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The map label for this gene is ubiA [H]

Identifier: 34499063

GI number: 34499063

Start: 3914085

End: 3915557

Strand: Direct

Name: ubiA [H]

Synonym: CV_3608

Alternate gene names: 34499063

Gene position: 3914085-3915557 (Clockwise)

Preceding gene: 34499059

Following gene: 34499064

Centisome position: 82.38

GC content: 69.18

Gene sequence:

>1473_bases
ATGATAACGGCAAGTCGCCGCCTCCGGGTATCGCCGCAGGCGACAAGCGCCGCCGGCTTTTGGCATAATGCGCGCCATGG
TAAACGATGTCCTGTGGCGCGCCGCGCCCCCCGCCCTGCCCGACTCCATGCTGGATTGCCTGACCGAGCCCGCCTCGCTG
AGCCTGAGGCTGCAGGCGGGCGGCCGCCGTTTCGCGGTGTCCGTGCTGAGCCAGGGCGAAGACCGCGTGCTGGCCGACGA
GGCCGAGGCGCTGGGCCTGCCGGAAGGCCAGCCTATGTACGCCCGCCACGTGCTGCTGACCCTGGACGACATGCCGGTGG
TGTACGCCCGCAGCGCCGCCCGCCCCGACTGTCCGGCCTGGCTGCCGGTGCTGCGGCGCGGCAGCCGCTCGCTGGGCCTG
ACGCTGTTCGGCGAGCTGCCCGAGCTGGACCGCGAGCCGCTGCGCTACGGATGGCTGGCCGACGGCCATCCGCTGGCCGC
CGCCGCCACCCGGGTCCAGCCCGCGGCCGGCTATCCGGCCCGCCGCTGCCGCTTTCTGCTGGGCGGCTCGCCGCTGCTGC
TGACCGAGCTGTTCCTGCCCGCGCTGGAGGATTTCCTGTGATTTCGACCGCCACCATCCGCGACCGCTACGAAAACTATC
GGCAACTGATGCGCTGGGACAAGCCGATCGGCACTCTGCTGCTGCTGTGGCCGACGCTGTGGGCGCTGTGGATCGCCACC
CATGGCGCGCCCCGCCTGTCCATCGTCGCCATCTTCTGCCTGGGCACCTTCCTGATGCGCTCGGCCGGCTGCGTGATCAA
CGATTACGCCGACCGCGACTACGACGCCCACGTCGCGCGCACCAGCCAGCGCCCGTTCGCGCGCGGCGCGGTCAGCAAGA
AGGAGGCGCTGCTGCTGGCCGCCCTGCTGGCCGCCCTCTCCTTCCTGCTGGTGCTGCCGCTGAACAATCTGACCAAGCTG
CTGAGCGTGCCGGCGGTGCTGATCGCGGCCAGTTACCCGTTCACCAAGCGCTTCTTCCCGATGCCGCAGGCCTACCTGGG
CGTCGCCTTCTCCTTCGGCATCCCGATGGGCTTCGCCGCCGAAACCGGCGAAGTACCCGTTCTGGCCTGGCTGCTGCTGC
TGGCCAACCTGTTCTGGGTGGTGGCCTACGACACCGCCTACGCGATTGCGGACAAGCCGGACGATCTGAAGATCGGCATC
AAGACTTCGGCCATCACCATGGGCGACTACGACGTCGCCGGCGTGATGCTGTGCCATGCCGCCTTCCTCGCCCTGATGTG
CGGAATAGGCGTGCATCTGGCGCTGGCCTGGCCCTACTACCTGGGCCTCGCTGCCGCGGCCGCGCTGATCATGCAGCAAT
ACCGCGAGATCAAGGACCGCGACCGCGCCAAGTGCTTCAAGGCCTTTCTCGACAACAACCGTGTCGGCGCGGCCGTGTTC
GCCGGCGTGCTGCTCAGCTACTGGCTGAGCTGA

Upstream 100 bases:

>100_bases
CCAGCCCATGCCGCGCACCAGCGCCTCTCCCGCCAGCTGGTAGCCCAGCAGCCACAACAGCAGATCCAGCATATGCCCTC
CCGTCCAACGCGCTCTGGGC

Downstream 100 bases:

>100_bases
GACCTGACCCATATGCCATTTACAATAAATTACGCATGCGTCAGCATTCTGGGATGAACTTCGCCCGCCGGCGCGGCTCA
TAGCAAGGCCGGGCCGCGGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MITASRRLRVSPQATSAAGFWHNARHGKRCPVARRAPRPARLHAGLPDRARLAEPEAAGGRPPFRGVRAEPGRRPRAGRR
GRGAGPAGRPAYVRPPRAADPGRHAGGVRPQRRPPRLSGLAAGAAARQPLAGPDAVRRAARAGPRAAALRMAGRRPSAGR
RRHPGPARGRLSGPPLPLSAGRLAAAADRAVPARAGGFPVISTATIRDRYENYRQLMRWDKPIGTLLLLWPTLWALWIAT
HGAPRLSIVAIFCLGTFLMRSAGCVINDYADRDYDAHVARTSQRPFARGAVSKKEALLLAALLAALSFLLVLPLNNLTKL
LSVPAVLIAASYPFTKRFFPMPQAYLGVAFSFGIPMGFAAETGEVPVLAWLLLLANLFWVVAYDTAYAIADKPDDLKIGI
KTSAITMGDYDVAGVMLCHAAFLALMCGIGVHLALAWPYYLGLAAAAALIMQQYREIKDRDRAKCFKAFLDNNRVGAAVF
AGVLLSYWLS

Sequences:

>Translated_490_residues
MITASRRLRVSPQATSAAGFWHNARHGKRCPVARRAPRPARLHAGLPDRARLAEPEAAGGRPPFRGVRAEPGRRPRAGRR
GRGAGPAGRPAYVRPPRAADPGRHAGGVRPQRRPPRLSGLAAGAAARQPLAGPDAVRRAARAGPRAAALRMAGRRPSAGR
RRHPGPARGRLSGPPLPLSAGRLAAAADRAVPARAGGFPVISTATIRDRYENYRQLMRWDKPIGTLLLLWPTLWALWIAT
HGAPRLSIVAIFCLGTFLMRSAGCVINDYADRDYDAHVARTSQRPFARGAVSKKEALLLAALLAALSFLLVLPLNNLTKL
LSVPAVLIAASYPFTKRFFPMPQAYLGVAFSFGIPMGFAAETGEVPVLAWLLLLANLFWVVAYDTAYAIADKPDDLKIGI
KTSAITMGDYDVAGVMLCHAAFLALMCGIGVHLALAWPYYLGLAAAAALIMQQYREIKDRDRAKCFKAFLDNNRVGAAVF
AGVLLSYWLS
>Mature_490_residues
MITASRRLRVSPQATSAAGFWHNARHGKRCPVARRAPRPARLHAGLPDRARLAEPEAAGGRPPFRGVRAEPGRRPRAGRR
GRGAGPAGRPAYVRPPRAADPGRHAGGVRPQRRPPRLSGLAAGAAARQPLAGPDAVRRAARAGPRAAALRMAGRRPSAGR
RRHPGPARGRLSGPPLPLSAGRLAAAADRAVPARAGGFPVISTATIRDRYENYRQLMRWDKPIGTLLLLWPTLWALWIAT
HGAPRLSIVAIFCLGTFLMRSAGCVINDYADRDYDAHVARTSQRPFARGAVSKKEALLLAALLAALSFLLVLPLNNLTKL
LSVPAVLIAASYPFTKRFFPMPQAYLGVAFSFGIPMGFAAETGEVPVLAWLLLLANLFWVVAYDTAYAIADKPDDLKIGI
KTSAITMGDYDVAGVMLCHAAFLALMCGIGVHLALAWPYYLGLAAAAALIMQQYREIKDRDRAKCFKAFLDNNRVGAAVF
AGVLLSYWLS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=276, Percent_Identity=34.0579710144928, Blast_Score=163, Evalue=4e-40,
Organism=Escherichia coli, GI1790473, Length=282, Percent_Identity=52.1276595744681, Blast_Score=288, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17553718, Length=277, Percent_Identity=36.8231046931408, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI32565247, Length=278, Percent_Identity=35.6115107913669, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17553720, Length=335, Percent_Identity=30.7462686567164, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=44.5255474452555, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32565243, Length=136, Percent_Identity=44.1176470588235, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=282, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21355567, Length=276, Percent_Identity=36.231884057971, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 52770; Mature: 52770

Theoretical pI: Translated: 11.91; Mature: 11.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITASRRLRVSPQATSAAGFWHNARHGKRCPVARRAPRPARLHAGLPDRARLAEPEAAGG
CCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCCCCCCCC
RPPFRGVRAEPGRRPRAGRRGRGAGPAGRPAYVRPPRAADPGRHAGGVRPQRRPPRLSGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AAGAAARQPLAGPDAVRRAARAGPRAAALRMAGRRPSAGRRRHPGPARGRLSGPPLPLSA
HHCHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GRLAAAADRAVPARAGGFPVISTATIRDRYENYRQLMRWDKPIGTLLLLWPTLWALWIAT
CCHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HGAPRLSIVAIFCLGTFLMRSAGCVINDYADRDYDAHVARTSQRPFARGAVSKKEALLLA
CCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCCCHHHHCCCHHHHHHHH
ALLAALSFLLVLPLNNLTKLLSVPAVLIAASYPFTKRFFPMPQAYLGVAFSFGIPMGFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCC
ETGEVPVLAWLLLLANLFWVVAYDTAYAIADKPDDLKIGIKTSAITMGDYDVAGVMLCHA
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEEEECCCHHHHHHHHHH
AFLALMCGIGVHLALAWPYYLGLAAAAALIMQQYREIKDRDRAKCFKAFLDNNRVGAAVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AGVLLSYWLS
HHHHHHHHCC
>Mature Secondary Structure
MITASRRLRVSPQATSAAGFWHNARHGKRCPVARRAPRPARLHAGLPDRARLAEPEAAGG
CCCCCCCEEECCCCCHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHCCCCCCCCC
RPPFRGVRAEPGRRPRAGRRGRGAGPAGRPAYVRPPRAADPGRHAGGVRPQRRPPRLSGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AAGAAARQPLAGPDAVRRAARAGPRAAALRMAGRRPSAGRRRHPGPARGRLSGPPLPLSA
HHCHHHCCCCCCHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GRLAAAADRAVPARAGGFPVISTATIRDRYENYRQLMRWDKPIGTLLLLWPTLWALWIAT
CCHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HGAPRLSIVAIFCLGTFLMRSAGCVINDYADRDYDAHVARTSQRPFARGAVSKKEALLLA
CCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHCCCCCHHHHCCCHHHHHHHH
ALLAALSFLLVLPLNNLTKLLSVPAVLIAASYPFTKRFFPMPQAYLGVAFSFGIPMGFAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCCCCC
ETGEVPVLAWLLLLANLFWVVAYDTAYAIADKPDDLKIGIKTSAITMGDYDVAGVMLCHA
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEEEEEEEECCCHHHHHHHHHH
AFLALMCGIGVHLALAWPYYLGLAAAAALIMQQYREIKDRDRAKCFKAFLDNNRVGAAVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
AGVLLSYWLS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA