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The map label for this gene is cheA [H]

Identifier: 34498905

GI number: 34498905

Start: 3746438

End: 3748339

Strand: Direct

Name: cheA [H]

Synonym: CV_3450

Alternate gene names: 34498905

Gene position: 3746438-3748339 (Clockwise)

Preceding gene: 34498904

Following gene: 34498906

Centisome position: 78.85

GC content: 65.83

Gene sequence:

>1902_bases
ATGAGCGAATTTGGCGGCATGGAAGAGTTGCTTCAGGACTTCCTGATGGAGTCCACCGACCTGCTGTCCGACGTGGACAA
CAAGCTGGTCGAACTGGAAAAACGCCCGGAAGACAAGGCCCTGCTCAACGACATCTTCCGCGGCTTCCACACCATCAAGG
GCGGCGCCGGCTTCCTCAACGTCATCCCCATGGTCAATCTGTGCCACCGCACCGAGAACCTGTTCGACAAGCTGCGCAAC
GGCGAGATGCATATCACGCCCGAGGTGATGGACGTGATTCTCGACGCCACCGGGATCGTCCGCGACATGTTCGGCACCCT
GGGCCAGGGCCTGATGCCGGGCGACGCCGACGCCCGCGTGCTGGCCGCGCTGGATGCCGCGCTGGCCGGAGAGCCGGTCG
CGGCTGAAGTCCACCACGCGGAACCGGCGGCGGCGCCTGCCGCCGTTGCCGAAGCGGCTCCGGCCCCCGCCGGCAACGGA
CCGGACTGGAACCAACTGTACCAGGCTGTCACGCCGAATGCGGCAGCCGCTCCCGCGAGCGCGGCGCCTGCTCCCGCCGC
CCAGGCTCCGCGCGCGGAACCCGCGCCGGCGCCGGCCCAGCCTCCCGCGCCGGCGGCCGCGCCCAAGCCCCCCGCCCCCA
AGCCCGCCCCGTCCAAACCGTCCGGCGGCGGCGGCCCGGTGGCAAGCGGACCGCAGGAAAACACCATCCGCATCGATACC
GTGCGCCTGGACATGGTGCTGAATCTGTCCGGCGAGATCGGGCTGACCAAGAACCGCCTGACCACGCTGCGCACCGAGAT
CCTGCAGGGCAACCGCGACACCAATACCCTACGCTCGCTCGACGAAGCCATCAGCCAGCTCGACCTGCTGGTAGGCGATC
TGCAAAACGCGGTGATGAAGACCCGCATGCAGCCGATCGGCCGCCTGTTCCAGAAGTACCCGCGCCTGGCGCGCGACCTG
GCCCGGCAACTGGGCAAGGAAGTGGAGCTGGTGCTGTCCGGCGAGGAAACCGAACTCGACAAGACCATGATCGAGGATCT
GAACGATCCGCTGGTCCACTTGGTCCGCAACGCCGTGGACCACGGCATCGAGTCGCCGGAAGACCGCATCGCCTCCGGCA
AGAAACCGCAGGCGCTGGTCCAGCTGACCGCCGAACAGGTGGGCGACCACATCCTGATCGAGATCACCGACGACGGCAAG
GGCATGAACCCCGACGCGCTGCGGCGCAAGGCCATCGAAAAGGGGCTGATCGACCAGGAAACCGCCAACTCACTGGATGA
GAAGCAGTGTCTGCAGCTGATCTTCCTGCCCGGCTTCTCCACCAAGGATCAGATTTCCAGCGTATCCGGCCGCGGCGTCG
GCATGGACGTGGTGCGCACCAACATCCAGAAGCTGAACGGCCGCATCGACATCAGCTCGGTGCCGGGCGAAGGCACCCGC
ATCAGCATTTCGCTGCCGCTGACCCTGGCCATCCTCCCGGTGCTGGTGGTTCGTGCCTGCAACCAGCCGTTCGCCGTGCC
GCTGGCCATGGTCCGCGAGATCATCACCATCGACGGCAGCGCGATCCAGGAAGTGTCGGGCAAGCCCACCATCGTGGTGC
GCGACGAAATCCTGCCGCTGAAAACGCTGGCCGGGCTGCTGGGCTGGGAACCGACCCAGAAGCCCTACTTCGGTGTGCTG
ATGCAGTCCGCGGAAAAATCCTTCATCCTGGCAATCGATTCCTTCGTCGGCCGAGACGATGTGGTGATCAAGCCGTTGCA
GAATATCCGCCCGAAGGGCGTGGCCGGCGCCACCCTGTCCGGCGACGGCTCCGTCGTGCTGGTTCTCGACATGGAAGACC
TGCTGGCATCCAGCGAAAGCAACAATACCCAGACTCGGACGACGGATATGATTGCCACCTAA

