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The map label for this gene is fepG [H]

Identifier: 34497690

GI number: 34497690

Start: 2420456

End: 2421499

Strand: Reverse

Name: fepG [H]

Synonym: CV_2235

Alternate gene names: 34497690

Gene position: 2421499-2420456 (Counterclockwise)

Preceding gene: 34497691

Following gene: 34497689

Centisome position: 50.97

GC content: 71.07

Gene sequence:

>1044_bases
ATGAAAGCGATGGCACTGCGACTGGGCCATCCCGACGGCCGCTTCAACCTCCGCCTGAGGCTGGACCGGTTGTGGCCTGG
GCTGCTGCTGATGGCGGCCTGCGCCGCACTGGCGCTGATCAGCCTGCGCGCAGGCGCCTTGCACCTGAGCATCGAGCAGG
TCTGGGCGGCCTTGCAAGGCCGCGGCAGCCGGCTGAACGTGGCGGTGGTGCAGCAATGGCGGCTGCCTCGGGTGGCGATG
GCGCTGGCGATCGGCGCGGCGCTGGGCATGAGCGGCGCGATTTTCCAGTCCTTGCTGCGCAATCCGCTGGGCAGTCCCGA
CGTGGTGGGCTTCAACACCGGCGCCTACACCGGCGCGCTGCTGGTGATCACCACCATCGGCGGCAGCCATTTCCAGATCG
CCGGCGGCGCGCTGGCCGGCGGCCTGGCCTCCGCCGCGCTGGTTTACCTGCTGGCATGGAAGCGCGGCGCGCACGGGCTC
AGGCTGATCATCGTCGGCATCGCCGTCAGCGCCATGCTGAGCGCGCTCAACAGCTGGCTGCTGATCAACGCCAGTCTGGA
ATCGGCGATGAGCGCCGCCATCTGGGGCGCCGGCACGCTCAACGGCATGACCTGGAGCAAGGGCCTGCCCTCGGCGCTGT
TCTGCCTGCTGGCCATGCTGGCGGCGATGGCGCTGAAGCCGCGGATGCGGCTCTTGGAAATGGGCGACGACTGCGCCTGC
GCGCTGGGCGTGCCGGCCGAGCGCACCCGGCTGACGCTGATGGGCCTGGGCGTGGCGCTGATCGCCTCCGCCACCGCGGC
CGCCGGGCCGATTTCCTTCATCGCGCTGGCCGCGCCGCAGATCGCCCAGCGCCTGCAGCGCGCGCGCGCCACCAGCCCGC
TTACCGCCGCCTGGACCGGCGCGCTGCTGCTGTTGGCGGCCGACTACGCCGCGCAGCATCTGTTCTACCCGCGCCAACTG
CCGGTTGGCGTCGTCACCATCTGCATCGGCGGCCTGTACCTGCTGTGGCTGCTGCTGCGCCAAACCGGAGGCGCGAAACC
GTGA

Upstream 100 bases:

>100_bases
TGACGCCGGGCGAGCTGCGCGTGTCCATCGTCACCGCCTTCATCGGCGCGCCGGCGCTGATCTGGCTGGCGCGCGGCCAC
GGCGGCGCGGGAGGCCGGAC

Downstream 100 bases:

>100_bases
CCACCCTGTCCTTCAAGCTCAGCCCCGCCGCCGTTGATTCCGCCGCGCCCGTTGCAGGACTGCCGCGTCTCTCCGGCGAC
AGCCTGCGGCTGGGCTACCG

Product: iron-enterobactin transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKAMALRLGHPDGRFNLRLRLDRLWPGLLLMAACAALALISLRAGALHLSIEQVWAALQGRGSRLNVAVVQQWRLPRVAM
ALAIGAALGMSGAIFQSLLRNPLGSPDVVGFNTGAYTGALLVITTIGGSHFQIAGGALAGGLASAALVYLLAWKRGAHGL
RLIIVGIAVSAMLSALNSWLLINASLESAMSAAIWGAGTLNGMTWSKGLPSALFCLLAMLAAMALKPRMRLLEMGDDCAC
ALGVPAERTRLTLMGLGVALIASATAAAGPISFIALAAPQIAQRLQRARATSPLTAAWTGALLLLAADYAAQHLFYPRQL
PVGVVTICIGGLYLLWLLLRQTGGAKP

Sequences:

>Translated_347_residues
MKAMALRLGHPDGRFNLRLRLDRLWPGLLLMAACAALALISLRAGALHLSIEQVWAALQGRGSRLNVAVVQQWRLPRVAM
ALAIGAALGMSGAIFQSLLRNPLGSPDVVGFNTGAYTGALLVITTIGGSHFQIAGGALAGGLASAALVYLLAWKRGAHGL
RLIIVGIAVSAMLSALNSWLLINASLESAMSAAIWGAGTLNGMTWSKGLPSALFCLLAMLAAMALKPRMRLLEMGDDCAC
ALGVPAERTRLTLMGLGVALIASATAAAGPISFIALAAPQIAQRLQRARATSPLTAAWTGALLLLAADYAAQHLFYPRQL
PVGVVTICIGGLYLLWLLLRQTGGAKP
>Mature_347_residues
MKAMALRLGHPDGRFNLRLRLDRLWPGLLLMAACAALALISLRAGALHLSIEQVWAALQGRGSRLNVAVVQQWRLPRVAM
ALAIGAALGMSGAIFQSLLRNPLGSPDVVGFNTGAYTGALLVITTIGGSHFQIAGGALAGGLASAALVYLLAWKRGAHGL
RLIIVGIAVSAMLSALNSWLLINASLESAMSAAIWGAGTLNGMTWSKGLPSALFCLLAMLAAMALKPRMRLLEMGDDCAC
ALGVPAERTRLTLMGLGVALIASATAAAGPISFIALAAPQIAQRLQRARATSPLTAAWTGALLLLAADYAAQHLFYPRQL
PVGVVTICIGGLYLLWLLLRQTGGAKP

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=315, Percent_Identity=57.1428571428571, Blast_Score=295, Evalue=2e-81,
Organism=Escherichia coli, GI1790740, Length=316, Percent_Identity=34.8101265822785, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786347, Length=282, Percent_Identity=32.6241134751773, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790741, Length=295, Percent_Identity=32.8813559322034, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=31.8840579710145, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786805, Length=310, Percent_Identity=34.1935483870968, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36136; Mature: 36136

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMALRLGHPDGRFNLRLRLDRLWPGLLLMAACAALALISLRAGALHLSIEQVWAALQG
CCCEEEEECCCCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHC
RGSRLNVAVVQQWRLPRVAMALAIGAALGMSGAIFQSLLRNPLGSPDVVGFNTGAYTGAL
CCCEEEHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCCCCHHCEE
LVITTIGGSHFQIAGGALAGGLASAALVYLLAWKRGAHGLRLIIVGIAVSAMLSALNSWL
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
LINASLESAMSAAIWGAGTLNGMTWSKGLPSALFCLLAMLAAMALKPRMRLLEMGDDCAC
EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCEE
ALGVPAERTRLTLMGLGVALIASATAAAGPISFIALAAPQIAQRLQRARATSPLTAAWTG
EECCCCHHHEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLLLAADYAAQHLFYPRQLPVGVVTICIGGLYLLWLLLRQTGGAKP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKAMALRLGHPDGRFNLRLRLDRLWPGLLLMAACAALALISLRAGALHLSIEQVWAALQG
CCCEEEEECCCCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHC
RGSRLNVAVVQQWRLPRVAMALAIGAALGMSGAIFQSLLRNPLGSPDVVGFNTGAYTGAL
CCCEEEHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECCCCCHHCEE
LVITTIGGSHFQIAGGALAGGLASAALVYLLAWKRGAHGLRLIIVGIAVSAMLSALNSWL
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
LINASLESAMSAAIWGAGTLNGMTWSKGLPSALFCLLAMLAAMALKPRMRLLEMGDDCAC
EEEHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCEE
ALGVPAERTRLTLMGLGVALIASATAAAGPISFIALAAPQIAQRLQRARATSPLTAAWTG
EECCCCHHHEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLLLAADYAAQHLFYPRQLPVGVVTICIGGLYLLWLLLRQTGGAKP
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]