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The map label for this gene is tdcB [C]

Identifier: 34498705

GI number: 34498705

Start: 3533797

End: 3534762

Strand: Reverse

Name: tdcB [C]

Synonym: CV_3250

Alternate gene names: 34498705

Gene position: 3534762-3533797 (Counterclockwise)

Preceding gene: 34498708

Following gene: 34498704

Centisome position: 74.4

GC content: 69.15

Gene sequence:

>966_bases
ATGAATGACTTGTACCAGTACATACTCGATGCCCATCGGGCATTGCGGCCGCAGGTCGCCGTCACGCCTCTGAGCCACAG
CCCGGCATTGTCGGCGCTGACCGGCTGCGAAGTGTATTTGAAGTGCGAGCACCTGCAGCACACCGGCTCCTTCAAGTTCC
GCGGCGCCAGCAACAAGATCCGGCTGCTGGACGCCGCGTCGCGCCGGCTGGGCGTGGCCACGGTGTCCAGCGGCAACCAC
GGCCTGGGCGTGGCGCTGGCCGGCAAGCTGGCCGGCGTGCCGGTCACGGTGTACGCGTCGGCCGCGGCGTCCGAGGTGAA
GCTGGACGCGATCCGCGCCCACGGCGCGAAGGTGGTCGTCATCGACGCGCCAATGCTGGAAGTGGAGCTGGAGGCCGCGC
GGCTCGCCGAGCGGGCCGGGCTGCCCTTCGTCTCGCCGTACAACGACGTCGACGTCATCGCCGGCCAGGGCACGATAGGG
ATGGAGCTGGCCGAGCAGCATCCCGGCCTGGTGGCGGTGTTCGCGTCGGTGGGCGGCGGCGGCATGATTTCCGGCATCGG
CTCCGCGCTGGAGATGATGAGCCCGAGTACCGAGATCGTCGGCTGCTGGCCGCGCCATTCCCAGGCGCTGTACCAGAGCA
TGCTGGCCGGCGAGATCGTCGAATACGAGGAGCTGGACACCATTTCCGACGGCACCGCCGGCGGCGTGGAGCCCGGCGCC
ATCACCCTGCCCATCGCGCAGCGGGTGATAGGCAAGACCGCGCTGGTGGACGAGGCGGCGATCAAGGCGGCGATGCGCAA
GATCGCCGAGGCCGAGCGTTGGATCGTCGAGGGCGCGGCCGGCGTCGCGATGGCGGGGCTGTTCCAGCTGGCCGAGGCAT
ATCGCGGCCGGCCGGTGGCGGTGGTGCTGTGCGGCCGCAACATCAAGCTGGAGACTTTCCTGGAGGCTTGCCATGAAGCT
GCTTGA

Upstream 100 bases:

>100_bases
ATTGTCTATTTTGTAATTTTTGTCTATATTTGATCCAGGACTTCCACTTACCCGCGGCGGCTGCCCTGCTTCCCGCCGGC
AACTTAAAGGATCCAGGATC

Downstream 100 bases:

>100_bases
CAAGAACGCCATCATCGCGCGCTTCGACGCCGACCATGCGCTGGCCAGGGTGAAGGCCGGCTTCATCGCCTACTCGCGCG
GCCAGGTCCAGTCTGCGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MNDLYQYILDAHRALRPQVAVTPLSHSPALSALTGCEVYLKCEHLQHTGSFKFRGASNKIRLLDAASRRLGVATVSSGNH
GLGVALAGKLAGVPVTVYASAAASEVKLDAIRAHGAKVVVIDAPMLEVELEAARLAERAGLPFVSPYNDVDVIAGQGTIG
MELAEQHPGLVAVFASVGGGGMISGIGSALEMMSPSTEIVGCWPRHSQALYQSMLAGEIVEYEELDTISDGTAGGVEPGA
ITLPIAQRVIGKTALVDEAAIKAAMRKIAEAERWIVEGAAGVAMAGLFQLAEAYRGRPVAVVLCGRNIKLETFLEACHEA
A

Sequences:

>Translated_321_residues
MNDLYQYILDAHRALRPQVAVTPLSHSPALSALTGCEVYLKCEHLQHTGSFKFRGASNKIRLLDAASRRLGVATVSSGNH
GLGVALAGKLAGVPVTVYASAAASEVKLDAIRAHGAKVVVIDAPMLEVELEAARLAERAGLPFVSPYNDVDVIAGQGTIG
MELAEQHPGLVAVFASVGGGGMISGIGSALEMMSPSTEIVGCWPRHSQALYQSMLAGEIVEYEELDTISDGTAGGVEPGA
ITLPIAQRVIGKTALVDEAAIKAAMRKIAEAERWIVEGAAGVAMAGLFQLAEAYRGRPVAVVLCGRNIKLETFLEACHEA
A
>Mature_321_residues
MNDLYQYILDAHRALRPQVAVTPLSHSPALSALTGCEVYLKCEHLQHTGSFKFRGASNKIRLLDAASRRLGVATVSSGNH
GLGVALAGKLAGVPVTVYASAAASEVKLDAIRAHGAKVVVIDAPMLEVELEAARLAERAGLPFVSPYNDVDVIAGQGTIG
MELAEQHPGLVAVFASVGGGGMISGIGSALEMMSPSTEIVGCWPRHSQALYQSMLAGEIVEYEELDTISDGTAGGVEPGA
ITLPIAQRVIGKTALVDEAAIKAAMRKIAEAERWIVEGAAGVAMAGLFQLAEAYRGRPVAVVLCGRNIKLETFLEACHEA
A

Specific function: Acts On Both Serine And Threonine, And Properly Considered As A Hydroxy Amino Acid Deaminase. [C]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=318, Percent_Identity=34.5911949685535, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI19923959, Length=307, Percent_Identity=26.7100977198697, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789505, Length=305, Percent_Identity=31.1475409836066, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790207, Length=292, Percent_Identity=31.1643835616438, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71991565, Length=295, Percent_Identity=31.1864406779661, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17508781, Length=277, Percent_Identity=32.129963898917, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17537387, Length=313, Percent_Identity=32.5878594249201, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322631, Length=309, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320930, Length=269, Percent_Identity=35.6877323420074, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319788, Length=268, Percent_Identity=26.1194029850746, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355833, Length=303, Percent_Identity=35.3135313531353, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645328, Length=216, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014333
- InterPro:   IPR001926
- InterPro:   IPR000634 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33534; Mature: 33534

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLYQYILDAHRALRPQVAVTPLSHSPALSALTGCEVYLKCEHLQHTGSFKFRGASNKI
CCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCEEEEEEEECCCCCCEEEECCCCEE
RLLDAASRRLGVATVSSGNHGLGVALAGKLAGVPVTVYASAAASEVKLDAIRAHGAKVVV
EEEEHHCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEE
IDAPMLEVELEAARLAERAGLPFVSPYNDVDVIAGQGTIGMELAEQHPGLVAVFASVGGG
EECCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCC
GMISGIGSALEMMSPSTEIVGCWPRHSQALYQSMLAGEIVEYEELDTISDGTAGGVEPGA
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCE
ITLPIAQRVIGKTALVDEAAIKAAMRKIAEAERWIVEGAAGVAMAGLFQLAEAYRGRPVA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
VVLCGRNIKLETFLEACHEAA
EEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNDLYQYILDAHRALRPQVAVTPLSHSPALSALTGCEVYLKCEHLQHTGSFKFRGASNKI
CCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCEEEEEEEECCCCCCEEEECCCCEE
RLLDAASRRLGVATVSSGNHGLGVALAGKLAGVPVTVYASAAASEVKLDAIRAHGAKVVV
EEEEHHCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEE
IDAPMLEVELEAARLAERAGLPFVSPYNDVDVIAGQGTIGMELAEQHPGLVAVFASVGGG
EECCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHCCCCEEEEEECCCCC
GMISGIGSALEMMSPSTEIVGCWPRHSQALYQSMLAGEIVEYEELDTISDGTAGGVEPGA
HHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCE
ITLPIAQRVIGKTALVDEAAIKAAMRKIAEAERWIVEGAAGVAMAGLFQLAEAYRGRPVA
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
VVLCGRNIKLETFLEACHEAA
EEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]