Upstream 100 bases:

>100_bases
CCGACGTGGTCACCAGCCAGCAGCAGGTGGACGACCTGCTGGAAAGCCTCGGCTTCTAAAGCAACGCAAGCAAGACAACG
CAGAACGGGTGGGGTGAAAT

Downstream 100 bases:

>100_bases
ACACAGGGTGCAATGATGACCACCAACACCGCCTTCATCGGAAGGCAGCCGGTATTGAACCGCAACCAGCAGCTCATAGG
TTATGAGCTGCTTTTTCGTC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSEFGGMEELLQDFLMESTDLLSDVDNKLVELEKRPEDKALLNDIFRGFHTIKGGAGFLNVIPMVNLCHRTENLFDKLRN
GEMHITPEVMDVILDATGIVRDMFGTLGQGLMPGDADARVLAALDAALAGEPVAAEVHHAEPAAAPAAVAEAAPAPAGNG
PDWNQLYQAVTPNAAAAPASAAPAPAAQAPRAEPAPAPAQPPAPAAAPKPPAPKPAPSKPSGGGGPVASGPQENTIRIDT
VRLDMVLNLSGEIGLTKNRLTTLRTEILQGNRDTNTLRSLDEAISQLDLLVGDLQNAVMKTRMQPIGRLFQKYPRLARDL
ARQLGKEVELVLSGEETELDKTMIEDLNDPLVHLVRNAVDHGIESPEDRIASGKKPQALVQLTAEQVGDHILIEITDDGK
GMNPDALRRKAIEKGLIDQETANSLDEKQCLQLIFLPGFSTKDQISSVSGRGVGMDVVRTNIQKLNGRIDISSVPGEGTR
ISISLPLTLAILPVLVVRACNQPFAVPLAMVREIITIDGSAIQEVSGKPTIVVRDEILPLKTLAGLLGWEPTQKPYFGVL
MQSAEKSFILAIDSFVGRDDVVIKPLQNIRPKGVAGATLSGDGSVVLVLDMEDLLASSESNNTQTRTTDMIAT

Sequences:

>Translated_633_residues
MSEFGGMEELLQDFLMESTDLLSDVDNKLVELEKRPEDKALLNDIFRGFHTIKGGAGFLNVIPMVNLCHRTENLFDKLRN
GEMHITPEVMDVILDATGIVRDMFGTLGQGLMPGDADARVLAALDAALAGEPVAAEVHHAEPAAAPAAVAEAAPAPAGNG
PDWNQLYQAVTPNAAAAPASAAPAPAAQAPRAEPAPAPAQPPAPAAAPKPPAPKPAPSKPSGGGGPVASGPQENTIRIDT
VRLDMVLNLSGEIGLTKNRLTTLRTEILQGNRDTNTLRSLDEAISQLDLLVGDLQNAVMKTRMQPIGRLFQKYPRLARDL
ARQLGKEVELVLSGEETELDKTMIEDLNDPLVHLVRNAVDHGIESPEDRIASGKKPQALVQLTAEQVGDHILIEITDDGK
GMNPDALRRKAIEKGLIDQETANSLDEKQCLQLIFLPGFSTKDQISSVSGRGVGMDVVRTNIQKLNGRIDISSVPGEGTR
ISISLPLTLAILPVLVVRACNQPFAVPLAMVREIITIDGSAIQEVSGKPTIVVRDEILPLKTLAGLLGWEPTQKPYFGVL
MQSAEKSFILAIDSFVGRDDVVIKPLQNIRPKGVAGATLSGDGSVVLVLDMEDLLASSESNNTQTRTTDMIAT
>Mature_632_residues
SEFGGMEELLQDFLMESTDLLSDVDNKLVELEKRPEDKALLNDIFRGFHTIKGGAGFLNVIPMVNLCHRTENLFDKLRNG
EMHITPEVMDVILDATGIVRDMFGTLGQGLMPGDADARVLAALDAALAGEPVAAEVHHAEPAAAPAAVAEAAPAPAGNGP
DWNQLYQAVTPNAAAAPASAAPAPAAQAPRAEPAPAPAQPPAPAAAPKPPAPKPAPSKPSGGGGPVASGPQENTIRIDTV
RLDMVLNLSGEIGLTKNRLTTLRTEILQGNRDTNTLRSLDEAISQLDLLVGDLQNAVMKTRMQPIGRLFQKYPRLARDLA
RQLGKEVELVLSGEETELDKTMIEDLNDPLVHLVRNAVDHGIESPEDRIASGKKPQALVQLTAEQVGDHILIEITDDGKG
MNPDALRRKAIEKGLIDQETANSLDEKQCLQLIFLPGFSTKDQISSVSGRGVGMDVVRTNIQKLNGRIDISSVPGEGTRI
SISLPLTLAILPVLVVRACNQPFAVPLAMVREIITIDGSAIQEVSGKPTIVVRDEILPLKTLAGLLGWEPTQKPYFGVLM
QSAEKSFILAIDSFVGRDDVVIKPLQNIRPKGVAGATLSGDGSVVLVLDMEDLLASSESNNTQTRTTDMIAT

