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The map label for this gene is aaeA [H]

Identifier: 34498302

GI number: 34498302

Start: 3102434

End: 3103309

Strand: Direct

Name: aaeA [H]

Synonym: CV_2847

Alternate gene names: 34498302

Gene position: 3102434-3103309 (Clockwise)

Preceding gene: 34498301

Following gene: 34498303

Centisome position: 65.3

GC content: 69.29

Gene sequence:

>876_bases
ATGAACAACCGCATTCGCAAAGCCGGGTCCGTGCTGCTGACCCTGGCCACCGTCGCCGTCGCCATCGTGGTGGTGCGGCA
TATCTGGATCTACTACACCGACGCGCCATGGACCCGCGACGGCCATATCGCCGCCGACGTGGTGCAGGTGGCGCCGGACG
TGTCCGGGCTGATCACCGAAGTGAAAGTCTCGGACAACCAGCTGGTCAAGAAAGGCCAGGTGTTGTTCGTGGTGGACCGC
GCGCATTACGAACTGGCGCTGCGCCAGGCCGAAGCCGCCCTCGCCGCGCAGCGCGCCACGCTGGCCCAAGCCCGCCGCGA
GGCCGCGCGCAACCACTCGCTGACCGACCTGGTAGCCGCCGAGGCCCGCGAGGAAGGCGACGCCAAGGTGCAGTTGGGCG
AGGCCACCCTGGCCGCCGCCGAGGCCGCCGTCGGCCTGGCCCGGCTGAACCTGGAGCGCACCACGATCAAAAGCCCGGTG
GACGGCTATCTGAACGACCGCACCCCGCGCGCCGGCGACTACGCCGCCAGCGGCCGCGCGGTGCTGTCCATCGTCGACTC
CCATTCCTTCCACGTGGACGGCTACTTCGAGGAAACCAAGCTGGGCGGCGTGGAGCTCAACCAGCCGGTGGACATCCGGA
TCATGGGCGAATCGCGCAAGCTGCGCGGCCACGTGCAGAGCATCGCCGCCGGCATCGAAAACCGCGACCGCAGCAACGGC
GCCTCGCTGCTGCCCAACGTCAACCCCACCTTCAACTGGGTGCGGCTGGCGCAGCGCATCCCGGTCCGGATCGCGCTGGA
CGAAGTGCCGGCCAATTTCCGGCTGATCGCCGGCCGCACCGCCACCGTGTCGGTGCGCCAGGGAGGCCGTTCATGA

Upstream 100 bases:

>100_bases
CTGGGCCTGTACCGCGCGGTGTGGCACCGCTCCCTCTTCAATTTCGCGCTTTACCTGATCGTGCTGGGCGCCACGATCGC
GCTGTTTCACAGGTGACATC

Downstream 100 bases:

>100_bases
AAGCCGCGCGCAAGCTGAGCGCGCTGGTCCTGGCCGGCGCGCTGGCCGGCTGCGCCGCCGTCGGTCCGGATTACCATCTG
CCATCGCAGGCCGCGCTGGG

Product: fusaric acid resistance protein FusE II

Products: NA

Alternate protein names: pHBA efflux pump protein A [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNNRIRKAGSVLLTLATVAVAIVVVRHIWIYYTDAPWTRDGHIAADVVQVAPDVSGLITEVKVSDNQLVKKGQVLFVVDR
AHYELALRQAEAALAAQRATLAQARREAARNHSLTDLVAAEAREEGDAKVQLGEATLAAAEAAVGLARLNLERTTIKSPV
DGYLNDRTPRAGDYAASGRAVLSIVDSHSFHVDGYFEETKLGGVELNQPVDIRIMGESRKLRGHVQSIAAGIENRDRSNG
ASLLPNVNPTFNWVRLAQRIPVRIALDEVPANFRLIAGRTATVSVRQGGRS

Sequences:

>Translated_291_residues
MNNRIRKAGSVLLTLATVAVAIVVVRHIWIYYTDAPWTRDGHIAADVVQVAPDVSGLITEVKVSDNQLVKKGQVLFVVDR
AHYELALRQAEAALAAQRATLAQARREAARNHSLTDLVAAEAREEGDAKVQLGEATLAAAEAAVGLARLNLERTTIKSPV
DGYLNDRTPRAGDYAASGRAVLSIVDSHSFHVDGYFEETKLGGVELNQPVDIRIMGESRKLRGHVQSIAAGIENRDRSNG
ASLLPNVNPTFNWVRLAQRIPVRIALDEVPANFRLIAGRTATVSVRQGGRS
>Mature_291_residues
MNNRIRKAGSVLLTLATVAVAIVVVRHIWIYYTDAPWTRDGHIAADVVQVAPDVSGLITEVKVSDNQLVKKGQVLFVVDR
AHYELALRQAEAALAAQRATLAQARREAARNHSLTDLVAAEAREEGDAKVQLGEATLAAAEAAVGLARLNLERTTIKSPV
DGYLNDRTPRAGDYAASGRAVLSIVDSHSFHVDGYFEETKLGGVELNQPVDIRIMGESRKLRGHVQSIAAGIENRDRSNG
ASLLPNVNPTFNWVRLAQRIPVRIALDEVPANFRLIAGRTATVSVRQGGRS

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081951, Length=277, Percent_Identity=40.7942238267148, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1789637, Length=288, Percent_Identity=42.0138888888889, Blast_Score=217, Evalue=6e-58,
Organism=Escherichia coli, GI1790519, Length=312, Percent_Identity=32.0512820512821, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789041, Length=304, Percent_Identity=27.3026315789474, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788711, Length=306, Percent_Identity=27.7777777777778, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI87082036, Length=155, Percent_Identity=34.1935483870968, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022871
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 31532; Mature: 31532

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRIRKAGSVLLTLATVAVAIVVVRHIWIYYTDAPWTRDGHIAADVVQVAPDVSGLITE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCCHHEEE
VKVSDNQLVKKGQVLFVVDRAHYELALRQAEAALAAQRATLAQARREAARNHSLTDLVAA
EEECCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
EAREEGDAKVQLGEATLAAAEAAVGLARLNLERTTIKSPVDGYLNDRTPRAGDYAASGRA
HHHCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
VLSIVDSHSFHVDGYFEETKLGGVELNQPVDIRIMGESRKLRGHVQSIAAGIENRDRSNG
EEEEECCCCEEECCEEECCCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
ASLLPNVNPTFNWVRLAQRIPVRIALDEVPANFRLIAGRTATVSVRQGGRS
CCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MNNRIRKAGSVLLTLATVAVAIVVVRHIWIYYTDAPWTRDGHIAADVVQVAPDVSGLITE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHCCCCCHHEEE
VKVSDNQLVKKGQVLFVVDRAHYELALRQAEAALAAQRATLAQARREAARNHSLTDLVAA
EEECCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
EAREEGDAKVQLGEATLAAAEAAVGLARLNLERTTIKSPVDGYLNDRTPRAGDYAASGRA
HHHCCCCCEEEECHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCE
VLSIVDSHSFHVDGYFEETKLGGVELNQPVDIRIMGESRKLRGHVQSIAAGIENRDRSNG
EEEEECCCCEEECCEEECCCCCCEECCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCC
ASLLPNVNPTFNWVRLAQRIPVRIALDEVPANFRLIAGRTATVSVRQGGRS
CCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA