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The map label for this gene is gltP [C]

Identifier: 34498864

GI number: 34498864

Start: 3702224

End: 3703405

Strand: Reverse

Name: gltP [C]

Synonym: CV_3409

Alternate gene names: 34498864

Gene position: 3703405-3702224 (Counterclockwise)

Preceding gene: 34498865

Following gene: 34498862

Centisome position: 77.95

GC content: 69.04

Gene sequence:

>1182_bases
GTGAAATTGATTCTCAAACTGCTGGCCGGCATGGCCGTCGGCCTGCTGCTGGGCTTGTACGCGCCCGGACCGCTGCTGAC
GCTGCTGCTGACCTTCAAGGGATTGTTCAGCCAGTTCATCGGCTTCATGATCCCGCTGATCATCGTGTTCTACATCATGA
GCGGCATCGCCGCGCTGGAGACCGGTTCCGGCCGCATGCTGGGCTGGACCGTCGGCTTGGCCTACGCGTCGACCATCCTG
TCCGGCGTGCTGGCCTTCACCGCCGCGTCCGCGCTGCTGCCGCAATGGCTGGGCGCCGCCGCCGCCGCGCCGGTCGCCGC
CAACAAGCTGGCACCCTTGTTCAAGCTGGAGATCAAGCCGCTGTTCGACGTGATGACGGCGCTGATGCTGGCCTTCGTGT
TCGGCCTGGGCATCGCCGCCACCGGCGCGGCGCGCTTGCGCGAGATCGCCGAGCAGGGCAAGGACATCGTCGAGAAGGTG
CTGGCGCGCGTGCTGGTGCCGCTGCTGCCGGCCTATATCGCCTGCGAATTCGCCGACATGGCCGCCGCCGGCACCGCCTT
CGCCACGCTGAAGACTTTCGGCGTGGTGCTGCTGATGGCCATCGCCCTGCACTGGCTGTGGCTGGCCGTGCTGTACGGCG
CCAGCGGCGCGCTGTTGGGCCGCAACCCGCTGTCCTTGCTGCGCGCGATGCTGCCGGCCTATTTCACCGCGCTGGGGACC
ATGTCGTCCGCGGCCACCATCCCGGTGGCGCTGCGTTCGGCCGGCAATATGAAGGTGTCGCCGCCGGTGGTGAATTTCGT
GATGCCGCTGTGCGCCACCATCCACCTGTGCGGCTCCACCATCACCCTGGTCAGCTGCGCCACCGCGGTGATGCTGATGA
CCCATGGCCTGGATGTGCCGGGCTGGGACGTGATGCTGCCTTTCATCCTGCTGCTGGGCGTGACCATGGTGGCCGCGCCG
GGCGCGCCGGGCGGCGGCGTGATGTCGGCGCTGGGCATCCTCTCCAGCGTGCTGGGCTTCCCGGAAGCCAGCCTGGCGCT
GATGATCGCCCTCTACCTGGCGCAGGACAGCTTCGGCACCGCTTGCAACGTGGCAGGAGACGGCGTGGTCGCGCTGTGGG
TGGACCGCCTGGTGGGCCGCGCTCCGCAGCCGGCCGGCGAGGCGGCCGCGCAGCGCGGCTGA

Upstream 100 bases:

>100_bases
CCTCTCTTCTTCCGCATCGATCCGATCGCGCCGGAGCGGGCGGGTTTCGCCCCTCGCCGCGCCAGGCGCGGCGGGCTGGA
TAACCCGGAAGAGGTTGCCT

Downstream 100 bases:

>100_bases
CGGTGATTTGCTAAGCAGAACAAGTGATTTGGGAGAGCGGCCGGCGCTGGTTATAGTGTTTGCCTGACCGTTTGGTTTGC
CGCCGCCTTAGAGCGGCTAA

Product: proton/sodium-glutamate symport protein

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: SodiumDicarboxylate Symporter Family Protein; Serine/Threonine Sodium Symporter; Na+/H+-Dicarboxylate Symporter; Serine/Threonine Transporter; Na+/H+ Dicarboxylate Symporter; Proton/Sodium-Glutamate Symport Protein; Na(+)/H(+)-Dicarboxylate Symporter; Glutamate/Aspartate Transporter; Glutamate/ Aspartate Transporter; Na+/H+ Dicarboxylate Symporte; DAACS Family Transporter; Sodium-Glutamate/Aspartate Symporter; Na+H+-Dicarboxylate Symporter; Transmembrane Symporter; Dicarboxylate/Amino Acid Transporter; Sodium-Glutamate Symporter; NaH+Dicarboxylate Symporter

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLILKLLAGMAVGLLLGLYAPGPLLTLLLTFKGLFSQFIGFMIPLIIVFYIMSGIAALETGSGRMLGWTVGLAYASTIL
SGVLAFTAASALLPQWLGAAAAAPVAANKLAPLFKLEIKPLFDVMTALMLAFVFGLGIAATGAARLREIAEQGKDIVEKV
LARVLVPLLPAYIACEFADMAAAGTAFATLKTFGVVLLMAIALHWLWLAVLYGASGALLGRNPLSLLRAMLPAYFTALGT
MSSAATIPVALRSAGNMKVSPPVVNFVMPLCATIHLCGSTITLVSCATAVMLMTHGLDVPGWDVMLPFILLLGVTMVAAP
GAPGGGVMSALGILSSVLGFPEASLALMIALYLAQDSFGTACNVAGDGVVALWVDRLVGRAPQPAGEAAAQRG

Sequences:

>Translated_393_residues
MKLILKLLAGMAVGLLLGLYAPGPLLTLLLTFKGLFSQFIGFMIPLIIVFYIMSGIAALETGSGRMLGWTVGLAYASTIL
SGVLAFTAASALLPQWLGAAAAAPVAANKLAPLFKLEIKPLFDVMTALMLAFVFGLGIAATGAARLREIAEQGKDIVEKV
LARVLVPLLPAYIACEFADMAAAGTAFATLKTFGVVLLMAIALHWLWLAVLYGASGALLGRNPLSLLRAMLPAYFTALGT
MSSAATIPVALRSAGNMKVSPPVVNFVMPLCATIHLCGSTITLVSCATAVMLMTHGLDVPGWDVMLPFILLLGVTMVAAP
GAPGGGVMSALGILSSVLGFPEASLALMIALYLAQDSFGTACNVAGDGVVALWVDRLVGRAPQPAGEAAAQRG
>Mature_393_residues
MKLILKLLAGMAVGLLLGLYAPGPLLTLLLTFKGLFSQFIGFMIPLIIVFYIMSGIAALETGSGRMLGWTVGLAYASTIL
SGVLAFTAASALLPQWLGAAAAAPVAANKLAPLFKLEIKPLFDVMTALMLAFVFGLGIAATGAARLREIAEQGKDIVEKV
LARVLVPLLPAYIACEFADMAAAGTAFATLKTFGVVLLMAIALHWLWLAVLYGASGALLGRNPLSLLRAMLPAYFTALGT
MSSAATIPVALRSAGNMKVSPPVVNFVMPLCATIHLCGSTITLVSCATAVMLMTHGLDVPGWDVMLPFILLLGVTMVAAP
GAPGGGVMSALGILSSVLGFPEASLALMIALYLAQDSFGTACNVAGDGVVALWVDRLVGRAPQPAGEAAAQRG

Specific function: This Carrier Protein Is Part Of The Na(+)-Independent, Binding-Protein-Independent Glutamate-Aspartate Transport System. [C]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468566, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI223468564, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI5032093, Length=218, Percent_Identity=27.0642201834862, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4827012, Length=166, Percent_Identity=30.7228915662651, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI194239697, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=220, Percent_Identity=27.7272727272727, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40501; Mature: 40501

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure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CCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA