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The map label for this gene is minC

Identifier: 34498830

GI number: 34498830

Start: 3670679

End: 3671401

Strand: Direct

Name: minC

Synonym: CV_3375

Alternate gene names: 34498830

Gene position: 3670679-3671401 (Clockwise)

Preceding gene: 34498828

Following gene: 34498831

Centisome position: 77.26

GC content: 69.43

Gene sequence:

>723_bases
ATGAGCCCCGTGGCCAACGCCTTTGACATTAAATCCGCCAGCCTCGATCTGCTGGCGCTCTTGCTGCGCACCGACAACCT
GGACGAACTGAGCCAGGCGCTGGATGCGCGTTTCGGCGACACCAGCGACGCCCCGGCCGAAGCCTTCGTGCTCGACGTGG
AAGCGCTGCCCAATCCGACCGAGCTGGACCTCGGCCGCCTGCTGCCGCTGCTCAGCCGCCGCGGCATCCGCGCGGTCGCG
CTGCGCCACCCGGACAACGCGCTGGCCGCCGTCGCCAGCCGTTATGGCCTCGCCTTCGCCAACAGCGCCGCCCAGCCGCG
CTCGGCGCAGGCCGCCGCGGAACCGGCGCCCAAAGCCGCCGTCGAATCGGCAGCGGCCCCTGCTTCCGCGCCGACCATGA
TCATCGACCGGCCGGTGCGCGCCGGCCAGCAGATCTACGCCAAGGGCGGAGACCTGGTGGTGCTGGCGATGGTCAGCGCT
GGCGCCGAAGTCATCGCCGACGGCAACATACACGTTTATGCACCTTTGCGCGGTCGCGCCCTGGCCGGCGCGCGCGGCAA
CCACGCCGCCCGCATCTTCGCCCGCAGCATGGAGGCCGAGCTGGTATCCATCGCCGGCGTGTACCGCACGATCGAGCAAG
CCTTGCCGGACAGCATTCTGGGCAAGCCCACCCAAATCTATCTTGAGAACGAGCGGCTGGTGATGACCGCGCTCGGCGAG
TAA

Upstream 100 bases:

>100_bases
GGCATGGCCGGCAAGCGGGCCATTGCCATTGAAAGGCCGCGCCCAAGCCAGTACACTCGCCCCATAGAAGAAATCTATCT
ACCGAATAAAAGCCAGCCCA

Downstream 100 bases:

>100_bases
CACATCCAAAGGAAAGCCCCGTGGCAAAAATCATCGTTGTGACATCCGGCAAGGGTGGCGTAGGCAAAACCACCACCAGC
GCGAGCTTCGCCTCCGGCCT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPTELDLGRLLPLLSRRGIRAVA
LRHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAAVESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSA
GAEVIADGNIHVYAPLRGRALAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE

Sequences:

>Translated_240_residues
MSPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPTELDLGRLLPLLSRRGIRAVA
LRHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAAVESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSA
GAEVIADGNIHVYAPLRGRALAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE
>Mature_239_residues
SPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPTELDLGRLLPLLSRRGIRAVAL
RHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAAVESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSAG
AEVIADGNIHVYAPLRGRALAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=238, Percent_Identity=36.5546218487395, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_CHRVO (Q7NSP5)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903045.1
- ProteinModelPortal:   Q7NSP5
- GeneID:   2549841
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3375
- NMPDR:   fig|243365.1.peg.3375
- HOGENOM:   HBG399077
- OMA:   QVEVQKT
- ProtClustDB:   PRK04516
- BioCyc:   CVIO243365:CV_3375-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 25110; Mature: 24979

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPT
CCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCC
ELDLGRLLPLLSRRGIRAVALRHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAA
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHH
VESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSAGAEVIADGNIHVYAPLRGRA
HHHHCCCCCCCEEEEECCHHCCHHEEECCCCEEEEEEECCCCEEEECCCEEEEECCCCCE
LAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCEEEEEECCC
>Mature Secondary Structure 
SPVANAFDIKSASLDLLALLLRTDNLDELSQALDARFGDTSDAPAEAFVLDVEALPNPT
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCC
ELDLGRLLPLLSRRGIRAVALRHPDNALAAVASRYGLAFANSAAQPRSAQAAAEPAPKAA
CCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHH
VESAAAPASAPTMIIDRPVRAGQQIYAKGGDLVVLAMVSAGAEVIADGNIHVYAPLRGRA
HHHHCCCCCCCEEEEECCHHCCHHEEECCCCEEEEEEECCCCEEEECCCEEEEECCCCCE
LAGARGNHAARIFARSMEAELVSIAGVYRTIEQALPDSILGKPTQIYLENERLVMTALGE
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782