Click here to switch to the map view.

The map label for this gene is mtgA

Identifier: 34499041

GI number: 34499041

Start: 3894534

End: 3895220

Strand: Reverse

Name: mtgA

Synonym: CV_3586

Alternate gene names: 34499041

Gene position: 3895220-3894534 (Counterclockwise)

Preceding gene: 34499042

Following gene: 34499040

Centisome position: 81.99

GC content: 64.48

Gene sequence:

>687_bases
ATGTCGCGCATCCTGTTCAAGATCCTGGCGGCCCTGGTGGCCGCCTTTCTGCTGTATAACCTGTGGGTGCTCGGCCATAT
CATTTACTGGCGCGACCACAATCCCGGCGCCAGTTCCTTCATGAACGAGCAGCTGGCCAGGCTGCAGCAGGACGACCCCG
AGGCCGAGCTGCGCCACAAGTGGGTGCCGTACGACAAGATCTCGCCCAATCTGAAACGGGCGCTGATCGCGTCGGAGGAC
GCCCGTTTCGTCGACCACGAGGGCTTCGACTGGGACGGCATCGAGGCGGCGTTCGAGAAAAACCTGAAGAAGGGCAAGAT
CGTCGCCGGCGGCTCCACCATCAGCCAGCAGCTGGCCAAGAACCTGTTCCTGTCCAGCGGCAAGACGCCGTGGCGCAAGC
TGGAAGAGGCGCTGATCACGGTGATGCTGGAGACGGTGCTGGACAAGCGCCGCATCTACGAGATCTACCTGAACGTGATC
GAGTGGGGCAACGGCGTGTTCGGCGCCGAGGCCGCCTCGCGTTACTACTTCCGCACCGGCGCCTCGCGCCTGTCGTCGTC
CCAGGCCGCCAAGCTGGCCGCCATGGTGCCCAACCCGCGCTATTACGACGAACATCGCAACGCGCCGGGCCTGGCGCGCA
AGACCCGCATCATCCAGCGCCGGATGGCTTACGTCGAGCTGCCCTGA

Upstream 100 bases:

>100_bases
TGCTGGTGGAGCAGGCGGCGGAATCGTTCTCCATCTGGCGCGGCGCGCAGCCGGAAACGCGCAAGGTGACCAATATGCTG
AGGGAAGTGCTGGCCTGAGC

Downstream 100 bases:

>100_bases
TCCCGTTCCTTCCCGCCTGCCGCCACGCCCGTGGCGGCGGCTGGAAGCCGCTTGTGACGGTATGTTACAATCGCGACTTT
CTTTTCGCGCGCCGCGGGCA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHKWVPYDKISPNLKRALIASED
ARFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAKNLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVI
EWGNGVFGAEAASRYYFRTGASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP

Sequences:

>Translated_228_residues
MSRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHKWVPYDKISPNLKRALIASED
ARFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAKNLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVI
EWGNGVFGAEAASRYYFRTGASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP
>Mature_227_residues
SRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHKWVPYDKISPNLKRALIASEDA
RFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAKNLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVIE
WGNGVFGAEAASRYYFRTGASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=139, Percent_Identity=51.0791366906475, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI87082258, Length=169, Percent_Identity=34.9112426035503, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786343, Length=168, Percent_Identity=38.6904761904762, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788867, Length=138, Percent_Identity=34.0579710144928, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_CHRVO (Q7NS41)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903256.1
- ProteinModelPortal:   Q7NS41
- SMR:   Q7NS41
- GeneID:   2548869
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3586
- NMPDR:   fig|243365.1.peg.3586
- HOGENOM:   HBG685698
- OMA:   QHAVISA
- PhylomeDB:   Q7NS41
- ProtClustDB:   PRK00056
- BioCyc:   CVIO243365:CV_3586-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26071; Mature: 25940

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1296162c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHC
WVPYDKISPNLKRALIASEDARFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAK
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHHH
NLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVIEWGNGVFGAEAASRYYFRTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP
HHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SRILFKILAALVAAFLLYNLWVLGHIIYWRDHNPGASSFMNEQLARLQQDDPEAELRHK
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHC
WVPYDKISPNLKRALIASEDARFVDHEGFDWDGIEAAFEKNLKKGKIVAGGSTISQQLAK
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCHHHHHHHHH
NLFLSSGKTPWRKLEEALITVMLETVLDKRRIYEIYLNVIEWGNGVFGAEAASRYYFRTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ASRLSSSQAAKLAAMVPNPRYYDEHRNAPGLARKTRIIQRRMAYVELP
HHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782