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The map label for this gene is evgS [H]

Identifier: 34497855

GI number: 34497855

Start: 2583139

End: 2585502

Strand: Reverse

Name: evgS [H]

Synonym: CV_2400

Alternate gene names: 34497855

Gene position: 2585502-2583139 (Counterclockwise)

Preceding gene: 34497856

Following gene: 34497853

Centisome position: 54.42

GC content: 64.93

Gene sequence:

>2364_bases
ATGAGGCTGTCAGGGCTGCATCGATGGCTGCTGGCCATGTCGCTGGCGTTCTGCTCCGGATCGAGCGTGGCCGCGAGCCC
GTTCAACGCAGGAGAGCAAGCCTGGCTGGCCAACCATCCTGTGGTTCGCTACGCAATAGATCCCCACGGCTGGCCGATAG
AATACCTGGACGACGGCGAGCACAAGGGTCTGACCCAGGAGTACCTGCAACGCATCGCGGACATCACCGGCATCCGGTTC
CAGCTGGTGCAGGTGCAAAACCGCCACCAGGCGATGGGCTTGATGCTGAGAGGCAAGCTGGACCTGCTCACCGCGACCTC
CCCCAGGCTGATCCCGCCGCCGTTCAACAAGCAGATCCTGTTCAGCGATCCCTACTTTTCCGGCAGCACACTGCTTGTCA
CGCGCGCGGACAAGCCCATCGTGTTCGATCCGGCCAAGCTGTCGGGCAAAACCGTGGCCGTGGAGCAAGGCGACCCGTAC
GAATACTTCCTGCGCGAGCACTATCCGGAAATCAAGATCGTCCAGACCACCACCCCGCTGGGCGCGCTGGACGCCGTCGC
CGATGGGGACGCCTATGCGGCGGTCGGTCTGGACGCCATTCTCCAGAGCGTGATCCAGCGACGCTATTACGGGACACTGC
ACATCGCGGGCAGCGTCAGCGAGATGCCGCGGCTGGTTTCGATGGCGGTCAGCCTGCAGCAGCCGATGCTGCGCGACATC
ATCAACAAATCGCTCGGACAGCTGACCGCCGAGGACACCGACAACATCCTGTACAACTGGCTGCGCACCACCGACTACGG
CACGCCGACCGTGGGTTCCATCGTCCGTCACTACTGGATAGAGCTTTCGCTGCTGGCCGTCGCGCTCTGCCTGCTGCTGC
TGTTCGCCCAGCACGCCCGCTCCGCCAAGCGCGCGGCCCAGCGCAGCGAGGCTGAGAAATCGATGTTTCTCGCGATGATG
AGCCACGAGATACGCACGCCGCTGAACGCCGTGCTGGCCTCGGTCGAATTATTGCGCGGCAGCATGCTGCCGCCCCGCGA
ACGGGAGTTGGTGGCTTTGGCCAACGCCTCGGCAGTGAATCTGCTGGAGCTGCTGGACAACGTTCTGGACATCGCCAAGC
TGGATGCCCACAAGCTGATGCTTGAGCCGGTCCTGGTGGACATGGCGGCGCTGGCCAGCGGCGTGGCCGGCATCTATCGC
CCCTGCGCCGAAAAGAAGGGACTGGCGCTGACCACCCAGTTGTCGGGATTGGCGGGCCTGCGCGTATGGCTGGACCCCGT
GCGCATGCGACAAATATTGAGCAACCTGCTCAGCAACGCCGTCAAGTTCACCCATCAGGGCGAGATTCTGCTGCGCGTGG
AACTGCTTCCGGGCGACGCCGGCAGCGGAACCTTGCTGATCATGGTGCAGGATACCGGCATCGGCATCGCACTGGAGCAG
CAAGGCAGGTTGTTCACCGCCTACGCCCAGGCAGGCGACAGCCGGCAGGGGTACGGCGGCTCCGGGCTGGGATTGGTCAT
ATGCAGGCAACTGGTTGAATTGATGGCCGGCAGCATTTCGCTGTCCAGCCTGCCTGGATGCGGCACCACCATGACGCTGA
GGCTGCCGGTAGAGTGGGAGCCGGCGCCGGCGATGGAGCCTCCCCAGGCCATTGAGCGTCGCCCCGGACTGCTTCAGGCC
TATGACCCGATACTGGTGGTGGAAGACCAGCCGGCGAATCGCTTCGTGATCGGCCAGCAACTGGAAACGCTGGGCTTTCG
CTCGGTGATGGCCGAAGATGCCCCGGCGGCGCTGGCCCTGCTGGATCAGGGCGGCCGCTTCTCCATGGTGCTGCTGGACT
GCAACCTGCCAGGCATCGACGGCTATGAGCTGGCCAGACGCTTGCGCCAGCATCCGGCCCTGCAATGGCAGCCCTATCTG
CCCATCGTCGCGATCTCCGCGACCACCGGCATCGAGCACCAGCAACGCTGCCTGGAAAGCGGCATGGACAGCTGCCTGTC
AAAACCTCTGCAGCTGGCCCAGCTGGAAAACATCCTGGCGCTGTGGCTGGACCACCACCCGGCGGGCGAGGTCCACGAAA
GCGCCGCGATCCATGGAGAGAGTTTCGACGCGGTGTTTCGCCGCAGCGCCGGCGAGGATGTCTCACGGTTTGGACTGGCG
CTGTCCCAGGGAGACTGGAAGCAGGCCGATCATTACGCGCACCGCCTGCATGGCGCGGCGCTGAGCGCCGGCCGGTCGGA
ACTGGCCGCCACCGCGGAACGGATGCAGAACGCCCTGCGTGACGCCCAGCCGGATCAGGCCTTGCTGCGCGCCCTGCAGG
AAGAGGCCGACTGCCTGCTGAACGCCGCTCCGCCTTCGCCATGA

Upstream 100 bases:

>100_bases
GCATCAAGACGATCAGCAATCAGAAACAATCGGCGCTCAAGAAGCTGGGCCTGCGCAGCGACAACGAGCTATTCCTGCAA
CAACAACGGCTGGAAGGGCA

Downstream 100 bases:

>100_bases
GCGCCGCAGCGGCGCGCTAGCGTCCCGCATCCGTCAGGCGCAGGCTCAACAGCTCCAGCTCTCTCATCTGCCGGCCAAGC
AGCCTGTCCAGCGCGGCCTG

Product: sensor protein evgS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MRLSGLHRWLLAMSLAFCSGSSVAASPFNAGEQAWLANHPVVRYAIDPHGWPIEYLDDGEHKGLTQEYLQRIADITGIRF
QLVQVQNRHQAMGLMLRGKLDLLTATSPRLIPPPFNKQILFSDPYFSGSTLLVTRADKPIVFDPAKLSGKTVAVEQGDPY
EYFLREHYPEIKIVQTTTPLGALDAVADGDAYAAVGLDAILQSVIQRRYYGTLHIAGSVSEMPRLVSMAVSLQQPMLRDI
INKSLGQLTAEDTDNILYNWLRTTDYGTPTVGSIVRHYWIELSLLAVALCLLLLFAQHARSAKRAAQRSEAEKSMFLAMM
SHEIRTPLNAVLASVELLRGSMLPPRERELVALANASAVNLLELLDNVLDIAKLDAHKLMLEPVLVDMAALASGVAGIYR
PCAEKKGLALTTQLSGLAGLRVWLDPVRMRQILSNLLSNAVKFTHQGEILLRVELLPGDAGSGTLLIMVQDTGIGIALEQ
QGRLFTAYAQAGDSRQGYGGSGLGLVICRQLVELMAGSISLSSLPGCGTTMTLRLPVEWEPAPAMEPPQAIERRPGLLQA
YDPILVVEDQPANRFVIGQQLETLGFRSVMAEDAPAALALLDQGGRFSMVLLDCNLPGIDGYELARRLRQHPALQWQPYL
PIVAISATTGIEHQQRCLESGMDSCLSKPLQLAQLENILALWLDHHPAGEVHESAAIHGESFDAVFRRSAGEDVSRFGLA
LSQGDWKQADHYAHRLHGAALSAGRSELAATAERMQNALRDAQPDQALLRALQEEADCLLNAAPPSP

Sequences:

>Translated_787_residues
MRLSGLHRWLLAMSLAFCSGSSVAASPFNAGEQAWLANHPVVRYAIDPHGWPIEYLDDGEHKGLTQEYLQRIADITGIRF
QLVQVQNRHQAMGLMLRGKLDLLTATSPRLIPPPFNKQILFSDPYFSGSTLLVTRADKPIVFDPAKLSGKTVAVEQGDPY
EYFLREHYPEIKIVQTTTPLGALDAVADGDAYAAVGLDAILQSVIQRRYYGTLHIAGSVSEMPRLVSMAVSLQQPMLRDI
INKSLGQLTAEDTDNILYNWLRTTDYGTPTVGSIVRHYWIELSLLAVALCLLLLFAQHARSAKRAAQRSEAEKSMFLAMM
SHEIRTPLNAVLASVELLRGSMLPPRERELVALANASAVNLLELLDNVLDIAKLDAHKLMLEPVLVDMAALASGVAGIYR
PCAEKKGLALTTQLSGLAGLRVWLDPVRMRQILSNLLSNAVKFTHQGEILLRVELLPGDAGSGTLLIMVQDTGIGIALEQ
QGRLFTAYAQAGDSRQGYGGSGLGLVICRQLVELMAGSISLSSLPGCGTTMTLRLPVEWEPAPAMEPPQAIERRPGLLQA
YDPILVVEDQPANRFVIGQQLETLGFRSVMAEDAPAALALLDQGGRFSMVLLDCNLPGIDGYELARRLRQHPALQWQPYL
PIVAISATTGIEHQQRCLESGMDSCLSKPLQLAQLENILALWLDHHPAGEVHESAAIHGESFDAVFRRSAGEDVSRFGLA
LSQGDWKQADHYAHRLHGAALSAGRSELAATAERMQNALRDAQPDQALLRALQEEADCLLNAAPPSP
>Mature_787_residues
MRLSGLHRWLLAMSLAFCSGSSVAASPFNAGEQAWLANHPVVRYAIDPHGWPIEYLDDGEHKGLTQEYLQRIADITGIRF
QLVQVQNRHQAMGLMLRGKLDLLTATSPRLIPPPFNKQILFSDPYFSGSTLLVTRADKPIVFDPAKLSGKTVAVEQGDPY
EYFLREHYPEIKIVQTTTPLGALDAVADGDAYAAVGLDAILQSVIQRRYYGTLHIAGSVSEMPRLVSMAVSLQQPMLRDI
INKSLGQLTAEDTDNILYNWLRTTDYGTPTVGSIVRHYWIELSLLAVALCLLLLFAQHARSAKRAAQRSEAEKSMFLAMM
SHEIRTPLNAVLASVELLRGSMLPPRERELVALANASAVNLLELLDNVLDIAKLDAHKLMLEPVLVDMAALASGVAGIYR
PCAEKKGLALTTQLSGLAGLRVWLDPVRMRQILSNLLSNAVKFTHQGEILLRVELLPGDAGSGTLLIMVQDTGIGIALEQ
QGRLFTAYAQAGDSRQGYGGSGLGLVICRQLVELMAGSISLSSLPGCGTTMTLRLPVEWEPAPAMEPPQAIERRPGLLQA
YDPILVVEDQPANRFVIGQQLETLGFRSVMAEDAPAALALLDQGGRFSMVLLDCNLPGIDGYELARRLRQHPALQWQPYL
PIVAISATTGIEHQQRCLESGMDSCLSKPLQLAQLENILALWLDHHPAGEVHESAAIHGESFDAVFRRSAGEDVSRFGLA
LSQGDWKQADHYAHRLHGAALSAGRSELAATAERMQNALRDAQPDQALLRALQEEADCLLNAAPPSP

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=451, Percent_Identity=33.4811529933481, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI48994928, Length=494, Percent_Identity=29.9595141700405, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=38.7096774193548, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=35.6589147286822, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081816, Length=472, Percent_Identity=29.4491525423729, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=28.936170212766, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=29.3103448275862, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=30.1724137931034, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=282, Percent_Identity=28.0141843971631, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=25.9842519685039, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1790436, Length=114, Percent_Identity=35.9649122807018, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85894; Mature: 85894

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSGLHRWLLAMSLAFCSGSSVAASPFNAGEQAWLANHPVVRYAIDPHGWPIEYLDDGE
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCEEECCCCC
HKGLTQEYLQRIADITGIRFQLVQVQNRHQAMGLMLRGKLDLLTATSPRLIPPPFNKQIL
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCCCEE
FSDPYFSGSTLLVTRADKPIVFDPAKLSGKTVAVEQGDPYEYFLREHYPEIKIVQTTTPL
EECCCCCCCEEEEEECCCCEEECCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCC
GALDAVADGDAYAAVGLDAILQSVIQRRYYGTLHIAGSVSEMPRLVSMAVSLQQPMLRDI
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
INKSLGQLTAEDTDNILYNWLRTTDYGTPTVGSIVRHYWIELSLLAVALCLLLLFAQHAR
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKRAAQRSEAEKSMFLAMMSHEIRTPLNAVLASVELLRGSMLPPRERELVALANASAVN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
LLELLDNVLDIAKLDAHKLMLEPVLVDMAALASGVAGIYRPCAEKKGLALTTQLSGLAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
RVWLDPVRMRQILSNLLSNAVKFTHQGEILLRVELLPGDAGSGTLLIMVQDTGIGIALEQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEC
QGRLFTAYAQAGDSRQGYGGSGLGLVICRQLVELMAGSISLSSLPGCGTTMTLRLPVEWE
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECC
PAPAMEPPQAIERRPGLLQAYDPILVVEDQPANRFVIGQQLETLGFRSVMAEDAPAALAL
CCCCCCCCHHHHHCCCCEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEEHE
LDQGGRFSMVLLDCNLPGIDGYELARRLRQHPALQWQPYLPIVAISATTGIEHQQRCLES
ECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
GMDSCLSKPLQLAQLENILALWLDHHPAGEVHESAAIHGESFDAVFRRSAGEDVSRFGLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHCCC
LSQGDWKQADHYAHRLHGAALSAGRSELAATAERMQNALRDAQPDQALLRALQEEADCLL
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
NAAPPSP
CCCCCCC
>Mature Secondary Structure
MRLSGLHRWLLAMSLAFCSGSSVAASPFNAGEQAWLANHPVVRYAIDPHGWPIEYLDDGE
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCEEEEEECCCCCCEEECCCCC
HKGLTQEYLQRIADITGIRFQLVQVQNRHQAMGLMLRGKLDLLTATSPRLIPPPFNKQIL
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEECCEEEEECCCCCCCCCCCCCCEE
FSDPYFSGSTLLVTRADKPIVFDPAKLSGKTVAVEQGDPYEYFLREHYPEIKIVQTTTPL
EECCCCCCCEEEEEECCCCEEECCCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCC
GALDAVADGDAYAAVGLDAILQSVIQRRYYGTLHIAGSVSEMPRLVSMAVSLQQPMLRDI
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
INKSLGQLTAEDTDNILYNWLRTTDYGTPTVGSIVRHYWIELSLLAVALCLLLLFAQHAR
HHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKRAAQRSEAEKSMFLAMMSHEIRTPLNAVLASVELLRGSMLPPRERELVALANASAVN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
LLELLDNVLDIAKLDAHKLMLEPVLVDMAALASGVAGIYRPCAEKKGLALTTQLSGLAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
RVWLDPVRMRQILSNLLSNAVKFTHQGEILLRVELLPGDAGSGTLLIMVQDTGIGIALEQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEC
QGRLFTAYAQAGDSRQGYGGSGLGLVICRQLVELMAGSISLSSLPGCGTTMTLRLPVEWE
CCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECC
PAPAMEPPQAIERRPGLLQAYDPILVVEDQPANRFVIGQQLETLGFRSVMAEDAPAALAL
CCCCCCCCHHHHHCCCCEEECCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEEHE
LDQGGRFSMVLLDCNLPGIDGYELARRLRQHPALQWQPYLPIVAISATTGIEHQQRCLES
ECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
GMDSCLSKPLQLAQLENILALWLDHHPAGEVHESAAIHGESFDAVFRRSAGEDVSRFGLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHCCC
LSQGDWKQADHYAHRLHGAALSAGRSELAATAERMQNALRDAQPDQALLRALQEEADCLL
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEE
NAAPPSP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]