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The map label for this gene is yrbD [H]

Identifier: 34497680

GI number: 34497680

Start: 2400293

End: 2401387

Strand: Direct

Name: yrbD [H]

Synonym: CV_2225

Alternate gene names: 34497680

Gene position: 2400293-2401387 (Clockwise)

Preceding gene: 34497679

Following gene: 34497681

Centisome position: 50.52

GC content: 68.04

Gene sequence:

>1095_bases
ATGAAGTGGTATGCCTGGCTGTTCGCGCTGACCACGGTGGTGGCCACCGGCGTGCTGCTGCCGGGCATCCAGGCCAACTC
CATCGCCAACTCGATGCAGTCGGCCTTCGGCATCGCGCCCACGGTGACGGCCGCCGTGCTGGCCATCATGCTGGGCTTCA
TCATCTTCGGCGGCGTCAAGCGCATCGCGGTGTTCGCCGGCGCGGTGGTGCCCTTCATGGCGCTGGGCTACATCATCGTC
GCCTGCGTGGTGATCGCGCTCAATATCGAGCAGCTGCCGGGCGTGGTGGCGCTGATCTTCAAGAGCGCCTTCGGTCTGGA
GGCGGGCATGGGCGCGGTGCTGGGCTTCGCCATCCAGTGGGGCGTGAAGCGCGGCATCTATTCCAACGAGGCCGGCCAGG
GCACCGGCCCGCACGCGTCCAGCGCCGCGGCGGTCAGCCATCCGGCCAAGCAGGGCCTGGTGCAGGCGTTCTCGGTCTAC
ATCGACACCCTGTTCGTCTGCTCCGCCACCGCCTTCATGCTGCTGATCACCGGCCAGTACAACGTGCAGGGGCCGGACGG
CGCGGCGCTGTACACCGGCATCGCCGGCGTGGCGGCGGGGCCGGGCTATGTGCAGACCGCGATGGAGAGCATCATGCCTG
GCTTCGGCTCGGTGTTCGTCGCGCTGGCGCTGTTCTTCTTCGCCTTCACCACCATCATCGCCTACTACTACATCGCCGAG
ACCAATGTCGCCTTCATCAACCGCAAGGCGCGGCGGCCGTGGCTGGTGTTCGCGCTGAAGGTGGGCCTGATGGCGGCCAC
CGTCTACGGCACGGTCAAGACCGCCGACCTGGCCTGGGGCCTGGGCGATATCGGCGTCGGCCTGATGGCCTGGCTGAACA
TCGTCGCCATCATCCTGATGCAGAAGCCGGCGCTGGCCTGCCTGCGCGACTACGAGGCGCAGAAGGCGCAGGGCCTGGAT
CCGGTATTCCATCCGGAGAAGCTGGGCATCGTCAACGCCGCCTACTGGGCCGGCCGCCGCGCCGAGAGCAATCTGGACGC
CGAGCGGGATGATCCGCCGCCAGGCGGCAAGCCGGAGCCGGCCAAGGCCGGTTGA

Upstream 100 bases:

>100_bases
GTCAATTAAGCCCGGACTCTAAAGCTCTCTGCTACTGAAAGTGGGGGGACGTCGCCAGTACCGCGGCGGGCCGGCCTTCT
ACATCGAGAAGGGGCTGGGC

Downstream 100 bases:

>100_bases
TTGACGCGACGCCCGCTCACGCGGGCGTTTTTGCGTCGTCCCGGCATTCGGGCATGGGGTTTGCTTTTATTTCCCGCAGA
CCCATTCCGCGAATGAGAGC

Product: sodium/proton-dependent alanine carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKWYAWLFALTTVVATGVLLPGIQANSIANSMQSAFGIAPTVTAAVLAIMLGFIIFGGVKRIAVFAGAVVPFMALGYIIV
ACVVIALNIEQLPGVVALIFKSAFGLEAGMGAVLGFAIQWGVKRGIYSNEAGQGTGPHASSAAAVSHPAKQGLVQAFSVY
IDTLFVCSATAFMLLITGQYNVQGPDGAALYTGIAGVAAGPGYVQTAMESIMPGFGSVFVALALFFFAFTTIIAYYYIAE
TNVAFINRKARRPWLVFALKVGLMAATVYGTVKTADLAWGLGDIGVGLMAWLNIVAIILMQKPALACLRDYEAQKAQGLD
PVFHPEKLGIVNAAYWAGRRAESNLDAERDDPPPGGKPEPAKAG

Sequences:

>Translated_364_residues
MKWYAWLFALTTVVATGVLLPGIQANSIANSMQSAFGIAPTVTAAVLAIMLGFIIFGGVKRIAVFAGAVVPFMALGYIIV
ACVVIALNIEQLPGVVALIFKSAFGLEAGMGAVLGFAIQWGVKRGIYSNEAGQGTGPHASSAAAVSHPAKQGLVQAFSVY
IDTLFVCSATAFMLLITGQYNVQGPDGAALYTGIAGVAAGPGYVQTAMESIMPGFGSVFVALALFFFAFTTIIAYYYIAE
TNVAFINRKARRPWLVFALKVGLMAATVYGTVKTADLAWGLGDIGVGLMAWLNIVAIILMQKPALACLRDYEAQKAQGLD
PVFHPEKLGIVNAAYWAGRRAESNLDAERDDPPPGGKPEPAKAG
>Mature_364_residues
MKWYAWLFALTTVVATGVLLPGIQANSIANSMQSAFGIAPTVTAAVLAIMLGFIIFGGVKRIAVFAGAVVPFMALGYIIV
ACVVIALNIEQLPGVVALIFKSAFGLEAGMGAVLGFAIQWGVKRGIYSNEAGQGTGPHASSAAAVSHPAKQGLVQAFSVY
IDTLFVCSATAFMLLITGQYNVQGPDGAALYTGIAGVAAGPGYVQTAMESIMPGFGSVFVALALFFFAFTTIIAYYYIAE
TNVAFINRKARRPWLVFALKVGLMAATVYGTVKTADLAWGLGDIGVGLMAWLNIVAIILMQKPALACLRDYEAQKAQGLD
PVFHPEKLGIVNAAYWAGRRAESNLDAERDDPPPGGKPEPAKAG

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=333, Percent_Identity=33.6336336336336, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 38167; Mature: 38167

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]