Click here to switch to the map view.

The map label for this gene is dsdC [H]

Identifier: 34498104

GI number: 34498104

Start: 2862619

End: 2863536

Strand: Direct

Name: dsdC [H]

Synonym: CV_2649

Alternate gene names: 34498104

Gene position: 2862619-2863536 (Clockwise)

Preceding gene: 34498103

Following gene: 34498106

Centisome position: 60.25

GC content: 71.46

Gene sequence:

>918_bases
ATGCGCTCCGCACGGCTGGATGGCGGCCAGTTTGCCAATCTCCACACTTTCCTGGCGGTCGCCCGCCGGCTGAGCTTCGC
CGCCGCCGCCGACGAGTTGTGCCTGACGCCCAGCGCGGTCAGCCACCGCATCGCCAGGCTGGAACGCTCGCTGGACCTGC
GCCTGTTTCAACGGCTGACACGCGGCATACGCCTTACGCCGGACGGAGAACGCATCCTCGCCGCGCTGGAAAAAAGCATG
GCCGAGCTCGACGCCGCCCTCCATCCCCAAGCCGGCGCGGAACCCGCGGGCCGCGTCGCGCTCTACACGCATCCGTCCAT
CGCGCAGTGCTGGCTGGCGCCGCGGCTGGCCACCCTTGTCGAGCGCCACCCCATGCTCGAACTCGACATCCGCTCCGGCA
ACGGCGACGCCGACTTCCGCGGCGGCGGCGCCGATCTGGCGCTGTACTATGGCGATGGCCGCTTTCCGGGCCTGGCCTCC
CTCAAGCTGATGGACGAGGAAATGGCCCCGGTCTGCAGTCGCGCCTATGCGGAGCGGCACGGGCTGCTGTCCGATCCGGC
CCGGCTGCGCGACTGCCGCCTGCTGCATGACGCCCAGGCGTGGCGCCACGCCGCCCATGATGCGGAGTGGGCGCTCTGGG
CAAGCCGCCATGGCGTCGAATCCCTGCTGCCGCCGCGCGCGCTGACGCTGGACCGCTCCGACCTGTGCCTGGCGGCGGCG
GCCGGCCATGCCGGCATCGCCATCGGCCGCCGCCGTCTCGCCCAGGCGATGCTGGACAGCGGCCAACTGGTGCTGCCGCT
GGGCGGCTTCGAGGCGGTGGAGCGCTACGCCTACTACCTGGTCCACCCGCGGCAAACCGACTTGTCGGGGCGGTTGCGCG
CCGTGATCGACTGGCTTGTCCAGTCGGCAGCCTGCTGA

Upstream 100 bases:

>100_bases
GCGCCACCCATCTGATCTGGGCGACCGGCGGCAGCATGGTGCCGGAAGCGGAGATGGACGGCTACCTGCGGCGCGGCCGC
GCGCTGCTGGGCTGAGGCCG

Downstream 100 bases:

>100_bases
TCCGCCTCTGGCATTGCGCGCCGCGCCATTGCCAAGGCCAGGCGACGGCACCCGCGCAAAAGTCAATCGATGCGGGAGCA
TGTCTGCGCCCCCATTGCCG

Product: DNA-binding transcriptional regulator DsdC

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRSARLDGGQFANLHTFLAVARRLSFAAAADELCLTPSAVSHRIARLERSLDLRLFQRLTRGIRLTPDGERILAALEKSM
AELDAALHPQAGAEPAGRVALYTHPSIAQCWLAPRLATLVERHPMLELDIRSGNGDADFRGGGADLALYYGDGRFPGLAS
LKLMDEEMAPVCSRAYAERHGLLSDPARLRDCRLLHDAQAWRHAAHDAEWALWASRHGVESLLPPRALTLDRSDLCLAAA
AGHAGIAIGRRRLAQAMLDSGQLVLPLGGFEAVERYAYYLVHPRQTDLSGRLRAVIDWLVQSAAC

Sequences:

>Translated_305_residues
MRSARLDGGQFANLHTFLAVARRLSFAAAADELCLTPSAVSHRIARLERSLDLRLFQRLTRGIRLTPDGERILAALEKSM
AELDAALHPQAGAEPAGRVALYTHPSIAQCWLAPRLATLVERHPMLELDIRSGNGDADFRGGGADLALYYGDGRFPGLAS
LKLMDEEMAPVCSRAYAERHGLLSDPARLRDCRLLHDAQAWRHAAHDAEWALWASRHGVESLLPPRALTLDRSDLCLAAA
AGHAGIAIGRRRLAQAMLDSGQLVLPLGGFEAVERYAYYLVHPRQTDLSGRLRAVIDWLVQSAAC
>Mature_305_residues
MRSARLDGGQFANLHTFLAVARRLSFAAAADELCLTPSAVSHRIARLERSLDLRLFQRLTRGIRLTPDGERILAALEKSM
AELDAALHPQAGAEPAGRVALYTHPSIAQCWLAPRLATLVERHPMLELDIRSGNGDADFRGGGADLALYYGDGRFPGLAS
LKLMDEEMAPVCSRAYAERHGLLSDPARLRDCRLLHDAQAWRHAAHDAEWALWASRHGVESLLPPRALTLDRSDLCLAAA
AGHAGIAIGRRRLAQAMLDSGQLVLPLGGFEAVERYAYYLVHPRQTDLSGRLRAVIDWLVQSAAC

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=41.9141914191419, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1786448, Length=293, Percent_Identity=33.7883959044369, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789173, Length=292, Percent_Identity=31.8493150684932, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=29.6928327645051, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787128, Length=306, Percent_Identity=26.1437908496732, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081978, Length=171, Percent_Identity=30.9941520467836, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=25.938566552901, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787589, Length=185, Percent_Identity=27.5675675675676, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=165, Percent_Identity=32.1212121212121, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=276, Percent_Identity=28.6231884057971, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994962, Length=121, Percent_Identity=36.3636363636364, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33374; Mature: 33374

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSARLDGGQFANLHTFLAVARRLSFAAAADELCLTPSAVSHRIARLERSLDLRLFQRLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGIRLTPDGERILAALEKSMAELDAALHPQAGAEPAGRVALYTHPSIAQCWLAPRLATLV
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
ERHPMLELDIRSGNGDADFRGGGADLALYYGDGRFPGLASLKLMDEEMAPVCSRAYAERH
HHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLLSDPARLRDCRLLHDAQAWRHAAHDAEWALWASRHGVESLLPPRALTLDRSDLCLAAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCEEEECCCCCEEEEC
AGHAGIAIGRRRLAQAMLDSGQLVLPLGGFEAVERYAYYLVHPRQTDLSGRLRAVIDWLV
CCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
QSAAC
HHCCC
>Mature Secondary Structure
MRSARLDGGQFANLHTFLAVARRLSFAAAADELCLTPSAVSHRIARLERSLDLRLFQRLT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RGIRLTPDGERILAALEKSMAELDAALHPQAGAEPAGRVALYTHPSIAQCWLAPRLATLV
CCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHH
ERHPMLELDIRSGNGDADFRGGGADLALYYGDGRFPGLASLKLMDEEMAPVCSRAYAERH
HHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GLLSDPARLRDCRLLHDAQAWRHAAHDAEWALWASRHGVESLLPPRALTLDRSDLCLAAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHCCCCEEEECCCCCEEEEC
AGHAGIAIGRRRLAQAMLDSGQLVLPLGGFEAVERYAYYLVHPRQTDLSGRLRAVIDWLV
CCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHH
QSAAC
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]