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The map label for this gene is accA

Identifier: 34498645

GI number: 34498645

Start: 3471644

End: 3472609

Strand: Reverse

Name: accA

Synonym: CV_3190

Alternate gene names: 34498645

Gene position: 3472609-3471644 (Counterclockwise)

Preceding gene: 34498648

Following gene: 34498644

Centisome position: 73.09

GC content: 61.59

Gene sequence:

>966_bases
ATGAAGCCGACCTTTCTCGATTTTGAGCAGCCGATTGCCGAGCTCGAGAACAAAATTGAAGAGCTGCGTTTCGTGCAGGA
CGACTCCGTGCTGGATATCTCCGAGGAGATCGCCCGTCTGCAGAAGAAGAGTCTGGAACTGACCAAGACTCTATACGCCA
AGCTGACGCCGTCGCAGATCGCGATGGTGGCTCGCCATCCGCAGCGCCCTTATACGCTGGATTACATCCAGGCCATCTTT
ACCGACTTCGAAGAGTTGCACGGCGATCGCGCCTTTGCGGACGATGCCGCCATCGTCGGCGGTCTGGCGCGCTTCAACGG
CCAGTCGGTGATGGTGATCGGCCACCAAAAGGGACGCGACACCAAGGAAAAGATTCGCCGCAATTTCGGCATGCCGCACC
CGGAAGGCTATAGAAAGGCATTGCGCCTGATGAAGCTGGCCGAGAAGTTCGGCATCCCGGTGCTCACCTTCGTCGATACC
ACCGGCGCTTGGCCGGGCATCGGCGCGGAAGAGCGCGGCCAGTCCGAGGCGATCGGCCGCAATCTGTACGAGATGACCAA
TCTGCGCGTGCCCATCGTCGTCACGGTGATCGGCGAGGGCGGTTCCGGCGGCGCGTTGGCCATCGCTGTGGGCGACCACG
TCAACATGCTGCAGTACGCGACTTATTCGGTGATCTCTCCGGAAGGCTGCGCGTCCATTCTGTGGAAGACCGCCGAGCGC
GCGTCCGACGCGGCCGAAGCGCTGGGCATCACCGCGCCGCGCCTGAAGACGCTGGGCCTGATCGACCGCGTGGTCACCGA
GCCGGTGGGCGGCGCCCATCGCGACCATGCTCAGATGATGACCACCTTGAAGCGCGTGCTGCAGGATCAGCTGAAAGAAG
TGCAGTCCAAGCCCATGGATGCGCTGCTGAAAGAACGTTTTGATCGCCTGATGAGCTATGGCCGCTTCAAGGAAGACGCC
GCCTGA

Upstream 100 bases:

>100_bases
TTTGCTCCATTTTTTCAGGTTTTTGCCGGGTCTGCGGGTGACGCCGGCTTCGCGCCTCATGTATCATGCCGCGATTAGGT
TTGACGGATGATTGTAAAGA

Downstream 100 bases:

>100_bases
GCTGGCGGATAGCCTGATCGAGCATTGGCCGGACGAGTTGTCCGGCCTTTTCGCTTTTGAGGTCGGGTTTTCCGGCGGAC
TCGACTCGGTCGCCTTGCTG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKPTFLDFEQPIAELENKIEELRFVQDDSVLDISEEIARLQKKSLELTKTLYAKLTPSQIAMVARHPQRPYTLDYIQAIF
TDFEELHGDRAFADDAAIVGGLARFNGQSVMVIGHQKGRDTKEKIRRNFGMPHPEGYRKALRLMKLAEKFGIPVLTFVDT
TGAWPGIGAEERGQSEAIGRNLYEMTNLRVPIVVTVIGEGGSGGALAIAVGDHVNMLQYATYSVISPEGCASILWKTAER
ASDAAEALGITAPRLKTLGLIDRVVTEPVGGAHRDHAQMMTTLKRVLQDQLKEVQSKPMDALLKERFDRLMSYGRFKEDA
A

Sequences:

>Translated_321_residues
MKPTFLDFEQPIAELENKIEELRFVQDDSVLDISEEIARLQKKSLELTKTLYAKLTPSQIAMVARHPQRPYTLDYIQAIF
TDFEELHGDRAFADDAAIVGGLARFNGQSVMVIGHQKGRDTKEKIRRNFGMPHPEGYRKALRLMKLAEKFGIPVLTFVDT
TGAWPGIGAEERGQSEAIGRNLYEMTNLRVPIVVTVIGEGGSGGALAIAVGDHVNMLQYATYSVISPEGCASILWKTAER
ASDAAEALGITAPRLKTLGLIDRVVTEPVGGAHRDHAQMMTTLKRVLQDQLKEVQSKPMDALLKERFDRLMSYGRFKEDA
A
>Mature_321_residues
MKPTFLDFEQPIAELENKIEELRFVQDDSVLDISEEIARLQKKSLELTKTLYAKLTPSQIAMVARHPQRPYTLDYIQAIF
TDFEELHGDRAFADDAAIVGGLARFNGQSVMVIGHQKGRDTKEKIRRNFGMPHPEGYRKALRLMKLAEKFGIPVLTFVDT
TGAWPGIGAEERGQSEAIGRNLYEMTNLRVPIVVTVIGEGGSGGALAIAVGDHVNMLQYATYSVISPEGCASILWKTAER
ASDAAEALGITAPRLKTLGLIDRVVTEPVGGAHRDHAQMMTTLKRVLQDQLKEVQSKPMDALLKERFDRLMSYGRFKEDA
A

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=64.6687697160883, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_CHRVO (Q7NT71)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902860.1
- ProteinModelPortal:   Q7NT71
- SMR:   Q7NT71
- GeneID:   2548105
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_3190
- NMPDR:   fig|243365.1.peg.3190
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q7NT71
- ProtClustDB:   PRK05724
- BioCyc:   CVIO243365:CV_3190-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35657; Mature: 35657

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTFLDFEQPIAELENKIEELRFVQDDSVLDISEEIARLQKKSLELTKTLYAKLTPSQI
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AMVARHPQRPYTLDYIQAIFTDFEELHGDRAFADDAAIVGGLARFNGQSVMVIGHQKGRD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIRRNFGMPHPEGYRKALRLMKLAEKFGIPVLTFVDTTGAWPGIGAEERGQSEAIGR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCHHHHHH
NLYEMTNLRVPIVVTVIGEGGSGGALAIAVGDHVNMLQYATYSVISPEGCASILWKTAER
HHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASDAAEALGITAPRLKTLGLIDRVVTEPVGGAHRDHAQMMTTLKRVLQDQLKEVQSKPMD
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALLKERFDRLMSYGRFKEDAA
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKPTFLDFEQPIAELENKIEELRFVQDDSVLDISEEIARLQKKSLELTKTLYAKLTPSQI
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AMVARHPQRPYTLDYIQAIFTDFEELHGDRAFADDAAIVGGLARFNGQSVMVIGHQKGRD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIRRNFGMPHPEGYRKALRLMKLAEKFGIPVLTFVDTTGAWPGIGAEERGQSEAIGR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCHHHHHH
NLYEMTNLRVPIVVTVIGEGGSGGALAIAVGDHVNMLQYATYSVISPEGCASILWKTAER
HHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASDAAEALGITAPRLKTLGLIDRVVTEPVGGAHRDHAQMMTTLKRVLQDQLKEVQSKPMD
HHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ALLKERFDRLMSYGRFKEDAA
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782