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=653, Percent_Identity=33.2312404287902, Blast_Score=307, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67474; Mature: 67343

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFGGMEELLQDFLMESTDLLSDVDNKLVELEKRPEDKALLNDIFRGFHTIKGGAGFLN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
VIPMVNLCHRTENLFDKLRNGEMHITPEVMDVILDATGIVRDMFGTLGQGLMPGDADARV
HHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LAALDAALAGEPVAAEVHHAEPAAAPAAVAEAAPAPAGNGPDWNQLYQAVTPNAAAAPAS
HHHHHHHHCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
AAPAPAAQAPRAEPAPAPAQPPAPAAAPKPPAPKPAPSKPSGGGGPVASGPQENTIRIDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VRLDMVLNLSGEIGLTKNRLTTLRTEILQGNRDTNTLRSLDEAISQLDLLVGDLQNAVMK
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRMQPIGRLFQKYPRLARDLARQLGKEVELVLSGEETELDKTMIEDLNDPLVHLVRNAVD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
HGIESPEDRIASGKKPQALVQLTAEQVGDHILIEITDDGKGMNPDALRRKAIEKGLIDQE
HCCCCCHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCH
TANSLDEKQCLQLIFLPGFSTKDQISSVSGRGVGMDVVRTNIQKLNGRIDISSVPGEGTR
HHHCCCHHHHHHEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCE
ISISLPLTLAILPVLVVRACNQPFAVPLAMVREIITIDGSAIQEVSGKPTIVVRDEILPL
EEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCH
KTLAGLLGWEPTQKPYFGVLMQSAEKSFILAIDSFVGRDDVVIKPLQNIRPKGVAGATLS
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHCCCCCEEECCHHCCCCCCCCCCEEC
GDGSVVLVLDMEDLLASSESNNTQTRTTDMIAT
CCCCEEEEEEHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SEFGGMEELLQDFLMESTDLLSDVDNKLVELEKRPEDKALLNDIFRGFHTIKGGAGFLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
VIPMVNLCHRTENLFDKLRNGEMHITPEVMDVILDATGIVRDMFGTLGQGLMPGDADARV
HHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LAALDAALAGEPVAAEVHHAEPAAAPAAVAEAAPAPAGNGPDWNQLYQAVTPNAAAAPAS
HHHHHHHHCCCCCEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
AAPAPAAQAPRAEPAPAPAQPPAPAAAPKPPAPKPAPSKPSGGGGPVASGPQENTIRIDT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VRLDMVLNLSGEIGLTKNRLTTLRTEILQGNRDTNTLRSLDEAISQLDLLVGDLQNAVMK
EEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRMQPIGRLFQKYPRLARDLARQLGKEVELVLSGEETELDKTMIEDLNDPLVHLVRNAVD
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHH
HGIESPEDRIASGKKPQALVQLTAEQVGDHILIEITDDGKGMNPDALRRKAIEKGLIDQE
HCCCCCHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCH
TANSLDEKQCLQLIFLPGFSTKDQISSVSGRGVGMDVVRTNIQKLNGRIDISSVPGEGTR
HHHCCCHHHHHHEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCE
ISISLPLTLAILPVLVVRACNQPFAVPLAMVREIITIDGSAIQEVSGKPTIVVRDEILPL
EEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCH
KTLAGLLGWEPTQKPYFGVLMQSAEKSFILAIDSFVGRDDVVIKPLQNIRPKGVAGATLS
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHCCCCCEEECCHHCCCCCCCCCCEEC
GDGSVVLVLDMEDLLASSESNNTQTRTTDMIAT
CCCCEEEEEEHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]