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The map label for this gene is xylR [H]

Identifier: 34498350

GI number: 34498350

Start: 3171953

End: 3173164

Strand: Reverse

Name: xylR [H]

Synonym: CV_2895

Alternate gene names: 34498350

Gene position: 3173164-3171953 (Counterclockwise)

Preceding gene: 34498355

Following gene: 34498349

Centisome position: 66.79

GC content: 70.54

Gene sequence:

>1212_bases
ATGAGAAAAGCCCCCTCCAGCGCCGGGCCGAACATGGTGTCCGGTACCAATCTCGAGCACGCCCGCTCGCACAACCGCCG
CGCGGTGCTGGAAACCGTGCGTTTGAACGGCCAGCTGACCCGGGCCGATCTGGCGCGCTTGACCGCGCTGACGCCGCAGA
CGGTGTCCAATATCGCCGCGGAACTGTTGGACGCCGGCATGCTGCTGGCGGGCGAGCCGCTGCGCGAGGGCGGCCGCGGC
CAGCCGGCGATTCCGCTCAGCCTGAATCCGGATGGTGCCTACGCGGTCGGGATGCAACTGGATCACCAGATGCTGGTGGC
GCTGGCGCTGGATCTGTCGGGCCAGGCGCGGTTCCGGCTGGAGCTGGCGGTGGACCGCCCGACGCCGGATGAGGCCTTGC
CGCTGATCGCCGGCCTGCTGCAGCGCTTGAGGCAGGAGTCAGGCTTGGATTGGGGGCGCTTGCTGGGGCTGGGGCTGGTG
ATGCCGGGGCCGTTCGGGGTGGAGGGCATGACCTCGGTCGGGCCGACCACGCTGCCGGGATGGGAGGGCGTGGATTCGGC
TTCGTTGACGCGCGCGCTGGGCTTGCCGGTGCTGCTGGAGAAGGATGCCACCGCCGCGGCGATAGGCGAGCGGCTGTACG
GCACGGCCAGCACGCTGCGCAATTTCGTCTATCTGTTCGTCGGCGCGGGTTTGGGCGCAGGCCTGTTTCTGGACGGCCGC
TTGTACACCGGCGGCCGGCGCAACGCCGGCGAGGTGGGACACATGATGGTGGTGCCGGACGGGCGGCCTTGCGATTGCGG
CAACCGCGGCTGCCTGGAGCGCTATGTGTCGCTGCAGGCGCTGTACGAGGCGCTGGGCATCGCCGGCGGGCCGCTCGCCA
CGCCAGAGCACCTGGCGGGCCGCGGCATCGATGCCGCCGGCCAGCGCTGGCTGGATGCCGCCGCGGGGCCGCTGAGGCAG
GCGATCAATATCCTGGAGTCTTTGCTGGACATCGACGCCGTGGTGTTGGGCGGGTTGCTGCCTCCGGCCTGGCAGGAGGC
GCTGCTGGCGCGCTTGCACCCGCTGCCGCTGTCGGTGCGCAGCAGCAGCGGCGACAGGCTGAGGCTGGGCAGCGCCGGGC
GCGACGTGGTGGCGCTGGGCGCGGCGGCCCTGCTGGTATTCGATGAATTCAACCCGCAATACGAGGTGTTGTTGAAGAAC
GGCCGGCGCTGA

Upstream 100 bases:

>100_bases
GTAAAGCATTCGAAATTTATTTCGTCAACTTGATTTATTTAAATGCAAGGAAATGACAACGGCTTGTGTGTGGCGGGGCG
CGAAGTCATACTCCCGTCTC

Downstream 100 bases:

>100_bases
GCGTTCGGCGCGCGTGATCAGACTGGAGGGCGACGATGGCGATGCGGTTCCTGTTCAATCATCTGGGCTTCGAGAGCGCG
GCGGCCAAGCCGGCGCTGCT

Product: transcriptional regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MRKAPSSAGPNMVSGTNLEHARSHNRRAVLETVRLNGQLTRADLARLTALTPQTVSNIAAELLDAGMLLAGEPLREGGRG
QPAIPLSLNPDGAYAVGMQLDHQMLVALALDLSGQARFRLELAVDRPTPDEALPLIAGLLQRLRQESGLDWGRLLGLGLV
MPGPFGVEGMTSVGPTTLPGWEGVDSASLTRALGLPVLLEKDATAAAIGERLYGTASTLRNFVYLFVGAGLGAGLFLDGR
LYTGGRRNAGEVGHMMVVPDGRPCDCGNRGCLERYVSLQALYEALGIAGGPLATPEHLAGRGIDAAGQRWLDAAAGPLRQ
AINILESLLDIDAVVLGGLLPPAWQEALLARLHPLPLSVRSSSGDRLRLGSAGRDVVALGAAALLVFDEFNPQYEVLLKN
GRR

