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The map label for this gene is arcB [H]

Identifier: 34497668

GI number: 34497668

Start: 2382413

End: 2384617

Strand: Reverse

Name: arcB [H]

Synonym: CV_2213

Alternate gene names: 34497668

Gene position: 2384617-2382413 (Counterclockwise)

Preceding gene: 34497669

Following gene: 34497649

Centisome position: 50.19

GC content: 64.58

Gene sequence:

>2205_bases
ATGACTCAGGGCAAATGGCAATCCACTTCCTGGCGCCTGTTGCTGGCCATAGGCATCGCGCTATCCTGCGTGTTCGCCGG
CGTCGCCTACATCCAGCATCGCCAGTCCCAGATTCTGACCAACGCGGTGCTGTATCAGGACGACAACATCATTTGGGCCT
ATTTCCAGCTGGAAGCGGAAAACCTGCACCTGCAAACCGCGCTCCACGCCGCGCAGCACGATCAGATGTCGCCCGAGGAC
CTGCAGCAGCGCTACGACATCTTCGTCAGCCGCGTCGGCATCATCCGCGGCGGCCAATATCGCAGGCTGCTGCAAGACCA
GCCCCAGTTCCTGCTGATGCAAGCCCGGCTCGACGCCTTCATCCGGCAGGGAGACGCCTATTTCAGCGCCGCCAACGCGG
CGAACGACCACGCGCGCCAGGCCAGGCTGGAAAGGCTGTCCGCCTCGCTGTCGGACGGGCTGCACGATCTGTCGCTGCAG
GCCAACCAGGCCGCGGCCCTGCAAGTGGACAACCGCAACCGCACCATGCAGCAGTACATCGCGGTCAGCAACTGGCTGAT
GACATTCGAATGGCTGCTGATCTTCGGCTTCGGCTTCACCGTGATTCGCCAGCTGCGCCAGCTGGAAAAACGCCGGCAGA
CCCTGGAAACGCTGACCGACAATCTGGAAGAAGCCCGCAGCCAGGCCGAGGCGGGCAGCCTGGCCAAGAGCGCCTTCCTC
GCCAACATGAGCCACGAAATCCGCACGCCGCTCAACGGCGTCCTCGGCATGCTGGCGCTGCTGGCCGACAGCCATCCCAG
CGCCAGCCAGGCCAACTACATCCGTACCGCGGAAGAGTCGGCTCGCCATCTGCTCTTGCTGCTCAACGACGTGCTGGACG
CCAGCAAGCTGGAGTCCGGCAAGCTTGAACTGGCACCGGTCACCTGCAATCTGGCCTATTTGCTGCGCCAGGTGACCAAT
TTGATGAACGCCCAGGCTCAAGCCAAGGGACTGATGCTGAACCTGGAAATGGCTTCGGAAATACCGCAATGGGTGGAGCT
GGACCCCACCCGTTTGCGCCAGATAGTGCTCAACCTGCTGAGCAACGCCATCAAGTTCACCGAGCGGGGCGGCGTCACCG
TGCACGCGTCGGCGACGGCGGGAGAGCAGCCCGGCACGGCTCAGCTGCTGCTGGTGGTCACCGATACCGGCATAGGCATG
GACCAGGCTACCCTCTCCAAGCTGTTCAAGCGTTTTTCCCAAGGCGACGGCTCCACCGCCCGCCAGTTCGGCGGCAGCGG
ACTCGGTCTGGAAATCTCCCAAAGCCTGGCCCAGCTGATGGGGGGCGGCATATCGGTGAGCAGCGTTCCGGGCCAGGGCA
GTTGCTTCCAGCTGACGCTGCCGCTCCGGGTGATCGCCGCGCCCGACCTGCCTCCCGAAACCGCGGAGGCGTCCTTCAGC
CACGATGTGCTGGGCAGGCCGCTGCGCATCCTGGTAGTGGACGACAACGCGGTGAACCGCAAGTATCTGCAAGCGCTGCT
GGAAAGGCTGAACCAGCAGCCTACGCTGGCCTCGGATGGTCCGGAAGCCTTGCGCCTGGCCGCCAGCCAGCCCTTCGACC
TGACCTTGATGGACCTGCACATGCCGGGAATGGACGGCGCGGAGACCGCGCGCAGGCTTCGGAAAGAGGCGCAAACGCCA
GGAATGCCCATCGTCGCGCTGACGGCGGACGCGTTCCCGGAGACGCGCCAGCAGATGCTGGCGCAGGGCCTGGACGACTT
CCTGACGAAACCGCTGGGACGCGACCAGTTGCTGGCGGTGCTCCAGAAGCTATTCCCCCCCGAACCCGGCGCCGCGCCCC
AGACAAGGGAGGAGCCGGCCCTGGATGCCCGCACCATCGCGGACTTCATCGAACTGCTGTCTGAGGAGCAATACCGGCAA
TTGGTGGAGCAATACTTCTCCAGCCACCAGGAATCCATCCGGCAACTGCAGCTCAATCAGCAGCAGCCGGATCGGGAGAG
CCTGTTCCACCTCGCGCACGGCCTGAAGGGCGGCGCGGTGACGCTGGGGTTCGCCAGCCTGGCGCAGCGCTGCCTGGAGC
TGGAGCAGCAATCGGTGCAGTCCAATTGCACGCCTGCGCCGCAAATCGCACTGGTGATCGCCCAGTTCCAGGCCACCCGG
CAGGCCTGCATCGCGCAGGGGTATCTGCATTGTCAGGTGGGTTAG

Upstream 100 bases:

>100_bases
TTCATCGTCTACCCCTACGACAGCCAGGCCGTGCTGCGTTCGGAGGTCTATTACAACCGTTCCGCCTGGCAATTGAAGTC
GCTGCAGGTCGAGTAACGCC

Downstream 100 bases:

>100_bases
CGCCAGCCTTGCCGCGCAATGGCTGTCGGAGCCGACAGAGCGCAGAAAAAGACGGAAGAAGCTCGGGAATCGTTGCCCCG
CGCCTCAGGCCACCCTCACC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 734; Mature: 733

Protein sequence:

>734_residues
MTQGKWQSTSWRLLLAIGIALSCVFAGVAYIQHRQSQILTNAVLYQDDNIIWAYFQLEAENLHLQTALHAAQHDQMSPED
LQQRYDIFVSRVGIIRGGQYRRLLQDQPQFLLMQARLDAFIRQGDAYFSAANAANDHARQARLERLSASLSDGLHDLSLQ
ANQAAALQVDNRNRTMQQYIAVSNWLMTFEWLLIFGFGFTVIRQLRQLEKRRQTLETLTDNLEEARSQAEAGSLAKSAFL
ANMSHEIRTPLNGVLGMLALLADSHPSASQANYIRTAEESARHLLLLLNDVLDASKLESGKLELAPVTCNLAYLLRQVTN
LMNAQAQAKGLMLNLEMASEIPQWVELDPTRLRQIVLNLLSNAIKFTERGGVTVHASATAGEQPGTAQLLLVVTDTGIGM
DQATLSKLFKRFSQGDGSTARQFGGSGLGLEISQSLAQLMGGGISVSSVPGQGSCFQLTLPLRVIAAPDLPPETAEASFS
HDVLGRPLRILVVDDNAVNRKYLQALLERLNQQPTLASDGPEALRLAASQPFDLTLMDLHMPGMDGAETARRLRKEAQTP
GMPIVALTADAFPETRQQMLAQGLDDFLTKPLGRDQLLAVLQKLFPPEPGAAPQTREEPALDARTIADFIELLSEEQYRQ
LVEQYFSSHQESIRQLQLNQQQPDRESLFHLAHGLKGGAVTLGFASLAQRCLELEQQSVQSNCTPAPQIALVIAQFQATR
QACIAQGYLHCQVG

Sequences:

>Translated_734_residues
MTQGKWQSTSWRLLLAIGIALSCVFAGVAYIQHRQSQILTNAVLYQDDNIIWAYFQLEAENLHLQTALHAAQHDQMSPED
LQQRYDIFVSRVGIIRGGQYRRLLQDQPQFLLMQARLDAFIRQGDAYFSAANAANDHARQARLERLSASLSDGLHDLSLQ
ANQAAALQVDNRNRTMQQYIAVSNWLMTFEWLLIFGFGFTVIRQLRQLEKRRQTLETLTDNLEEARSQAEAGSLAKSAFL
ANMSHEIRTPLNGVLGMLALLADSHPSASQANYIRTAEESARHLLLLLNDVLDASKLESGKLELAPVTCNLAYLLRQVTN
LMNAQAQAKGLMLNLEMASEIPQWVELDPTRLRQIVLNLLSNAIKFTERGGVTVHASATAGEQPGTAQLLLVVTDTGIGM
DQATLSKLFKRFSQGDGSTARQFGGSGLGLEISQSLAQLMGGGISVSSVPGQGSCFQLTLPLRVIAAPDLPPETAEASFS
HDVLGRPLRILVVDDNAVNRKYLQALLERLNQQPTLASDGPEALRLAASQPFDLTLMDLHMPGMDGAETARRLRKEAQTP
GMPIVALTADAFPETRQQMLAQGLDDFLTKPLGRDQLLAVLQKLFPPEPGAAPQTREEPALDARTIADFIELLSEEQYRQ
LVEQYFSSHQESIRQLQLNQQQPDRESLFHLAHGLKGGAVTLGFASLAQRCLELEQQSVQSNCTPAPQIALVIAQFQATR
QACIAQGYLHCQVG
>Mature_733_residues
TQGKWQSTSWRLLLAIGIALSCVFAGVAYIQHRQSQILTNAVLYQDDNIIWAYFQLEAENLHLQTALHAAQHDQMSPEDL
QQRYDIFVSRVGIIRGGQYRRLLQDQPQFLLMQARLDAFIRQGDAYFSAANAANDHARQARLERLSASLSDGLHDLSLQA
NQAAALQVDNRNRTMQQYIAVSNWLMTFEWLLIFGFGFTVIRQLRQLEKRRQTLETLTDNLEEARSQAEAGSLAKSAFLA
NMSHEIRTPLNGVLGMLALLADSHPSASQANYIRTAEESARHLLLLLNDVLDASKLESGKLELAPVTCNLAYLLRQVTNL
MNAQAQAKGLMLNLEMASEIPQWVELDPTRLRQIVLNLLSNAIKFTERGGVTVHASATAGEQPGTAQLLLVVTDTGIGMD
QATLSKLFKRFSQGDGSTARQFGGSGLGLEISQSLAQLMGGGISVSSVPGQGSCFQLTLPLRVIAAPDLPPETAEASFSH
DVLGRPLRILVVDDNAVNRKYLQALLERLNQQPTLASDGPEALRLAASQPFDLTLMDLHMPGMDGAETARRLRKEAQTPG
MPIVALTADAFPETRQQMLAQGLDDFLTKPLGRDQLLAVLQKLFPPEPGAAPQTREEPALDARTIADFIELLSEEQYRQL
VEQYFSSHQESIRQLQLNQQQPDRESLFHLAHGLKGGAVTLGFASLAQRCLELEQQSVQSNCTPAPQIALVIAQFQATRQ
ACIAQGYLHCQVG

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=628, Percent_Identity=31.0509554140127, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87081816, Length=518, Percent_Identity=33.5907335907336, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI1788713, Length=493, Percent_Identity=33.4685598377282, Blast_Score=207, Evalue=3e-54,
Organism=Escherichia coli, GI1789149, Length=300, Percent_Identity=39.3333333333333, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=36.3265306122449, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1786912, Length=265, Percent_Identity=29.0566037735849, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=28.6290322580645, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=332, Percent_Identity=25.6024096385542, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.6324786324786, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=28.1938325991189, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.1938325991189, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=39.6551724137931, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=26.1904761904762, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=35.2459016393443, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=26.7206477732794, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787375, Length=132, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=99, Percent_Identity=40.4040404040404, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80907; Mature: 80776

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQGKWQSTSWRLLLAIGIALSCVFAGVAYIQHRQSQILTNAVLYQDDNIIWAYFQLEAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEECC
NLHLQTALHAAQHDQMSPEDLQQRYDIFVSRVGIIRGGQYRRLLQDQPQFLLMQARLDAF
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHH
IRQGDAYFSAANAANDHARQARLERLSASLSDGLHDLSLQANQAAALQVDNRNRTMQQYI
HHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHH
AVSNWLMTFEWLLIFGFGFTVIRQLRQLEKRRQTLETLTDNLEEARSQAEAGSLAKSAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMSHEIRTPLNGVLGMLALLADSHPSASQANYIRTAEESARHLLLLLNDVLDASKLESG
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLELAPVTCNLAYLLRQVTNLMNAQAQAKGLMLNLEMASEIPQWVELDPTRLRQIVLNLL
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCHHHCCCHHHHHHHHHHHH
SNAIKFTERGGVTVHASATAGEQPGTAQLLLVVTDTGIGMDQATLSKLFKRFSQGDGSTA
HHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
RQFGGSGLGLEISQSLAQLMGGGISVSSVPGQGSCFQLTLPLRVIAAPDLPPETAEASFS
HHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECEEEEECCCCCCCCCCCCCC
HDVLGRPLRILVVDDNAVNRKYLQALLERLNQQPTLASDGPEALRLAASQPFDLTLMDLH
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEEE
MPGMDGAETARRLRKEAQTPGMPIVALTADAFPETRQQMLAQGLDDFLTKPLGRDQLLAV
CCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LQKLFPPEPGAAPQTREEPALDARTIADFIELLSEEQYRQLVEQYFSSHQESIRQLQLNQ
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
QQPDRESLFHLAHGLKGGAVTLGFASLAQRCLELEQQSVQSNCTPAPQIALVIAQFQATR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QACIAQGYLHCQVG
HHHHHCCCEEEECC
>Mature Secondary Structure 
TQGKWQSTSWRLLLAIGIALSCVFAGVAYIQHRQSQILTNAVLYQDDNIIWAYFQLEAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEEEECC
NLHLQTALHAAQHDQMSPEDLQQRYDIFVSRVGIIRGGQYRRLLQDQPQFLLMQARLDAF
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHH
IRQGDAYFSAANAANDHARQARLERLSASLSDGLHDLSLQANQAAALQVDNRNRTMQQYI
HHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHH
AVSNWLMTFEWLLIFGFGFTVIRQLRQLEKRRQTLETLTDNLEEARSQAEAGSLAKSAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMSHEIRTPLNGVLGMLALLADSHPSASQANYIRTAEESARHLLLLLNDVLDASKLESG
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLELAPVTCNLAYLLRQVTNLMNAQAQAKGLMLNLEMASEIPQWVELDPTRLRQIVLNLL
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCHHHCCCHHHHHHHHHHHH
SNAIKFTERGGVTVHASATAGEQPGTAQLLLVVTDTGIGMDQATLSKLFKRFSQGDGSTA
HHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHH
RQFGGSGLGLEISQSLAQLMGGGISVSSVPGQGSCFQLTLPLRVIAAPDLPPETAEASFS
HHCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCEEEEEECEEEEECCCCCCCCCCCCCC
HDVLGRPLRILVVDDNAVNRKYLQALLERLNQQPTLASDGPEALRLAASQPFDLTLMDLH
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEEEEE
MPGMDGAETARRLRKEAQTPGMPIVALTADAFPETRQQMLAQGLDDFLTKPLGRDQLLAV
CCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LQKLFPPEPGAAPQTREEPALDARTIADFIELLSEEQYRQLVEQYFSSHQESIRQLQLNQ
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
QQPDRESLFHLAHGLKGGAVTLGFASLAQRCLELEQQSVQSNCTPAPQIALVIAQFQATR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QACIAQGYLHCQVG
HHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]