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The map label for this gene is silC [H]

Identifier: 34498303

GI number: 34498303

Start: 3103324

End: 3104727

Strand: Direct

Name: silC [H]

Synonym: CV_2848

Alternate gene names: 34498303

Gene position: 3103324-3104727 (Clockwise)

Preceding gene: 34498302

Following gene: 34498304

Centisome position: 65.32

GC content: 74.29

Gene sequence:

>1404_bases
CTGAGCGCGCTGGTCCTGGCCGGCGCGCTGGCCGGCTGCGCCGCCGTCGGTCCGGATTACCATCTGCCATCGCAGGCCGC
GCTGGGCAAGCCCGCCGCCAACGCCGCCTTCCTGTCCGCGAGCGCCCCGGCATTCGCCCAGCAGCCCGTCCCCGCCGGCT
GGTGGCGGCTGTATGACGACGCCAGGCTGGACACGCTGGTGGCAGAAGCGTTGGCCGCCAACGCCGACATCCGCGCCGCC
GCCGCCAATCTGCGCAAGGCGCTGGCGGTGGAGGCATCGGTCAACGCCGAGCGCGACCCGCACGCCAGCGTGTCCGCCGC
CGTCCAGCGCGCGCAAGACTCCGGCGAGGCGTATTTGATCGAGAAAAAGCTGCCGGTGGCCAATGTCGGCGACGGCGGGC
TGAAGATAGGCTACGAGATCGACCTGTTCGGCAAACTGGCCCGCGCCGAGGAAGCCGCCCGCGCCGGCACCCAGGCTTCC
GAAGCCGCGATGGACCTGGCGCGGACCACGGTGGCGGCGGAAACCGTGCGCGCCTATGTGCAAGGCTGCGCGGCCGGACA
CCAGCTGGCGGTGGCCAAACATGAACTCGACCTGCAGAACCGCGGCGTGGCGGTGGCCAAGCGCATGCAGTCCGCCGGGC
GGGGCCGCGCCACCGACGTGGAACGCGCCCAGGCCCAGGCCGACATCCAGCGCGCCGCGCTGCCGCGGCTGCAGGCGGAA
CAGGACGCCGCCCGCTTCCGCCTGGCCGCGCTGCTGGGCAAGACGCCGGCCGAGCTGCCCGCCGCCGCCTGCTCCGACCT
GCCGCGGCTGAAGCGGCCGCTGCCGGTCGGCGACGGCGCGGCGCTGCTCAAGCGCCGCCCTGACGTGCGCGCGGCGGAGC
GCAAGCTCGCCGCCGCCACCGCCCGCATCGGCGTGGCCGCCGCCCAGCTCTATCCCAGCGTCAGCCTGGGCGCGTCGGCC
GGCGTCACCGGCCTGCTGGAGCACGCGGGCGAAGACCGCACCCGGCGCTGGAGCCTGGGACCGCTGATCAGTTGGACCAT
TCCGGACAGCGGCGCGCGCGCCCGGGTGAAGGCGGCCGAAGCCGAAGCCGACGCGGCGCTCGCCCATTTCGACGGCGTGG
TGCTGAACGCGCTGCGCGAAACCGAAACCGCGCTGACCTTCTACGCCAAGGACCTGGAGCGCAACGCCGACCTGCGCTCG
GCGCGCGACAACGCCCGCGCCGCGGCGCAGGACAATCGCCGCCTGTACGCGGCGGGACGCGCGCCCTACCTGGCCAGCCT
GGACGCGGACCGCGCGCTGGCCGGCAACGAATCGGCGCTGGCCGCCTCGGACGCGCAAGTGGCGCTGGACCAGGTCAATC
TGTTCCTGGCGCTGGGCGGCGGCTGGGAGCAGATCCCACGTTGA

Upstream 100 bases:

>100_bases
TCGCGCTGGACGAAGTGCCGGCCAATTTCCGGCTGATCGCCGGCCGCACCGCCACCGTGTCGGTGCGCCAGGGAGGCCGT
TCATGAAAGCCGCGCGCAAG

Downstream 100 bases:

>100_bases
ACCTCGCAATCGAACAGAACGACGATATGAAACAGGAAGTGATTTTTCTCAGCGAAGACCTGGAACTGGTCGGCCATCTC
TACCGCCCCGCCGATTACCA

Product: outer membrane component of multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSALVLAGALAGCAAVGPDYHLPSQAALGKPAANAAFLSASAPAFAQQPVPAGWWRLYDDARLDTLVAEALAANADIRAA
AANLRKALAVEASVNAERDPHASVSAAVQRAQDSGEAYLIEKKLPVANVGDGGLKIGYEIDLFGKLARAEEAARAGTQAS
EAAMDLARTTVAAETVRAYVQGCAAGHQLAVAKHELDLQNRGVAVAKRMQSAGRGRATDVERAQAQADIQRAALPRLQAE
QDAARFRLAALLGKTPAELPAAACSDLPRLKRPLPVGDGAALLKRRPDVRAAERKLAAATARIGVAAAQLYPSVSLGASA
GVTGLLEHAGEDRTRRWSLGPLISWTIPDSGARARVKAAEAEADAALAHFDGVVLNALRETETALTFYAKDLERNADLRS
ARDNARAAAQDNRRLYAAGRAPYLASLDADRALAGNESALAASDAQVALDQVNLFLALGGGWEQIPR

Sequences:

>Translated_467_residues
MSALVLAGALAGCAAVGPDYHLPSQAALGKPAANAAFLSASAPAFAQQPVPAGWWRLYDDARLDTLVAEALAANADIRAA
AANLRKALAVEASVNAERDPHASVSAAVQRAQDSGEAYLIEKKLPVANVGDGGLKIGYEIDLFGKLARAEEAARAGTQAS
EAAMDLARTTVAAETVRAYVQGCAAGHQLAVAKHELDLQNRGVAVAKRMQSAGRGRATDVERAQAQADIQRAALPRLQAE
QDAARFRLAALLGKTPAELPAAACSDLPRLKRPLPVGDGAALLKRRPDVRAAERKLAAATARIGVAAAQLYPSVSLGASA
GVTGLLEHAGEDRTRRWSLGPLISWTIPDSGARARVKAAEAEADAALAHFDGVVLNALRETETALTFYAKDLERNADLRS
ARDNARAAAQDNRRLYAAGRAPYLASLDADRALAGNESALAASDAQVALDQVNLFLALGGGWEQIPR
>Mature_466_residues
SALVLAGALAGCAAVGPDYHLPSQAALGKPAANAAFLSASAPAFAQQPVPAGWWRLYDDARLDTLVAEALAANADIRAAA
ANLRKALAVEASVNAERDPHASVSAAVQRAQDSGEAYLIEKKLPVANVGDGGLKIGYEIDLFGKLARAEEAARAGTQASE
AAMDLARTTVAAETVRAYVQGCAAGHQLAVAKHELDLQNRGVAVAKRMQSAGRGRATDVERAQAQADIQRAALPRLQAEQ
DAARFRLAALLGKTPAELPAAACSDLPRLKRPLPVGDGAALLKRRPDVRAAERKLAAATARIGVAAAQLYPSVSLGASAG
VTGLLEHAGEDRTRRWSLGPLISWTIPDSGARARVKAAEAEADAALAHFDGVVLNALRETETALTFYAKDLERNADLRSA
RDNARAAAQDNRRLYAAGRAPYLASLDADRALAGNESALAASDAQVALDQVNLFLALGGGWEQIPR

Specific function: Component of the sil cation-efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=465, Percent_Identity=26.0215053763441, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI2367348, Length=477, Percent_Identity=23.0607966457023, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48660; Mature: 48529

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALVLAGALAGCAAVGPDYHLPSQAALGKPAANAAFLSASAPAFAQQPVPAGWWRLYDD
CCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCCCCHHCCCCCCHHHHHHCC
ARLDTLVAEALAANADIRAAAANLRKALAVEASVNAERDPHASVSAAVQRAQDSGEAYLI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
EKKLPVANVGDGGLKIGYEIDLFGKLARAEEAARAGTQASEAAMDLARTTVAAETVRAYV
ECCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QGCAAGHQLAVAKHELDLQNRGVAVAKRMQSAGRGRATDVERAQAQADIQRAALPRLQAE
HHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
QDAARFRLAALLGKTPAELPAAACSDLPRLKRPLPVGDGAALLKRRPDVRAAERKLAAAT
HHHHHHHHHHHHCCCCHHCCHHHHHCCHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
ARIGVAAAQLYPSVSLGASAGVTGLLEHAGEDRTRRWSLGPLISWTIPDSGARARVKAAE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCEEEHHH
AEADAALAHFDGVVLNALRETETALTFYAKDLERNADLRSARDNARAAAQDNRRLYAAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECC
APYLASLDADRALAGNESALAASDAQVALDQVNLFLALGGGWEQIPR
CCEEEECCCCHHCCCCCCCEECCHHHHHHHHEEEEEEECCCHHHCCC
>Mature Secondary Structure 
SALVLAGALAGCAAVGPDYHLPSQAALGKPAANAAFLSASAPAFAQQPVPAGWWRLYDD
CHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEECCCCCHHCCCCCCHHHHHHCC
ARLDTLVAEALAANADIRAAAANLRKALAVEASVNAERDPHASVSAAVQRAQDSGEAYLI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
EKKLPVANVGDGGLKIGYEIDLFGKLARAEEAARAGTQASEAAMDLARTTVAAETVRAYV
ECCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
QGCAAGHQLAVAKHELDLQNRGVAVAKRMQSAGRGRATDVERAQAQADIQRAALPRLQAE
HHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
QDAARFRLAALLGKTPAELPAAACSDLPRLKRPLPVGDGAALLKRRPDVRAAERKLAAAT
HHHHHHHHHHHHCCCCHHCCHHHHHCCHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
ARIGVAAAQLYPSVSLGASAGVTGLLEHAGEDRTRRWSLGPLISWTIPDSGARARVKAAE
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCEEEEECCCCCCCCEEEHHH
AEADAALAHFDGVVLNALRETETALTFYAKDLERNADLRSARDNARAAAQDNRRLYAAGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECC
APYLASLDADRALAGNESALAASDAQVALDQVNLFLALGGGWEQIPR
CCEEEECCCCHHCCCCCCCEECCHHHHHHHHEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]