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The map label for this gene is pgm

Identifier: 34498807

GI number: 34498807

Start: 3646476

End: 3647999

Strand: Direct

Name: pgm

Synonym: CV_3352

Alternate gene names: 34498807

Gene position: 3646476-3647999 (Clockwise)

Preceding gene: 34498805

Following gene: 34498808

Centisome position: 76.75

GC content: 65.09

Gene sequence:

>1524_bases
ATGAAATCCATCAAGCCTGTGTTGTTATTGATCCTCGACGGTTTCGGCCATCGCACGGAAGGCGACGACAACGCCATCCT
GCACGCCAGAATGCCGGTATGGAGCCGCCTGCGCGAACAGTACGCGTACGGAACGATCAACGCCTCGGAAAACTTCGTCG
GCCTGCCCTCCGGGCAGTTCGGAAATTCCGAGGTCGGCCACCTGAACATCGGCGCGGGCCGCATCGTCCAGCAGGACATC
AGCCGCATCGACTGCGACATCGAGGATGGCCGCTTCTCCAGCAATGACACACTGCAGCAAGCCATGAGCAAAGCTCAAGG
CTCGGCCCTGCACATCCTGGGCCTGCTGTCCGATGGCGGCGTTCACAGCCACGAGAACCACATTCATGCGCTGATCCGCG
CCGCCCAGGCCGCCGGCGTGCCCAAAATCTACGTCCACGCCTTCCTCGACGGCCGCGACACGCCGCCGCGCAGCGCCGAA
ACCTATCTGAAGCGCCTGGACGCGGCGCTGGCCGAATGCCCGAATGCCCGCCTGGTTTCCGTGACCGGCCGCTACTGGGC
GATGGACCGCGACAAGCGCTGGGAGCGCGTCGAGCCCGCCTACCGCCTGCTGGTGGACGGCGAAGGCCTGTTCCACGCCG
AAACCGGCCTGGACGCGCTGAAAGCCGCTTACGAGCGCGACGAGAACGACGAGTTCGTCAAGGCTACCGGCATCGGCGCG
CCGGTGAAGATGCAGGACGGCGACGCGCTGATCTTCATGAATTTCCGCGCCGACCGCGCCCGCCAGCTGACCTCCGCGCT
CACCGACCCGGCCTTCGACGGCTTCAAGGCGCGCCAGCCCAAGTTCGGCTACTACGCCACCCTGACCTCCTACGGCGAAG
CCTACTCGGCGCTGCCGGTCGCCTACGCGCCGCAGAAGATCCACAACGGCATGGGCGAATACCTGTCTTCCAAGGGACTG
AAACAGCTGCGCATCGCCGAAACCGAGAAATACCCGCACGTCACCTATTTCTTCAACGGCGGCGAAGAGCAGGTCTACCC
GGGCGAGGACCGCATCCTGGTGCCGTCGCCCAAGGTGGCCACCTATGACCTGCAGCCGGAAATGAGCGCCGGCGAGGTCA
CCGACAAGATCGTCGCGGCGATCCAGTCCGGCCAATACCAGGCCATCTTCTGCAATTACGCCAACGGCGACATGGTCGGC
CACAGCGGCGTGTTCGACGCCGCGGTCAAGGCGGTGGAAGCGCTGGACGGCTGCATCGAACGCTGCGTGGACGCGATGCT
GGCCGCCGGCGGCGAGGTGCTGATCACCGCCGACCACGGCAACTGCGAGCAGATGTACGACGGCGAGCACCATCAGCCGC
ATACCCAGCACACCACCAACCAGGTGCCCTTCCTCTACATCGGCCGGCCGGCGAAAATCCGCGCCGGCGGCTCGCTGCGC
GACATCTCGCCGTCGCTGCTGGCGATGATGGGCCTGGAACAACCGGCGGAGATGACCGGTCAATCGCTGATCGACTTCCA
ATAA

Upstream 100 bases:

>100_bases
TCCTAATGTAGCCTGACATTTTTTTGATTTGACTGCGGTACAATAGTATCCACAAAACCAGATACTATCAAGGTTTTCTA
ATATTCTGAATGCGAATGCC

Downstream 100 bases:

>100_bases
TCGCCTCACGGAGCGGCGGCCATGCTCCGGCGTGGCCGCCGTTATTGCCTCAAGCGAAAGAACACCAAGGGAATGAAACC
TTACCTGCTGCTGGCCCTGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MKSIKPVLLLILDGFGHRTEGDDNAILHARMPVWSRLREQYAYGTINASENFVGLPSGQFGNSEVGHLNIGAGRIVQQDI
SRIDCDIEDGRFSSNDTLQQAMSKAQGSALHILGLLSDGGVHSHENHIHALIRAAQAAGVPKIYVHAFLDGRDTPPRSAE
TYLKRLDAALAECPNARLVSVTGRYWAMDRDKRWERVEPAYRLLVDGEGLFHAETGLDALKAAYERDENDEFVKATGIGA
PVKMQDGDALIFMNFRADRARQLTSALTDPAFDGFKARQPKFGYYATLTSYGEAYSALPVAYAPQKIHNGMGEYLSSKGL
KQLRIAETEKYPHVTYFFNGGEEQVYPGEDRILVPSPKVATYDLQPEMSAGEVTDKIVAAIQSGQYQAIFCNYANGDMVG
HSGVFDAAVKAVEALDGCIERCVDAMLAAGGEVLITADHGNCEQMYDGEHHQPHTQHTTNQVPFLYIGRPAKIRAGGSLR
DISPSLLAMMGLEQPAEMTGQSLIDFQ

Sequences:

>Translated_507_residues
MKSIKPVLLLILDGFGHRTEGDDNAILHARMPVWSRLREQYAYGTINASENFVGLPSGQFGNSEVGHLNIGAGRIVQQDI
SRIDCDIEDGRFSSNDTLQQAMSKAQGSALHILGLLSDGGVHSHENHIHALIRAAQAAGVPKIYVHAFLDGRDTPPRSAE
TYLKRLDAALAECPNARLVSVTGRYWAMDRDKRWERVEPAYRLLVDGEGLFHAETGLDALKAAYERDENDEFVKATGIGA
PVKMQDGDALIFMNFRADRARQLTSALTDPAFDGFKARQPKFGYYATLTSYGEAYSALPVAYAPQKIHNGMGEYLSSKGL
KQLRIAETEKYPHVTYFFNGGEEQVYPGEDRILVPSPKVATYDLQPEMSAGEVTDKIVAAIQSGQYQAIFCNYANGDMVG
HSGVFDAAVKAVEALDGCIERCVDAMLAAGGEVLITADHGNCEQMYDGEHHQPHTQHTTNQVPFLYIGRPAKIRAGGSLR
DISPSLLAMMGLEQPAEMTGQSLIDFQ
>Mature_507_residues
MKSIKPVLLLILDGFGHRTEGDDNAILHARMPVWSRLREQYAYGTINASENFVGLPSGQFGNSEVGHLNIGAGRIVQQDI
SRIDCDIEDGRFSSNDTLQQAMSKAQGSALHILGLLSDGGVHSHENHIHALIRAAQAAGVPKIYVHAFLDGRDTPPRSAE
TYLKRLDAALAECPNARLVSVTGRYWAMDRDKRWERVEPAYRLLVDGEGLFHAETGLDALKAAYERDENDEFVKATGIGA
PVKMQDGDALIFMNFRADRARQLTSALTDPAFDGFKARQPKFGYYATLTSYGEAYSALPVAYAPQKIHNGMGEYLSSKGL
KQLRIAETEKYPHVTYFFNGGEEQVYPGEDRILVPSPKVATYDLQPEMSAGEVTDKIVAAIQSGQYQAIFCNYANGDMVG
HSGVFDAAVKAVEALDGCIERCVDAMLAAGGEVLITADHGNCEQMYDGEHHQPHTQHTTNQVPFLYIGRPAKIRAGGSLR
DISPSLLAMMGLEQPAEMTGQSLIDFQ

