Click here to switch to the map view.

The map label for this gene is yheS [H]

Identifier: 34498213

GI number: 34498213

Start: 2993487

End: 2995391

Strand: Direct

Name: yheS [H]

Synonym: CV_2758

Alternate gene names: 34498213

Gene position: 2993487-2995391 (Clockwise)

Preceding gene: 34498212

Following gene: 34498214

Centisome position: 63.01

GC content: 66.4

Gene sequence:

>1905_bases
ATGATCCAACTGAAAAATCTGAGCCTGCGCCGCGGCCTGAAGGAATTGCTGATCGGCGCCAACCTGACGCTGAATCCCGG
CTACAAGGCCGGCCTGACCGGCGCCAACGGCGTCGGCAAGTCCAGCCTGTTCGCCATGCTGCTGGGCGAGTTGCACGCCG
ACGGCGGCGACATGCTGCTGCCGCCCAACTGGACCGTCGCCCACGTGGCGCAGGAAACGCCGGCGCTGGAACGCAGCGCG
CTCGACTACGTGCTGGACGGCGACAAGGAGCTGCGCGCGCTGGAGTCGCAGCTGGCCGACGCGGAAGACAAGCATGACGG
CAACGCCATCGGCCATCTGCACGGCGAGCTGGCCAATATCGACGCCTACTCCGCCCCGGCGCGCGCCGGCAAGCTGTTGA
CCGGCCTGGGCTTCGACGAGGCCGCCCAGCAGCGCCCGGTGGCCAGCTTCTCCGGCGGCTGGCGCATGCGCCTGAACCTG
GCCCAGGCGCTGATGTGCCGCTCCGACCTGCTGCTGCTGGACGAGCCGACCAACCACCTGGACCTGGAAACGGTGCTGTG
GCTGGAGGACTGGCTGAAGGCCTATCCCGGCACCCTGCTGGTGATCTCGCACGACCGCGATTTCCTGGACGCCATCTGCA
GCCACATCGTCGAAGTGGCCAGCCAGACGCTGACGCTGTACACCGGCAACTACAGCCAGTTCGAAGTCATGCGCGCCGAG
AAGCTGGCGCGCCAGCAAGGCGAATACGAAAAGCAGCAGCGCCAGATCGCCCACCTGGAATCGTTCATCAACCGCTTCAA
GGCCAAGGCCAGCAAGGCGCGCCAGGCGCAGAGCCGGGTCAAGGCGCTGGAGAAGCTGGAACGGATCGCGCCGGCCCACA
TCGCTTCGCCGTTCGACTTCCATTTCGACAGCCCCGAGCACCTGCCCAATCCCTTGCTGAAGCTGGACAAGGCCGACGCC
GGCTACGGCGACAAGACCATCCTGTCCGGCATCAGCCTGTCGGTGGAAGCCGGCGCGCGCATCGGCCTGTTGGGCGTCAA
CGGCGCCGGCAAGTCGACGCTGGTCAAGCTGCTGTCCGGCGACCTCGCGCCGCAAGCCGGCGAGCGCATCAACGCGCAGA
TGCTGAAGATAGGCTATTTCGCCCAGCACACGCTGGAGACGCTGCGCCCGGATGAAAGCCCCCTGCAGCACATGCAGCGC
CTGGCGCCGACCACGCGCGAACTGGAGCTCAGGAGTTTCCTCGGCGGCTTCAACTTCCGCGGCGACGCCGCCACCGACCC
GGTCGGCCCGATGTCCGGCGGCGAGAAGGCCCGCCTCGCGCTGGCCATGATCGTGTGGCAGAAACCCAACCTGCTGCTGC
TGGACGAACCGACCAACCACCTGGACCTGGAAATGCGCCACGCGCTGACGCTGGCGCTGCAGGACTTCACCGGCGCGCTG
ATCGTGGTCTCCCACGACCGCAGCCTGCTGGAGTCCACCACCGACGTGTTCTGGCTGGTCAGCGGCGGCAAGGTGCAGCC
CTTCGACGGCGACCTGGAAGACTACCGCCAATGGCGCATCGCCCAACTGGCGGAAGGCGGCAAACCGTCCGACGGCGACG
CCCAGGGCGTCAACCGCAAGGAACAGAAGCGCCAGGAGGCAGAGGCTCGCCAGCAATTGGCCAAGCAACGCAAGCCCTTG
CAAACCCGCCTGTCCAAGCTGGAGCAGGAAATGAACAAGCTGAGCGACGAGAAAGCCGAGCTGGAAGCCTTCATGTCCTC
CAGCGAGGCCTACGACGATGCCAACCGCCAGAAGCTGGCCGACAGCGTGAAACGCCAGGGCGAAGTCGCCAGCCGGCTGG
AAATCGTCGAAGAGGAATGGATGGAAGTGCAGGAGCAGCTGGAAGCGCTGGCTCAGGCCGACTGA

Upstream 100 bases:

>100_bases
GGCGGCTTCACCATCAAGCCGCGCTGGGATTTGTCCAGCCTGCCGGCAGTATAAACGCATCCATGCCGCCGGTCCCGGGC
CGCGCGGCCAGAAAATCAAT

Downstream 100 bases:

>100_bases
GCGCCGCATGCGATGGGTGATGGCGGAGAGAGAAATGGCTTGCAATCTCCGCCGCCATCTTCTTACGCTAAAGAAGAAGA
CGGGCCCGCCCGCCAACCGG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MIQLKNLSLRRGLKELLIGANLTLNPGYKAGLTGANGVGKSSLFAMLLGELHADGGDMLLPPNWTVAHVAQETPALERSA
LDYVLDGDKELRALESQLADAEDKHDGNAIGHLHGELANIDAYSAPARAGKLLTGLGFDEAAQQRPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLETVLWLEDWLKAYPGTLLVISHDRDFLDAICSHIVEVASQTLTLYTGNYSQFEVMRAE
KLARQQGEYEKQQRQIAHLESFINRFKAKASKARQAQSRVKALEKLERIAPAHIASPFDFHFDSPEHLPNPLLKLDKADA
GYGDKTILSGISLSVEAGARIGLLGVNGAGKSTLVKLLSGDLAPQAGERINAQMLKIGYFAQHTLETLRPDESPLQHMQR
LAPTTRELELRSFLGGFNFRGDAATDPVGPMSGGEKARLALAMIVWQKPNLLLLDEPTNHLDLEMRHALTLALQDFTGAL
IVVSHDRSLLESTTDVFWLVSGGKVQPFDGDLEDYRQWRIAQLAEGGKPSDGDAQGVNRKEQKRQEAEARQQLAKQRKPL
QTRLSKLEQEMNKLSDEKAELEAFMSSSEAYDDANRQKLADSVKRQGEVASRLEIVEEEWMEVQEQLEALAQAD

Sequences:

>Translated_634_residues
MIQLKNLSLRRGLKELLIGANLTLNPGYKAGLTGANGVGKSSLFAMLLGELHADGGDMLLPPNWTVAHVAQETPALERSA
LDYVLDGDKELRALESQLADAEDKHDGNAIGHLHGELANIDAYSAPARAGKLLTGLGFDEAAQQRPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLETVLWLEDWLKAYPGTLLVISHDRDFLDAICSHIVEVASQTLTLYTGNYSQFEVMRAE
KLARQQGEYEKQQRQIAHLESFINRFKAKASKARQAQSRVKALEKLERIAPAHIASPFDFHFDSPEHLPNPLLKLDKADA
GYGDKTILSGISLSVEAGARIGLLGVNGAGKSTLVKLLSGDLAPQAGERINAQMLKIGYFAQHTLETLRPDESPLQHMQR
LAPTTRELELRSFLGGFNFRGDAATDPVGPMSGGEKARLALAMIVWQKPNLLLLDEPTNHLDLEMRHALTLALQDFTGAL
IVVSHDRSLLESTTDVFWLVSGGKVQPFDGDLEDYRQWRIAQLAEGGKPSDGDAQGVNRKEQKRQEAEARQQLAKQRKPL
QTRLSKLEQEMNKLSDEKAELEAFMSSSEAYDDANRQKLADSVKRQGEVASRLEIVEEEWMEVQEQLEALAQAD
>Mature_634_residues
MIQLKNLSLRRGLKELLIGANLTLNPGYKAGLTGANGVGKSSLFAMLLGELHADGGDMLLPPNWTVAHVAQETPALERSA
LDYVLDGDKELRALESQLADAEDKHDGNAIGHLHGELANIDAYSAPARAGKLLTGLGFDEAAQQRPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLETVLWLEDWLKAYPGTLLVISHDRDFLDAICSHIVEVASQTLTLYTGNYSQFEVMRAE
KLARQQGEYEKQQRQIAHLESFINRFKAKASKARQAQSRVKALEKLERIAPAHIASPFDFHFDSPEHLPNPLLKLDKADA
GYGDKTILSGISLSVEAGARIGLLGVNGAGKSTLVKLLSGDLAPQAGERINAQMLKIGYFAQHTLETLRPDESPLQHMQR
LAPTTRELELRSFLGGFNFRGDAATDPVGPMSGGEKARLALAMIVWQKPNLLLLDEPTNHLDLEMRHALTLALQDFTGAL
IVVSHDRSLLESTTDVFWLVSGGKVQPFDGDLEDYRQWRIAQLAEGGKPSDGDAQGVNRKEQKRQEAEARQQLAKQRKPL
QTRLSKLEQEMNKLSDEKAELEAFMSSSEAYDDANRQKLADSVKRQGEVASRLEIVEEEWMEVQEQLEALAQAD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=525, Percent_Identity=41.1428571428571, Blast_Score=388, Evalue=1e-107,
Organism=Homo sapiens, GI10947137, Length=535, Percent_Identity=35.8878504672897, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI27881506, Length=535, Percent_Identity=35.8878504672897, Blast_Score=331, Evalue=2e-90,
Organism=Homo sapiens, GI10947135, Length=542, Percent_Identity=36.90036900369, Blast_Score=289, Evalue=6e-78,
Organism=Homo sapiens, GI69354671, Length=542, Percent_Identity=36.90036900369, Blast_Score=288, Evalue=9e-78,
Organism=Homo sapiens, GI42741659, Length=258, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI27881501, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI30795238, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI148612844, Length=207, Percent_Identity=29.951690821256, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1789751, Length=636, Percent_Identity=57.5471698113208, Blast_Score=732, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=36.2595419847328, Blast_Score=328, Evalue=9e-91,
Organism=Escherichia coli, GI1787182, Length=637, Percent_Identity=30.298273155416, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI2367384, Length=525, Percent_Identity=30.0952380952381, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1788165, Length=189, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081782, Length=524, Percent_Identity=25, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787758, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787029, Length=215, Percent_Identity=24.1860465116279, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=536, Percent_Identity=39.5522388059701, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=37.1916508538899, Blast_Score=343, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17559834, Length=555, Percent_Identity=33.5135135135135, Blast_Score=311, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=36.1510791366906, Blast_Score=346, Evalue=7e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=33.2699619771863, Blast_Score=303, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=31.7708333333333, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324314, Length=411, Percent_Identity=27.9805352798054, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=409, Percent_Identity=27.1393643031785, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=39.6584440227704, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24642252, Length=528, Percent_Identity=38.8257575757576, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI18859989, Length=528, Percent_Identity=38.8257575757576, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24641342, Length=546, Percent_Identity=34.7985347985348, Blast_Score=328, Evalue=7e-90,
Organism=Drosophila melanogaster, GI221500365, Length=156, Percent_Identity=32.6923076923077, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007184, Length=156, Percent_Identity=32.6923076923077, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70047; Mature: 70047

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLKNLSLRRGLKELLIGANLTLNPGYKAGLTGANGVGKSSLFAMLLGELHADGGDMLL
CCEECCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
PPNWTVAHVAQETPALERSALDYVLDGDKELRALESQLADAEDKHDGNAIGHLHGELANI
CCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEHHHCCHHHCC
DAYSAPARAGKLLTGLGFDEAAQQRPVASFSGGWRMRLNLAQALMCRSDLLLLDEPTNHL
CCCCCCHHHCHHHHCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLETVLWLEDWLKAYPGTLLVISHDRDFLDAICSHIVEVASQTLTLYTGNYSQFEVMRAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHH
KLARQQGEYEKQQRQIAHLESFINRFKAKASKARQAQSRVKALEKLERIAPAHIASPFDF
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCC
HFDSPEHLPNPLLKLDKADAGYGDKTILSGISLSVEAGARIGLLGVNGAGKSTLVKLLSG
CCCCHHHCCCHHHCCCCCCCCCCCHHHHHCCCEEEECCCEEEEEEECCCCHHHHHHHHHC
DLAPQAGERINAQMLKIGYFAQHTLETLRPDESPLQHMQRLAPTTRELELRSFLGGFNFR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
GDAATDPVGPMSGGEKARLALAMIVWQKPNLLLLDEPTNHLDLEMRHALTLALQDFTGAL
CCCCCCCCCCCCCCCHHHHHEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
IVVSHDRSLLESTTDVFWLVSGGKVQPFDGDLEDYRQWRIAQLAEGGKPSDGDAQGVNRK
EEEECCHHHHHCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EQKRQEAEARQQLAKQRKPLQTRLSKLEQEMNKLSDEKAELEAFMSSSEAYDDANRQKLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHH
DSVKRQGEVASRLEIVEEEWMEVQEQLEALAQAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIQLKNLSLRRGLKELLIGANLTLNPGYKAGLTGANGVGKSSLFAMLLGELHADGGDMLL
CCEECCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEE
PPNWTVAHVAQETPALERSALDYVLDGDKELRALESQLADAEDKHDGNAIGHLHGELANI
CCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEHHHCCHHHCC
DAYSAPARAGKLLTGLGFDEAAQQRPVASFSGGWRMRLNLAQALMCRSDLLLLDEPTNHL
CCCCCCHHHCHHHHCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLETVLWLEDWLKAYPGTLLVISHDRDFLDAICSHIVEVASQTLTLYTGNYSQFEVMRAE
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHH
KLARQQGEYEKQQRQIAHLESFINRFKAKASKARQAQSRVKALEKLERIAPAHIASPFDF
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCC
HFDSPEHLPNPLLKLDKADAGYGDKTILSGISLSVEAGARIGLLGVNGAGKSTLVKLLSG
CCCCHHHCCCHHHCCCCCCCCCCCHHHHHCCCEEEECCCEEEEEEECCCCHHHHHHHHHC
DLAPQAGERINAQMLKIGYFAQHTLETLRPDESPLQHMQRLAPTTRELELRSFLGGFNFR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
GDAATDPVGPMSGGEKARLALAMIVWQKPNLLLLDEPTNHLDLEMRHALTLALQDFTGAL
CCCCCCCCCCCCCCCHHHHHEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
IVVSHDRSLLESTTDVFWLVSGGKVQPFDGDLEDYRQWRIAQLAEGGKPSDGDAQGVNRK
EEEECCHHHHHCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
EQKRQEAEARQQLAKQRKPLQTRLSKLEQEMNKLSDEKAELEAFMSSSEAYDDANRQKLA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHH
DSVKRQGEVASRLEIVEEEWMEVQEQLEALAQAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]