Sequences:

>Translated_403_residues
MRKAPSSAGPNMVSGTNLEHARSHNRRAVLETVRLNGQLTRADLARLTALTPQTVSNIAAELLDAGMLLAGEPLREGGRG
QPAIPLSLNPDGAYAVGMQLDHQMLVALALDLSGQARFRLELAVDRPTPDEALPLIAGLLQRLRQESGLDWGRLLGLGLV
MPGPFGVEGMTSVGPTTLPGWEGVDSASLTRALGLPVLLEKDATAAAIGERLYGTASTLRNFVYLFVGAGLGAGLFLDGR
LYTGGRRNAGEVGHMMVVPDGRPCDCGNRGCLERYVSLQALYEALGIAGGPLATPEHLAGRGIDAAGQRWLDAAAGPLRQ
AINILESLLDIDAVVLGGLLPPAWQEALLARLHPLPLSVRSSSGDRLRLGSAGRDVVALGAAALLVFDEFNPQYEVLLKN
GRR
>Mature_403_residues
MRKAPSSAGPNMVSGTNLEHARSHNRRAVLETVRLNGQLTRADLARLTALTPQTVSNIAAELLDAGMLLAGEPLREGGRG
QPAIPLSLNPDGAYAVGMQLDHQMLVALALDLSGQARFRLELAVDRPTPDEALPLIAGLLQRLRQESGLDWGRLLGLGLV
MPGPFGVEGMTSVGPTTLPGWEGVDSASLTRALGLPVLLEKDATAAAIGERLYGTASTLRNFVYLFVGAGLGAGLFLDGR
LYTGGRRNAGEVGHMMVVPDGRPCDCGNRGCLERYVSLQALYEALGIAGGPLATPEHLAGRGIDAAGQRWLDAAAGPLRQ
AINILESLLDIDAVVLGGLLPPAWQEALLARLHPLPLSVRSSSGDRLRLGSAGRDVVALGAAALLVFDEFNPQYEVLLKN
GRR

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4885285, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI298566325, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI190014632, Length=202, Percent_Identity=31.6831683168317, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787878, Length=276, Percent_Identity=27.8985507246377, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082127, Length=348, Percent_Identity=27.2988505747126, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786891, Length=267, Percent_Identity=23.5955056179775, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787363, Length=270, Percent_Identity=31.1111111111111, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081733, Length=192, Percent_Identity=26.5625, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 42445; Mature: 42445

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAPSSAGPNMVSGTNLEHARSHNRRAVLETVRLNGQLTRADLARLTALTPQTVSNIAA
CCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHH
ELLDAGMLLAGEPLREGGRGQPAIPLSLNPDGAYAVGMQLDHQMLVALALDLSGQARFRL
HHHHCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCEEEE
ELAVDRPTPDEALPLIAGLLQRLRQESGLDWGRLLGLGLVMPGPFGVEGMTSVGPTTLPG
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WEGVDSASLTRALGLPVLLEKDATAAAIGERLYGTASTLRNFVYLFVGAGLGAGLFLDGR
CCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCE
LYTGGRRNAGEVGHMMVVPDGRPCDCGNRGCLERYVSLQALYEALGIAGGPLATPEHLAG
EECCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHC
RGIDAAGQRWLDAAAGPLRQAINILESLLDIDAVVLGGLLPPAWQEALLARLHPLPLSVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
SSSGDRLRLGSAGRDVVALGAAALLVFDEFNPQYEVLLKNGRR
CCCCCEEEECCCCCCHHHHHHHHEEEECCCCCCEEHHCCCCCC
>Mature Secondary Structure
MRKAPSSAGPNMVSGTNLEHARSHNRRAVLETVRLNGQLTRADLARLTALTPQTVSNIAA
CCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHH
ELLDAGMLLAGEPLREGGRGQPAIPLSLNPDGAYAVGMQLDHQMLVALALDLSGQARFRL
HHHHCCCCCCCCHHHCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCEEEE
ELAVDRPTPDEALPLIAGLLQRLRQESGLDWGRLLGLGLVMPGPFGVEGMTSVGPTTLPG
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WEGVDSASLTRALGLPVLLEKDATAAAIGERLYGTASTLRNFVYLFVGAGLGAGLFLDGR
CCCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECCE
LYTGGRRNAGEVGHMMVVPDGRPCDCGNRGCLERYVSLQALYEALGIAGGPLATPEHLAG
EECCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHC
RGIDAAGQRWLDAAAGPLRQAINILESLLDIDAVVLGGLLPPAWQEALLARLHPLPLSVR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
SSSGDRLRLGSAGRDVVALGAAALLVFDEFNPQYEVLLKNGRR
CCCCCEEEECCCCCCHHHHHHHHEEEECCCCCCEEHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]