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The map label for this gene is yhcS [C]

Identifier: 34498394

GI number: 34498394

Start: 3215573

End: 3216478

Strand: Direct

Name: yhcS [C]

Synonym: CV_2939

Alternate gene names: 34498394

Gene position: 3215573-3216478 (Clockwise)

Preceding gene: 34498391

Following gene: 34498399

Centisome position: 67.68

GC content: 69.32

Gene sequence:

>906_bases
ATGGACCGACTCACCGCCATGCAAGTCTTCGCCGAAGTTGCCCAGTTGGGCAGCTTCACCGCCGCCGGCGACAAGCTGGA
CATGTCGCGCCCGATGGTCACCCGCTATGTCGAAGAGCTGGAGCAATGGCTGGGCGTGCGGCTGCTGCAGCGTTCCACCC
GCAAGGTCACCCTCACCGACGCCGGCCTCGCCTGCCTGGCCCGCTGCCGGCAGATGCTGGACCTGGCGGACGAAGTGCGG
GCCGACGCCAGCCAGCGCGACGGCCAGGTGCGCGGCTTGCTCAGGGTGGCGGCCAGCACCTCTTTCGGCCTGGCGGTGCT
GGGCGGCGCCGTGGCGGAGTTCGGCGAGCGCCACCCCCAGCTGCGGGTAGACCTGCAGCTGGGCGATCGCGCGGTGAACC
TGATTGAAGAAAGAATAGACCTCGCCATCCGCATTACCAACGAACCGGACCCCGGCCTGGTGGGAAGGCGGCTATGCGAT
TGCCGCTCGCTGCTGGTGGCCGCGCCCTCTTACCTTGCCCGCCACGGCACGCCGAAAGAGCCGGTGGATCTGGAGAGCCA
CCGCTGTCTCAGCTACAGCAATTTCGGCCGCAGCGAATGGCGGTTGCGGAAGGGCGAGGAAGAATCGAAAGTGCGGGTCG
CCGGCAACATCAGCGCCAACGAAGCCAGCGCGCTCCTGAGCGCCACGCTGGCCGGCGCCGGCGTCAGCCTGCAGCCCAGC
TACCTGGCCGCGCCATACGTGCGGCGGGGCGAGCTGGCGGCGCTGCTGCCGGCATGGCAGCCCGCCGTGCTGGGCATTCA
CGCGCTTTACCCATCGCGCCGGCTGCTGCCGCTGTCGCTGCGCAGCCTGCTGGACTTCCTGGTGGAAAAGCTGGGCGGGC
CGGAAGCCCCCTGGGACCGCGGATAA

Upstream 100 bases:

>100_bases
TGCACTGCGTTTCAGTGAGGATGCGCACACTATAAGCGCAATAATCGATCCAATAAATCGGCTAAACTGCACATTATTGT
TTCTTAAATCGTGCAAATAA

Downstream 100 bases:

>100_bases
CTCGGGCCCCGCCGGCGGGCTCAGCCTTGAAAAGCCTCGCGATGGGAAATCGCGGGGAAGCTGCGTTCGGCCGCGCGCGG
CATCCGGCATCCCTGGCAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDRLTAMQVFAEVAQLGSFTAAGDKLDMSRPMVTRYVEELEQWLGVRLLQRSTRKVTLTDAGLACLARCRQMLDLADEVR
ADASQRDGQVRGLLRVAASTSFGLAVLGGAVAEFGERHPQLRVDLQLGDRAVNLIEERIDLAIRITNEPDPGLVGRRLCD
CRSLLVAAPSYLARHGTPKEPVDLESHRCLSYSNFGRSEWRLRKGEEESKVRVAGNISANEASALLSATLAGAGVSLQPS
YLAAPYVRRGELAALLPAWQPAVLGIHALYPSRRLLPLSLRSLLDFLVEKLGGPEAPWDRG

Sequences:

>Translated_301_residues
MDRLTAMQVFAEVAQLGSFTAAGDKLDMSRPMVTRYVEELEQWLGVRLLQRSTRKVTLTDAGLACLARCRQMLDLADEVR
ADASQRDGQVRGLLRVAASTSFGLAVLGGAVAEFGERHPQLRVDLQLGDRAVNLIEERIDLAIRITNEPDPGLVGRRLCD
CRSLLVAAPSYLARHGTPKEPVDLESHRCLSYSNFGRSEWRLRKGEEESKVRVAGNISANEASALLSATLAGAGVSLQPS
YLAAPYVRRGELAALLPAWQPAVLGIHALYPSRRLLPLSLRSLLDFLVEKLGGPEAPWDRG
>Mature_301_residues
MDRLTAMQVFAEVAQLGSFTAAGDKLDMSRPMVTRYVEELEQWLGVRLLQRSTRKVTLTDAGLACLARCRQMLDLADEVR
ADASQRDGQVRGLLRVAASTSFGLAVLGGAVAEFGERHPQLRVDLQLGDRAVNLIEERIDLAIRITNEPDPGLVGRRLCD
CRSLLVAAPSYLARHGTPKEPVDLESHRCLSYSNFGRSEWRLRKGEEESKVRVAGNISANEASALLSATLAGAGVSLQPS
YLAAPYVRRGELAALLPAWQPAVLGIHALYPSRRLLPLSLRSLLDFLVEKLGGPEAPWDRG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=36.0544217687075, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=30.1694915254237, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=29.9651567944251, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=31.4878892733564, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI145693193, Length=283, Percent_Identity=31.4487632508834, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=29.2682926829268, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=26.7148014440433, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788706, Length=257, Percent_Identity=26.8482490272374, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788748, Length=177, Percent_Identity=35.0282485875706, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787601, Length=135, Percent_Identity=30.3703703703704, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693105, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=25.6, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI157672245, Length=121, Percent_Identity=35.5371900826446, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32919; Mature: 32919

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLTAMQVFAEVAQLGSFTAAGDKLDMSRPMVTRYVEELEQWLGVRLLQRSTRKVTLTD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
AGLACLARCRQMLDLADEVRADASQRDGQVRGLLRVAASTSFGLAVLGGAVAEFGERHPQ
HHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LRVDLQLGDRAVNLIEERIDLAIRITNEPDPGLVGRRLCDCRSLLVAAPSYLARHGTPKE
EEEEEECCHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVDLESHRCLSYSNFGRSEWRLRKGEEESKVRVAGNISANEASALLSATLAGAGVSLQPS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCH
YLAAPYVRRGELAALLPAWQPAVLGIHALYPSRRLLPLSLRSLLDFLVEKLGGPEAPWDR
HHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
G
C
>Mature Secondary Structure
MDRLTAMQVFAEVAQLGSFTAAGDKLDMSRPMVTRYVEELEQWLGVRLLQRSTRKVTLTD
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEH
AGLACLARCRQMLDLADEVRADASQRDGQVRGLLRVAASTSFGLAVLGGAVAEFGERHPQ
HHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LRVDLQLGDRAVNLIEERIDLAIRITNEPDPGLVGRRLCDCRSLLVAAPSYLARHGTPKE
EEEEEECCHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVDLESHRCLSYSNFGRSEWRLRKGEEESKVRVAGNISANEASALLSATLAGAGVSLQPS
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCH
YLAAPYVRRGELAALLPAWQPAVLGIHALYPSRRLLPLSLRSLLDFLVEKLGGPEAPWDR
HHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]