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The map label for this gene is ubiH [H]

Identifier: 34498576

GI number: 34498576

Start: 3407892

End: 3409061

Strand: Reverse

Name: ubiH [H]

Synonym: CV_3121

Alternate gene names: 34498576

Gene position: 3409061-3407892 (Counterclockwise)

Preceding gene: 34498577

Following gene: 34498575

Centisome position: 71.75

GC content: 71.62

Gene sequence:

>1170_bases
ATGGATTCTACGATGAGTGAACATGCCGATGTGCTGATCGTCGGCGGCGGCCCGGTGGGCGCGCTGGCCGCCTTGAGGCT
GGCGCGGCAGGGCCGCAGCGTGCTGCTGCTGGAGGCGCGCGCGAAAGACGCCGAGGTGCGCGACGCCCGCGCGCTGGCGT
TGTCCTGGCATAGCCGCCGCCTGCTGGAAGAGGCCGGCGCCTGGCCGGCCGACCTGCCGGCCACGGCGATAGACACCGTC
CACGTGTCGCAGCAGGGCGGTTGCGGCCGCACCCGGCTGGACAGCGCGGACCTGGGTCTGCCGCACCTGGGCGCGGTGGT
CGATTACCCGGCCTTGGTCGCTGGCCTGGGCGGCGCGCTGGAGGCGGCGGGCGTGCAGGTGATATGGCAATGCCGGGTGA
CGGCGGTGAAGAGTCTGAGCCAGTACGCATGCGCCGAGGTGGAAACGCCGCAGGGCAAGCAGCTGCTGACCGGCAGCCTG
CTGGTATTGGCCGAGGGCGGCGCGCTGGCTGAGACGCTGCCGGGCATCCGCCGGCTGACACATGATTACCGTCAGTGCGC
GCTGCTGGCCGAGGTGGAGACCGAACTGCCGCCCCAGGGCGTGGCGTACGAGCGCTTCGCCCACGCCGGGCCGTTCGCGC
TGCTGCCGCACGGCGAGCGCTACATGCTGGTGTGGACCCGCAGCCAGGCCGATGCCGAGCGGCTGGCCGCCGCCGACGCG
GCGGTATTGCGCGACGAGCTGCAGCAGGCTTTCGGAGAGCGCCAGGGACGGATATTGTCGATCGGGCCCAGGGCCAGTTT
CCCGCTGGCGCTGCGCCAGGCCAACCGGGTGACCAGCGGGCGGGTGGCGCTGATCGGCAATGCCGCCCAGACCATGCACC
CGGTGGCGGCTCAGGGCCTGAATCTGGGCTTGCGGGATGCGGTCGGCCTGGCCGACGCGCTGGAGAACGCAGCCGACGCC
GGCGACGCGCGCGCGTTGAAGCGCTACGCGGATTCGCGCAAGCTCGACAGCCACGCGGTGGTCGGCTTCACCCATGGCTT
GATCAAGCTGTTCGACGGCCATCACCCGCTGATGAGCCGGCTGCGCGGCGTCGGCATGACGGCGCTGGACGCGCTGCCGT
CCTTGCGGCGCAAATTCGCCGGCCACCTGGTGTTCGGCGTGCGGGGATAA

Upstream 100 bases:

>100_bases
ACAATGTGCTGGTGACCGCGGACGGCAACGAGGTGTATACCGCGGCGGCGCCCAAGACGGTGGCCGGGATCGAGGCGCTG
ATGCGCGGGGAGTAAGGACG

Downstream 100 bases:

>100_bases
ACGATGCGTTACGACAAATATCACGCGGTCGTCGTCGGCGGCGGCCTGGTCGGGGCCAGCCTGGCCCTGGCGCTGGCGCG
CGCCGGCAAGCGGGTGGCGC

Product: 2-octaprenyl-6-methoxyphenol hydroxylase oxidoreductase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDSTMSEHADVLIVGGGPVGALAALRLARQGRSVLLLEARAKDAEVRDARALALSWHSRRLLEEAGAWPADLPATAIDTV
HVSQQGGCGRTRLDSADLGLPHLGAVVDYPALVAGLGGALEAAGVQVIWQCRVTAVKSLSQYACAEVETPQGKQLLTGSL
LVLAEGGALAETLPGIRRLTHDYRQCALLAEVETELPPQGVAYERFAHAGPFALLPHGERYMLVWTRSQADAERLAAADA
AVLRDELQQAFGERQGRILSIGPRASFPLALRQANRVTSGRVALIGNAAQTMHPVAAQGLNLGLRDAVGLADALENAADA
GDARALKRYADSRKLDSHAVVGFTHGLIKLFDGHHPLMSRLRGVGMTALDALPSLRRKFAGHLVFGVRG

