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The map label for this gene is frwB [H]

Identifier: 34497765

GI number: 34497765

Start: 2502476

End: 2502769

Strand: Direct

Name: frwB [H]

Synonym: CV_2310

Alternate gene names: 34497765

Gene position: 2502476-2502769 (Clockwise)

Preceding gene: 34497764

Following gene: 34497766

Centisome position: 52.67

GC content: 62.93

Gene sequence:

>294_bases
ATGAAAGTAGTCGCCATCACCGCCTGCCCGACCGGCATCGCCCACACCTATATGGCCGCGGAAAAGCTGGAAAGCACAGG
CCGCCGGCTGGGACACGACGTCAAGGTGGAAACCCAGGGCGCGATAGGCATAGAGAACGAGCTGTCCAGCCGCGACATCC
AGGCGGCCGACGTGGTGCTGCTGGCGGTGGACATCGCCATCGAGGGCGAGGAACGCTTTGAGGACAAGCGCGTGGTGCGG
GTGCCGATCCAGAATGTGCTGAAAGACGCCAATGCGGTTTTCGCGCTCCTGTGA

Upstream 100 bases:

>100_bases
TCGCCGTCGTCATCAACCTGCTCCGGGCCAGGAGCGCCGCTCCGGCCGAATCCGCTCCGGCCGCCTGAGCCGCCGAATCA
CCGTCACAAGGAAACCGATC

Downstream 100 bases:

>100_bases
ACCCGGCCGGGCCGCGGCGCCCGGCGCATAAGGAAGCAGTCGTATGTCACACAGCCTTACCCTGGTTTGCCCGCTGCCCA
ATGGCATCCATGCCCGCCCC

Product: PTS system, fructose-like-2 IIB component 1

Products: NA

Alternate protein names: PTS system fructose-like EIIB component 2 [H]

Number of amino acids: Translated: 97; Mature: 97

Protein sequence:

>97_residues
MKVVAITACPTGIAHTYMAAEKLESTGRRLGHDVKVETQGAIGIENELSSRDIQAADVVLLAVDIAIEGEERFEDKRVVR
VPIQNVLKDANAVFALL

Sequences:

>Translated_97_residues
MKVVAITACPTGIAHTYMAAEKLESTGRRLGHDVKVETQGAIGIENELSSRDIQAADVVLLAVDIAIEGEERFEDKRVVR
VPIQNVLKDANAVFALL
>Mature_97_residues
MKVVAITACPTGIAHTYMAAEKLESTGRRLGHDVKVETQGAIGIENELSSRDIQAADVVLLAVDIAIEGEERFEDKRVVR
VPIQNVLKDANAVFALL

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1445

COG function: function code G; Phosphotransferase system fructose-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=55.3191489361702, Blast_Score=115, Evalue=7e-28,
Organism=Escherichia coli, GI87082348, Length=99, Percent_Identity=50.5050505050505, Blast_Score=102, Evalue=3e-24,
Organism=Escherichia coli, GI1788730, Length=93, Percent_Identity=41.9354838709677, Blast_Score=89, Evalue=6e-20,
Organism=Escherichia coli, GI1790390, Length=93, Percent_Identity=48.3870967741936, Blast_Score=89, Evalue=8e-20,
Organism=Escherichia coli, GI1786951, Length=91, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=2e-19,
Organism=Escherichia coli, GI1788492, Length=87, Percent_Identity=43.6781609195402, Blast_Score=80, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003353 [H]

Pfam domain/function: PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 10500; Mature: 10500

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVAITACPTGIAHTYMAAEKLESTGRRLGHDVKVETQGAIGIENELSSRDIQAADVVL
CEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHEEEE
LAVDIAIEGEERFEDKRVVRVPIQNVLKDANAVFALL
EEEEEEECCHHHCCCCCEEEECHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKVVAITACPTGIAHTYMAAEKLESTGRRLGHDVKVETQGAIGIENELSSRDIQAADVVL
CEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCHHEEEE
LAVDIAIEGEERFEDKRVVRVPIQNVLKDANAVFALL
EEEEEEECCHHHCCCCCEEEECHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]