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The map label for this gene is speA

Identifier: 34498331

GI number: 34498331

Start: 3150773

End: 3152653

Strand: Reverse

Name: speA

Synonym: CV_2876

Alternate gene names: 34498331

Gene position: 3152653-3150773 (Counterclockwise)

Preceding gene: 34498333

Following gene: 34498328

Centisome position: 66.36

GC content: 63.96

Gene sequence:

>1881_bases
ATGGCTTGGTCTGTGGCTGATAGCCGGAGCCTGTACGGCATCCGGCATTGGGGGGCTGGTTATTTCGATGTCGGGGACAG
CGGCAACATCGTCGTGCGTCCCAATGTGCGCCAGCGCAAGGAAATCGATCTGTACCGCCTGGTGCGCGATCTGGGCGGCA
AAGGCCTGGATCTGCCTCTTCTGGTCCGTTTCCCGGACATTCTGCAGGACCGCGTGACCCGCCTGTGCGGCGCCTTCGAC
AAGGCCATCGCCGAACAGGGCTACGGCAACCGCTACACCGCCATCTACCCGATCAAGGTCAACCAGCAGGAAGCGGTGGT
CAAGAGCATCATCGCCACCCAGGACGTGTCCATCGGCCTGGAAGCCGGCTCCAAGCCGGAGCTGATGGCGGTGCTGGCCT
TGGCGCCCAAGGGCTGCACCATCGTCTGCAACGGCTACAAGGACCGCGAATTCATCCGTCTCGCGCTGATCGGCGAGCGC
CTGGGCCACCAGGTGTTCATCGTGATCGAGAAGGAGTCCGAGGTCGATCTGGTGATCGAGGAATCCCGCAAGCTGGAAGT
GCGCCCCAATATCGGCCTGCGCGTGCGCCTGTCGTCGCTGGCGTCCAGCAAGTGGTCCGACACCGGCGGGGAAAAGGGCA
AGTTCGGCCTGTCCGCCGGCCAACTGATCTCGGCCACCGACAAGCTGATCGCGGCCGGCCTGGGCGACTGCGTGCGCCTG
ATGCACTTCCACATGGGTTCGCAGATCGCCAACATCGCAGATTACCGCCTGGGCTTCCGCGAAGCGATCCGCTACTTCGC
CGAGCTGCGCGCGCTGGGCCTGCCGGTCGACCATGTCGACGTCGGCGGCGGCCTGGGCGTCGATTACGACGGCACCCACT
CGCGCAACGACAGTTCGATCAACTACGACATGGCCGAATACGCGCACGTGATCGTGTCCATGCTGTCCGAGTTCTGCGCC
GAGAACGGCATCCCGCACCCGCGCATCCTGTCCGAATCCGGCCGCGCGATGACCGCCCACCACGCGGTACTGCTGATGAA
CGTGACCGATGTCGAGCGCCTGCCCGACACAGTGGCGCCGATCGACAAAGCGGAAGAGCTGTCGCTGCCACTGCGCAAGC
TGGTGGAGCTGGCCAACCTCAATGACGAGGAGCTGGTCACCGAGATCTACTACCGCGCCAGCCACTGCGTGTCGGAAGTG
AGCGAGATGTACGCCGAAGGCCGTCTGTCGCTGCAGGAAAAGGCGCTGGCCGAAGACCTGCACGCCACGCTGTGCCGCCG
TCTGCACAACCAGCTGCAGGCCAGCCAGCGCTCGCAGCGCCAGGTGTACGATGAACTGACCGACCGTCTGGCCGACAAGT
ATTTCTGCAACTTCTCCGTGTTCCAGAGCTTGCCGGACACCTGGGCCATCGATCAGGTGCTGCCCATCATGCCGGTGCAT
CGCCTGGCCGAGCAGCCGACCCGCCGCGCGGTGCTGCAGGACCTGACCTGCGACTCCGACGGCAAGCTGAAGCAGTACGT
CGACCAGCAGAGCATCGAGTCCAGCATGTCGGTGCACGAAGTGAAGCAGGGCGACGAGTACCTGATCGCGGTGTTCCTGG
TGGGCGCCTACCAGGAAATCCTGGGCGACATGCACAACCTGTTCGGCGATACCGACTCGGTCAACGTCTACGTCCGCGAG
GGCGGCGAGCTGGAGATTTCCGGCATCGAGGAACACGATACCATCGAGGACATGCTGCGCTATGTGCACCTGTCGCCGGA
GGACCTGCTCAACCGCTACGAGGCCAAGACCCGCGAATGCGATCTGAACCCGGAAGAGCGCAGCCTGTACTTCGCCGAAT
TCTGCCGCGGCCTGAAGCAGTCGTCTTACCTGGCGGTCTGA

