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The map label for this gene is fepD [H]

Identifier: 34497691

GI number: 34497691

Start: 2421496

End: 2422512

Strand: Reverse

Name: fepD [H]

Synonym: CV_2236

Alternate gene names: 34497691

Gene position: 2422512-2421496 (Counterclockwise)

Preceding gene: 34497693

Following gene: 34497690

Centisome position: 50.99

GC content: 74.53

Gene sequence:

>1017_bases
TTGATTATGCAGACAAGCTCCGTCTCCGGACGCCGCGCCGCCCTGTTGCTGGCCTGCCTGGCGCTGCTGGCCGTCGCCGC
CACGCTGAGCCTGGTCCTGGGCGCCAAGCCGATTCCGCTCGCCACCGTCTGGAACAGCCTGCTGGGCCGCGACTACGGCC
CGGACAGCGTGATCGTGCTGCAAGGCCGGCTGCCGCGCACGCTGCTGGGCCTGCTGGCCGGCGCGGCGCTGGGGCTGTCC
GGCGCGCTGATCCAGGCGCTGACCCGCAATCCGCTGGCCGATCCCGGCGTGCTCGGCGTCAACGCCGGCGCCAGCTTCGC
CATGGTGCTGGGCGTCGCCTTCCTTGCCGTGGACAGCCAAGGCGGCTACATGGCCTGCGCGGCGGCGGGCGCGCTGTGCG
CGACGCTGCTGGTCTACCTCGTCGGCGCGCGCGGCCGCCGCGCCGATCCGCTGCGCATCGTGCTGGCAGGCGTCGCCGTC
GGCGCGGTGCTGATGGGCCTGTCGGCCGCCATCACCCTGCTCGATCCCATCGCCTTCAACCGGCTGCGCTACTGGAACGC
CGGCACGCTGGACGTGCGCGACATGTCCGCCGTCGCGCTGGCGGCGCCCGCCATCCTGGCCGGCGGCCTGCTGGCGCTGC
TGCTGGCCCGCCCGTTGAACGCGATGGGCCTGGGCACCGACCTCGCGGTCAGCCTGGGCGGCCGTCCGCTGCTGATCCAG
GGCGGAACCGTGGCCGCCGTCACGCTGCTGTCCGGCGCCAGTACCGCCGTCGCCGGGCCGATAGGCTTCGTCGGCCTGAT
GATTCCGCACGTCGCGCGCCGGCTGGGCGGCGCCGACCTGCGCTGGAGCCTGCCCTTCACCGCCCTGCTCGCCCCCATCT
TGCTGCTGGCCTCCGACATCGCCGGCCGGCTGCTGACGCCGGGCGAGCTGCGCGTGTCCATCGTCACCGCCTTCATCGGC
GCGCCGGCGCTGATCTGGCTGGCGCGCGGCCACGGCGGCGCGGGAGGCCGGACATGA

Upstream 100 bases:

>100_bases
ATGCGCGCCGCAGGCTGAGATGACAAGCCGCGCCATGGGCCTGTCCCTTCATGTGACAGGCATGGTAACATCGGCAGTTG
TTATTAGGAATCATTTTCAT

Downstream 100 bases:

>100_bases
AAGCGATGGCACTGCGACTGGGCCATCCCGACGGCCGCTTCAACCTCCGCCTGAGGCTGGACCGGTTGTGGCCTGGGCTG
CTGCTGATGGCGGCCTGCGC

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MIMQTSSVSGRRAALLLACLALLAVAATLSLVLGAKPIPLATVWNSLLGRDYGPDSVIVLQGRLPRTLLGLLAGAALGLS
GALIQALTRNPLADPGVLGVNAGASFAMVLGVAFLAVDSQGGYMACAAAGALCATLLVYLVGARGRRADPLRIVLAGVAV
GAVLMGLSAAITLLDPIAFNRLRYWNAGTLDVRDMSAVALAAPAILAGGLLALLLARPLNAMGLGTDLAVSLGGRPLLIQ
GGTVAAVTLLSGASTAVAGPIGFVGLMIPHVARRLGGADLRWSLPFTALLAPILLLASDIAGRLLTPGELRVSIVTAFIG
APALIWLARGHGGAGGRT

Sequences:

>Translated_338_residues
MIMQTSSVSGRRAALLLACLALLAVAATLSLVLGAKPIPLATVWNSLLGRDYGPDSVIVLQGRLPRTLLGLLAGAALGLS
GALIQALTRNPLADPGVLGVNAGASFAMVLGVAFLAVDSQGGYMACAAAGALCATLLVYLVGARGRRADPLRIVLAGVAV
GAVLMGLSAAITLLDPIAFNRLRYWNAGTLDVRDMSAVALAAPAILAGGLLALLLARPLNAMGLGTDLAVSLGGRPLLIQ
GGTVAAVTLLSGASTAVAGPIGFVGLMIPHVARRLGGADLRWSLPFTALLAPILLLASDIAGRLLTPGELRVSIVTAFIG
APALIWLARGHGGAGGRT
>Mature_338_residues
MIMQTSSVSGRRAALLLACLALLAVAATLSLVLGAKPIPLATVWNSLLGRDYGPDSVIVLQGRLPRTLLGLLAGAALGLS
GALIQALTRNPLADPGVLGVNAGASFAMVLGVAFLAVDSQGGYMACAAAGALCATLLVYLVGARGRRADPLRIVLAGVAV
GAVLMGLSAAITLLDPIAFNRLRYWNAGTLDVRDMSAVALAAPAILAGGLLALLLARPLNAMGLGTDLAVSLGGRPLLIQ
GGTVAAVTLLSGASTAVAGPIGFVGLMIPHVARRLGGADLRWSLPFTALLAPILLLASDIAGRLLTPGELRVSIVTAFIG
APALIWLARGHGGAGGRT

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=301, Percent_Identity=53.8205980066445, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1790740, Length=309, Percent_Identity=34.3042071197411, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790741, Length=273, Percent_Identity=38.0952380952381, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=41.2811387900356, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786804, Length=319, Percent_Identity=33.8557993730408, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=287, Percent_Identity=32.404181184669, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33881; Mature: 33881

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMQTSSVSGRRAALLLACLALLAVAATLSLVLGAKPIPLATVWNSLLGRDYGPDSVIVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEE
QGRLPRTLLGLLAGAALGLSGALIQALTRNPLADPGVLGVNAGASFAMVLGVAFLAVDSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHEEECC
GGYMACAAAGALCATLLVYLVGARGRRADPLRIVLAGVAVGAVLMGLSAAITLLDPIAFN
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRYWNAGTLDVRDMSAVALAAPAILAGGLLALLLARPLNAMGLGTDLAVSLGGRPLLIQ
HEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEECCCCEEEEE
GGTVAAVTLLSGASTAVAGPIGFVGLMIPHVARRLGGADLRWSLPFTALLAPILLLASDI
CCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHH
AGRLLTPGELRVSIVTAFIGAPALIWLARGHGGAGGRT
HCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MIMQTSSVSGRRAALLLACLALLAVAATLSLVLGAKPIPLATVWNSLLGRDYGPDSVIVL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEE
QGRLPRTLLGLLAGAALGLSGALIQALTRNPLADPGVLGVNAGASFAMVLGVAFLAVDSQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHEEECC
GGYMACAAAGALCATLLVYLVGARGRRADPLRIVLAGVAVGAVLMGLSAAITLLDPIAFN
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLRYWNAGTLDVRDMSAVALAAPAILAGGLLALLLARPLNAMGLGTDLAVSLGGRPLLIQ
HEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEECCCCEEEEE
GGTVAAVTLLSGASTAVAGPIGFVGLMIPHVARRLGGADLRWSLPFTALLAPILLLASDI
CCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHH
AGRLLTPGELRVSIVTAFIGAPALIWLARGHGGAGGRT
HCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]