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The map label for this gene is cheA [H]

Identifier: 34498897

GI number: 34498897

Start: 3738385

End: 3740631

Strand: Reverse

Name: cheA [H]

Synonym: CV_3442

Alternate gene names: 34498897

Gene position: 3740631-3738385 (Counterclockwise)

Preceding gene: 34498898

Following gene: 34498896

Centisome position: 78.73

GC content: 65.55

Gene sequence:

>2247_bases
GTGGCAATCGACATGTCCCAATTTCACCAGGTCTTTTTCGACGAGACGGAAGAGCATCTGGCTGCGATGGAGTCGTTGCT
CCTGGCAATGGATGTCGCCCATCCCGAGCAGGAAGATCTCCACGCCGTGTTCCGCGCCGCCCATTCGATCAAAGGGGGCG
CCGCTACCTTCGGCTTCTCCGAAATGGCCGAGCTGACCCATGTGCTGGAAAACCTGCTGGACCGGGTGCGCAAGGGCGCG
ATGGGTCTGACGGTGGAGATGGTGGACGCGTTCCTGCAGGCGAAAGACGCGCTGCAGTCGATGCTGGGCGCGTACAAGAA
CGGAGAAGAGCCTGACGGTGGCCGGCAGGAAGAGATTCAACGGCAGCTTGAGGCGATAGAAAGCCAAGCGCCCGAGGCCG
AAACGGCGGCATCCCCGCAGGATGCGGCGCCGGCGGCTGAGCAGCTGTGGACGCTGTTTCTGGAACTGACGCCCGCTGAT
GAGCATGACATCCGCCCCTTGCTGGAAAACCTGGCGGCGCAGGGCGATCTGACCATTGTCCAGGAAGGCCGGACGGCGGA
TGAGCTGCCCTGGGTCGCGGTGTTCACCTCTTCGCTGGAAGCGGACGAGGTCGCCGAATCGCTGGCGTTCATGCTGCCGC
CGGAGCGGTTCCGCGTCAGCATGGACCGGGGGGGGGAAGGCGGCGACGAATACGGCTTCTTCCTGTCGGACGATCATGTG
TCTCCCGGCAGGAAGGGAGAAGGCGGAGTCTCCTACGTGGACGAGGATGGCGGCTTCGGTCTGTTCGAGCCGCTGCCAGG
TCGGGAGACGCCGGGCGCGGATGCCGGCTCCGAGAGGCTGGCGCGGATGGAGCAGGATGGCAGTTTCGGCTTGTTCGAGC
CTTTGCAGGCGCCGGCGAAGAATGAAGGCAGGGACGTGGAGGGCGAAGGGTTCGGCCTGTTCGGCGGCGCGCCGGGAGTC
GGCGCCCCCGCGCCAGGCGCGGCGGCCCAGGCCGAGAAACCCGTGGCGCCGGCCCGGACGTCGCCCGATAAGGGCGCGGC
CGCCGGCGAAAACTCGATCCGGGTCAATATCGAAAAGGTCGACATGCTGCTGAACCTGGTCGGCGAACTGGTGATCACCC
AGTCGATGCTGATGCAGTCAGGCAGCGCGCTGGACCCGGTCGAGCACGAGCGCCTGCTCAACGGCATCAGCGCCCTGCAG
CGCAATTCGAGAGAGTTGCAGGAGGCGGTGATGTCCATCCGCATGACGCCGATCGCCTTCGTGTTCAACCGCTTTCCCCG
CGTGGTTCGCGACCTCGCCTCCAGGCTTGGGAAGCAGGTCGACCTGAAAATGGTGGGCGAGAACACCGAGCTGGACAAGG
GCTTCATCGAAAAACTGTCGGACCCCTTGACCCATCTGGTGCGCAACAGCCTGGACCACGGCATCGAGTCGCCGGACGAA
CGGGTGGCCAAGGGCAAGTCTCCTGCCGGCCGGCTGACGCTGCGGGCCTTTCATCAGGGCGGCAGCATCGTGATCGAGGT
CAGCGACGACGGCGCGGGGCTCAGCCGCGAACGCATCCTGGCCAAGGCGCGGGAGCGCGGCATGCCGGTCAGCGACAACA
TGACGGATGCTGAGGTGTGGGGACTGATCTTCGAGGCCGGCTTCTCGACGGCGGCGGAAGTGACCGACGTGTCCGGCCGC
GGCGTCGGCATGGATGTGGTCAAGCGCAACATCCAAAACATGGGCGGCAGGATCGAGATCGATTCCATGGCCGATGTCGG
CACCACGATGAGCATACGCCTGCCGCTGACGCTGGCCATCATGGACGGCATGTCGGTCAGGGTGGGCGACGAGATCTACG
TGTTGCCGCTGGGCTTCATCCTGGAGTCGCTGCAGCCTGAGACCAAGGCGGTCAAGACCGTGGCCGGGCGGGGCGAGGTG
GTGCACATCCGGGGCGAATACCTGCCCATCGTTCCGCTGGGGCGCTACTTCAACGTCGGCAAGGCCAGGCAGCGGGCAGA
CGAGGGCATCCTGGTGATCGTGGAGGCCTCGGGCTCCCGCGTCGCCCTGCTGGTGGACGACCTGATCGGCCAGCAGCAGT
TCGTGGTGAAGAATCTGGAAACCAATTACCGCAAGGTGGACGGCCTGTCCGGTGCCACGATACTCGGCGACGGGCAGGTG
GCGCTGATACTCGACATTTCCACCATCGCCCGCAGCAACGGCGGCCCGCGCGGATCCGCCGCGCAAATGGCGGCCATCGC
GGAATGA

Upstream 100 bases:

>100_bases
CGCTTCGGGCTGGCTGGTCAAGCCGTTCGATCCGCAGAAGTTGCTGGACGTCGTCAAGCGCCTGGTCGGTTAACGCAGCC
ATCGCTACGGGGGGACGATT

Downstream 100 bases:

>100_bases
CAGCCGGAGAAGCGATATGCAACTGGACAATCTGAGCGATGCCCAGGCGAGGGGCGCAGGGACGCGGGAGCTGCTGGTGT
TCACGCTGGGCAGCGAGGAA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 748; Mature: 747

Protein sequence:

>748_residues
MAIDMSQFHQVFFDETEEHLAAMESLLLAMDVAHPEQEDLHAVFRAAHSIKGGAATFGFSEMAELTHVLENLLDRVRKGA
MGLTVEMVDAFLQAKDALQSMLGAYKNGEEPDGGRQEEIQRQLEAIESQAPEAETAASPQDAAPAAEQLWTLFLELTPAD
EHDIRPLLENLAAQGDLTIVQEGRTADELPWVAVFTSSLEADEVAESLAFMLPPERFRVSMDRGGEGGDEYGFFLSDDHV
SPGRKGEGGVSYVDEDGGFGLFEPLPGRETPGADAGSERLARMEQDGSFGLFEPLQAPAKNEGRDVEGEGFGLFGGAPGV
GAPAPGAAAQAEKPVAPARTSPDKGAAAGENSIRVNIEKVDMLLNLVGELVITQSMLMQSGSALDPVEHERLLNGISALQ
RNSRELQEAVMSIRMTPIAFVFNRFPRVVRDLASRLGKQVDLKMVGENTELDKGFIEKLSDPLTHLVRNSLDHGIESPDE
RVAKGKSPAGRLTLRAFHQGGSIVIEVSDDGAGLSRERILAKARERGMPVSDNMTDAEVWGLIFEAGFSTAAEVTDVSGR
GVGMDVVKRNIQNMGGRIEIDSMADVGTTMSIRLPLTLAIMDGMSVRVGDEIYVLPLGFILESLQPETKAVKTVAGRGEV
VHIRGEYLPIVPLGRYFNVGKARQRADEGILVIVEASGSRVALLVDDLIGQQQFVVKNLETNYRKVDGLSGATILGDGQV
ALILDISTIARSNGGPRGSAAQMAAIAE

Sequences:

>Translated_748_residues
MAIDMSQFHQVFFDETEEHLAAMESLLLAMDVAHPEQEDLHAVFRAAHSIKGGAATFGFSEMAELTHVLENLLDRVRKGA
MGLTVEMVDAFLQAKDALQSMLGAYKNGEEPDGGRQEEIQRQLEAIESQAPEAETAASPQDAAPAAEQLWTLFLELTPAD
EHDIRPLLENLAAQGDLTIVQEGRTADELPWVAVFTSSLEADEVAESLAFMLPPERFRVSMDRGGEGGDEYGFFLSDDHV
SPGRKGEGGVSYVDEDGGFGLFEPLPGRETPGADAGSERLARMEQDGSFGLFEPLQAPAKNEGRDVEGEGFGLFGGAPGV
GAPAPGAAAQAEKPVAPARTSPDKGAAAGENSIRVNIEKVDMLLNLVGELVITQSMLMQSGSALDPVEHERLLNGISALQ
RNSRELQEAVMSIRMTPIAFVFNRFPRVVRDLASRLGKQVDLKMVGENTELDKGFIEKLSDPLTHLVRNSLDHGIESPDE
RVAKGKSPAGRLTLRAFHQGGSIVIEVSDDGAGLSRERILAKARERGMPVSDNMTDAEVWGLIFEAGFSTAAEVTDVSGR
GVGMDVVKRNIQNMGGRIEIDSMADVGTTMSIRLPLTLAIMDGMSVRVGDEIYVLPLGFILESLQPETKAVKTVAGRGEV
VHIRGEYLPIVPLGRYFNVGKARQRADEGILVIVEASGSRVALLVDDLIGQQQFVVKNLETNYRKVDGLSGATILGDGQV
ALILDISTIARSNGGPRGSAAQMAAIAE
>Mature_747_residues
AIDMSQFHQVFFDETEEHLAAMESLLLAMDVAHPEQEDLHAVFRAAHSIKGGAATFGFSEMAELTHVLENLLDRVRKGAM
GLTVEMVDAFLQAKDALQSMLGAYKNGEEPDGGRQEEIQRQLEAIESQAPEAETAASPQDAAPAAEQLWTLFLELTPADE
HDIRPLLENLAAQGDLTIVQEGRTADELPWVAVFTSSLEADEVAESLAFMLPPERFRVSMDRGGEGGDEYGFFLSDDHVS
PGRKGEGGVSYVDEDGGFGLFEPLPGRETPGADAGSERLARMEQDGSFGLFEPLQAPAKNEGRDVEGEGFGLFGGAPGVG
APAPGAAAQAEKPVAPARTSPDKGAAAGENSIRVNIEKVDMLLNLVGELVITQSMLMQSGSALDPVEHERLLNGISALQR
NSRELQEAVMSIRMTPIAFVFNRFPRVVRDLASRLGKQVDLKMVGENTELDKGFIEKLSDPLTHLVRNSLDHGIESPDER
VAKGKSPAGRLTLRAFHQGGSIVIEVSDDGAGLSRERILAKARERGMPVSDNMTDAEVWGLIFEAGFSTAAEVTDVSGRG
VGMDVVKRNIQNMGGRIEIDSMADVGTTMSIRLPLTLAIMDGMSVRVGDEIYVLPLGFILESLQPETKAVKTVAGRGEVV
HIRGEYLPIVPLGRYFNVGKARQRADEGILVIVEASGSRVALLVDDLIGQQQFVVKNLETNYRKVDGLSGATILGDGQVA
LILDISTIARSNGGPRGSAAQMAAIAE

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=422, Percent_Identity=60.1895734597156, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80285; Mature: 80154

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDMSQFHQVFFDETEEHLAAMESLLLAMDVAHPEQEDLHAVFRAAHSIKGGAATFGFS
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
EMAELTHVLENLLDRVRKGAMGLTVEMVDAFLQAKDALQSMLGAYKNGEEPDGGRQEEIQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RQLEAIESQAPEAETAASPQDAAPAAEQLWTLFLELTPADEHDIRPLLENLAAQGDLTIV
HHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEE
QEGRTADELPWVAVFTSSLEADEVAESLAFMLPPERFRVSMDRGGEGGDEYGFFLSDDHV
ECCCCCCCCCEEEEHHCCCCHHHHHHHHHHHCCHHHHEEEECCCCCCCCCCCEEEECCCC
SPGRKGEGGVSYVDEDGGFGLFEPLPGRETPGADAGSERLARMEQDGSFGLFEPLQAPAK
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCC
NEGRDVEGEGFGLFGGAPGVGAPAPGAAAQAEKPVAPARTSPDKGAAAGENSIRVNIEKV
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHH
DMLLNLVGELVITQSMLMQSGSALDPVEHERLLNGISALQRNSRELQEAVMSIRMTPIAF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNRFPRVVRDLASRLGKQVDLKMVGENTELDKGFIEKLSDPLTHLVRNSLDHGIESPDE
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RVAKGKSPAGRLTLRAFHQGGSIVIEVSDDGAGLSRERILAKARERGMPVSDNMTDAEVW
HHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
GLIFEAGFSTAAEVTDVSGRGVGMDVVKRNIQNMGGRIEIDSMADVGTTMSIRLPLTLAI
HHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCEEEEE
MDGMSVRVGDEIYVLPLGFILESLQPETKAVKTVAGRGEVVHIRGEYLPIVPLGRYFNVG
ECCCEEEECCEEEEEEHHHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEEEECCCHHCCC
KARQRADEGILVIVEASGSRVALLVDDLIGQQQFVVKNLETNYRKVDGLSGATILGDGQV
HHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHHHHHHCCHHHHCCCCCCEEECCCCE
ALILDISTIARSNGGPRGSAAQMAAIAE
EEEEEHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
AIDMSQFHQVFFDETEEHLAAMESLLLAMDVAHPEQEDLHAVFRAAHSIKGGAATFGFS
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
EMAELTHVLENLLDRVRKGAMGLTVEMVDAFLQAKDALQSMLGAYKNGEEPDGGRQEEIQ
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
RQLEAIESQAPEAETAASPQDAAPAAEQLWTLFLELTPADEHDIRPLLENLAAQGDLTIV
HHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEE
QEGRTADELPWVAVFTSSLEADEVAESLAFMLPPERFRVSMDRGGEGGDEYGFFLSDDHV
ECCCCCCCCCEEEEHHCCCCHHHHHHHHHHHCCHHHHEEEECCCCCCCCCCCEEEECCCC
SPGRKGEGGVSYVDEDGGFGLFEPLPGRETPGADAGSERLARMEQDGSFGLFEPLQAPAK
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCC
NEGRDVEGEGFGLFGGAPGVGAPAPGAAAQAEKPVAPARTSPDKGAAAGENSIRVNIEKV
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHH
DMLLNLVGELVITQSMLMQSGSALDPVEHERLLNGISALQRNSRELQEAVMSIRMTPIAF
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFNRFPRVVRDLASRLGKQVDLKMVGENTELDKGFIEKLSDPLTHLVRNSLDHGIESPDE
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RVAKGKSPAGRLTLRAFHQGGSIVIEVSDDGAGLSRERILAKARERGMPVSDNMTDAEVW
HHHCCCCCCCCEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHH
GLIFEAGFSTAAEVTDVSGRGVGMDVVKRNIQNMGGRIEIDSMADVGTTMSIRLPLTLAI
HHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCEEEEE
MDGMSVRVGDEIYVLPLGFILESLQPETKAVKTVAGRGEVVHIRGEYLPIVPLGRYFNVG
ECCCEEEECCEEEEEEHHHHHHHCCCHHHHHHHHCCCCCEEEECCCEEEEEECCCHHCCC
KARQRADEGILVIVEASGSRVALLVDDLIGQQQFVVKNLETNYRKVDGLSGATILGDGQV
HHHHHCCCCEEEEEECCCCEEEEEEHHHHCCHHHHHHHHHCCHHHHCCCCCCEEECCCCE
ALILDISTIARSNGGPRGSAAQMAAIAE
EEEEEHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]