Upstream 100 bases:

>100_bases
GTTTCGCTCCGACATCCCAGGCCCACATAAAAGCTGTAGAGCCCGAAAGCCGTGCACTAAGGAGCGGGGTTATCCATCAT
AAGTTCTGAGAGGAAAACTC

Downstream 100 bases:

>100_bases
TTTCCGCATCCGCGTATTGAAAAACCGGGCCTTGGCCCGGTTTTTTTGCGTCTGAAGCGTCCTCAGCCCGGTTCGGAGCC
GGAAGGGACGAAATACAGGC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MAWSVADSRSLYGIRHWGAGYFDVGDSGNIVVRPNVRQRKEIDLYRLVRDLGGKGLDLPLLVRFPDILQDRVTRLCGAFD
KAIAEQGYGNRYTAIYPIKVNQQEAVVKSIIATQDVSIGLEAGSKPELMAVLALAPKGCTIVCNGYKDREFIRLALIGER
LGHQVFIVIEKESEVDLVIEESRKLEVRPNIGLRVRLSSLASSKWSDTGGEKGKFGLSAGQLISATDKLIAAGLGDCVRL
MHFHMGSQIANIADYRLGFREAIRYFAELRALGLPVDHVDVGGGLGVDYDGTHSRNDSSINYDMAEYAHVIVSMLSEFCA
ENGIPHPRILSESGRAMTAHHAVLLMNVTDVERLPDTVAPIDKAEELSLPLRKLVELANLNDEELVTEIYYRASHCVSEV
SEMYAEGRLSLQEKALAEDLHATLCRRLHNQLQASQRSQRQVYDELTDRLADKYFCNFSVFQSLPDTWAIDQVLPIMPVH
RLAEQPTRRAVLQDLTCDSDGKLKQYVDQQSIESSMSVHEVKQGDEYLIAVFLVGAYQEILGDMHNLFGDTDSVNVYVRE
GGELEISGIEEHDTIEDMLRYVHLSPEDLLNRYEAKTRECDLNPEERSLYFAEFCRGLKQSSYLAV

Sequences:

>Translated_626_residues
MAWSVADSRSLYGIRHWGAGYFDVGDSGNIVVRPNVRQRKEIDLYRLVRDLGGKGLDLPLLVRFPDILQDRVTRLCGAFD
KAIAEQGYGNRYTAIYPIKVNQQEAVVKSIIATQDVSIGLEAGSKPELMAVLALAPKGCTIVCNGYKDREFIRLALIGER
LGHQVFIVIEKESEVDLVIEESRKLEVRPNIGLRVRLSSLASSKWSDTGGEKGKFGLSAGQLISATDKLIAAGLGDCVRL
MHFHMGSQIANIADYRLGFREAIRYFAELRALGLPVDHVDVGGGLGVDYDGTHSRNDSSINYDMAEYAHVIVSMLSEFCA
ENGIPHPRILSESGRAMTAHHAVLLMNVTDVERLPDTVAPIDKAEELSLPLRKLVELANLNDEELVTEIYYRASHCVSEV
SEMYAEGRLSLQEKALAEDLHATLCRRLHNQLQASQRSQRQVYDELTDRLADKYFCNFSVFQSLPDTWAIDQVLPIMPVH
RLAEQPTRRAVLQDLTCDSDGKLKQYVDQQSIESSMSVHEVKQGDEYLIAVFLVGAYQEILGDMHNLFGDTDSVNVYVRE
GGELEISGIEEHDTIEDMLRYVHLSPEDLLNRYEAKTRECDLNPEERSLYFAEFCRGLKQSSYLAV
>Mature_625_residues
AWSVADSRSLYGIRHWGAGYFDVGDSGNIVVRPNVRQRKEIDLYRLVRDLGGKGLDLPLLVRFPDILQDRVTRLCGAFDK
AIAEQGYGNRYTAIYPIKVNQQEAVVKSIIATQDVSIGLEAGSKPELMAVLALAPKGCTIVCNGYKDREFIRLALIGERL
GHQVFIVIEKESEVDLVIEESRKLEVRPNIGLRVRLSSLASSKWSDTGGEKGKFGLSAGQLISATDKLIAAGLGDCVRLM
HFHMGSQIANIADYRLGFREAIRYFAELRALGLPVDHVDVGGGLGVDYDGTHSRNDSSINYDMAEYAHVIVSMLSEFCAE
NGIPHPRILSESGRAMTAHHAVLLMNVTDVERLPDTVAPIDKAEELSLPLRKLVELANLNDEELVTEIYYRASHCVSEVS
EMYAEGRLSLQEKALAEDLHATLCRRLHNQLQASQRSQRQVYDELTDRLADKYFCNFSVFQSLPDTWAIDQVLPIMPVHR
LAEQPTRRAVLQDLTCDSDGKLKQYVDQQSIESSMSVHEVKQGDEYLIAVFLVGAYQEILGDMHNLFGDTDSVNVYVREG
GELEISGIEEHDTIEDMLRYVHLSPEDLLNRYEAKTRECDLNPEERSLYFAEFCRGLKQSSYLAV

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=621, Percent_Identity=45.2495974235105, Blast_Score=547, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_CHRVO (Q7NU27)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902546.1
- ProteinModelPortal:   Q7NU27
- GeneID:   2548774
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2876
- NMPDR:   fig|243365.1.peg.2876
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- PhylomeDB:   Q7NU27
- ProtClustDB:   PRK05354
- BioCyc:   CVIO243365:CV_2876-MONOMER
- BRENDA:   4.1.1.19
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC; SSF50621 Racem_decarbox_C

EC number: =4.1.1.19

Molecular weight: Translated: 70120; Mature: 69988

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWSVADSRSLYGIRHWGAGYFDVGDSGNIVVRPNVRQRKEIDLYRLVRDLGGKGLDLPL
CCCCCCCCCCCCEEHCCCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCE
LVRFPDILQDRVTRLCGAFDKAIAEQGYGNRYTAIYPIKVNQQEAVVKSIIATQDVSIGL
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCEEEC
EAGSKPELMAVLALAPKGCTIVCNGYKDREFIRLALIGERLGHQVFIVIEKESEVDLVIE
CCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
ESRKLEVRPNIGLRVRLSSLASSKWSDTGGEKGKFGLSAGQLISATDKLIAAGLGDCVRL
CCCCEEECCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MHFHMGSQIANIADYRLGFREAIRYFAELRALGLPVDHVDVGGGLGVDYDGTHSRNDSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
NYDMAEYAHVIVSMLSEFCAENGIPHPRILSESGRAMTAHHAVLLMNVTDVERLPDTVAP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEECHHHHHCCCHHCC
IDKAEELSLPLRKLVELANLNDEELVTEIYYRASHCVSEVSEMYAEGRLSLQEKALAEDL
CCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
HATLCRRLHNQLQASQRSQRQVYDELTDRLADKYFCNFSVFQSLPDTWAIDQVLPIMPVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHH
RLAEQPTRRAVLQDLTCDSDGKLKQYVDQQSIESSMSVHEVKQGDEYLIAVFLVGAYQEI
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LGDMHNLFGDTDSVNVYVREGGELEISGIEEHDTIEDMLRYVHLSPEDLLNRYEAKTREC
HHHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DLNPEERSLYFAEFCRGLKQSSYLAV
CCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AWSVADSRSLYGIRHWGAGYFDVGDSGNIVVRPNVRQRKEIDLYRLVRDLGGKGLDLPL
CCCCCCCCCCCEEHCCCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCE
LVRFPDILQDRVTRLCGAFDKAIAEQGYGNRYTAIYPIKVNQQEAVVKSIIATQDVSIGL
EECCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHHCCCEEEC
EAGSKPELMAVLALAPKGCTIVCNGYKDREFIRLALIGERLGHQVFIVIEKESEVDLVIE
CCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE
ESRKLEVRPNIGLRVRLSSLASSKWSDTGGEKGKFGLSAGQLISATDKLIAAGLGDCVRL
CCCCEEECCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
MHFHMGSQIANIADYRLGFREAIRYFAELRALGLPVDHVDVGGGLGVDYDGTHSRNDSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
NYDMAEYAHVIVSMLSEFCAENGIPHPRILSESGRAMTAHHAVLLMNVTDVERLPDTVAP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEECHHHHHCCCHHCC
IDKAEELSLPLRKLVELANLNDEELVTEIYYRASHCVSEVSEMYAEGRLSLQEKALAEDL
CCCHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
HATLCRRLHNQLQASQRSQRQVYDELTDRLADKYFCNFSVFQSLPDTWAIDQVLPIMPVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHH
RLAEQPTRRAVLQDLTCDSDGKLKQYVDQQSIESSMSVHEVKQGDEYLIAVFLVGAYQEI
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LGDMHNLFGDTDSVNVYVREGGELEISGIEEHDTIEDMLRYVHLSPEDLLNRYEAKTREC
HHHHHHHCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DLNPEERSLYFAEFCRGLKQSSYLAV
CCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782