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The map label for this gene is shlB [H]

Identifier: 34498328

GI number: 34498328

Start: 3146472

End: 3148160

Strand: Reverse

Name: shlB [H]

Synonym: CV_2873

Alternate gene names: 34498328

Gene position: 3148160-3146472 (Counterclockwise)

Preceding gene: 34498331

Following gene: 34498327

Centisome position: 66.26

GC content: 69.75

Gene sequence:

>1689_bases
ATGAACTTTGTCATAAAGGCCGCCTGCATGGGCGGCTTGCTCTTTCCCGCCTGGGCCGCCGCTACCGTGCCGGACGCGGT
GCTGCAACAGAACGACCAACAACTCCGCCATCAGCAACAACAGCTGGAGCAACGCCGCCAGGAGCTGCAACAGCGGCCGG
ATGTGTTCTCCCCAACGCCGGCGACATCACCGCAGACAGCTCTTCCCGCTTCCGATGCGCAGCACTGTTTTACTCTGAGC
CGGGTGTCGCTGGAAGGTGCGCCCGCCGGCTGGCTGGCCTGGCTGCAGCCGCTGGCTGACGCCGGCCTGGCCGGCTGCGT
CGACCTGGCCCGGATCAACGGCCTGACGGCAGCGCTCACCAACGAGATGGTGGCGCGTGGCTTCGTCACCAGCCGGGTCT
ACCTGCCGGAACAGAACCTGCGCGGCGGCCAACTGCGGCTGGCGGTGGTGCCCGGCCGTATCCACGCGATCCAGCTGAAA
GCGGGCGGCAGCGACATCGGCCTGCGCAGCGCTTTCCCGGCCGTGGCCGGCGACATCCTCAATGTGCGCGACCTGGAACA
GGGCCTGGAGCAGTTGGGCCGGGTGCCGGGCCAGCAGGCGACGATGGAGCTGACGCCGGCCGACGCGCCGGGCGAAAGCG
ACGTGGTGGTGGACCGCGGCGGCGGCCGTCTGCTGTCAGGCCTGCTGTCGCTGGACGATTCCGGCCAGAACGCCACCGGA
CGGCTGCAAACCTCCGGCAGCCTGACGCTAGGCGGCGCCACCGGCCTCAACGACGCGCTGTCGCTGTCCTGGAGCCAGGA
CGCCGAGCATCTGGCGCATCCGCTGAGCCAGTCGGCGTCGCTGTCCTGGCTGCTGCCGCTGGGCAACTGGACCGGTTTTT
TCAGCTACAGCGGCTTCGCCTACCACCAGACGGTGCAGGGAGTGAACCAGAGCTTCACCTCCAGCGGCCACAGCCGCAAC
ACCCTGCTGTCGCTATCGCGGCTGCTGCGGCGCAATCAGAGCGGCAAGACCGAACTGAAGCTGAGCCTGACGCGCAAGGC
GTCGCGCAGCTTCGTCGAGGATGCCGAGGTGGCGCAGCAGCGGCGCGACCTGACCATCGCCGGGCTGGAGCTCAGCCATC
GCCAGTATCTGGGCGAGGCGGTGCTGGATGGCTCGATCAGCTACCAGCGCGGCATCGGCGCCTGGGGCGCGCAGCCGGAT
ACGCTGGCGGCGCAGGGCGGCCCGACCGCCCGCCACCAGCTGTACCAGGGCCGGCTGGCGCTGCAGCTGCCGCTGCATAT
CGCGTCGCAGACGCTGCGCTGGAGCAGCGAGCTGCGCGGCCAGTACAGCCCGGACCTGCTGATGTCCAGCGAGCAGTTCG
CCATCGGCGGCCGCGGCAGCGTGCGCGGCTTCAATACCAGTACGCTGGTGGGGCAGAGCGGCTATTACCTGCGCAACGAG
CTGAGTTGGCCGCTGCCGCAGCTGCAAGGCTTGGCGCTGGAGCCCTACCTGGGGTTGGACGCCGGCCAGATCGCCCGCCC
GGCTTACGACGCCGGCCCGGACCGCAGCCTGTCCGGCTGGGCCGCCGGCCTGCGCCTGAGCCTGGGCGGCCATCTGTCCG
CCGAACTCAGCCACGAGCGCGCGCTGCACCAGCCGCAGGGCTGGGATCGTCCCGCCATCACCCATTTCTCGATCACCGCG
CAGTGGTGA

Upstream 100 bases:

>100_bases
CAAGAAAATAAGTAATTTTACGTAATCGGAAATGTAATCAAATTGTTAATATTTGCGGCAGTATTTTTAATAATTTTAAA
TATTCACTCTGATTGCCGCG

Downstream 100 bases:

>100_bases
GCCCGCTGCCCTGTCCCGTCTTATTGAGCTGACATCATGAACAAACACCTTTATCGGATCATCTTCAACCAATCCCGCGG
CCAACTGATGGTGGTGCAGG

Product: hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MNFVIKAACMGGLLFPAWAAATVPDAVLQQNDQQLRHQQQQLEQRRQELQQRPDVFSPTPATSPQTALPASDAQHCFTLS
RVSLEGAPAGWLAWLQPLADAGLAGCVDLARINGLTAALTNEMVARGFVTSRVYLPEQNLRGGQLRLAVVPGRIHAIQLK
AGGSDIGLRSAFPAVAGDILNVRDLEQGLEQLGRVPGQQATMELTPADAPGESDVVVDRGGGRLLSGLLSLDDSGQNATG
RLQTSGSLTLGGATGLNDALSLSWSQDAEHLAHPLSQSASLSWLLPLGNWTGFFSYSGFAYHQTVQGVNQSFTSSGHSRN
TLLSLSRLLRRNQSGKTELKLSLTRKASRSFVEDAEVAQQRRDLTIAGLELSHRQYLGEAVLDGSISYQRGIGAWGAQPD
TLAAQGGPTARHQLYQGRLALQLPLHIASQTLRWSSELRGQYSPDLLMSSEQFAIGGRGSVRGFNTSTLVGQSGYYLRNE
LSWPLPQLQGLALEPYLGLDAGQIARPAYDAGPDRSLSGWAAGLRLSLGGHLSAELSHERALHQPQGWDRPAITHFSITA
QW

Sequences:

>Translated_562_residues
MNFVIKAACMGGLLFPAWAAATVPDAVLQQNDQQLRHQQQQLEQRRQELQQRPDVFSPTPATSPQTALPASDAQHCFTLS
RVSLEGAPAGWLAWLQPLADAGLAGCVDLARINGLTAALTNEMVARGFVTSRVYLPEQNLRGGQLRLAVVPGRIHAIQLK
AGGSDIGLRSAFPAVAGDILNVRDLEQGLEQLGRVPGQQATMELTPADAPGESDVVVDRGGGRLLSGLLSLDDSGQNATG
RLQTSGSLTLGGATGLNDALSLSWSQDAEHLAHPLSQSASLSWLLPLGNWTGFFSYSGFAYHQTVQGVNQSFTSSGHSRN
TLLSLSRLLRRNQSGKTELKLSLTRKASRSFVEDAEVAQQRRDLTIAGLELSHRQYLGEAVLDGSISYQRGIGAWGAQPD
TLAAQGGPTARHQLYQGRLALQLPLHIASQTLRWSSELRGQYSPDLLMSSEQFAIGGRGSVRGFNTSTLVGQSGYYLRNE
LSWPLPQLQGLALEPYLGLDAGQIARPAYDAGPDRSLSGWAAGLRLSLGGHLSAELSHERALHQPQGWDRPAITHFSITA
QW
>Mature_562_residues
MNFVIKAACMGGLLFPAWAAATVPDAVLQQNDQQLRHQQQQLEQRRQELQQRPDVFSPTPATSPQTALPASDAQHCFTLS
RVSLEGAPAGWLAWLQPLADAGLAGCVDLARINGLTAALTNEMVARGFVTSRVYLPEQNLRGGQLRLAVVPGRIHAIQLK
AGGSDIGLRSAFPAVAGDILNVRDLEQGLEQLGRVPGQQATMELTPADAPGESDVVVDRGGGRLLSGLLSLDDSGQNATG
RLQTSGSLTLGGATGLNDALSLSWSQDAEHLAHPLSQSASLSWLLPLGNWTGFFSYSGFAYHQTVQGVNQSFTSSGHSRN
TLLSLSRLLRRNQSGKTELKLSLTRKASRSFVEDAEVAQQRRDLTIAGLELSHRQYLGEAVLDGSISYQRGIGAWGAQPD
TLAAQGGPTARHQLYQGRLALQLPLHIASQTLRWSSELRGQYSPDLLMSSEQFAIGGRGSVRGFNTSTLVGQSGYYLRNE
LSWPLPQLQGLALEPYLGLDAGQIARPAYDAGPDRSLSGWAAGLRLSLGGHLSAELSHERALHQPQGWDRPAITHFSITA
QW

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 60384; Mature: 60384

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVIKAACMGGLLFPAWAAATVPDAVLQQNDQQLRHQQQQLEQRRQELQQRPDVFSPTP
CCEEEEHHHHCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ATSPQTALPASDAQHCFTLSRVSLEGAPAGWLAWLQPLADAGLAGCVDLARINGLTAALT
CCCCCCCCCCCCHHHHEEEEHEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
NEMVARGFVTSRVYLPEQNLRGGQLRLAVVPGRIHAIQLKAGGSDIGLRSAFPAVAGDIL
HHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHC
NVRDLEQGLEQLGRVPGQQATMELTPADAPGESDVVVDRGGGRLLSGLLSLDDSGQNATG
CHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCC
RLQTSGSLTLGGATGLNDALSLSWSQDAEHLAHPLSQSASLSWLLPLGNWTGFFSYSGFA
EEECCCCEEECCCCCCCHHEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCH
YHQTVQGVNQSFTSSGHSRNTLLSLSRLLRRNQSGKTELKLSLTRKASRSFVEDAEVAQQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
RRDLTIAGLELSHRQYLGEAVLDGSISYQRGIGAWGAQPDTLAAQGGPTARHQLYQGRLA
HCCCEEEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEECCCCCHHHHHHHCCCEE
LQLPLHIASQTLRWSSELRGQYSPDLLMSSEQFAIGGRGSVRGFNTSTLVGQSGYYLRNE
EEECHHHHHHHHHHHHHHCCCCCCCCEECCCCEEECCCCCCCCCCCCEEECCCCCEEECC
LSWPLPQLQGLALEPYLGLDAGQIARPAYDAGPDRSLSGWAAGLRLSLGGHLSAELSHER
CCCCCHHHCCEEECCCCCCCCCHHCCCCCCCCCCCCCCHHHCCEEEEECCCCCHHHHHHH
ALHQPQGWDRPAITHFSITAQW
HHCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MNFVIKAACMGGLLFPAWAAATVPDAVLQQNDQQLRHQQQQLEQRRQELQQRPDVFSPTP
CCEEEEHHHHCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ATSPQTALPASDAQHCFTLSRVSLEGAPAGWLAWLQPLADAGLAGCVDLARINGLTAALT
CCCCCCCCCCCCHHHHEEEEHEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHH
NEMVARGFVTSRVYLPEQNLRGGQLRLAVVPGRIHAIQLKAGGSDIGLRSAFPAVAGDIL
HHHHHHHHHHEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHC
NVRDLEQGLEQLGRVPGQQATMELTPADAPGESDVVVDRGGGRLLSGLLSLDDSGQNATG
CHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCC
RLQTSGSLTLGGATGLNDALSLSWSQDAEHLAHPLSQSASLSWLLPLGNWTGFFSYSGFA
EEECCCCEEECCCCCCCHHEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCH
YHQTVQGVNQSFTSSGHSRNTLLSLSRLLRRNQSGKTELKLSLTRKASRSFVEDAEVAQQ
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHH
RRDLTIAGLELSHRQYLGEAVLDGSISYQRGIGAWGAQPDTLAAQGGPTARHQLYQGRLA
HCCCEEEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEECCCCCHHHHHHHCCCEE
LQLPLHIASQTLRWSSELRGQYSPDLLMSSEQFAIGGRGSVRGFNTSTLVGQSGYYLRNE
EEECHHHHHHHHHHHHHHCCCCCCCCEECCCCEEECCCCCCCCCCCCEEECCCCCEEECC
LSWPLPQLQGLALEPYLGLDAGQIARPAYDAGPDRSLSGWAAGLRLSLGGHLSAELSHER
CCCCCHHHCCEEECCCCCCCCCHHCCCCCCCCCCCCCCHHHCCEEEEECCCCCHHHHHHH
ALHQPQGWDRPAITHFSITAQW
HHCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]