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The map label for this gene is cioA [H]

Identifier: 34499113

GI number: 34499113

Start: 3957432

End: 3958778

Strand: Reverse

Name: cioA [H]

Synonym: CV_3658

Alternate gene names: 34499113

Gene position: 3958778-3957432 (Counterclockwise)

Preceding gene: 34499114

Following gene: 34499112

Centisome position: 83.32

GC content: 65.33

Gene sequence:

>1347_bases
ATGATGACCGAACTCGACCCCGTCACGCTGGCGCGCATCCAGTTCGCCACCAATATCAGCTTTCACATCCTGTTTCCCAC
CATCAATATCGCGATGGCCTGGGTGCTGCTGTTCTTCAAGCTGCGCTTCCGCCAGAGCGGCGACCAGGGCTGGATGGACG
CCTATGGCTTCTGGGTGAAGATCTTCGCGCTGTCATTCGCGCTGGGCGTGGTGTCCGGCGTGACGATGAGCTTCCAGTTC
GGCACCAACTGGCCCGGCTACATGCAGACGGTGGGCAATATCGCCGGCCCGCTGCTGGCCTACGAGATCCTGACCGCCTT
CTTCCTGGAGGCCGGCTTCCTCGGCATCATGCTGTTCGGCCGCTCGCGGGTACCGGAAAAGGTGCACACGCTGGCGACTT
TCCTGGTGGCTTTCGGCAACACCGTGTCGGCATTCTGGATCATCGCGCTCAACTCCTGGATGCAGACGCCGACCGGCCAC
GTGATGCGCGACGGCCGCGCCCACGTGCTGAGCTGGTGGGAGGTGATCTTCAATCCGTCGATGCCGTACCGGCTGACCCA
CATGCTGATCGCTTCCGGCCTGACCGTGGCCTTCCTGGTGGCTGGCCTGTCCGCCTACCGTTACCTGCGCGGCGAGCGCG
GCCGCGGCGTGATGGCGGCCTTGAAGACCGGCGTGTTCCTGGCCGCGCTGCTGATTCCGCTGCAGATCTTCGTCGGCGAC
ATGCATGGCCTCAACACGTTGAAGCACCAGCCGGCCAAGCTGGCGGCGATAGAGGGCATCTGGCACACCGAGAAGGACGT
GCCGCTGCTGCTGTTCGCGCTGCCCAACGCCGAAACCCGCAGCAACGACTACGCGATCGGCGTGCCGCAACTGGGCAGCC
TGATCCTCACCCACACCTGGGGCGGCGAAATCAAGGGCCTCAACGAGTTCGCACAGCATCCGCCGGTGGCCAAGGTGTTC
TGGAGCTTCCGCGTGATGGTGGGCATGGGCATGCTGATGCTGCTGGCGTCCTGGCTGGGCGCATGGCAGTTGAAACGGCG
CGGCGAGGTGTCGCGCGGCCTGGCCAGGCTGCTGGTGTGGATGACCTTCTCCGGCTGGATCGCCACGCTGGCCGGCTGGT
TCGTCACCGAGATCGGCCGCCAGCCCTGGCTGGTGACCGGCATCCTCACCACCGCGCAGGCGGCGGGGCCGGCCACCGCG
CCGATGCTGTTCACCTCGCTGAGCACTTATCTCGCGCTGTACGCGCTGCTGCTGCTGGCTTACGTCTCGGTGCTGTTCCA
CCTGGCGCGCAAGGCCGGCTCGCATGAACTGGCCGCCAACGCCCAACTGAAGGAGAAACTGGCATGA

Upstream 100 bases:

>100_bases
AGCGGCTGATGAAGCTGGGCTCGCAGGTGCAGAAAGTGCTGCAGTTCACCCAGTCGCTGTCCCGGCTGGGCAACCGCGAT
CAAGACCGGGAGCACGCAGA

Downstream 100 bases:

>100_bases
GCGAGGCTTACTACCTGCCGGCGGTGTTCGCCGGACTGATGGCGCTGGCGATGCTGGTGTATGTGGTGCTGGACGGCTTC
GACCTCGGCGTCGGCATCCT

Product: cyanide insensitive terminal oxidase

Products: NA

Alternate protein names: Cytochrome d ubiquinol oxidase subunit I [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MMTELDPVTLARIQFATNISFHILFPTINIAMAWVLLFFKLRFRQSGDQGWMDAYGFWVKIFALSFALGVVSGVTMSFQF
GTNWPGYMQTVGNIAGPLLAYEILTAFFLEAGFLGIMLFGRSRVPEKVHTLATFLVAFGNTVSAFWIIALNSWMQTPTGH
VMRDGRAHVLSWWEVIFNPSMPYRLTHMLIASGLTVAFLVAGLSAYRYLRGERGRGVMAALKTGVFLAALLIPLQIFVGD
MHGLNTLKHQPAKLAAIEGIWHTEKDVPLLLFALPNAETRSNDYAIGVPQLGSLILTHTWGGEIKGLNEFAQHPPVAKVF
WSFRVMVGMGMLMLLASWLGAWQLKRRGEVSRGLARLLVWMTFSGWIATLAGWFVTEIGRQPWLVTGILTTAQAAGPATA
PMLFTSLSTYLALYALLLLAYVSVLFHLARKAGSHELAANAQLKEKLA

Sequences:

>Translated_448_residues
MMTELDPVTLARIQFATNISFHILFPTINIAMAWVLLFFKLRFRQSGDQGWMDAYGFWVKIFALSFALGVVSGVTMSFQF
GTNWPGYMQTVGNIAGPLLAYEILTAFFLEAGFLGIMLFGRSRVPEKVHTLATFLVAFGNTVSAFWIIALNSWMQTPTGH
VMRDGRAHVLSWWEVIFNPSMPYRLTHMLIASGLTVAFLVAGLSAYRYLRGERGRGVMAALKTGVFLAALLIPLQIFVGD
MHGLNTLKHQPAKLAAIEGIWHTEKDVPLLLFALPNAETRSNDYAIGVPQLGSLILTHTWGGEIKGLNEFAQHPPVAKVF
WSFRVMVGMGMLMLLASWLGAWQLKRRGEVSRGLARLLVWMTFSGWIATLAGWFVTEIGRQPWLVTGILTTAQAAGPATA
PMLFTSLSTYLALYALLLLAYVSVLFHLARKAGSHELAANAQLKEKLA
>Mature_448_residues
MMTELDPVTLARIQFATNISFHILFPTINIAMAWVLLFFKLRFRQSGDQGWMDAYGFWVKIFALSFALGVVSGVTMSFQF
GTNWPGYMQTVGNIAGPLLAYEILTAFFLEAGFLGIMLFGRSRVPEKVHTLATFLVAFGNTVSAFWIIALNSWMQTPTGH
VMRDGRAHVLSWWEVIFNPSMPYRLTHMLIASGLTVAFLVAGLSAYRYLRGERGRGVMAALKTGVFLAALLIPLQIFVGD
MHGLNTLKHQPAKLAAIEGIWHTEKDVPLLLFALPNAETRSNDYAIGVPQLGSLILTHTWGGEIKGLNEFAQHPPVAKVF
WSFRVMVGMGMLMLLASWLGAWQLKRRGEVSRGLARLLVWMTFSGWIATLAGWFVTEIGRQPWLVTGILTTAQAAGPATA
PMLFTSLSTYLALYALLLLAYVSVLFHLARKAGSHELAANAQLKEKLA

Specific function: Cytochrome Oxidase Subunit. [C]

COG id: COG1271

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome ubiquinol oxidase subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1787212, Length=496, Percent_Identity=31.8548387096774, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI87081779, Length=319, Percent_Identity=35.7366771159875, Blast_Score=188, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002585 [H]

Pfam domain/function: PF01654 Bac_Ubq_Cox [H]

EC number: 1.10.3.-

Molecular weight: Translated: 49587; Mature: 49587

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCHHHCCHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHCCCCHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]