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The map label for this gene is fucP [H]

Identifier: 34497703

GI number: 34497703

Start: 2436326

End: 2437549

Strand: Direct

Name: fucP [H]

Synonym: CV_2248

Alternate gene names: 34497703

Gene position: 2436326-2437549 (Clockwise)

Preceding gene: 34497702

Following gene: 34497704

Centisome position: 51.28

GC content: 62.91

Gene sequence:

>1224_bases
ATGAATCGTGATGACGCGCTGTTGAGAAAAACCATCATTCTGGTGACCTGCACCTTCTTCCTGTGGGGCATGTCCTATGG
CTTGCTGGATGTGCTGAACAAGCATTTCCAGCAGGCCATGCGGCTGTCCAAGGCCGACTCCGGCTGGCTGCAGATCGCCT
ATTTCCTGGCCTATTTCGTGATTGCCATCCCGGCCGCGCTGTTCAATGAACGCTTTGGCTACAAGCGCGGGCTGATCGCC
GGGCTGTGCTTCTTCGCGACCGGGGCGCTGCTGTTCATCCCGTCGCTGCTGAACGCCAGCTTCCTGGCCTTCGTGCTGTC
GCTGTTCGTGCTGGCCTGCGGATCCGGCTTCCTGGAAACCACCGCCAATCCGTACATCTCGCTGCTGGGCGACGAAAGCC
GCTCGGAGCGGCGGCTGAACCTGGCGCAGGCCTTTTGCGGACTCGGCACGGTGGTGGGGCCGCTGATCGGCGGAGCCTTC
TTCTTCAAGCTGGGCAATAGCGCGACTTCGGGCGCGCAGCACGATATGGTGATGCAGGTCTATGTGTGGATCGCGGCATT
CGTGGCGCTGCTGGCGCTGGCCATCGCCCGAACGCCGATGCCGGACGCGGGCCACTGCCAGGCCGAAGAGCGGCGCGGCG
GCCGGCCGCTGATCCGCAACGGCCGCTTCACGTTCGGCGTGCTGGCGCAGTTTCTCTACGTGGCCGCGCAGGTCGGGATC
GGCGCCTTTTTCATCAATTACGCGATGGAAAGCGGCATGGACTTGAGCGCGCAGTCTGCCGCCTGGCTGCTGTCGGTGGC
GATGCTGCTGTTCATGGCGGGGCGCTTCGTCGGCACTTTCGCCATCGGCCGCTTGTCTGCGGGACGCTTGCTGATGCTGT
TCGCCTTCGCCGACATTCTGTTGTCGCTGGCGGTGGTGACCATGGGCGGGGCCATCGCGGTGGGAGCGTTGACCCTGATG
TTTTTCTTCATGTCCATCATGTTCCCCACCATTTTCTCGCTGGCGATCAAGGGCCTGGCGCACCAGACCAAGCGGGCGAG
CTCCATCCTGGCGATGTCGGTGAGCGGAGGGGCGGTTTATCCGTACTTGATGGGTTATGTCTCCGACCATTACGGCACGC
CGCCGGCCTACGCGATTCCGCTGGCCAGTTTCGTCGTGATTTTCCTGTACAGCGTGTATCTGGAGCGTCAAAGGGCGACG
CAGCCTTTGGCCAGCGCGCTCTGA

Upstream 100 bases:

>100_bases
ATCGAGGAGAGCCTGCGCAAGTTCGACGCGGCCTGGCAAAGCAACGGGCTGATGCGGGACGCCGCGCTGTTCAAGGCGTG
AGCAAACAAGAAAGAAAATG

Downstream 100 bases:

>100_bases
ATTTCAAAAGGGGAAAAAGCAAATAAAGCGAAGCCGGCGAAAGCCGGCTTTGTTCGTTCAGGCGCGCAATTTTGCGCGCT
TGCTCGGCTTTTGGGTCAGG

Product: fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNRDDALLRKTIILVTCTFFLWGMSYGLLDVLNKHFQQAMRLSKADSGWLQIAYFLAYFVIAIPAALFNERFGYKRGLIA
GLCFFATGALLFIPSLLNASFLAFVLSLFVLACGSGFLETTANPYISLLGDESRSERRLNLAQAFCGLGTVVGPLIGGAF
FFKLGNSATSGAQHDMVMQVYVWIAAFVALLALAIARTPMPDAGHCQAEERRGGRPLIRNGRFTFGVLAQFLYVAAQVGI
GAFFINYAMESGMDLSAQSAAWLLSVAMLLFMAGRFVGTFAIGRLSAGRLLMLFAFADILLSLAVVTMGGAIAVGALTLM
FFFMSIMFPTIFSLAIKGLAHQTKRASSILAMSVSGGAVYPYLMGYVSDHYGTPPAYAIPLASFVVIFLYSVYLERQRAT
QPLASAL

Sequences:

>Translated_407_residues
MNRDDALLRKTIILVTCTFFLWGMSYGLLDVLNKHFQQAMRLSKADSGWLQIAYFLAYFVIAIPAALFNERFGYKRGLIA
GLCFFATGALLFIPSLLNASFLAFVLSLFVLACGSGFLETTANPYISLLGDESRSERRLNLAQAFCGLGTVVGPLIGGAF
FFKLGNSATSGAQHDMVMQVYVWIAAFVALLALAIARTPMPDAGHCQAEERRGGRPLIRNGRFTFGVLAQFLYVAAQVGI
GAFFINYAMESGMDLSAQSAAWLLSVAMLLFMAGRFVGTFAIGRLSAGRLLMLFAFADILLSLAVVTMGGAIAVGALTLM
FFFMSIMFPTIFSLAIKGLAHQTKRASSILAMSVSGGAVYPYLMGYVSDHYGTPPAYAIPLASFVVIFLYSVYLERQRAT
QPLASAL
>Mature_407_residues
MNRDDALLRKTIILVTCTFFLWGMSYGLLDVLNKHFQQAMRLSKADSGWLQIAYFLAYFVIAIPAALFNERFGYKRGLIA
GLCFFATGALLFIPSLLNASFLAFVLSLFVLACGSGFLETTANPYISLLGDESRSERRLNLAQAFCGLGTVVGPLIGGAF
FFKLGNSATSGAQHDMVMQVYVWIAAFVALLALAIARTPMPDAGHCQAEERRGGRPLIRNGRFTFGVLAQFLYVAAQVGI
GAFFINYAMESGMDLSAQSAAWLLSVAMLLFMAGRFVGTFAIGRLSAGRLLMLFAFADILLSLAVVTMGGAIAVGALTLM
FFFMSIMFPTIFSLAIKGLAHQTKRASSILAMSVSGGAVYPYLMGYVSDHYGTPPAYAIPLASFVVIFLYSVYLERQRAT
QPLASAL

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=426, Percent_Identity=36.6197183098592, Blast_Score=233, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44065; Mature: 44065

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]