Sequences:

>Translated_389_residues
MDSTMSEHADVLIVGGGPVGALAALRLARQGRSVLLLEARAKDAEVRDARALALSWHSRRLLEEAGAWPADLPATAIDTV
HVSQQGGCGRTRLDSADLGLPHLGAVVDYPALVAGLGGALEAAGVQVIWQCRVTAVKSLSQYACAEVETPQGKQLLTGSL
LVLAEGGALAETLPGIRRLTHDYRQCALLAEVETELPPQGVAYERFAHAGPFALLPHGERYMLVWTRSQADAERLAAADA
AVLRDELQQAFGERQGRILSIGPRASFPLALRQANRVTSGRVALIGNAAQTMHPVAAQGLNLGLRDAVGLADALENAADA
GDARALKRYADSRKLDSHAVVGFTHGLIKLFDGHHPLMSRLRGVGMTALDALPSLRRKFAGHLVFGVRG
>Mature_389_residues
MDSTMSEHADVLIVGGGPVGALAALRLARQGRSVLLLEARAKDAEVRDARALALSWHSRRLLEEAGAWPADLPATAIDTV
HVSQQGGCGRTRLDSADLGLPHLGAVVDYPALVAGLGGALEAAGVQVIWQCRVTAVKSLSQYACAEVETPQGKQLLTGSL
LVLAEGGALAETLPGIRRLTHDYRQCALLAEVETELPPQGVAYERFAHAGPFALLPHGERYMLVWTRSQADAERLAAADA
AVLRDELQQAFGERQGRILSIGPRASFPLALRQANRVTSGRVALIGNAAQTMHPVAAQGLNLGLRDAVGLADALENAADA
GDARALKRYADSRKLDSHAVVGFTHGLIKLFDGHHPLMSRLRGVGMTALDALPSLRRKFAGHLVFGVRG

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=405, Percent_Identity=26.1728395061728, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI32967307, Length=244, Percent_Identity=29.0983606557377, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789274, Length=388, Percent_Identity=37.6288659793814, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1789273, Length=387, Percent_Identity=31.0077519379845, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786883, Length=398, Percent_Identity=29.8994974874372, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321694, Length=451, Percent_Identity=24.6119733924612, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 41201; Mature: 41201

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTMSEHADVLIVGGGPVGALAALRLARQGRSVLLLEARAKDAEVRDARALALSWHSRR
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LLEEAGAWPADLPATAIDTVHVSQQGGCGRTRLDSADLGLPHLGAVVDYPALVAGLGGAL
HHHHCCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHH
EAAGVQVIWQCRVTAVKSLSQYACAEVETPQGKQLLTGSLLVLAEGGALAETLPGIRRLT
HHCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
HDYRQCALLAEVETELPPQGVAYERFAHAGPFALLPHGERYMLVWTRSQADAERLAAADA
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHH
AVLRDELQQAFGERQGRILSIGPRASFPLALRQANRVTSGRVALIGNAAQTMHPVAAQGL
HHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCC
NLGLRDAVGLADALENAADAGDARALKRYADSRKLDSHAVVGFTHGLIKLFDGHHPLMSR
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHH
LRGVGMTALDALPSLRRKFAGHLVFGVRG
HHCCCHHHHHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MDSTMSEHADVLIVGGGPVGALAALRLARQGRSVLLLEARAKDAEVRDARALALSWHSRR
CCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LLEEAGAWPADLPATAIDTVHVSQQGGCGRTRLDSADLGLPHLGAVVDYPALVAGLGGAL
HHHHCCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHH
EAAGVQVIWQCRVTAVKSLSQYACAEVETPQGKQLLTGSLLVLAEGGALAETLPGIRRLT
HHCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
HDYRQCALLAEVETELPPQGVAYERFAHAGPFALLPHGERYMLVWTRSQADAERLAAADA
HHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHH
AVLRDELQQAFGERQGRILSIGPRASFPLALRQANRVTSGRVALIGNAAQTMHPVAAQGL
HHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEECHHHHHHHHHHHCC
NLGLRDAVGLADALENAADAGDARALKRYADSRKLDSHAVVGFTHGLIKLFDGHHPLMSR
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCHHHHHH
LRGVGMTALDALPSLRRKFAGHLVFGVRG
HHCCCHHHHHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]