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=509, Percent_Identity=55.5992141453831, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI32564249, Length=514, Percent_Identity=42.9961089494163, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17507741, Length=516, Percent_Identity=43.0232558139535, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_CHRVO (Q7NSR8)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_903022.1
- ProteinModelPortal:   Q7NSR8
- SMR:   Q7NSR8
- GeneID:   2547148
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3352
- NMPDR:   fig|243365.1.peg.3352
- HOGENOM:   HBG613255
- OMA:   DNKTDEF
- PhylomeDB:   Q7NSR8
- ProtClustDB:   PRK05434
- BioCyc:   CVIO243365:CV_3352-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55525; Mature: 55525

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIKPVLLLILDGFGHRTEGDDNAILHARMPVWSRLREQYAYGTINASENFVGLPSGQF
CCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCEEECCCCCEEECCCCCC
GNSEVGHLNIGAGRIVQQDISRIDCDIEDGRFSSNDTLQQAMSKAQGSALHILGLLSDGG
CCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCC
VHSHENHIHALIRAAQAAGVPKIYVHAFLDGRDTPPRSAETYLKRLDAALAECPNARLVS
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VTGRYWAMDRDKRWERVEPAYRLLVDGEGLFHAETGLDALKAAYERDENDEFVKATGIGA
EECCEEECCCCCCHHHCCCEEEEEECCCCEEEECCCHHHHHHHHHCCCCCCEEEEECCCC
PVKMQDGDALIFMNFRADRARQLTSALTDPAFDGFKARQPKFGYYATLTSYGEAYSALPV
CEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCHHHCCCC
AYAPQKIHNGMGEYLSSKGLKQLRIAETEKYPHVTYFFNGGEEQVYPGEDRILVPSPKVA
EECHHHHHHHHHHHHHHCCCHHEEHHHCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEE
TYDLQPEMSAGEVTDKIVAAIQSGQYQAIFCNYANGDMVGHSGVFDAAVKAVEALDGCIE
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RCVDAMLAAGGEVLITADHGNCEQMYDGEHHQPHTQHTTNQVPFLYIGRPAKIRAGGSLR
HHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCC
DISPSLLAMMGLEQPAEMTGQSLIDFQ
CCCHHHHHHHCCCCCHHHCCCHHCCCC
>Mature Secondary Structure
MKSIKPVLLLILDGFGHRTEGDDNAILHARMPVWSRLREQYAYGTINASENFVGLPSGQF
CCCCCEEEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCEEECCCCCEEECCCCCC
GNSEVGHLNIGAGRIVQQDISRIDCDIEDGRFSSNDTLQQAMSKAQGSALHILGLLSDGG
CCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCC
VHSHENHIHALIRAAQAAGVPKIYVHAFLDGRDTPPRSAETYLKRLDAALAECPNARLVS
CCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
VTGRYWAMDRDKRWERVEPAYRLLVDGEGLFHAETGLDALKAAYERDENDEFVKATGIGA
EECCEEECCCCCCHHHCCCEEEEEECCCCEEEECCCHHHHHHHHHCCCCCCEEEEECCCC
PVKMQDGDALIFMNFRADRARQLTSALTDPAFDGFKARQPKFGYYATLTSYGEAYSALPV
CEEECCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHCCHHHCCCC
AYAPQKIHNGMGEYLSSKGLKQLRIAETEKYPHVTYFFNGGEEQVYPGEDRILVPSPKVA
EECHHHHHHHHHHHHHHCCCHHEEHHHCCCCCEEEEEEECCCCCCCCCCCEEECCCCCEE
TYDLQPEMSAGEVTDKIVAAIQSGQYQAIFCNYANGDMVGHSGVFDAAVKAVEALDGCIE
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
RCVDAMLAAGGEVLITADHGNCEQMYDGEHHQPHTQHTTNQVPFLYIGRPAKIRAGGSLR
HHHHHHHHCCCCEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCC
DISPSLLAMMGLEQPAEMTGQSLIDFQ
CCCHHHHHHHCCCCCHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782