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The map label for this gene is dsdA

Identifier: 34498103

GI number: 34498103

Start: 2861267

End: 2862613

Strand: Direct

Name: dsdA

Synonym: CV_2648

Alternate gene names: 34498103

Gene position: 2861267-2862613 (Clockwise)

Preceding gene: 34498102

Following gene: 34498104

Centisome position: 60.22

GC content: 68.52

Gene sequence:

>1347_bases
ATGATTCATGGAAAAACGCTGGCTGAATGGCAGCAGTCCCATCCCGAGATTCGCGAATTGACCGGCCTGCGCGAGTGCGC
CTGGTTCAATCCCGCCGCCGCCCCCGCCGCCGAGGCATTGCCCGATGTCGGACTTGGCGCGGCAGACATCGCCGACGCAT
CCGCCCGCCTGCGGCGTTTCGCGCCATACATATCCCGCGCATTCCCCGAAACCGCCGCCAGCGGCGGGATCATAGAATCG
CCGCTGCTGCCCGTACCCGCCTTCCAGCAAGCGCTGGCCCGCCGCCGCGGACGCGAGTTGCCGGGACGCCTTTGGCTGAA
GGCGGACAGCCACTTGCCCATCTCGGGCTCGATCAAAGCACGCGGCGGCATCTACGAGGTGCTGAAGCATGCGGAAGACC
TGGCGCTGGCCAACGGCCTGCTCCAGCCCGGCGACGACTACGCCAGGCTGGCCTCCCCGGAAGCCCGCTCGCTGTTCAGC
CGCCATGGCATCGCCGTCGGCTCCACCGGCAATCTGGGCCTGTCGATAGGCATCATGGCGGCCAAGCTGGGCTTCCAGGC
CGCCGTCCACATGTCGGCCGACGCCAGGCAATGGAAAAAGGACAAGTTGCGCGCGCACGGCGTAACCGTGGTCGAATACC
AGACCGACTACAGCGCGGCGGTGGCGCGGGGACGGGAACAGGCGGCGCGCGACCCGGATTGCCATTTCGTCGACGACGAA
AATTCCATCCACCTGTTCTTGGGCTACGCCGTGGCGGCGGAACGGCTGAAGGCTCAATTGGCGGAAGCCGGCGTGCGCGT
GGACGCCGATCATCCGCTGTTCGTCTATCTGCCCTGCGGCGTGGGAGGCGGGCCCGGCGGCGTGGCCTTCGGGCTCAAGC
AGGCCTTCGGCGACGCGGTCCATTGCCTGTTCGCGGAACCCACCCGCTCGCCCTGCATGCTGCTGGGCGTGCTCACCGGC
CTGCATGACAAGGTCTCGGTGCAGGACTTCGGCATCGACAACCGCACCGTCGCGGACGGTCTGGCCGTCGGCCGGCCGTC
GGGATTCGTCGGCCGCGCGATGCAGAGGCTGATAGACGGCTATTACACGGTGGACGACGATGAGCTGTTCCGCCTGCTGG
CGATGCTGGAACAGACGGAAGGCCTGCGGCTGGAGCCGTCGGCGCTGGCAGGCGCGCCGGGCATCGCCCGCGTGCTGGAG
GAAAACCAGGGCTACCGCCAGCGCATGGGGCTGGACGCGGATCGCCTCGCCTGCGCCACCCATCTGATCTGGGCGACCGG
CGGCAGCATGGTGCCGGAAGCGGAGATGGACGGCTACCTGCGGCGCGGCCGCGCGCTGCTGGGCTGA

Upstream 100 bases:

>100_bases
TGGTCAGCCGTCGCTTGAGGATTCATCCTTTGCCAGCCGTCCGGGGCTGTCGTTTAATGGCGGCCTCCACCGGACACGGC
AAGCAGGACAGGAAACCCAC

Downstream 100 bases:

>100_bases
GGCCGATGCGCTCCGCACGGCTGGATGGCGGCCAGTTTGCCAATCTCCACACTTTCCTGGCGGTCGCCCGCCGGCTGAGC
TTCGCCGCCGCCGCCGACGA

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MIHGKTLAEWQQSHPEIRELTGLRECAWFNPAAAPAAEALPDVGLGAADIADASARLRRFAPYISRAFPETAASGGIIES
PLLPVPAFQQALARRRGRELPGRLWLKADSHLPISGSIKARGGIYEVLKHAEDLALANGLLQPGDDYARLASPEARSLFS
RHGIAVGSTGNLGLSIGIMAAKLGFQAAVHMSADARQWKKDKLRAHGVTVVEYQTDYSAAVARGREQAARDPDCHFVDDE
NSIHLFLGYAVAAERLKAQLAEAGVRVDADHPLFVYLPCGVGGGPGGVAFGLKQAFGDAVHCLFAEPTRSPCMLLGVLTG
LHDKVSVQDFGIDNRTVADGLAVGRPSGFVGRAMQRLIDGYYTVDDDELFRLLAMLEQTEGLRLEPSALAGAPGIARVLE
ENQGYRQRMGLDADRLACATHLIWATGGSMVPEAEMDGYLRRGRALLG

Sequences:

>Translated_448_residues
MIHGKTLAEWQQSHPEIRELTGLRECAWFNPAAAPAAEALPDVGLGAADIADASARLRRFAPYISRAFPETAASGGIIES
PLLPVPAFQQALARRRGRELPGRLWLKADSHLPISGSIKARGGIYEVLKHAEDLALANGLLQPGDDYARLASPEARSLFS
RHGIAVGSTGNLGLSIGIMAAKLGFQAAVHMSADARQWKKDKLRAHGVTVVEYQTDYSAAVARGREQAARDPDCHFVDDE
NSIHLFLGYAVAAERLKAQLAEAGVRVDADHPLFVYLPCGVGGGPGGVAFGLKQAFGDAVHCLFAEPTRSPCMLLGVLTG
LHDKVSVQDFGIDNRTVADGLAVGRPSGFVGRAMQRLIDGYYTVDDDELFRLLAMLEQTEGLRLEPSALAGAPGIARVLE
ENQGYRQRMGLDADRLACATHLIWATGGSMVPEAEMDGYLRRGRALLG
>Mature_448_residues
MIHGKTLAEWQQSHPEIRELTGLRECAWFNPAAAPAAEALPDVGLGAADIADASARLRRFAPYISRAFPETAASGGIIES
PLLPVPAFQQALARRRGRELPGRLWLKADSHLPISGSIKARGGIYEVLKHAEDLALANGLLQPGDDYARLASPEARSLFS
RHGIAVGSTGNLGLSIGIMAAKLGFQAAVHMSADARQWKKDKLRAHGVTVVEYQTDYSAAVARGREQAARDPDCHFVDDE
NSIHLFLGYAVAAERLKAQLAEAGVRVDADHPLFVYLPCGVGGGPGGVAFGLKQAFGDAVHCLFAEPTRSPCMLLGVLTG
LHDKVSVQDFGIDNRTVADGLAVGRPSGFVGRAMQRLIDGYYTVDDDELFRLLAMLEQTEGLRLEPSALAGAPGIARVLE
ENQGYRQRMGLDADRLACATHLIWATGGSMVPEAEMDGYLRRGRALLG

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=431, Percent_Identity=64.9651972157773, Blast_Score=556, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_CHRVO (Q7NUP9)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_902318.1
- ProteinModelPortal:   Q7NUP9
- SMR:   Q7NUP9
- GeneID:   2547465
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_2648
- NMPDR:   fig|243365.1.peg.2648
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- PhylomeDB:   Q7NUP9
- ProtClustDB:   PRK02991
- BioCyc:   CVIO243365:CV_2648-MONOMER
- BRENDA:   4.3.1.18
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 48001; Mature: 48001

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHGKTLAEWQQSHPEIRELTGLRECAWFNPAAAPAAEALPDVGLGAADIADASARLRRF
CCCCCHHHHHHHCCCHHHHHHCHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
APYISRAFPETAASGGIIESPLLPVPAFQQALARRRGRELPGRLWLKADSHLPISGSIKA
HHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
RGGIYEVLKHAEDLALANGLLQPGDDYARLASPEARSLFSRHGIAVGSTGNLGLSIGIMA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCEEECCCCCCCEEHHHHH
AKLGFQAAVHMSADARQWKKDKLRAHGVTVVEYQTDYSAAVARGREQAARDPDCHFVDDE
HHHHHHHEEECCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHCHHHHCCCCCCEEECCC
NSIHLFLGYAVAAERLKAQLAEAGVRVDADHPLFVYLPCGVGGGPGGVAFGLKQAFGDAV
CCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHE
HCLFAEPTRSPCMLLGVLTGLHDKVSVQDFGIDNRTVADGLAVGRPSGFVGRAMQRLIDG
EEEECCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCHHCCHHCCCCCCHHHHHHHHHHCC
YYTVDDDELFRLLAMLEQTEGLRLEPSALAGAPGIARVLEENQGYRQRMGLDADRLACAT
CEECCHHHHHHHHHHHHHCCCCEECCHHHCCCCHHHHHHHCCCCHHHHHCCCHHHHHHHH
HLIWATGGSMVPEAEMDGYLRRGRALLG
HHHHCCCCCCCCCHHHHHHHHHCHHCCC
>Mature Secondary Structure
MIHGKTLAEWQQSHPEIRELTGLRECAWFNPAAAPAAEALPDVGLGAADIADASARLRRF
CCCCCHHHHHHHCCCHHHHHHCHHHHHCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
APYISRAFPETAASGGIIESPLLPVPAFQQALARRRGRELPGRLWLKADSHLPISGSIKA
HHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCC
RGGIYEVLKHAEDLALANGLLQPGDDYARLASPEARSLFSRHGIAVGSTGNLGLSIGIMA
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHCCEEECCCCCCCEEHHHHH
AKLGFQAAVHMSADARQWKKDKLRAHGVTVVEYQTDYSAAVARGREQAARDPDCHFVDDE
HHHHHHHEEECCHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHCHHHHCCCCCCEEECCC
NSIHLFLGYAVAAERLKAQLAEAGVRVDADHPLFVYLPCGVGGGPGGVAFGLKQAFGDAV
CCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHE
HCLFAEPTRSPCMLLGVLTGLHDKVSVQDFGIDNRTVADGLAVGRPSGFVGRAMQRLIDG
EEEECCCCCCHHHHHHHHHCCCCCCCHHHCCCCCCCHHCCHHCCCCCCHHHHHHHHHHCC
YYTVDDDELFRLLAMLEQTEGLRLEPSALAGAPGIARVLEENQGYRQRMGLDADRLACAT
CEECCHHHHHHHHHHHHHCCCCEECCHHHCCCCHHHHHHHCCCCHHHHHCCCHHHHHHHH
HLIWATGGSMVPEAEMDGYLRRGRALLG
HHHHCCCCCCCCCHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782