRRFNASVDQPVLVETRAVVPEVGSRLPGIDGKAKMSKSLGNTITLSASPDDIRQAVKMMYTDPTHLRVAD
PGQVEGNVVFTYLDAFHPDRELVQGLKDHYRRGGLGDTVIKKHLEDCLQEMLAPIRARREHYAQDPSAVLEMLKTGTRRA
RDVAARTLSEVKAAMGLNYY

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=339, Percent_Identity=30.3834808259587, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI41352700, Length=168, Percent_Identity=34.5238095238095, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789786, Length=338, Percent_Identity=30.1775147928994, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71982800, Length=347, Percent_Identity=27.6657060518732, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71982793, Length=347, Percent_Identity=27.6657060518732, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320474, Length=356, Percent_Identity=26.9662921348315, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24666151, Length=332, Percent_Identity=33.433734939759, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37748; Mature: 37748

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDTISSQDIILTGDRTTGQLHLGHYVGSLRNRVILQERCAQFLLLADAQALTDNMGNY
CCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LKVRDNVLQVALDYLAVGIDPAKSTIFIQSLVPELTELASYYLNLVTVARLERNPTIKDE
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IKQRGYERDIPAGFLTYPAAQAADITAFKATIVPVGDDQIPMIEQTNEIVRRFNASVDQP
HHHCCCCCCCCCCHHHCCCCHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
VLVETRAVVPEVGSRLPGIDGKAKMSKSLGNTITLSASPDDIRQAVKMMYTDPTHLRVAD
EEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEECC
PGQVEGNVVFTYLDAFHPDRELVQGLKDHYRRGGLGDTVIKKHLEDCLQEMLAPIRARRE
CCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HYAQDPSAVLEMLKTGTRRARDVAARTLSEVKAAMGLNYY
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLDTISSQDIILTGDRTTGQLHLGHYVGSLRNRVILQERCAQFLLLADAQALTDNMGNY
CCCCCCCCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LKVRDNVLQVALDYLAVGIDPAKSTIFIQSLVPELTELASYYLNLVTVARLERNPTIKDE
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IKQRGYERDIPAGFLTYPAAQAADITAFKATIVPVGDDQIPMIEQTNEIVRRFNASVDQP
HHHCCCCCCCCCCHHHCCCCHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
VLVETRAVVPEVGSRLPGIDGKAKMSKSLGNTITLSASPDDIRQAVKMMYTDPTHLRVAD
EEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCEEEECC
PGQVEGNVVFTYLDAFHPDRELVQGLKDHYRRGGLGDTVIKKHLEDCLQEMLAPIRARRE
CCCCCCCEEEEEEHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HYAQDPSAVLEMLKTGTRRARDVAARTLSEVKAAMGLNYY
HHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA