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The map label for this gene is yscN [H]

Identifier: 34498058

GI number: 34498058

Start: 2813261

End: 2814595

Strand: Direct

Name: yscN [H]

Synonym: CV_2603

Alternate gene names: 34498058

Gene position: 2813261-2814595 (Clockwise)

Preceding gene: 34498057

Following gene: 34498059

Centisome position: 59.21

GC content: 64.79

Gene sequence:

>1335_bases
ATGCGGCTTCCAGACATCCGTCTCATCGAAAACACGCTGCGGGAACGACTGACCCTGGCCCCGGCACCGCCTGGGCAACG
CTCCGGCGTGGAACTATTCGGCCGGGTCACGGAAATCGGCCCCACCCTGCTGAAAGCCTCGCTGCCCGGCGCCAGCCTGT
CGGAGTTATGCCGGCTGGAACCTTCCGGCATCGAGGCCGAAGTGGTCGCCGTCACTGGAGACCACGTGATGCTATCGCCA
TTCAAAGAACCGCTGGGCGTCACCATCGGCAGCCGGGTCAGGCCTTCCGGCAGCCCACACCAGTTGCGCCTGGGCGATTT
CCTGCTGGGGCGGGTCGTCGACGGACTCGGCCGTCCGCTGGATGGCGACGAGCTTCCCGCCGACAGCGAGCTGCGCAGCC
TGGACGGACCCGCGCCCAATCCGCTGACCCGGCAATTGATAGACACGCCGCTGCCGCTGGGCGTCAGGGCCATCGATGGC
TTGCTGACTTGCGGCATGGGTCAGCGCATCGGCATCTTCGCCGCGGCGGGCGGCGGCAAGAGCACGTTGCTGGGCATGAT
CTGCGACGGCAGCCTTGCCGACGTCATCGTGCTGGCGCTGATTGGCGAACGGGGCCGTGAGGTGCGTGAATTCCTCGAAC
ATACCTTGTCGGAGGAGGCTCGGTCCCGCTCCATCGTAGTGGTGTCGACATCGGACCGTCCGGCGCTGGAACGGCTGAAA
GCCGCCTACACCGCCACCGCCATCGCCGAGCATTTCCGCGACCAGGGTAAGAACGTACTGTTAATGATGGACTCCCTGAC
CCGTTTTGCCCGCGCCTCGCGCGAGATCGGCCTGGCCGCGGGAGAACCCGCCGCTGCCGGCGGCTATCCGCCAAGCTTCT
TCGCCCGCCTGCCCCGCCTGCTGGAACGGGCCGGTCCGGCTGAAACCGGCAGCATCACCGGCATCTACACCGTTCTGGTC
GAGGGCGACAACCTCAACGAACCAGTCGCGGATGAAGTCCGCTCCATTCTGGATGGCCACATCGTGCTGTCGCGCAAGCT
GGCCGAGACCAACCACTACCCGGCCATCGATATCGGCGCCAGCGTCAGCCGGATCATGGGCCAGATCGTCAGCGCCGAAC
ACCGCCAACAGGCCGGCAAATTGCGCCGGTTGATGGCCGCGTACAAGGAAATCGAGCTATTGGTCCGGGTGGGTGAGTAC
CAACCTGGCCAGGATGCAGAAGCGGACGAGGCGCTGGAACGCAAGGACGCGATCCGGCAATTCCTTTGCCAATCCGTCAC
CGAAAAGAACGACTTTGAAGAAACACTGGAACAGCTATGGCAGACAGTCGACTGA

Upstream 100 bases:

>100_bases
AGAGAATTCTTCAACTTGCACGTGTTGTCGTTTCAGGAAATCGGCGAAGAAGCGGAATTGCGCGTGGTCGGCAATATCGA
CCTGATCGGGGAGTATTAGG

Downstream 100 bases:

>100_bases
CCTTGGCCACTCTGCTGTCTCTCAAGCAAAGGCGCGAACGCGGCATCCGGGCGGCCATCGCCAAACTGGAACAGCGGGAA
GCCGATCTGAACGGCCATAA

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLEPSGIEAEVVAVTGDHVMLSP
FKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPLDGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDG
LLTCGMGQRIGIFAAAGGGKSTLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRLLERAGPAETGSITGIYTVLV
EGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGASVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEY
QPGQDAEADEALERKDAIRQFLCQSVTEKNDFEETLEQLWQTVD

Sequences:

>Translated_444_residues
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLEPSGIEAEVVAVTGDHVMLSP
FKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPLDGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDG
LLTCGMGQRIGIFAAAGGGKSTLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRLLERAGPAETGSITGIYTVLV
EGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGASVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEY
QPGQDAEADEALERKDAIRQFLCQSVTEKNDFEETLEQLWQTVD
>Mature_444_residues
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLEPSGIEAEVVAVTGDHVMLSP
FKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPLDGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDG
LLTCGMGQRIGIFAAAGGGKSTLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRLLERAGPAETGSITGIYTVLV
EGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGASVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEY
QPGQDAEADEALERKDAIRQFLCQSVTEKNDFEETLEQLWQTVD

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=353, Percent_Identity=29.4617563739377, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI50345984, Length=429, Percent_Identity=27.039627039627, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI4757810, Length=429, Percent_Identity=27.039627039627, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI19913424, Length=243, Percent_Identity=33.7448559670782, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI19913428, Length=430, Percent_Identity=25.3488372093023, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913426, Length=432, Percent_Identity=24.0740740740741, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI1788251, Length=429, Percent_Identity=46.6200466200466, Blast_Score=337, Evalue=9e-94,
Organism=Escherichia coli, GI1790170, Length=350, Percent_Identity=28.8571428571429, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1790172, Length=363, Percent_Identity=28.6501377410468, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1790217, Length=323, Percent_Identity=28.4829721362229, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71988080, Length=436, Percent_Identity=27.7522935779816, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71988063, Length=436, Percent_Identity=27.7522935779816, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI25144756, Length=354, Percent_Identity=29.0960451977401, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17565854, Length=246, Percent_Identity=35.7723577235772, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71988074, Length=323, Percent_Identity=28.1733746130031, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=436, Percent_Identity=23.6238532110092, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=357, Percent_Identity=26.0504201680672, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319370, Length=427, Percent_Identity=29.7423887587822, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322581, Length=353, Percent_Identity=30.5949008498584, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319603, Length=438, Percent_Identity=25.5707762557078, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320016, Length=279, Percent_Identity=29.0322580645161, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24638766, Length=354, Percent_Identity=29.0960451977401, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24658560, Length=431, Percent_Identity=28.538283062645, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28574560, Length=354, Percent_Identity=29.9435028248588, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583992, Length=279, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24583988, Length=291, Percent_Identity=31.6151202749141, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583986, Length=291, Percent_Identity=31.6151202749141, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583984, Length=291, Percent_Identity=31.6151202749141, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129479, Length=260, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281361666, Length=410, Percent_Identity=24.6341463414634, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646341, Length=410, Percent_Identity=24.6341463414634, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136796, Length=410, Percent_Identity=24.6341463414634, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 47920; Mature: 47920

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLE
CCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHCCC
PSGIEAEVVAVTGDHVMLSPFKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPL
CCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
DGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDGLLTCGMGQRIGIFAAAGGGK
CCCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
STLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
HHEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRL
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LERAGPAETGSITGIYTVLVEGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGA
HHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCH
SVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEYQPGQDAEADEALERKDAIRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FLCQSVTEKNDFEETLEQLWQTVD
HHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRLPDIRLIENTLRERLTLAPAPPGQRSGVELFGRVTEIGPTLLKASLPGASLSELCRLE
CCCCCHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCCHHHHHCCC
PSGIEAEVVAVTGDHVMLSPFKEPLGVTIGSRVRPSGSPHQLRLGDFLLGRVVDGLGRPL
CCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCC
DGDELPADSELRSLDGPAPNPLTRQLIDTPLPLGVRAIDGLLTCGMGQRIGIFAAAGGGK
CCCCCCCCCHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
STLLGMICDGSLADVIVLALIGERGREVREFLEHTLSEEARSRSIVVVSTSDRPALERLK
HHEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHH
AAYTATAIAEHFRDQGKNVLLMMDSLTRFARASREIGLAAGEPAAAGGYPPSFFARLPRL
HHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LERAGPAETGSITGIYTVLVEGDNLNEPVADEVRSILDGHIVLSRKLAETNHYPAIDIGA
HHHCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCH
SVSRIMGQIVSAEHRQQAGKLRRLMAAYKEIELLVRVGEYQPGQDAEADEALERKDAIRQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FLCQSVTEKNDFEETLEQLWQTVD
HHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]