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The map label for this gene is cdd [H]

Identifier: 34498025

GI number: 34498025

Start: 2772463

End: 2772963

Strand: Direct

Name: cdd [H]

Synonym: CV_2570

Alternate gene names: 34498025

Gene position: 2772463-2772963 (Clockwise)

Preceding gene: 34498024

Following gene: 34498026

Centisome position: 58.35

GC content: 64.47

Gene sequence:

>501_bases
TTGACAAGGCCACGCCCCCTGGCGCATCATCCGGCGCCGACCTGGTTTTATGGAGGCAGCATGACCAGCAAGCAGCAAAT
ACCCAGCAATGAACAGTGGGCCGAACTGGAAATGGCCGCGCAACTGGCCGCCCGCCAGGCTTACGCGCCCTATAGCCGCT
TCACCGTCGGCGCCGCCATCCTGGACGGCAACGGCAAGATACACATCGGCTGCAATGTGGAAAACGCCTCCTACGGCCTG
AGCAACTGCGCGGAGCGCACCGCGATCTTCGCCGCCCGCGCCAACCACGGCATGCAGGAAGTGGTGGCGGTTTGCATCTA
CACCCCCACCGACAAGCCTGCCTCGCCTTGCGGCGCCTGCCGCCAGGTGCTGAACGAATTCGGTCCGACGATGCGCGTGC
GCTCGATCTGCGACGGCGAAGACATCATCGACACCACGCTGGACGCGCTGCTGCCCTCCGCCTTCGGTCCCAAGAATCTT
CAGGACGCCAGCCAGCGTTGA

Upstream 100 bases:

>100_bases
GACTACTGCGGCCGCCACTTGCGCCAGGACAAAGTGGCATATCATGCATCTGTTGGAGAATCACGGCAGAACCCCTGACC
CAAGCGGCGCGGCTGTCGCA

Downstream 100 bases:

>100_bases
GCCGCTGTCCGACTTCCATCCAACGGGAACCCGCGGGTTCCCGTTTTTCATGCCCGCGAAAAGGTTCCCCTGCGCCCGCC
TCTCTTAGGGACAGCTGAAA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTRPRPLAHHPAPTWFYGGSMTSKQQIPSNEQWAELEMAAQLAARQAYAPYSRFTVGAAILDGNGKIHIGCNVENASYGL
SNCAERTAIFAARANHGMQEVVAVCIYTPTDKPASPCGACRQVLNEFGPTMRVRSICDGEDIIDTTLDALLPSAFGPKNL
QDASQR

Sequences:

>Translated_166_residues
MTRPRPLAHHPAPTWFYGGSMTSKQQIPSNEQWAELEMAAQLAARQAYAPYSRFTVGAAILDGNGKIHIGCNVENASYGL
SNCAERTAIFAARANHGMQEVVAVCIYTPTDKPASPCGACRQVLNEFGPTMRVRSICDGEDIIDTTLDALLPSAFGPKNL
QDASQR
>Mature_165_residues
TRPRPLAHHPAPTWFYGGSMTSKQQIPSNEQWAELEMAAQLAARQAYAPYSRFTVGAAILDGNGKIHIGCNVENASYGLS
NCAERTAIFAARANHGMQEVVAVCIYTPTDKPASPCGACRQVLNEFGPTMRVRSICDGEDIIDTTLDALLPSAFGPKNLQ
DASQR

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=128, Percent_Identity=46.875, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540514, Length=140, Percent_Identity=44.2857142857143, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17551074, Length=145, Percent_Identity=42.7586206896552, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323274, Length=137, Percent_Identity=39.4160583941606, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582741, Length=138, Percent_Identity=38.4057971014493, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24582744, Length=99, Percent_Identity=46.4646464646465, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920920, Length=97, Percent_Identity=47.4226804123711, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 17955; Mature: 17824

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPRPLAHHPAPTWFYGGSMTSKQQIPSNEQWAELEMAAQLAARQAYAPYSRFTVGAAI
CCCCCCCCCCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEE
LDGNGKIHIGCNVENASYGLSNCAERTAIFAARANHGMQEVVAVCIYTPTDKPASPCGAC
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCHHHHH
RQVLNEFGPTMRVRSICDGEDIIDTTLDALLPSAFGPKNLQDASQR
HHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRPRPLAHHPAPTWFYGGSMTSKQQIPSNEQWAELEMAAQLAARQAYAPYSRFTVGAAI
CCCCCCCCCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEE
LDGNGKIHIGCNVENASYGLSNCAERTAIFAARANHGMQEVVAVCIYTPTDKPASPCGAC
ECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCHHHHH
RQVLNEFGPTMRVRSICDGEDIIDTTLDALLPSAFGPKNLQDASQR
HHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]