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The map label for this gene is mdtA [H]

Identifier: 34498187

GI number: 34498187

Start: 2963445

End: 2964683

Strand: Direct

Name: mdtA [H]

Synonym: CV_2732

Alternate gene names: 34498187

Gene position: 2963445-2964683 (Clockwise)

Preceding gene: 34498173

Following gene: 34498188

Centisome position: 62.37

GC content: 67.23

Gene sequence:

>1239_bases
ATGTCGACCGCCGCGCCAGTCAAATCCAAACGCCTGCCCTTGATACTCATCCTGCTTGCCGCGCTGGGCGGCGGCTGGTG
GTGGCACCAGCATAGCCAGAGTGCCAAGGAAGCCGCGGCCAGGAACAAGGGCGCCGCGCCGATGGCGGTGGGCGTGGCGG
CCGTGCAGGCCATGGACGCGCCGCTGCAGCTGAACGCGCTGGGCACCGTCACCTCCGCCTATACCGTGACCGTGCGCAGC
CGCGTCGACGGACAATTGGAAAAGGTTCATTTCACCGAAGGCCAACAGGTCAAGCAAGGCCAGTTGCTGGCTGAGCTGGA
CGCCCGCTCCTACCAGGCCGCGCTGACTCAGGCCGAAGGCCAGCTGCTGCGCGACCAGGCGCTGCTGGAGAACGCCAGGC
TGGACCTGGCCCGCTACCAGCAGCTGGCCAGCCAGAACTCCATCGCCAAGCAACAGGTCGACACCCAGCAGGCGCTGGTG
CGCCAGTACCAGGGCACGGTCAAGGTCGACCAGGGCGCCGTCGCAGCCGCCCGCGTCAACGTCGACTACACCCGCGTCAC
GGCGCCGATCTCCGGCCGCGTCGGCCTGCGCCAGGTGGACCCGGGCAACATCGTCCATGCCAGCGACGCCAACGGCCTGG
TCACCATCACCCAGACGCAGCCGATCAACGTCACCTTCGCGATCCCCGAGGTCAGCCTGAGCCCGGTGCTGCAGGCCGCG
CGCGACAACAAGACGCTCAAGGTGGAAGCCTGGGACCGCGACAACCGCCACAAACTGGCCGACGGCAAGCTGCTGGCGCT
GGACAACCAGTTGAACACCAGCACCGGCACCATCAATATCAAGGCGACATTCGCCAATGAGCAGCAGCAGCTGTTCCCCA
ACCAGTTCGTCAACGTCAACCTGCAGCTGGGCGTGCGCAAGGACGCGGTGGTAGTCCCCACCGCCGCGGTGCAGCTGGGC
AAGATGGGCAACTACGTCTACACCGTCGGCGCAGATTCCATGGTCAGCATCGCCAAGGTCAAGACCGGCCCGGTGTCCGG
CGGCAACACCATCATCGAGGAAGGCTTGCGACCGGGCCAGCAGGTGGTGATAGACGGCGTGGACAAGCTGCGCGACGGCG
CCAAGGTCAAAGTGATAGACCGCGCCGCCCAGGCGCGCGAAGCCGCCTCGGCCGCCGCAGGCGAAGCCAAGGGGCACAAG
CCGCGCGGCGGCAAGCAGCACGCCTCGGCGGCCCATTAA

Upstream 100 bases:

>100_bases
CAGCACTAAATCGCTGTTTTTCCGCATCGCCGCAGCACAAAGCATGTAAAAATGTCATGCTTTGCCACACAACAACAACC
AGCAGCCCGGAGCTCTCCGC

Downstream 100 bases:

>100_bases
GCGGAAGGACACAGCATGAATCCCTCCCGTCCGTTCATTATGCGGCCGGTGGCCACCACCTTGCTGATGGTGGCCATCCT
GCTGACCGGCCTGGTGGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSTAAPVKSKRLPLILILLAALGGGWWWHQHSQSAKEAAARNKGAAPMAVGVAAVQAMDAPLQLNALGTVTSAYTVTVRS
RVDGQLEKVHFTEGQQVKQGQLLAELDARSYQAALTQAEGQLLRDQALLENARLDLARYQQLASQNSIAKQQVDTQQALV
RQYQGTVKVDQGAVAAARVNVDYTRVTAPISGRVGLRQVDPGNIVHASDANGLVTITQTQPINVTFAIPEVSLSPVLQAA
RDNKTLKVEAWDRDNRHKLADGKLLALDNQLNTSTGTINIKATFANEQQQLFPNQFVNVNLQLGVRKDAVVVPTAAVQLG
KMGNYVYTVGADSMVSIAKVKTGPVSGGNTIIEEGLRPGQQVVIDGVDKLRDGAKVKVIDRAAQAREAASAAAGEAKGHK
PRGGKQHASAAH

Sequences:

>Translated_412_residues
MSTAAPVKSKRLPLILILLAALGGGWWWHQHSQSAKEAAARNKGAAPMAVGVAAVQAMDAPLQLNALGTVTSAYTVTVRS
RVDGQLEKVHFTEGQQVKQGQLLAELDARSYQAALTQAEGQLLRDQALLENARLDLARYQQLASQNSIAKQQVDTQQALV
RQYQGTVKVDQGAVAAARVNVDYTRVTAPISGRVGLRQVDPGNIVHASDANGLVTITQTQPINVTFAIPEVSLSPVLQAA
RDNKTLKVEAWDRDNRHKLADGKLLALDNQLNTSTGTINIKATFANEQQQLFPNQFVNVNLQLGVRKDAVVVPTAAVQLG
KMGNYVYTVGADSMVSIAKVKTGPVSGGNTIIEEGLRPGQQVVIDGVDKLRDGAKVKVIDRAAQAREAASAAAGEAKGHK
PRGGKQHASAAH
>Mature_411_residues
STAAPVKSKRLPLILILLAALGGGWWWHQHSQSAKEAAARNKGAAPMAVGVAAVQAMDAPLQLNALGTVTSAYTVTVRSR
VDGQLEKVHFTEGQQVKQGQLLAELDARSYQAALTQAEGQLLRDQALLENARLDLARYQQLASQNSIAKQQVDTQQALVR
QYQGTVKVDQGAVAAARVNVDYTRVTAPISGRVGLRQVDPGNIVHASDANGLVTITQTQPINVTFAIPEVSLSPVLQAAR
DNKTLKVEAWDRDNRHKLADGKLLALDNQLNTSTGTINIKATFANEQQQLFPNQFVNVNLQLGVRKDAVVVPTAAVQLGK
MGNYVYTVGADSMVSIAKVKTGPVSGGNTIIEEGLRPGQQVVIDGVDKLRDGAKVKVIDRAAQAREAASAAAGEAKGHKP
RGGKQHASAAH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=386, Percent_Identity=47.4093264248705, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1786668, Length=354, Percent_Identity=33.6158192090396, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789665, Length=378, Percent_Identity=31.7460317460317, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789929, Length=392, Percent_Identity=26.530612244898, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081796, Length=143, Percent_Identity=30.0699300699301, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43830; Mature: 43699

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAAPVKSKRLPLILILLAALGGGWWWHQHSQSAKEAAARNKGAAPMAVGVAAVQAMDA
CCCCCCCCCCCCCHHHHHHHHHCCCEEEHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
PLQLNALGTVTSAYTVTVRSRVDGQLEKVHFTEGQQVKQGQLLAELDARSYQAALTQAEG
CEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QLLRDQALLENARLDLARYQQLASQNSIAKQQVDTQQALVRQYQGTVKVDQGAVAAARVN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEE
VDYTRVTAPISGRVGLRQVDPGNIVHASDANGLVTITQTQPINVTFAIPEVSLSPVLQAA
CEEEEEECCCCCCCCCEECCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCHHHHHHHH
RDNKTLKVEAWDRDNRHKLADGKLLALDNQLNTSTGTINIKATFANEQQQLFPNQFVNVN
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCHHHHCCCCEEEEE
LQLGVRKDAVVVPTAAVQLGKMGNYVYTVGADSMVSIAKVKTGPVSGGNTIIEEGLRPGQ
EEECCCCCEEEECHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCCCC
QVVIDGVDKLRDGAKVKVIDRAAQAREAASAAAGEAKGHKPRGGKQHASAAH
EEEEECHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STAAPVKSKRLPLILILLAALGGGWWWHQHSQSAKEAAARNKGAAPMAVGVAAVQAMDA
CCCCCCCCCCCCHHHHHHHHHCCCEEEHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHCC
PLQLNALGTVTSAYTVTVRSRVDGQLEKVHFTEGQQVKQGQLLAELDARSYQAALTQAEG
CEEEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QLLRDQALLENARLDLARYQQLASQNSIAKQQVDTQQALVRQYQGTVKVDQGAVAAARVN
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEE
VDYTRVTAPISGRVGLRQVDPGNIVHASDANGLVTITQTQPINVTFAIPEVSLSPVLQAA
CEEEEEECCCCCCCCCEECCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCHHHHHHHH
RDNKTLKVEAWDRDNRHKLADGKLLALDNQLNTSTGTINIKATFANEQQQLFPNQFVNVN
CCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECCCHHHHCCCCEEEEE
LQLGVRKDAVVVPTAAVQLGKMGNYVYTVGADSMVSIAKVKTGPVSGGNTIIEEGLRPGQ
EEECCCCCEEEECHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHCCCCCC
QVVIDGVDKLRDGAKVKVIDRAAQAREAASAAAGEAKGHKPRGGKQHASAAH
EEEEECHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA